NO20062342L - Metode for transdermal levering av permeante substanser - Google Patents

Metode for transdermal levering av permeante substanser

Info

Publication number
NO20062342L
NO20062342L NO20062342A NO20062342A NO20062342L NO 20062342 L NO20062342 L NO 20062342L NO 20062342 A NO20062342 A NO 20062342A NO 20062342 A NO20062342 A NO 20062342A NO 20062342 L NO20062342 L NO 20062342L
Authority
NO
Norway
Prior art keywords
transdermal delivery
permeant
permeant substances
substances
delivery opening
Prior art date
Application number
NO20062342A
Other languages
English (en)
Inventor
Jonathan A Eppstein
Allan Smith
Bernadette Messier
Zoran Novakovic
Stuart Mcrae
Original Assignee
Altea Therapeutics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altea Therapeutics Corp filed Critical Altea Therapeutics Corp
Publication of NO20062342L publication Critical patent/NO20062342L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0046Ear
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0412Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061Methods for using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Electrotherapy Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Det beskrives en fremgangsmåte for avlevering av permeante substanser transdermalt inn i en membran hos et pattedyr, som omfatter dannelse av minst én avleveringsåpning i hudvevet, hvor den minst ene avleveringsåpning har en midlere åpningsdybde på mellom ca. 40 og ca. 90 mikron.
NO20062342A 2003-10-24 2006-05-23 Metode for transdermal levering av permeante substanser NO20062342L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/691,968 US8016811B2 (en) 2003-10-24 2003-10-24 Method for transdermal delivery of permeant substances
PCT/US2004/034715 WO2005042051A2 (en) 2003-10-24 2004-10-21 Method for transdermal delivery of permeant substances

Publications (1)

Publication Number Publication Date
NO20062342L true NO20062342L (no) 2006-07-24

Family

ID=34521990

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20062342A NO20062342L (no) 2003-10-24 2006-05-23 Metode for transdermal levering av permeante substanser

Country Status (11)

Country Link
US (4) US8016811B2 (no)
EP (2) EP1689483A4 (no)
JP (1) JP5032121B2 (no)
KR (1) KR101232225B1 (no)
CN (1) CN1893998A (no)
AU (1) AU2004284914B2 (no)
CA (1) CA2543534C (no)
IL (1) IL175088A0 (no)
NO (1) NO20062342L (no)
RU (3) RU2366467C2 (no)
WO (1) WO2005042051A2 (no)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002330406A1 (en) * 2002-09-13 2004-04-30 Fujitsu Limited Biosensing instrument and method and identifying device having biosensing function
US8016811B2 (en) * 2003-10-24 2011-09-13 Altea Therapeutics Corporation Method for transdermal delivery of permeant substances
US7249815B2 (en) * 2004-01-30 2007-07-31 Hewlett-Packard Development Company, L.P. Nozzle distribution
TWI419717B (zh) * 2005-06-17 2013-12-21 Altea Therapeutics Corp 滲透傳送系統及其使用方法
US20080234626A1 (en) * 2006-04-26 2008-09-25 Chelak Todd M Multi-stage microporation device
BRPI0916150B1 (pt) * 2008-11-18 2019-09-24 3M Innovative Properties Company Arranjo de microagulhas ocas
RU2438585C1 (ru) * 2010-04-27 2012-01-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Ростовский государственный медицинский университет" Министерства здравоохранения и социального развития Российской Федерации (ГБОУ ВПО РостГМУ Минздравсоцразвития России) Способ определения мест инъекций инсулина
BR112014009713A2 (pt) * 2011-10-27 2017-04-18 Kimberly Clark Co administração transdérmica de agentes bioativos de alta viscosidade
US8962028B2 (en) 2012-10-18 2015-02-24 MiCal Pharmaceuticals LLC—H Series, a Series of MiCal Pharmaceuticals LLC, a Multi-Division Limited Liability Company Topical steroid composition and method
RU2515405C1 (ru) * 2012-10-29 2014-05-10 Объединенный Институт Ядерных Исследований Устройство для радиационной защиты биологических объектов в эксперименте
RU2534521C2 (ru) * 2012-11-27 2014-11-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Национальный исследовательский Томский государственный университет" (ТГУ) Способ трансдермального введения инсулина и устройство для его осуществления
EP2969613B1 (en) 2013-03-13 2018-08-08 Bergstrom, Inc. Air conditioning system utilizing heat recovery ventilation for fresh air supply and climate control
EP2969615B1 (en) 2013-03-13 2021-06-02 Bergstrom, Inc. Air conditioning system utilizing thermal capacity from expansion of compressed fluid
WO2015115496A1 (ja) 2014-01-29 2015-08-06 日東電工株式会社 皮膚透過促進組成物、経皮投与製剤及び貼付製剤
US20170000751A1 (en) 2014-01-29 2017-01-05 Nitto Denko Corporation Composition for accelerating penetration through skin, preparation for transdermal administration, and skin patch preparation
US11351347B2 (en) 2014-04-23 2022-06-07 Vacu-Site Medical, Inc. Vacuum-assisted drug delivery device and method
CN106413642B (zh) 2014-04-23 2019-03-08 塞罗斯医学有限责任公司 真空辅助药物递送装置
JP7096591B2 (ja) * 2016-02-05 2022-07-06 パスポート テクノロジーズ、インコーポレイテッド 経皮透過物投与装置
US11448441B2 (en) 2017-07-27 2022-09-20 Bergstrom, Inc. Refrigerant system for cooling electronics
WO2019055594A1 (en) 2017-09-13 2019-03-21 North Carolina State University BRUSHING ADIPOSE TISSUE INDUCED LOCALLY BY MICRO-NEEDLE STAMPS FOR THE TREATMENT OF OBESITY
US12390422B2 (en) 2019-06-28 2025-08-19 Passport Technologies, Inc. Transdermal drug delivery patch, drug delivery system and drug delivery
CN114375181B (zh) * 2019-06-28 2025-10-31 帕斯帕特技术有限公司 用于控制向细丝装置递送能量的方法和系统
AU2020306024B2 (en) 2019-06-28 2025-02-27 Passport Technologies, Inc. Triptan microporation delivery system
US12605539B2 (en) 2019-06-28 2026-04-21 Passport Technologies, Inc. Methods and systems for delivering drugs through skin of a body
CN114949576B (zh) * 2022-07-27 2022-11-11 北京神州汉方医药科技有限公司 用于皮肤给药的给药控制装置
CN116173390B (zh) * 2022-12-30 2026-03-24 苏州纳通生物纳米技术有限公司 便于定量给药的处理皮肤至稳态的方法

Family Cites Families (146)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3551554A (en) 1968-08-16 1970-12-29 Crown Zellerbach Corp Enhancing tissue penetration of physiologically active agents with dmso
US3711606A (en) 1970-09-02 1973-01-16 Crown Zellerbach Corp Enhancing tissue penetration of physiologically active steroidal agents with dmso
US3711602A (en) 1970-10-30 1973-01-16 Crown Zellerbach Corp Compositions for topical application for enhancing tissue penetration of physiologically active agents with dmso
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
USD259351S (en) 1978-10-16 1981-05-26 Deboer James H Gameboard
US4340048A (en) 1981-03-28 1982-07-20 Alza Corporation Self-driven hypodermic injector
US4522622A (en) 1982-12-23 1985-06-11 Alza Corporation Multiple fluid pulse dispenser
US4537776A (en) 1983-06-21 1985-08-27 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone
US5651768A (en) 1983-08-18 1997-07-29 Drug Delivery Systems, Inc. Transdermal drug applicator and electrodes therefor
US4921475A (en) * 1983-08-18 1990-05-01 Drug Delivery Systems Inc. Transdermal drug patch with microtubes
US5224928A (en) 1983-08-18 1993-07-06 Drug Delivery Systems Inc. Mounting system for transdermal drug applicator
CA1262564A (en) 1983-09-01 1989-10-31 Minoru Sasaki Iontophoresis device
US4557943A (en) 1983-10-31 1985-12-10 Advanced Semiconductor Materials America, Inc. Metal-silicide deposition using plasma-enhanced chemical vapor deposition
GB8401059D0 (en) 1984-01-16 1984-02-15 Exeter University Of Fixation of implants in bone
US4758081A (en) 1985-07-18 1988-07-19 Bausch & Lomb Incorporated Control of laser photocoagulation using Raman radiation
WO1987000413A1 (en) 1985-07-26 1987-01-29 Microtech Medical Company, Inc. Non-invasive collection means and method
US4775361A (en) 1986-04-10 1988-10-04 The General Hospital Corporation Controlled removal of human stratum corneum by pulsed laser to enhance percutaneous transport
US4767402A (en) 1986-07-08 1988-08-30 Massachusetts Institute Of Technology Ultrasound enhancement of transdermal drug delivery
US5041109A (en) 1986-10-27 1991-08-20 University Of Florida Laser apparatus for the recanalization of vessels and the treatment of other cardiac conditions
US4860743A (en) 1986-10-27 1989-08-29 University Of Florida Laser method and apparatus for the recanalization of vessels and the treatment of other cardiac conditions
US4863970A (en) 1986-11-14 1989-09-05 Theratech, Inc. Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols
JPS63132889A (ja) 1986-11-21 1988-06-04 Tanabe Seiyaku Co Ltd キナゾリノン誘導体
US5006342A (en) 1986-12-22 1991-04-09 Cygnus Corporation Resilient transdermal drug delivery device
DD259351A1 (de) 1987-04-02 1988-08-24 Univ Schiller Jena Verfahren zur herstellung eines arzneimittels fuer die thermische behandlung von tumoroesem gewebe
US4820720A (en) 1987-08-24 1989-04-11 Alza Corporation Transdermal drug composition with dual permeation enhancers
AU614092B2 (en) 1987-09-11 1991-08-22 Paul Max Grinwald Improved method and apparatus for enhanced drug permeation of skin
US4942883A (en) 1987-09-29 1990-07-24 Newman Martin H Drug delivery device
US5749847A (en) 1988-01-21 1998-05-12 Massachusetts Institute Of Technology Delivery of nucleotides into organisms by electroporation
US5547467A (en) 1988-01-21 1996-08-20 Massachusettes Institute Of Technology Method for rapid temporal control of molecular transport across tissue
DE68925030T2 (de) 1988-01-21 1996-07-25 Massachusetts Inst Technology Molekültransport durch gewebe mit der verwendung von elektroporation.
US5362307A (en) 1989-01-24 1994-11-08 The Regents Of The University Of California Method for the iontophoretic non-invasive-determination of the in vivo concentration level of an inorganic or organic substance
JP2861076B2 (ja) 1988-08-05 1999-02-24 住友化学工業株式会社 殺虫性水性液剤
US5088977A (en) 1988-12-21 1992-02-18 Drug Delivery Systems Inc. Electrical transdermal drug applicator with counteractor and method of drug delivery
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US4973468A (en) 1989-03-22 1990-11-27 Cygnus Research Corporation Skin permeation enhancer compositions
US5139023A (en) 1989-06-02 1992-08-18 Theratech Inc. Apparatus and method for noninvasive blood glucose monitoring
US5169389A (en) 1989-06-16 1992-12-08 Science, Inc. Fluid delivery apparatus
EP0429842B1 (en) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
US5190558A (en) 1989-11-08 1993-03-02 Nec Corporation Method of eliminating stratum corneum from the skin and an instrument to be used therefor
US5697901A (en) 1989-12-14 1997-12-16 Elof Eriksson Gene delivery by microneedle injection
US5016615A (en) 1990-02-20 1991-05-21 Riverside Research Institute Local application of medication with ultrasound
US5231975A (en) 1990-02-23 1993-08-03 Cygnus Therapeutic Systems Ultrasound-enhanced delivery of materials into and through the skin
US5115805A (en) 1990-02-23 1992-05-26 Cygnus Therapeutic Systems Ultrasound-enhanced delivery of materials into and through the skin
US5264618A (en) 1990-04-19 1993-11-23 Vical, Inc. Cationic lipids for intracellular delivery of biologically active molecules
US5092864A (en) 1990-04-30 1992-03-03 Microfab Technologies, Inc. Method and apparatus for improved laser surgery
GB9014307D0 (en) 1990-06-27 1990-08-15 Scient Generics Ltd Method of treatment and compositions therefor
US5137817A (en) 1990-10-05 1992-08-11 Amoco Corporation Apparatus and method for electroporation
US5279544A (en) 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
US5312456A (en) 1991-01-31 1994-05-17 Carnegie Mellon University Micromechanical barb and method for making the same
IT1244667B (it) 1991-03-28 1994-08-08 Enea Procedimento di microperforazione laser di cellule.
CA2066963A1 (en) 1991-05-15 1992-11-16 Norio Daikuzono Laser light irradiation apparatus
US5171215A (en) 1991-08-22 1992-12-15 Flanagan Dennis F Endermic method and apparatus
US5215520A (en) 1991-09-17 1993-06-01 Centre Internationale De Recherches Dermatologiques Galderma (C.I.R.D. Galderma) Method for delivering an active substance topically or percutaneously
JPH07508426A (ja) 1991-10-17 1995-09-21 サイエンティフィック ジェネリクス リミテッド 血液検体測定装置及びその方法
US5423803A (en) 1991-10-29 1995-06-13 Thermotrex Corporation Skin surface peeling process using laser
US5817089A (en) 1991-10-29 1998-10-06 Thermolase Corporation Skin treatment process using laser
US5752949A (en) 1991-10-29 1998-05-19 Thermolase Corporation Hair removal method
US5713845A (en) 1991-10-29 1998-02-03 Thermolase Corporation Laser assisted drug delivery
US5425728A (en) 1991-10-29 1995-06-20 Tankovich; Nicolai I. Hair removal device and method
US5226907A (en) 1991-10-29 1993-07-13 Tankovich Nikolai I Hair removal device and method
US6048337A (en) * 1992-01-07 2000-04-11 Principal Ab Transdermal perfusion of fluids
US5165418B1 (en) 1992-03-02 1999-12-14 Nikola I Tankovich Blood sampling device and method using a laser
US5223219A (en) 1992-04-10 1993-06-29 Biotrack, Inc. Analytical cartridge and system for detecting analytes in liquid samples
US5246437A (en) 1992-04-10 1993-09-21 Abela George S Cell treatment apparatus and method
NL9200731A (nl) 1992-04-22 1993-11-16 Jacob Korf Werkwijze en inrichting voor het niet-invasief bewaken van de concentratie van stoffen in bloed.
US5273525A (en) 1992-08-13 1993-12-28 Btx Inc. Injection and electroporation apparatus for drug and gene delivery
US5462520A (en) 1992-08-17 1995-10-31 Genetronics, Inc. Transsurface drug delivery by electrofusion of microbubbles to the tissue surface
US5318514A (en) 1992-08-17 1994-06-07 Btx, Inc. Applicator for the electroporation of drugs and genes into surface cells
JPH0670987A (ja) 1992-08-28 1994-03-15 Katsuro Tachibana 薬物投与・体液採取ユニット及び装置
US5421816A (en) 1992-10-14 1995-06-06 Endodermic Medical Technologies Company Ultrasonic transdermal drug delivery system
US5342355A (en) 1992-10-19 1994-08-30 Laser Centers Of America Energy delivering cap element for end of optic fiber conveying laser energy
US5643252A (en) 1992-10-28 1997-07-01 Venisect, Inc. Laser perforator
US5380272A (en) 1993-01-28 1995-01-10 Scientific Innovations Ltd. Transcutaneous drug delivery applicator
US5267985A (en) 1993-02-11 1993-12-07 Trancell, Inc. Drug delivery by multiple frequency phonophoresis
ATE233327T1 (de) * 1993-03-24 2003-03-15 Georgia Tech Res Inst Verfahren und vorrichtung zur verbrennungs cvd von filmen und beschichtungen
US5427585A (en) 1993-03-29 1995-06-27 Bettinger; David S. On-demand iontophoretic system
IE68890B1 (en) * 1993-04-08 1996-07-24 Elan Med Tech Intradermal delivery device
US5445609A (en) 1993-05-28 1995-08-29 Alza Corporation Electrotransport agent delivery device having a disposable component and a removable liner
PH31437A (en) * 1993-08-27 1998-11-03 Janssen Pharmaceutica Nv Tontophoretic delivery of an antimigrane drug.
US6056738A (en) 1997-01-31 2000-05-02 Transmedica International, Inc. Interstitial fluid monitoring
US5582184A (en) 1993-10-13 1996-12-10 Integ Incorporated Interstitial fluid collection and constituent measurement
US5458140A (en) 1993-11-15 1995-10-17 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers
US20020169394A1 (en) * 1993-11-15 2002-11-14 Eppstein Jonathan A. Integrated tissue poration, fluid harvesting and analysis device, and method therefor
US5885211A (en) 1993-11-15 1999-03-23 Spectrix, Inc. Microporation of human skin for monitoring the concentration of an analyte
US5445611A (en) 1993-12-08 1995-08-29 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal delivery with ultrasound and chemical enhancers
US5611806A (en) * 1994-05-23 1997-03-18 Samsung Electro-Mechanics Co., Ltd. Skin perforating device for transdermal medication
DE69519023T2 (de) 1994-06-24 2001-06-13 Cygnus, Inc. Einrichtung zur iontophoretischen probennahme
CA2131750C (en) 1994-07-26 2000-11-21 Thermolase Corporation Improved hair removal method
US6290991B1 (en) * 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
US5554153A (en) 1994-08-29 1996-09-10 Cell Robotics, Inc. Laser skin perforator
JPH10510175A (ja) 1994-12-09 1998-10-06 ノバルティス アクチェンゲゼルシャフト 経皮システム
WO1996037155A1 (en) 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical device and method for enhancing delivery of compounds through the skin
US5548140A (en) 1995-06-06 1996-08-20 Hughes Aircraft Company High-Speed, low-noise millimeterwave hemt and pseudomorphic hemt
AU725269B2 (en) 1995-07-25 2000-10-12 Massachusetts Institute Of Technology Enhanced transdermal transport using ultrasound
US5947921A (en) 1995-12-18 1999-09-07 Massachusetts Institute Of Technology Chemical and physical enhancers and ultrasound for transdermal drug delivery
ES2536459T3 (es) 1995-08-29 2015-05-25 Nitto Denko Corporation Microporación de piel humana para administración de fármacos y aplicaciones de supervisión
RU2209031C2 (ru) * 1995-10-30 2003-07-27 Элти Терапеутикс Корпорейшн Формирование микропор в коже человека для доставки лекарственных препаратов и мониторинга
US5801057A (en) 1996-03-22 1998-09-01 Smart; Wilson H. Microsampling device and method of construction
CA2253549C (en) * 1996-06-18 2005-10-25 Alza Corporation Device for enhancing transdermal agent delivery or sampling
US7070590B1 (en) * 1996-07-02 2006-07-04 Massachusetts Institute Of Technology Microchip drug delivery devices
ATE241405T1 (de) * 1996-07-03 2003-06-15 Altea Therapeutics Corp Mehrfache mechanische mikroperforierung von haut oder schleimhäuten
US5983136A (en) * 1996-09-17 1999-11-09 Deka Products Limited Partnership System for delivery of drugs by transport
JP2828064B2 (ja) 1996-09-20 1998-11-25 日本電気株式会社 吸引浸出液採取方法および装置
CA2272326C (en) * 1996-11-21 2005-03-29 Carole Rossi Miniature valve for filling the reservoir of an apparatus for the transdermal administration of medicine
US6093156A (en) 1996-12-06 2000-07-25 Abbott Laboratories Method and apparatus for obtaining blood for diagnostic tests
SE9604564D0 (sv) * 1996-12-12 1996-12-12 Paal Svedman Sätt och anordning vid avledning av elektriska strömmar
US6527716B1 (en) * 1997-12-30 2003-03-04 Altea Technologies, Inc. Microporation of tissue for delivery of bioactive agents
EP0952850A2 (en) 1996-12-31 1999-11-03 Altea Technologies, Inc. Microporation of tissue for delivery of bioactive agents
US5911703A (en) * 1997-05-22 1999-06-15 Avant Drug Delivery Systems, Inc. Two-stage fluid medicament jet injector
US6117290A (en) * 1997-09-26 2000-09-12 Pepex Biomedical, Llc System and method for measuring a bioanalyte such as lactate
DE69806963T2 (de) 1997-12-11 2002-11-21 Alza Corp., Mountain View Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses
CA2313698C (en) * 1997-12-11 2008-04-15 Alza Corporation Device for enhancing transdermal agent flux
EP1056396B1 (en) 1998-02-17 2005-11-09 Abbott Laboratories Interstitial fluid collection and monitoring device
ATE365050T1 (de) 1998-02-25 2007-07-15 Us Gov Sec Army Verwendung von hautpenetrationsförderern und für die zerstörung der oberen hautschichten geeigneten mitteln zur erhöhung der transkutanen immunantwort
US6022316A (en) * 1998-03-06 2000-02-08 Spectrx, Inc. Apparatus and method for electroporation of microporated tissue for enhancing flux rates for monitoring and delivery applications
US6173202B1 (en) * 1998-03-06 2001-01-09 Spectrx, Inc. Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue
EP1059882B1 (en) 1998-03-06 2007-10-17 SPECTRX, Inc. Integrated tissue poration, fluid harvesting and analysis device
EP1086214B1 (en) 1998-06-10 2009-11-25 Georgia Tech Research Corporation Microneedle devices and methods of their manufacture
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
DE69939906D1 (de) * 1998-07-14 2008-12-24 Altea Therapeutics Corp Transdermale transportvorrichtung zum kontrollierten entfernen von biologischen membranen durch pyrotechnische ladung
JP2002521077A (ja) 1998-07-21 2002-07-16 スペクトルクス,インコーポレイティド 連続式流体収集兼検出装置の液体管理システムおよび方法
WO2000004832A1 (en) 1998-07-21 2000-02-03 Spectrx, Inc. System and method for continuous analyte monitoring
WO2000015102A1 (en) 1998-09-10 2000-03-23 Spectrx, Inc. Attribute compensation for analyte detection and/or continuous monitoring
US7048723B1 (en) * 1998-09-18 2006-05-23 The University Of Utah Research Foundation Surface micromachined microneedles
US6148232A (en) 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction
US6708060B1 (en) 1998-11-09 2004-03-16 Transpharma Ltd. Handheld apparatus and method for transdermal drug delivery and analyte extraction
CA2376128C (en) * 1999-06-04 2009-01-06 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
DK1189660T3 (da) * 1999-06-08 2006-08-21 Altea Therapeutics Corp Apparat til mikroperforering af biologiske membraner ved hjælp af tyndfilms-vævsgrænseflade-anordninger samt fremgangsmåde til fremstilling deraf
US6312612B1 (en) * 1999-06-09 2001-11-06 The Procter & Gamble Company Apparatus and method for manufacturing an intracutaneous microneedle array
US20030078499A1 (en) * 1999-08-12 2003-04-24 Eppstein Jonathan A. Microporation of tissue for delivery of bioactive agents
US7113821B1 (en) 1999-08-25 2006-09-26 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery
US7133717B2 (en) * 1999-08-25 2006-11-07 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery and diagnostic sampling
US6251083B1 (en) * 1999-09-07 2001-06-26 Amira Medical Interstitial fluid methods and devices for determination of an analyte in the body
CA2390893C (en) * 1999-11-19 2010-10-05 Spectrx, Inc. Tissue interface device
US6659982B2 (en) 2000-05-08 2003-12-09 Sterling Medivations, Inc. Micro infusion drug delivery device
CA2843053C (en) 2000-06-01 2015-08-25 Georgetown University Systems and methods for monitoring health and delivering drugs transdermally
US7141034B2 (en) * 2000-06-08 2006-11-28 Altea Therapeutics Corporation Transdermal drug delivery device, method of making same and method of using same
US7108681B2 (en) * 2000-10-16 2006-09-19 Corium International, Inc. Microstructures for delivering a composition cutaneously to skin
US7131987B2 (en) * 2000-10-16 2006-11-07 Corium International, Inc. Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation
US20020131994A1 (en) 2001-01-10 2002-09-19 Schur Henry B. Non-irritating formulation for the transdermal delivery of substances
US20020099356A1 (en) * 2001-01-19 2002-07-25 Unger Evan C. Transmembrane transport apparatus and method
US6906540B2 (en) * 2001-09-20 2005-06-14 Wentworth Laboratories, Inc. Method for chemically etching photo-defined micro electrical contacts
EP1450876B1 (en) 2001-11-07 2016-08-17 Syneron Medical Ltd. Integrated transdermal drug delivery system
US8016811B2 (en) * 2003-10-24 2011-09-13 Altea Therapeutics Corporation Method for transdermal delivery of permeant substances
US20080274166A1 (en) 2005-06-10 2008-11-06 Transpharma Medical Ltd. Patch for Transdermal Drug Delivery
TWI419717B (zh) * 2005-06-17 2013-12-21 Altea Therapeutics Corp 滲透傳送系統及其使用方法

