ATE241405T1 - Mehrfache mechanische mikroperforierung von haut oder schleimhäuten - Google Patents

Mehrfache mechanische mikroperforierung von haut oder schleimhäuten

Info

Publication number
ATE241405T1
ATE241405T1 AT97936041T AT97936041T ATE241405T1 AT E241405 T1 ATE241405 T1 AT E241405T1 AT 97936041 T AT97936041 T AT 97936041T AT 97936041 T AT97936041 T AT 97936041T AT E241405 T1 ATE241405 T1 AT E241405T1
Authority
AT
Austria
Prior art keywords
skin
permeant
measures
microperforation
mucous
Prior art date
Application number
AT97936041T
Other languages
English (en)
Inventor
Jonathan A Eppstein
Original Assignee
Altea Therapeutics Corp
Spectrx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altea Therapeutics Corp, Spectrx Inc filed Critical Altea Therapeutics Corp
Application granted granted Critical
Publication of ATE241405T1 publication Critical patent/ATE241405T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0038—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
AT97936041T 1996-07-03 1997-07-03 Mehrfache mechanische mikroperforierung von haut oder schleimhäuten ATE241405T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2121296P 1996-07-03 1996-07-03
PCT/US1997/011670 WO1998000193A1 (en) 1996-07-03 1997-07-03 Multiple mechanical microporation of skin or mucosa

Publications (1)

Publication Number Publication Date
ATE241405T1 true ATE241405T1 (de) 2003-06-15

Family

ID=21802981

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97936041T ATE241405T1 (de) 1996-07-03 1997-07-03 Mehrfache mechanische mikroperforierung von haut oder schleimhäuten

Country Status (10)

Country Link
US (2) US6183434B1 (de)
EP (1) EP0921840B1 (de)
JP (1) JP3942640B2 (de)
AT (1) ATE241405T1 (de)
AU (1) AU3880697A (de)
CA (1) CA2259437C (de)
DE (1) DE69722414T2 (de)
DK (1) DK0921840T3 (de)
ES (1) ES2200187T3 (de)
WO (1) WO1998000193A1 (de)

Families Citing this family (321)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060240381A1 (en) * 1995-08-31 2006-10-26 Biolase Technology, Inc. Fluid conditioning system
US20090143775A1 (en) * 1995-08-31 2009-06-04 Rizoiu Ioana M Medical laser having controlled-temperature and sterilized fluid output
US7828749B2 (en) * 1996-05-17 2010-11-09 Roche Diagnostics Operations, Inc. Blood and interstitial fluid sampling device
US7235056B2 (en) * 1996-05-17 2007-06-26 Amira Medical Body fluid sampling device and methods of use
US20020010406A1 (en) 1996-05-17 2002-01-24 Douglas Joel S. Methods and apparatus for expressing body fluid from an incision
EP1579814A3 (de) 1996-05-17 2006-06-14 Roche Diagnostics Operations, Inc. Verfahren und Vorrichtung zur Probenahme und Analyse von Körperflüssigkeit
US6230051B1 (en) * 1996-06-18 2001-05-08 Alza Corporation Device for enhancing transdermal agent delivery or sampling
ATE231015T1 (de) * 1996-09-17 2003-02-15 Deka Products Lp System zur medikamentenabgabe durch transport
US5980898A (en) * 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
US20060002949A1 (en) 1996-11-14 2006-01-05 Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. Transcutaneous immunization without heterologous adjuvant
US20060002959A1 (en) * 1996-11-14 2006-01-05 Government Of The United States Skin-sctive adjuvants for transcutaneous immuization
US6797276B1 (en) 1996-11-14 2004-09-28 The United States Of America As Represented By The Secretary Of The Army Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response
US8182473B2 (en) * 1999-01-08 2012-05-22 Palomar Medical Technologies Cooling system for a photocosmetic device
US6517532B1 (en) 1997-05-15 2003-02-11 Palomar Medical Technologies, Inc. Light energy delivery head
US20060149343A1 (en) * 1996-12-02 2006-07-06 Palomar Medical Technologies, Inc. Cooling system for a photocosmetic device
US7204832B2 (en) 1996-12-02 2007-04-17 Pálomar Medical Technologies, Inc. Cooling system for a photo cosmetic device
US6527716B1 (en) 1997-12-30 2003-03-04 Altea Technologies, Inc. Microporation of tissue for delivery of bioactive agents
WO1998029134A2 (en) * 1996-12-31 1998-07-09 Altea Technologies, Inc. Microporation of tissue for delivery of bioactive agents
DK0991372T3 (da) 1997-05-15 2004-12-06 Palomar Medical Tech Inc Apparat til dermatologisk behandling
US20040258703A1 (en) * 1997-11-14 2004-12-23 The Government Of The Us, As Represented By The Secretary Of The Army Skin-active adjuvants for transcutaneous immunization
US6706000B2 (en) * 1997-11-21 2004-03-16 Amira Medical Methods and apparatus for expressing body fluid from an incision
DE19800416C2 (de) * 1998-01-08 2002-09-19 Storz Karl Gmbh & Co Kg Vorrichtung zur Behandlung von Körpergewebe, insbesondere von oberflächennahem Weichgewebe, mittels Ultraschall
JP5314231B2 (ja) * 1998-03-06 2013-10-16 スペクトリクス，インコーポレイテッド 生物医学的適用のための光熱的構造物
US6173202B1 (en) * 1998-03-06 2001-01-09 Spectrx, Inc. Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue
WO1999046005A1 (en) 1998-03-12 1999-09-16 Palomar Medical Technologies, Inc. System for electromagnetic radiation of the skin
EP1086214B1 (de) * 1998-06-10 2009-11-25 Georgia Tech Research Corporation Mikronadel-einrichtungen und verfahren zur deren herstellung
US7344499B1 (en) 1998-06-10 2008-03-18 Georgia Tech Research Corporation Microneedle device for extraction and sensing of bodily fluids
US6503231B1 (en) 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
JP2002519641A (ja) 1998-06-24 2002-07-02 トランスダーム ダイアグノスティックス， インコーポレイテッド 分析物の非侵襲性経皮検出
EP1189281B1 (de) * 1998-06-30 2007-08-22 Micronas GmbH Chip-Anordnung
WO2000003758A1 (en) 1998-07-14 2000-01-27 Spectrx, Inc. Controlled removal of biological membrane by pyrotechnic charge for transmembrane transport
US7384396B2 (en) 1998-07-21 2008-06-10 Spectrx Inc. System and method for continuous analyte monitoring
US7037277B1 (en) 1998-07-21 2006-05-02 Spectrx, Inc. System and method for fluid management in a continuous fluid collection and sensor device
CA2343762A1 (en) 1998-09-10 2000-03-23 Spectrx, Inc. Attribute compensation for analyte detection and/or continuous monitoring
US6148232A (en) 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction
US6597946B2 (en) * 1998-11-09 2003-07-22 Transpharma Ltd. Electronic card for transdermal drug delivery and analyte extraction
US6708060B1 (en) * 1998-11-09 2004-03-16 Transpharma Ltd. Handheld apparatus and method for transdermal drug delivery and analyte extraction
US6611706B2 (en) 1998-11-09 2003-08-26 Transpharma Ltd. Monopolar and bipolar current application for transdermal drug delivery and analyte extraction
JP4932086B2 (ja) * 1999-04-08 2012-05-16 インターセル ユーエスエイ、インコーポレイテッド 経皮的免疫のための乾燥製剤
WO2000074763A2 (en) * 1999-06-04 2000-12-14 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6743211B1 (en) 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6611707B1 (en) 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
EP2286868A3 (de) * 1999-06-08 2012-05-16 Altea Therapeutics Corporation Vorrichtung zum Erzeugen von Mikroporen in biologischen Membranen mittels Dünnfilm-Gewebeschnittstelle und Herstellungsverfahren
US6256533B1 (en) 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6312612B1 (en) 1999-06-09 2001-11-06 The Procter & Gamble Company Apparatus and method for manufacturing an intracutaneous microneedle array
US6379324B1 (en) 1999-06-09 2002-04-30 The Procter & Gamble Company Intracutaneous microneedle array apparatus
CA2376952A1 (en) 1999-06-11 2000-12-21 Mark A. Samuels Alignment devices and methods for fluid extraction from tissue and substance delivery
US6925317B1 (en) 1999-06-11 2005-08-02 Spectrx, Inc. Integrated alignment devices, system, and methods for efficient fluid extraction, substance delivery and other applications
CA2371888A1 (en) * 1999-06-18 2000-12-28 University Of Virginia An apparatus for fluid transport and related method thereof
US20030078499A1 (en) * 1999-08-12 2003-04-24 Eppstein Jonathan A. Microporation of tissue for delivery of bioactive agents
US6623457B1 (en) 1999-09-22 2003-09-23 Becton, Dickinson And Company Method and apparatus for the transdermal administration of a substance
US6835184B1 (en) * 1999-09-24 2004-12-28 Becton, Dickinson And Company Method and device for abrading skin
WO2001041863A1 (en) 1999-12-10 2001-06-14 Alza Corporation Device and method for enhancing microprotrusion skin piercing
CA2398238A1 (en) * 2000-01-25 2001-08-02 Palomar Medical Technologies, Inc. Method and apparatus for medical treatment utilizing long duration electromagnetic radiation
EP1276426A4 (de) * 2000-03-09 2008-03-19 Nanopass Ltd Systeme und verfahren zum transportieren von flüssigkeiten durch biologische barrieren und produktionstechniken für solche systeme
US6595947B1 (en) 2000-05-22 2003-07-22 Becton, Dickinson And Company Topical delivery of vaccines
US6565532B1 (en) 2000-07-12 2003-05-20 The Procter & Gamble Company Microneedle apparatus used for marking skin and for dispensing semi-permanent subcutaneous makeup
US6540675B2 (en) 2000-06-27 2003-04-01 Rosedale Medical, Inc. Analyte monitor
US6440096B1 (en) * 2000-07-14 2002-08-27 Becton, Dickinson And Co. Microdevice and method of manufacturing a microdevice
ATE367805T1 (de) 2000-09-08 2007-08-15 Alza Corp Transdermale vorrichtung
ATE363922T1 (de) * 2000-09-08 2007-06-15 Insulet Corp Infusionsvorrichtung und system
JP2002085561A (ja) * 2000-09-14 2002-03-26 Terumo Corp 液体注入針
AU2002210881A1 (en) * 2000-10-12 2002-04-22 Ink Jet Technology Ltd. Transdermal method
US6882884B1 (en) 2000-10-13 2005-04-19 Soundskin, L.L.C. Process for the stimulation of production of extracellular dermal proteins in human tissue
NZ525295A (en) 2000-10-13 2005-05-27 Alza Corp Microprotrusion member retainer for impact applicator
US7419481B2 (en) 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
ES2324461T3 (es) 2000-10-13 2009-08-07 Alza Corporation Aparato y procedimiento para perforar la piel con microprotuberancias.
CN100391404C (zh) 2000-10-13 2008-06-04 阿尔扎公司 微刀片阵列的冲击式敷贴器
US7131987B2 (en) 2000-10-16 2006-11-07 Corium International, Inc. Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
US6821281B2 (en) 2000-10-16 2004-11-23 The Procter & Gamble Company Microstructures for treating and conditioning skin
ATE428466T1 (de) 2000-10-26 2009-05-15 Alza Corp Transdermales arzneistoffverabreichungssytem mit beschichteten mikrovorsprüngen
US9302903B2 (en) 2000-12-14 2016-04-05 Georgia Tech Research Corporation Microneedle devices and production thereof
WO2002050584A2 (en) 2000-12-21 2002-06-27 Biovalve Technologies, Inc. Microneedle array systems
US20080183162A1 (en) * 2000-12-28 2008-07-31 Palomar Medical Technologies, Inc. Methods And Devices For Fractional Ablation Of Tissue
EP1372708B1 (de) 2001-02-13 2008-06-18 GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE ARMY Impstoffe zur transkutanen immunisierung gegen reisediarrhö
US6805926B2 (en) 2001-02-23 2004-10-19 Technical Graphics Security Products, Llc Security label having security element and method of making same
US6888319B2 (en) * 2001-03-01 2005-05-03 Palomar Medical Technologies, Inc. Flashlamp drive circuit
EP1365699A2 (de) * 2001-03-02 2003-12-03 Palomar Medical Technologies, Inc. Vorrichtung und verfahren zur fotokosmetischen und fotodermatologischen behandlung
US6663820B2 (en) 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
WO2002074173A1 (en) 2001-03-16 2002-09-26 Alza Corporation Method and apparatus for coating skin piercing microprojections
KR20040020889A (ko) 2001-04-20 2004-03-09 알자 코포레이션 유용한 약물을 갖는 코팅을 포함하는 미세돌출부 어레이
EP3251722B1 (de) 2001-04-20 2020-06-17 ALZA Corporation Mikroprojektionsanordnung mit einer beschichtung, der ein vorteilhaftes mittel enthält und beschichtungsverfahren dafuer
US6591124B2 (en) 2001-05-11 2003-07-08 The Procter & Gamble Company Portable interstitial fluid monitoring system
US6855117B2 (en) 2001-08-01 2005-02-15 Johnson & Johnson Consumer Companies, Inc. Method of treating the skin of a subject
US6790179B2 (en) 2001-08-01 2004-09-14 Johnson & Johnson Consumer Companies, Inc. Method of examining and diagnosing skin health
US6840910B2 (en) 2001-08-01 2005-01-11 Johnson & Johnson Consumer Companies, Inc. Method of distributing skin care products
ATE336276T1 (de) * 2001-06-08 2006-09-15 Becton Dickinson Co Vorrichtung zur manipulation von nadeln oder polierarray
US20020188223A1 (en) * 2001-06-08 2002-12-12 Edward Perez Devices and methods for the expression of bodily fluids from an incision
US6721586B2 (en) 2001-06-12 2004-04-13 Lifescan, Inc. Percutaneous biological fluid sampling and analyte measurement devices and methods
US6793632B2 (en) 2001-06-12 2004-09-21 Lifescan, Inc. Percutaneous biological fluid constituent sampling and measurement devices and methods
US6875613B2 (en) 2001-06-12 2005-04-05 Lifescan, Inc. Biological fluid constituent sampling and measurement devices and methods
US6837988B2 (en) 2001-06-12 2005-01-04 Lifescan, Inc. Biological fluid sampling and analyte measurement devices and methods
US6501976B1 (en) 2001-06-12 2002-12-31 Lifescan, Inc. Percutaneous biological fluid sampling and analyte measurement devices and methods
US20030028125A1 (en) * 2001-08-06 2003-02-06 Yuzhakov Vadim V. Physiological sample collection devices and methods of using the same
US6881203B2 (en) * 2001-09-05 2005-04-19 3M Innovative Properties Company Microneedle arrays and methods of manufacturing the same
US20040087992A1 (en) * 2002-08-09 2004-05-06 Vladimir Gartstein Microstructures for delivering a composition cutaneously to skin using rotatable structures
EP1425064A2 (de) * 2001-09-14 2004-06-09 The Procter & Gamble Company Mikrostrukturen für die kutane verabreichung einer komposition mit hilfe von rollen elementen
WO2003024507A2 (en) 2001-09-19 2003-03-27 Biovalve Technologies, Inc. Microneedles, microneedle arrays, and systems and methods relating to same
US8920375B2 (en) 2001-09-21 2014-12-30 Valeritas, Inc. Gas pressure actuated microneedle arrays, and systems and methods relating to same
US7429258B2 (en) * 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US20040120964A1 (en) * 2001-10-29 2004-06-24 Mikszta John A. Needleless vaccination using chimeric yellow fever vaccine-vectored vaccines against heterologous flaviviruses
MXPA04003953A (es) * 2001-10-29 2004-06-18 Becton Dickinson Co Metodo y dispositivo para la entrega de una sustancia.
US20040147984A1 (en) * 2001-11-29 2004-07-29 Palomar Medical Technologies, Inc. Methods and apparatus for delivering low power optical treatments
US6952604B2 (en) * 2001-12-21 2005-10-04 Becton, Dickinson And Company Minimally-invasive system and method for monitoring analyte levels
AU2002367397A1 (en) * 2001-12-27 2003-07-24 Palomar Medical Technologies, Inc. Method and apparatus for improved vascular related treatment
US20040073175A1 (en) * 2002-01-07 2004-04-15 Jacobson James D. Infusion system
US6908453B2 (en) * 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
EP2111885B1 (de) 2002-02-04 2011-09-21 Becton, Dickinson and Company Vorrichtung und Verfahren zur Versorgung oder Entziehung einer Substanz durch die Haut
US7004928B2 (en) 2002-02-08 2006-02-28 Rosedale Medical, Inc. Autonomous, ambulatory analyte monitor or drug delivery device
US9918665B2 (en) 2002-03-11 2018-03-20 Nitto Denko Corporation Transdermal porator and patch system and method for using same
WO2003077971A2 (en) 2002-03-11 2003-09-25 Altea Therapeutics Corporation Transdermal drug delivery patch system, method of making same and method of using same
US8116860B2 (en) * 2002-03-11 2012-02-14 Altea Therapeutics Corporation Transdermal porator and patch system and method for using same
WO2003089043A2 (en) * 2002-04-19 2003-10-30 Transpharma Medical Ltd. Handheld transdermal drug delivery and analyte extraction
US6960192B1 (en) 2002-04-23 2005-11-01 Insulet Corporation Transcutaneous fluid delivery system
US7060192B2 (en) 2002-05-09 2006-06-13 Lifescan, Inc. Methods of fabricating physiological sample collection devices
US20070213696A1 (en) * 2006-03-10 2007-09-13 Palomar Medical Technologies, Inc. Photocosmetic device
EP1523283A1 (de) * 2002-06-19 2005-04-20 Palomar Medical Technologies, Inc. Verfahren und vorrichtung zur photothermischen tiefenbehandlung des gewebes
AU2003245573A1 (en) 2002-06-19 2004-01-06 Palomar Medical Technologies, Inc. Method and apparatus for treatment of cutaneous and subcutaneous conditions
US7018360B2 (en) 2002-07-16 2006-03-28 Insulet Corporation Flow restriction system and method for patient infusion device
CN102872526A (zh) * 2002-07-19 2013-01-16 3M创新有限公司 微针装置和微针施用设备
AU2003268206B2 (en) * 2002-08-29 2008-12-18 Becton, Dickinson And Company Microprotrusion arrays and methods for using same to deliver substances into tissue
US7128727B2 (en) 2002-09-30 2006-10-31 Flaherty J Christopher Components and methods for patient infusion device
US7144384B2 (en) 2002-09-30 2006-12-05 Insulet Corporation Dispenser components and methods for patient infusion device
US20070219604A1 (en) * 2006-03-20 2007-09-20 Palomar Medical Technologies, Inc. Treatment of tissue with radiant energy
EP1590034B1 (de) * 2002-10-07 2014-05-14 Biovalve Technologies, Inc. Pflaster mit mikronadelanordnung
EP2522293A2 (de) * 2002-10-23 2012-11-14 Palomar Medical Technologies, Inc. Photobehandlungsvorrichtung zur Verwendung mit Kühlmitteln und topischen Substanzen
US20040225339A1 (en) * 2002-12-20 2004-11-11 Palomar Medical Technologies Inc. Light treatments for acne and other disorders of follicles
WO2004073537A2 (en) * 2003-02-19 2004-09-02 Palomar Medical Technologies, Inc. Method and apparatus for treating pseudofolliculitis barbae
US7578954B2 (en) 2003-02-24 2009-08-25 Corium International, Inc. Method for manufacturing microstructures having multiple microelements with through-holes
US7052652B2 (en) 2003-03-24 2006-05-30 Rosedale Medical, Inc. Analyte concentration detection devices and methods
US20080149524A1 (en) * 2003-03-27 2008-06-26 Rademaker William B Food containers including dental cleaning devices and other personal care items
EP3572106A1 (de) * 2003-04-23 2019-11-27 Valeritas, Inc. Hydraulisch aktivierte pumpe für langzeitabgabe von medikamenten
JP2004343275A (ja) * 2003-05-14 2004-12-02 Murata Mach Ltd 画像処理システム及びスキャナ装置
AU2004255218A1 (en) 2003-06-30 2005-01-20 Alza Corporation Formulations for coated microprojections containing non-volatile counterions
US20050059166A1 (en) * 2003-09-11 2005-03-17 Robert Markes Sampling instrument
US8016811B2 (en) 2003-10-24 2011-09-13 Altea Therapeutics Corporation Method for transdermal delivery of permeant substances
CA2543086A1 (en) 2003-10-24 2005-05-12 Alza Corporation Pretreatment method and system for enhancing transdermal drug delivery
CA2543154A1 (en) 2003-10-28 2005-05-19 Alza Corporation Method and apparatus for reducing the incidence of tobacco use
CN100571643C (zh) 2003-10-31 2009-12-23 阿尔扎公司 用于微凸起阵列的自驱动施加器
CN1905842A (zh) * 2003-11-21 2007-01-31 阿尔扎公司 超声促进疫苗透皮释放的方法和系统
CN1886171A (zh) * 2003-11-28 2006-12-27 艾克若克斯Dds有限公司 快速经皮施用的方法和系统
US7309335B2 (en) * 2003-12-31 2007-12-18 Palomar Medical Technologies, Inc. Dermatological treatment with visualization
US20100151406A1 (en) 2004-01-08 2010-06-17 Dmitri Boutoussov Fluid conditioning system
CN1946452A (zh) * 2004-01-09 2007-04-11 阿尔扎公司 频率促进的药物透皮释放方法和系统
DK1722670T3 (da) 2004-03-06 2014-01-06 Hoffmann La Roche Kropsfluidum-prøveudtagningsapparat
US7819822B2 (en) * 2004-03-06 2010-10-26 Roche Diagnostics Operations, Inc. Body fluid sampling device
EP1737357B1 (de) * 2004-03-24 2019-12-11 Corium, Inc. Vorrichtung zur transdermalen abgabe
WO2005096979A1 (en) 2004-04-01 2005-10-20 The General Hospital Corporation Method and apparatus for dermatological treatment and tissue reshaping
WO2005099369A2 (en) * 2004-04-09 2005-10-27 Palomar Medical Technologies, Inc. Emr treated islets
JP4981660B2 (ja) * 2004-04-12 2012-07-25 アラーガン、インコーポレイテッド マルチサイト注射システム
EP1744683B1 (de) 2004-05-13 2016-03-16 Alza Corporation Gerät und verfahren für die transdermale abgabe von parathyroidhormon-mitteln
US7315758B2 (en) 2004-06-03 2008-01-01 Lynntech, Inc. Transdermal delivery of therapeutic agent
WO2006014425A1 (en) * 2004-07-02 2006-02-09 Biovalve Technologies, Inc. Methods and devices for delivering glp-1 and uses thereof
US7896819B2 (en) * 2004-10-21 2011-03-01 Rebec Mihailo V Method of determining the concentration of an analyte in a body fluid and system in therefor
US20060253176A1 (en) * 2005-02-18 2006-11-09 Palomar Medical Technologies, Inc. Dermatological treatment device with deflector optic
WO2006089227A2 (en) * 2005-02-18 2006-08-24 Palomar Medical Technologies, Inc. Dermatological treatment device
US7856985B2 (en) 2005-04-22 2010-12-28 Cynosure, Inc. Method of treatment body tissue using a non-uniform laser beam
US7751895B2 (en) * 2005-06-03 2010-07-06 Biolase Technology, Inc. Tissue treatment device and method
CA2610757A1 (en) * 2005-06-10 2006-12-14 Transpharma Medical, Ltd. Patch for transdermal drug delivery
US20060281187A1 (en) * 2005-06-13 2006-12-14 Rosedale Medical, Inc. Analyte detection devices and methods with hematocrit/volume correction and feedback control
TWI419717B (zh) * 2005-06-17 2013-12-21 Altea Therapeutics Corp 滲透傳送系統及其使用方法
KR20110074936A (ko) * 2005-06-24 2011-07-04 바이오레이즈 테크놀로지, 인크. 전자기 에너지 출력 장치
WO2007035444A2 (en) 2005-09-15 2007-03-29 Palomar Medical Technologies, Inc. Skin optical characterization device
US8801631B2 (en) 2005-09-30 2014-08-12 Intuity Medical, Inc. Devices and methods for facilitating fluid transport
CA2624059C (en) * 2005-09-30 2019-04-02 Intuity Medical, Inc. Multi-site body fluid sampling and analysis cartridge
US20070194717A1 (en) * 2006-02-17 2007-08-23 Palomar Medical Technologies, Inc. Lamp for use in a tissue treatment device
CN103239773B (zh) 2006-03-30 2015-08-26 瓦莱里塔斯公司 多筒式流体递送器械
US20070255355A1 (en) * 2006-04-06 2007-11-01 Palomar Medical Technologies, Inc. Apparatus and method for skin treatment with compression and decompression
US7662177B2 (en) * 2006-04-12 2010-02-16 Bacoustics, Llc Apparatus and methods for pain relief using ultrasound waves in combination with cryogenic energy
US20080234626A1 (en) * 2006-04-26 2008-09-25 Chelak Todd M Multi-stage microporation device
JP4265696B2 (ja) * 2006-07-04 2009-05-20 凸版印刷株式会社 マイクロニードルの製造方法
CN101528830A (zh) 2006-07-10 2009-09-09 麦德医像公司 超弹性环氧水凝胶
EP2789363B1 (de) 2006-07-27 2016-11-02 Toppan Printing Co., Ltd. Verfahren zur Herstellung einer Mikronadel
US7586957B2 (en) 2006-08-02 2009-09-08 Cynosure, Inc Picosecond laser apparatus and methods for its operation and use
US20080152592A1 (en) * 2006-12-21 2008-06-26 Bayer Healthcare Llc Method of therapeutic drug monitoring
WO2008091602A2 (en) * 2007-01-22 2008-07-31 Corium International, Inc. Applicators for microneedle arrays
US9101377B2 (en) * 2007-01-25 2015-08-11 Biolase, Inc. Electromagnetic energy output system
US7695469B2 (en) * 2007-01-25 2010-04-13 Biolase Technology, Inc. Electromagnetic energy output system
US7815630B2 (en) * 2007-01-25 2010-10-19 Biolase Technology, Inc. Target-close electromagnetic energy emitting device
US20080186591A1 (en) * 2007-02-01 2008-08-07 Palomar Medical Technologies, Inc. Dermatological device having a zoom lens system
EP2146689B1 (de) 2007-04-16 2020-08-12 Corium, Inc. Einen wirkstoff enthaltende lösungsmittel-gegossene mikronadelanordnungen
US8911749B2 (en) * 2007-04-16 2014-12-16 Corium International, Inc. Vaccine delivery via microneedle arrays
US20090225060A1 (en) * 2007-05-03 2009-09-10 Rizoiu Ioana M Wrist-mounted laser with animated, page-based graphical user-interface
US8417311B2 (en) 2008-09-12 2013-04-09 Optiscan Biomedical Corporation Fluid component analysis system and method for glucose monitoring and control
US8143034B2 (en) * 2007-08-21 2012-03-27 Polytechnic Institute Of New York University Method for preparing long-chain hydroxyacids, diacids and oligomers and polymers thereof
US20090053673A1 (en) * 2007-08-23 2009-02-26 Zimmer, Inc. Method for localized treatment of periodontal tissue
WO2009047774A2 (en) * 2007-10-09 2009-04-16 Transpharma Ltd. Magnetic patch coupling
JP5587782B2 (ja) 2007-10-10 2014-09-10 オプテイスカン・バイオメデイカル・コーポレーシヨン グルコースのモニターおよび調節のための流体成分分析システムおよび方法
JP5178132B2 (ja) * 2007-10-11 2013-04-10 キヤノン株式会社 画像処理システム並びに画像処理方法
WO2009050718A2 (en) * 2007-10-17 2009-04-23 Transpharma Medical Ltd. Dissolution rate verification
CA2704164A1 (en) * 2007-10-29 2009-05-07 Transpharma Medical Ltd. Vertical patch drying
WO2009073734A2 (en) 2007-12-03 2009-06-11 Medipacs, Inc. Fluid metering device
AU2008332738B2 (en) 2007-12-05 2013-08-15 Syneron Medical Ltd. A disposable electromagnetic energy applicator and method of using it
WO2009079589A2 (en) 2007-12-17 2009-06-25 New World Pharmaceuticals, Llc Integrated intra-dermal delivery, diagnostic and communication system
US8700122B2 (en) * 2008-05-02 2014-04-15 Covidien Lp Skin preparation device and biopotential sensor
WO2009145920A1 (en) * 2008-05-30 2009-12-03 Intuity Medical, Inc. Body fluid sampling device -- sampling site interface
JP5642066B2 (ja) 2008-06-06 2014-12-17 インテュイティ メディカル インコーポレイテッド 体液の試料内に含まれている検体の存在または濃度を決定する検定を行う方法および装置
DK3639744T3 (da) 2008-06-06 2022-02-21 Intuity Medical Inc Blodglukosemåler og fremgangsmåde til anvendelse
GB0811856D0 (en) * 2008-06-27 2008-07-30 Ucl Business Plc Magnetic microbubbles, methods of preparing them and their uses
KR101013581B1 (ko) * 2008-08-06 2011-02-14 라종주 전기 피부 미용기
US7959598B2 (en) 2008-08-20 2011-06-14 Asante Solutions, Inc. Infusion pump systems and methods
EP3187219B2 (de) 2008-12-02 2026-03-04 Allergan, Inc. Injektionsvorrichtung
TW201027393A (en) 2009-01-06 2010-07-16 Pixart Imaging Inc Electronic apparatus with virtual data input device
US8606366B2 (en) 2009-02-18 2013-12-10 Syneron Medical Ltd. Skin treatment apparatus for personal use and method for using same
ES2634667T3 (es) * 2009-04-24 2017-09-28 Corium International, Inc. Métodos para fabricar conjuntos de microproyección
US9919168B2 (en) 2009-07-23 2018-03-20 Palomar Medical Technologies, Inc. Method for improvement of cellulite appearance
WO2011032011A1 (en) 2009-09-10 2011-03-17 Medipacs, Inc. Low profile actuator and improved method of caregiver controlled administration of therapeutics
US9014799B2 (en) * 2009-10-08 2015-04-21 Palo Alto Research Center Incorporated Transmucosal drug delivery device and method including electrically-actuated permeation enhancement
US8882748B2 (en) * 2009-10-08 2014-11-11 Palo Alto Research Center Incorporated Transmucosal drug delivery device and method including chemical permeation enhancers
US9017310B2 (en) * 2009-10-08 2015-04-28 Palo Alto Research Center Incorporated Transmucosal drug delivery device and method including microneedles
WO2011065981A1 (en) 2009-11-30 2011-06-03 Intuity Medical, Inc. Calibration material delivery devices and methods
US20110172645A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Wearable drug delivery device including integrated pumping and activation elements
US20110172639A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Device and method for delivery of microneedle to desired depth within the skin
US20110172637A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including tissue support structure
US20110172609A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Microneedle component assembly for drug delivery device
US9500186B2 (en) 2010-02-01 2016-11-22 Medipacs, Inc. High surface area polymer actuator with gas mitigating components
DK2542300T3 (en) * 2010-03-01 2016-11-28 Inovio Pharmaceuticals Inc Tolerable (almost painless) and minimally invasive device for electroporation of the skin.
WO2011140274A2 (en) 2010-05-04 2011-11-10 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
US10330667B2 (en) 2010-06-25 2019-06-25 Intuity Medical, Inc. Analyte monitoring methods and systems
US8668675B2 (en) 2010-11-03 2014-03-11 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
DK3473296T3 (da) * 2011-06-28 2020-11-09 Inovio Pharmaceuticals Inc Minimalt invasiv dermal elektroporeringsenhed
US9782114B2 (en) 2011-08-03 2017-10-10 Intuity Medical, Inc. Devices and methods for body fluid sampling and analysis
WO2013138524A1 (en) 2012-03-14 2013-09-19 Medipacs, Inc. Smart polymer materials with excess reactive molecules
EP3549524B1 (de) 2012-03-30 2023-01-25 Insulet Corporation Flüssigkeitsabgabevorrichtung mit einem instrument für transkutanen zugang und einem einsatzmechanismus sowie blutzuckerüberwachungsvorrichtung zur verwendung damit
EP2839552A4 (de) 2012-04-18 2015-12-30 Cynosure Inc Pikosekunderlaservorrichtung und verfahren zur behandlung von zielgewebe damit
WO2013181361A2 (en) * 2012-05-30 2013-12-05 Scott Mcnulty System, method and apparatus for electromagnetic detection and analysis of biometric information
KR101372403B1 (ko) * 2012-06-21 2014-03-25 주식회사 파나시 압력감지 자동주사 시스템
US9999720B2 (en) 2012-09-27 2018-06-19 Palo Alto Research Center Incorporated Drug reconstitution and delivery device and methods
US9005108B2 (en) 2012-09-27 2015-04-14 Palo Alto Research Center Incorporated Multiple reservoir drug delivery device and methods
KR102187985B1 (ko) 2012-11-09 2020-12-07 도판 인사츠 가부시키가이샤 바늘 형상 구조체 및 그 제조 방법
KR102265808B1 (ko) 2012-12-21 2021-06-16 코리움, 인크. 치료제의 전달을 위한 마이크로어레이 및 그것의 사용방법
US9744341B2 (en) 2013-01-15 2017-08-29 Palo Alto Research Center Incorporated Devices and methods for intraluminal retention and drug delivery
CA2903748C (en) 2013-03-12 2021-11-02 Corium International, Inc. Microprojection applicators
WO2014145707A2 (en) 2013-03-15 2014-09-18 Cynosure, Inc. Picosecond optical radiation systems and methods of use
CA2903763C (en) 2013-03-15 2021-11-16 Corium International, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
EP2968119B1 (de) 2013-03-15 2019-09-18 Corium International, Inc. Mikroarray zur freisetzung therapeutischer wirkstoffe, verfahren zur verwendung und verfahren zur herstellung
WO2014151654A1 (en) 2013-03-15 2014-09-25 Corium International, Inc. Microarray for delivery of therapeutic agent and methods of use
AU2014237357B2 (en) 2013-03-15 2019-11-28 Corium Pharma Solutions, Inc. Multiple impact microprojection applicators and methods of use
US20140350518A1 (en) 2013-05-23 2014-11-27 Allergan, Inc. Syringe extrusion accessory
US20140350516A1 (en) 2013-05-23 2014-11-27 Allergan, Inc. Mechanical syringe accessory
JP2016522070A (ja) 2013-06-21 2016-07-28 インテュイティ メディカル インコーポレイテッド 可聴フィードバックを用いた分析物モニタリングシステム
US9561324B2 (en) 2013-07-19 2017-02-07 Bigfoot Biomedical, Inc. Infusion pump system and method
WO2015017561A1 (en) 2013-07-30 2015-02-05 Zosano Pharma, Inc. Low-profile microneedle patch applicator
US9297083B2 (en) 2013-12-16 2016-03-29 Palo Alto Research Center Incorporated Electrolytic gas generating devices, actuators, and methods
GB2523989B (en) 2014-01-30 2020-07-29 Insulet Netherlands B V Therapeutic product delivery system and method of pairing
US10029048B2 (en) 2014-05-13 2018-07-24 Allergan, Inc. High force injection devices
WO2015177976A1 (ja) 2014-05-20 2015-11-26 凸版印刷株式会社 針状体の製造方法、及び針状体
US10278675B2 (en) 2014-07-31 2019-05-07 Palo Alto Research Center Incorporated Implantable estrus detection devices, systems, and methods
US9801660B2 (en) 2014-07-31 2017-10-31 Palo Alto Research Center Incorporated Implantable fluid delivery devices, systems, and methods
EP3188714A1 (de) 2014-09-04 2017-07-12 Corium International, Inc. Mikrostrukturanordnung, verfahren zur herstellung und verfahren zur verwendung
US10226585B2 (en) 2014-10-01 2019-03-12 Allergan, Inc. Devices for injection and dosing
EP3216483B1 (de) * 2014-11-07 2019-03-20 Toppan Printing Co., Ltd. Nadelanordnung zur transdermalen verabreichung und verfahren zur herstellung davon
US10179229B2 (en) 2014-12-23 2019-01-15 Edge Systems Llc Devices and methods for treating the skin using a porous member
CA2977053C (en) 2015-02-18 2023-08-01 Insulet Corporation Fluid delivery and infusion devices, and methods of use thereof
EP3268063A4 (de) 2015-03-10 2018-10-31 Allergan Pharmaceuticals Holdings (Ireland) Unlimited Company Injektor mit mehreren nadeln
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
EP4546365A3 (de) 2015-11-24 2025-08-06 Insulet Corporation Tragbares automatisiertes arzneimittelabgabesystem
US10413665B2 (en) 2015-11-25 2019-09-17 Insulet Corporation Wearable medication delivery device
EP3374905A1 (de) 2016-01-13 2018-09-19 Bigfoot Biomedical, Inc. Benutzerschnittstelle für diabetesmanagementsystem
WO2017123703A2 (en) 2016-01-14 2017-07-20 Bigfoot Biomedical, Inc. Occlusion resolution in medication delivery devices, systems, and methods
EP4588437A3 (de) 2016-01-14 2025-10-01 Insulet Corporation Einstellung der insulinabgaberaten
US10363342B2 (en) 2016-02-04 2019-07-30 Insulet Corporation Anti-inflammatory cannula
CA3252327A1 (en) 2016-04-08 2025-02-24 Allergan, Inc. SUCTION AND INJECTION DEVICE
US12383166B2 (en) 2016-05-23 2025-08-12 Insulet Corporation Insulin delivery system and methods with risk-based set points
US10765807B2 (en) 2016-09-23 2020-09-08 Insulet Corporation Fluid delivery device with sensor
WO2018080923A1 (en) * 2016-10-28 2018-05-03 Georgetown University Non-invasive passive interstitial fluid collector
EP3500161A4 (de) 2016-12-12 2020-01-08 Bigfoot Biomedical, Inc. Alarme und warnungen für medikamentenabgabevorrichtungen und zugehörige systeme und verfahren
US10758675B2 (en) 2017-01-13 2020-09-01 Bigfoot Biomedical, Inc. System and method for adjusting insulin delivery
US10583250B2 (en) 2017-01-13 2020-03-10 Bigfoot Biomedical, Inc. System and method for adjusting insulin delivery
US10610644B2 (en) 2017-01-13 2020-04-07 Bigfoot Biomedical, Inc. Insulin delivery methods, systems and devices
US10500334B2 (en) 2017-01-13 2019-12-10 Bigfoot Biomedical, Inc. System and method for adjusting insulin delivery
EP3568862B1 (de) 2017-01-13 2026-03-18 Insulet Corporation System und verfahren zur anpassung der insulinabgabe
WO2018132765A1 (en) 2017-01-13 2018-07-19 Mazlish Bryan Insulin delivery methods, systems and devices
US11247206B2 (en) 2017-01-31 2022-02-15 Georgetown University Harvesting cell-free non-coding RNAS (CFNCRS) from interstitial fluid for sensitive biomarkers
WO2018156548A1 (en) 2017-02-22 2018-08-30 Insulet Corporation Needle insertion mechanisms for drug containers
USD867582S1 (en) 2017-03-24 2019-11-19 Allergan, Inc. Syringe device
US10898656B2 (en) 2017-09-26 2021-01-26 Insulet Corporation Needle mechanism module for drug delivery device
US11147931B2 (en) 2017-11-17 2021-10-19 Insulet Corporation Drug delivery device with air and backflow elimination
CA3092248A1 (en) 2018-02-26 2019-08-29 Mirko Mirkov Q-switched cavity dumped sub-nanosecond laser
USD928199S1 (en) 2018-04-02 2021-08-17 Bigfoot Biomedical, Inc. Medication delivery device with icons
US11565043B2 (en) 2018-05-04 2023-01-31 Insulet Corporation Safety constraints for a control algorithm based drug delivery system
US12562251B1 (en) 2018-05-09 2026-02-24 Bigfoot Biomedical, Inc. Computing architecture for assuring the provenance of medication therapy related parameters, and related systems, methods and devices
JP2022501139A (ja) 2018-09-28 2022-01-06 インスレット コーポレイション 人工膵臓システム用活動モード
WO2020077223A1 (en) 2018-10-11 2020-04-16 Insulet Corporation Event detection for drug delivery system
USD920343S1 (en) 2019-01-09 2021-05-25 Bigfoot Biomedical, Inc. Display screen or portion thereof with graphical user interface associated with insulin delivery
US11801344B2 (en) 2019-09-13 2023-10-31 Insulet Corporation Blood glucose rate of change modulation of meal and correction insulin bolus quantity
US11935637B2 (en) 2019-09-27 2024-03-19 Insulet Corporation Onboarding and total daily insulin adaptivity
EP4069082B1 (de) 2019-12-06 2024-06-05 Insulet Corporation Techniken und vorrichtungen zum bereitstellen von adaptivität und personalisierung bei der behandlung von diabetes
US11833329B2 (en) 2019-12-20 2023-12-05 Insulet Corporation Techniques for improved automatic drug delivery performance using delivery tendencies from past delivery history and use patterns
US12036389B2 (en) 2020-01-06 2024-07-16 Insulet Corporation Prediction of meal and/or exercise events based on persistent residuals
US12370307B2 (en) 2020-02-03 2025-07-29 Insulet Corporation Use of fuzzy logic in predicting user behavior affecting blood glucose concentration in a closed loop control system of an automated insulin delivery device
US11551802B2 (en) 2020-02-11 2023-01-10 Insulet Corporation Early meal detection and calorie intake detection
US11986630B2 (en) 2020-02-12 2024-05-21 Insulet Corporation Dual hormone delivery system for reducing impending hypoglycemia and/or hyperglycemia risk
US11547800B2 (en) 2020-02-12 2023-01-10 Insulet Corporation User parameter dependent cost function for personalized reduction of hypoglycemia and/or hyperglycemia in a closed loop artificial pancreas system
US11324889B2 (en) 2020-02-14 2022-05-10 Insulet Corporation Compensation for missing readings from a glucose monitor in an automated insulin delivery system
US12495994B2 (en) 2020-02-20 2025-12-16 Insulet Corporation Meal bolus subcategories in model based insulin therapy
US11607493B2 (en) 2020-04-06 2023-03-21 Insulet Corporation Initial total daily insulin setting for user onboarding
WO2022020197A1 (en) 2020-07-22 2022-01-27 Insulet Corporation Open-loop insulin delivery basal parameters based on insulin delivery records
US11684716B2 (en) 2020-07-31 2023-06-27 Insulet Corporation Techniques to reduce risk of occlusions in drug delivery systems
US12569619B2 (en) 2020-09-21 2026-03-10 Insulet Corporation Techniques for determining automated insulin delivery dosages
EP4221588A1 (de) 2020-09-30 2023-08-09 Insulet Corporation Sichere drahtlose kommunikation zwischen einem glucosemonitor und anderen vorrichtungen
US12128215B2 (en) 2020-09-30 2024-10-29 Insulet Corporation Drug delivery device with integrated optical-based glucose monitor
WO2022133218A1 (en) 2020-12-18 2022-06-23 Insulet Corporation Adhesive pad with a metallic coil for securing an on-body medical device
US11160925B1 (en) 2021-01-29 2021-11-02 Insulet Corporation Automatic drug delivery system for delivery of a GLP-1 therapeutic
