NO20062262L - Cykloalkylderivater av 3-hydroksy-4-pyridinoner - Google Patents
Cykloalkylderivater av 3-hydroksy-4-pyridinonerInfo
- Publication number
- NO20062262L NO20062262L NO20062262A NO20062262A NO20062262L NO 20062262 L NO20062262 L NO 20062262L NO 20062262 A NO20062262 A NO 20062262A NO 20062262 A NO20062262 A NO 20062262A NO 20062262 L NO20062262 L NO 20062262L
- Authority
- NO
- Norway
- Prior art keywords
- alkyl
- cycloalkyl
- group
- iron
- proviso
- Prior art date
Links
- 125000000753 cycloalkyl group Chemical group 0.000 title abstract 3
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 8
- 229910052742 iron Inorganic materials 0.000 abstract 4
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000002757 morpholinyl group Chemical group 0.000 abstract 2
- 125000004193 piperazinyl group Chemical group 0.000 abstract 2
- 125000003386 piperidinyl group Chemical group 0.000 abstract 2
- 125000000719 pyrrolidinyl group Chemical group 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 239000002738 chelating agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229910021645 metal ion Inorganic materials 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ529657A NZ529657A (en) | 2003-11-20 | 2003-11-20 | Iron chelating cycloalkyl derivatives of 3-hydroxy-4-pyridinones |
| PCT/CA2004/001986 WO2005049609A1 (en) | 2003-11-20 | 2004-11-18 | Cycloalkyl derivatives of 3-hydroxy-4-pyridinones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20062262L true NO20062262L (no) | 2006-08-11 |
Family
ID=31987701
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20062262A NO20062262L (no) | 2003-11-20 | 2006-05-19 | Cykloalkylderivater av 3-hydroksy-4-pyridinoner |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US7410985B2 (pt) |
| EP (1) | EP1687298B1 (pt) |
| KR (1) | KR101166113B1 (pt) |
| CN (1) | CN100448873C (pt) |
| AU (2) | AU2004291184B2 (pt) |
| BR (1) | BRPI0416703A (pt) |
| CA (1) | CA2546781C (pt) |
| IL (1) | IL175654A (pt) |
| MX (1) | MXPA06005594A (pt) |
| NO (1) | NO20062262L (pt) |
| NZ (1) | NZ529657A (pt) |
| RU (1) | RU2345992C2 (pt) |
| TN (1) | TNSN06142A1 (pt) |
| UA (1) | UA84178C2 (pt) |
| WO (1) | WO2005049609A1 (pt) |
| ZA (1) | ZA200604998B (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2488034C (en) | 2004-11-19 | 2009-10-06 | Apotex Inc. | Process for the manufacture of 3-hydroxy-n-alkyl-1-cycloalkyl-6-alkyl-4-oxo-1,4-dihydropyridine-2-carboxamide and its related analogues |
| DE102006043929B4 (de) * | 2006-09-14 | 2016-10-06 | Spawnt Private S.À.R.L. | Verfahren zur Herstellung von festen Polysilanmischungen |
| WO2010011814A1 (en) * | 2008-07-25 | 2010-01-28 | Smithkline Beecham Corporation | Chemical compounds |
| CN101975767B (zh) * | 2010-08-13 | 2012-12-05 | 同济大学 | 一种测定水环境中溶解性有机物与金属离子结合潜势的方法 |
| CA2826192A1 (en) * | 2011-01-31 | 2012-08-09 | The Government Of The United States, As Represented By The Secretary Of The Army | Methods and compositions for treating bacterial infections with iron chelators |
| CN102603964B (zh) * | 2012-01-15 | 2014-03-05 | 浙江工商大学 | 水溶性聚合物铁螯合剂及其制备方法和用途 |
| CN105030819B (zh) * | 2015-07-06 | 2019-04-05 | 中国科学技术大学 | 一种3-羟基-4-吡啶酮类高分子铁螯合剂的用途 |
| CN116621775B (zh) * | 2023-05-24 | 2025-09-09 | 浙江大学 | 含羟基吡啶酮侧链的2-氨基-5-羟基四氢萘衍生物及制备和应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8308054D0 (en) * | 1983-03-24 | 1983-05-05 | Hider R C | Pharmaceutical compositions |