Also Published As

Publication number Publication date
RU2014125534A (ru) 2015-12-27
US20050090800A1 (en) 2005-04-28
IL175088A0 (en) 2006-08-20
CN1893998A (zh) 2007-01-10
AU2004284914B2 (en) 2011-01-27
WO2005042051A3 (en) 2006-04-20
US9033950B2 (en) 2015-05-19
RU2366467C2 (ru) 2009-09-10
EP2314282A2 (en) 2011-04-27
CA2543534A1 (en) 2005-05-12
US8016811B2 (en) 2011-09-13
KR20060102555A (ko) 2006-09-27
EP1689483A4 (en) 2007-09-12
JP2007508904A (ja) 2007-04-12
US20200023173A1 (en) 2020-01-23
US20150265823A1 (en) 2015-09-24
WO2005042051A2 (en) 2005-05-12
EP2314282A3 (en) 2011-08-03
KR101232225B1 (ko) 2013-02-12
CA2543534C (en) 2014-03-18
RU2009122870A (ru) 2010-12-20
AU2004284914A1 (en) 2005-05-12
JP5032121B2 (ja) 2012-09-26
US20120101426A1 (en) 2012-04-26
RU2006117783A (ru) 2007-12-10
RU2531923C2 (ru) 2014-10-27
EP1689483A2 (en) 2006-08-16
RU2691310C2 (ru) 2019-06-11

Similar Documents

Publication Publication Date Title
NO20062342L (no) Metode for transdermal levering av permeante substanser
BR0312671A (pt) Dispositivo de microagulhas, método para utilizar um dispositivo de microagulhas, e, método para aplicar um dispositivo de microagulhas
WO2008127373A3 (en) Methods and devices for treating tissue
SE0301676D0 (sv) Elastomerbildande barriär-preparat
SG130190A1 (en) Method and device for enhancing transdermal agent flux
WO2007089508A3 (en) Medical tools for facilitating deep lamellar endothelial keratoplasty and related methods
ATE440623T1 (de) Biologisch absorbierbare überzüge für implantierbare vorrichtungen
WO2007050546A3 (en) Devices and methods for treating mitral valve regurgitation
WO2003026733A3 (en) Microneedle with membrane
AU2002213168A1 (en) Microstructures for delivering a composition cutaneously to skin
ATE464863T1 (de) Implantierbares medizinprodukt zur selektiven modulation der abgabe von mitteln in situ
DE60139077D1 (de) System zur endotrachealen/ösophagischen stimulation vor und während eines medizinischen verfahrens
CA2376368A1 (en) Apparatus for microporation of biological membranes using thin film tissue interface devices, and method therefor
WO2005034763A8 (en) Devices, systems, and methods for suturing tissue
AR046307A1 (es) Metodo de pretratamiento y sistema para mejorar la administracion transdermica de drogas
MXPA02009275A (es) Metodo para preparar dispersiones de alta presion/alto esfuerzo cortante que contienen ingredientes fisiologicamente activos.
WO2007041434A3 (en) Iontophoresis apparatus and method for delivery of angiogenic factors to enhance healing of injured tissue
AU2002364139A1 (en) Apparatus and method for performing spinal surgery
WO2004032963A3 (en) Photokinetic delivery of biologically active substances using pulsed incoherent light
WO2008005873A3 (en) Methods, systems and apparatus for relieving pressure in an organ
DE69533436D1 (de) System zum einbringen von material in die korneale stroma
NO20071333L (no) Vevforsterket separator og kontinuerlig metode for a produsere det samme.
NO20074100L (no) Mikroimplantater for okulaer administrering
ATE415817T1 (de) Agrochemische formulierungen
ATE553790T1 (de) Material zur implantation

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application