WO2022192482A1 (en) 2021-03-10 2022-09-15 Insulet Corporation A medicament delivery device with an adjustable and piecewise analyte level cost component to address persistent positive analyte level excursions
US11904140B2 (en) 2021-03-10 2024-02-20 Insulet Corporation Adaptable asymmetric medicament cost component in a control system for medicament delivery
US12496398B2 (en) 2021-05-28 2025-12-16 Insulet Corporation Threshold based automatic glucose control response
US12406760B2 (en) 2021-06-07 2025-09-02 Insulet Corporation Exercise safety prediction based on physiological conditions
GB2622328B (en) * 2021-06-09 2025-10-08 Kao Corp Injection needle
US12514980B2 (en) 2021-06-30 2026-01-06 Insulet Corporation Adjustment of medicament delivery by a medicament delivery device based on menstrual cycle phase
US12521486B2 (en) 2021-07-16 2026-01-13 Insulet Corporation Method for modification of insulin delivery during pregnancy in automatic insulin delivery systems
WO2023049900A1 (en) 2021-09-27 2023-03-30 Insulet Corporation Techniques enabling adaptation of parameters in aid systems by user input
USD1116120S1 (en) 2021-10-11 2026-03-03 Hydrafacial Llc Skin treatment device
US11439754B1 (en) 2021-12-01 2022-09-13 Insulet Corporation Optimizing embedded formulations for drug delivery
CN218685709U (zh) * 2021-12-23 2023-03-24 苏州纳生微电子有限公司 微针阵列芯片
USD1112778S1 (en) 2022-03-04 2026-02-10 Hydrafacial Llc Light therapy device for skin care
EP4243030A1 (de) 2022-03-09 2023-09-13 Insulet Corporation Anpassung von medikamentenverabreichungsparametern in einem offenen regelkreis der medikamentenverabreichung
CN119654174A (zh) 2022-08-04 2025-03-18 英赛罗公司 具有双储器和固定不动的流体端口的泵机构
KR20250129777A (ko) 2023-01-06 2025-08-29 인슐렛 코포레이션 후속 자동 안전 제약 완화를 갖는 자동으로 또는 수동으로 개시되는 음식 볼러스 전달
USD1084369S1 (en) 2023-02-10 2025-07-15 Hydrafacial Llc Skin treatment tip

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
US4340048A (en) * 1981-03-28 1982-07-20 Alza Corporation Self-driven hypodermic injector
US4522622A (en) 1982-12-23 1985-06-11 Alza Corporation Multiple fluid pulse dispenser
US4775361A (en) * 1986-04-10 1988-10-04 The General Hospital Corporation Controlled removal of human stratum corneum by pulsed laser to enhance percutaneous transport
GB2221394B (en) * 1988-08-05 1992-03-04 Eilert Eilertsen An injection device
US5169389A (en) 1989-06-16 1992-12-08 Science, Inc. Fluid delivery apparatus
EP0429842B1 (de) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Vorrichtung zur transdermalen Applikation von Protein- oder Peptid-Medikamenten
US5115805A (en) 1990-02-23 1992-05-26 Cygnus Therapeutic Systems Ultrasound-enhanced delivery of materials into and through the skin
US5137817A (en) * 1990-10-05 1992-08-11 Amoco Corporation Apparatus and method for electroporation
US5279544A (en) 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
US5312456A (en) * 1991-01-31 1994-05-17 Carnegie Mellon University Micromechanical barb and method for making the same
US5223219A (en) 1992-04-10 1993-06-29 Biotrack, Inc. Analytical cartridge and system for detecting analytes in liquid samples
US5421816A (en) 1992-10-14 1995-06-06 Endodermic Medical Technologies Company Ultrasonic transdermal drug delivery system
US5582184A (en) * 1993-10-13 1996-12-10 Integ Incorporated Interstitial fluid collection and constituent measurement
US5458140A (en) * 1993-11-15 1995-10-17 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers
US5445611A (en) * 1993-12-08 1995-08-29 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal delivery with ultrasound and chemical enhancers
DE59505328D1 (de) 1994-12-09 1999-04-15 Novartis Ag Transdermales system
PT1563788E (pt) * 1995-08-29 2015-06-02 Nitto Denko Corp Microporação de pele humana para distribuição de fármaco e aplicações de monitorização
US5801057A (en) 1996-03-22 1998-09-01 Smart; Wilson H. Microsampling device and method of construction
JP2828064B2 (ja) * 1996-09-20 1998-11-25 日本電気株式会社 吸引浸出液採取方法および装置
US6093156A (en) 1996-12-06 2000-07-25 Abbott Laboratories Method and apparatus for obtaining blood for diagnostic tests
WO1998029134A2 (en) * 1996-12-31 1998-07-09 Altea Technologies, Inc. Microporation of tissue for delivery of bioactive agents
US6155992A (en) 1997-12-02 2000-12-05 Abbott Laboratories Method and apparatus for obtaining interstitial fluid for diagnostic tests
DE69928229T2 (de) 1998-02-17 2006-08-03 Abbott Laboratories, Abbott Park Gerät zum entnehmen und analysieren von interstitieller flüssigkeit
US6022316A (en) * 1998-03-06 2000-02-08 Spectrx, Inc. Apparatus and method for electroporation of microporated tissue for enhancing flux rates for monitoring and delivery applications

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JP2000513971A (ja) 2000-10-24
US20020010412A1 (en) 2002-01-24
ES2200187T3 (es) 2004-03-01
CA2259437A1 (en) 1998-01-08
DE69722414D1 (de) 2003-07-03
JP3942640B2 (ja) 2007-07-11
AU3880697A (en) 1998-01-21
US6183434B1 (en) 2001-02-06
WO1998000193A1 (en) 1998-01-08
EP0921840B1 (de) 2003-05-28
EP0921840A1 (de) 1999-06-16
EP0921840A4 (de) 2000-04-12
DE69722414T2 (de) 2004-05-19
CA2259437C (en) 2006-12-05
DK0921840T3 (da) 2003-09-22

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