| GB9217099D0 (en) * | 1992-08-12 | 1992-09-23 | British Tech Group | Pharmaceutical compositions |
| ES2244967T3 (es) * | 1995-09-29 | 2005-12-16 | Novartis Ag | Nuevas hidroxipiridinonas. |
| US6448273B1 (en) * | 1997-05-29 | 2002-09-10 | Btg International Limited | Orally active iron (III) chelators |
| GB9711093D0 (en) * | 1997-05-29 | 1997-07-23 | British Tech Group | Novel orally active iron (III) chelators |
| US6488273B2 (en) | 2001-04-20 | 2002-12-03 | Btm Corporation | Powered pivot unit |
| US6426418B1 (en) * | 2001-11-02 | 2002-07-30 | Apotex, Inc. | Processes for the manufacturing of 3-hydroxy-N,1,6-trialkyl-4-oxo-1,4-dihydropyridine-2-carboxamide |
| CA2379370A1 (en) | 2002-03-28 | 2003-09-28 | Apotex Inc. | Carboxylic acid derivatives of 3-hydroxy-4-oxo-1,4-dihydropyridine as iron chelators |
-
2003
- 2003-11-20 NZ NZ529657A patent/NZ529657A/en not_active IP Right Cessation
-
2004
- 2004-11-18 US US10/580,011 patent/US7410985B2/en not_active Expired - Fee Related
- 2004-11-18 AU AU2004291184A patent/AU2004291184B2/en not_active Ceased
- 2004-11-18 EP EP04818733A patent/EP1687298B1/en not_active Expired - Lifetime
- 2004-11-18 BR BRPI0416703-1A patent/BRPI0416703A/pt not_active IP Right Cessation
- 2004-11-18 KR KR1020067012201A patent/KR101166113B1/ko not_active Expired - Fee Related
- 2004-11-18 RU RU2006121547/04A patent/RU2345992C2/ru not_active IP Right Cessation
- 2004-11-18 CN CNB2004800392676A patent/CN100448873C/zh not_active Expired - Fee Related
- 2004-11-18 CA CA2546781A patent/CA2546781C/en not_active Expired - Fee Related
- 2004-11-18 MX MXPA06005594A patent/MXPA06005594A/es active IP Right Grant
- 2004-11-18 WO PCT/CA2004/001986 patent/WO2005049609A1/en not_active Ceased
- 2004-11-18 UA UAA200606922A patent/UA84178C2/ru unknown
-
2006
- 2006-05-15 IL IL175654A patent/IL175654A/en not_active IP Right Cessation
- 2006-05-17 TN TNP2006000142A patent/TNSN06142A1/en unknown
- 2006-05-19 NO NO20062262A patent/NO20062262L/no not_active Application Discontinuation
- 2006-06-19 ZA ZA200604998A patent/ZA200604998B/en unknown
-
2008
- 2008-05-09 US US12/149,853 patent/US8097624B2/en not_active Expired - Fee Related
-
2010
- 2010-11-19 AU AU2010246323A patent/AU2010246323A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2010246323A1 (en) | 2010-12-09 |
| IL175654A0 (en) | 2006-09-05 |
| US7410985B2 (en) | 2008-08-12 |
| NZ529657A (en) | 2004-07-30 |
| EP1687298A4 (en) | 2007-10-17 |
| AU2004291184A1 (en) | 2005-06-02 |
| EP1687298B1 (en) | 2012-12-26 |
| BRPI0416703A (pt) | 2007-01-16 |
| MXPA06005594A (es) | 2006-12-19 |
| TNSN06142A1 (en) | 2007-11-15 |
| UA84178C2 (en) | 2008-09-25 |
| KR101166113B1 (ko) | 2012-07-27 |
| CN100448873C (zh) | 2009-01-07 |
| ZA200604998B (en) | 2007-09-26 |
| CA2546781C (en) | 2012-05-15 |
| RU2006121547A (ru) | 2007-12-27 |
| WO2005049609A1 (en) | 2005-06-02 |
| US8097624B2 (en) | 2012-01-17 |
| US20090170850A1 (en) | 2009-07-02 |
| AU2004291184B2 (en) | 2010-08-26 |
| RU2345992C2 (ru) | 2009-02-10 |
| EP1687298A1 (en) | 2006-08-09 |
| IL175654A (en) | 2011-10-31 |
| CN1926135A (zh) | 2007-03-07 |
| KR20060096155A (ko) | 2006-09-07 |
| US20070082904A1 (en) | 2007-04-12 |
| CA2546781A1 (en) | 2005-06-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |