NO20062361L - Bakterielle virulens faktorer og anvendelser derav - Google Patents
Bakterielle virulens faktorer og anvendelser deravInfo
- Publication number
- NO20062361L NO20062361L NO20062361A NO20062361A NO20062361L NO 20062361 L NO20062361 L NO 20062361L NO 20062361 A NO20062361 A NO 20062361A NO 20062361 A NO20062361 A NO 20062361A NO 20062361 L NO20062361 L NO 20062361L
- Authority
- NO
- Norway
- Prior art keywords
- virulence factors
- bacterial virulence
- polypeptides
- secreted proteins
- pathogens
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0258—Escherichia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Gram-negative bacteria
- C07K16/1228—Enterobacterales (O), e.g. Citrobacter (G), Serratia (G), Proteus (G), Providencia (G), Morganella (G) or Yersinia (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Gram-negative bacteria
- C07K16/1228—Enterobacterales (O), e.g. Citrobacter (G), Serratia (G), Proteus (G), Providencia (G), Morganella (G) or Yersinia (G)
- C07K16/1232—Escherichia (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/56916—Enterobacteria, e.g. shigella, salmonella, klebsiella, serratia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Food Science & Technology (AREA)
- Virology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
Abstract
Oppfinnelsen angår, til dels, utskilte proteiner av bakterielle patogener og metoder for anvendelse av dem. Mer spesifikt tilveiebringer oppfinnelsen til dels mange nye vanlige utskilte proteiner for A/E-patogener. I noen utførelsesformer ifølge oppfinnelsen er disse polypeptider og nukleinsyremolekyler som koder for disse polypeptider eller deler derav, anvendelige som vaksiner, diagnostikk- eller medikamentscreening-verktøy for A/E-patogene infeksjoner eller som reagenser.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51570303P | 2003-10-31 | 2003-10-31 | |
| PCT/CA2004/001891 WO2005042746A1 (en) | 2003-10-31 | 2004-10-29 | Bacterial virulence factors and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20062361L true NO20062361L (no) | 2006-07-20 |
Family
ID=34549436
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20062361A NO20062361L (no) | 2003-10-31 | 2006-05-23 | Bakterielle virulens faktorer og anvendelser derav |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US8758771B2 (no) |
| EP (3) | EP2462948A1 (no) |
| JP (2) | JP5100122B2 (no) |
| KR (3) | KR101242445B1 (no) |
| CN (2) | CN1922324B (no) |
| AR (1) | AR050050A1 (no) |
| AU (2) | AU2004286002B2 (no) |
| BR (1) | BRPI0415816A (no) |
| CA (1) | CA2543763A1 (no) |
| MX (1) | MXPA06004858A (no) |
| NO (1) | NO20062361L (no) |
| NZ (1) | NZ547156A (no) |
| RU (2) | RU2465331C2 (no) |
| UA (1) | UA94206C2 (no) |
| WO (1) | WO2005042746A1 (no) |
| ZA (1) | ZA200604412B (no) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0415816A (pt) | 2003-10-31 | 2006-12-26 | Univ British Columbia | composição, bactéria ou um preparado da mesma, método para detectar a presença de um patógeno de a/e em uma amostra, método para provocar uma resposta imunológica contra um patógeno de a/e ou um componente do mesmo em um animal, método para reduzir a colonização de um patógeno de a/e em um animal, método para reduzir a disseminação de um patógeno de a/e em um animal, método para o tratamento ou a prevenção da infecção por um patógeno de a/e, método para atenuar a virulência de um patógeno de a/e, método para a seleção de um composto que atenue a virulência de um patógeno e a/e, método para a produção de um polipeptìdio de patógeno de a/e, polipeptìdio recombinante, molécula de ácido nucléico isolada, vetor, célula hospedeira, uso da composição e kit |
| US9107864B2 (en) * | 2004-06-07 | 2015-08-18 | Qu Biologics Inc. | Tissue targeted antigenic activation of the immune response to treat cancers |
| US20090197249A1 (en) * | 2004-11-01 | 2009-08-06 | George Mason University | Compositions and methods for diagnosing colon disorders |
| CA2651328A1 (en) * | 2006-05-05 | 2007-11-15 | Opexa Therapeutics | T-cell vaccine |
| US20080124355A1 (en) | 2006-09-22 | 2008-05-29 | David Gordon Bermudes | Live bacterial vaccines for viral infection prophylaxis or treatment |
| ES2335177B1 (es) * | 2008-09-19 | 2011-02-28 | Archivel Farma, S.L. | Agente inmunoterapeutico apropiado para la profilaxis primaria de la tuberculosis. |
| US8241623B1 (en) | 2009-02-09 | 2012-08-14 | David Bermudes | Protease sensitivity expression system |
| GB0909198D0 (en) * | 2009-05-28 | 2009-07-15 | Queen Mary & Westfield College | Methods and composition for treating NF-kappa B mediated disorders |
| WO2011005587A1 (en) * | 2009-06-24 | 2011-01-13 | University Of Dubuque | Vaccine compositions and methods of use to protect against infectious disease |
| WO2011007350A2 (en) * | 2009-07-13 | 2011-01-20 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Immunomodulatory agents and a tissue-targeted delivery system thereof for the treatment of immune-related disorders |
| EP2292799A1 (en) | 2009-08-11 | 2011-03-09 | Agence Française de Securité Sanitaire des Aliments | An assay for determining a molecular risk assessment of stec isolates |
| US8524220B1 (en) | 2010-02-09 | 2013-09-03 | David Gordon Bermudes | Protease inhibitor: protease sensitivity expression system composition and methods improving the therapeutic activity and specificity of proteins delivered by bacteria |
| US9597379B1 (en) | 2010-02-09 | 2017-03-21 | David Gordon Bermudes | Protease inhibitor combination with therapeutic proteins including antibodies |
| US8771669B1 (en) | 2010-02-09 | 2014-07-08 | David Gordon Bermudes | Immunization and/or treatment of parasites and infectious agents by live bacteria |
| WO2012026712A2 (ko) | 2010-08-23 | 2012-03-01 | 주식회사 강스템홀딩스 | Nod2의 아고니스트를 처리한 줄기세포 또는 그 배양물을 포함하는 면역질환 또는 염증질환의 예방 또는 치료용 약학조성물 |
| RU2497541C1 (ru) * | 2012-07-20 | 2013-11-10 | федеральное государственное бюджетное учреждение "Научно-исследовательский институт эпидемиологии и микробиологии имени почётного академика Н.Ф. Гамалеи" Министерства здравоохранения Российской Федерации | Фармацевтическая композиция на основе лигандов паттерн-распознающих рецепторов, способ ее использования в качестве иммуностимулятора для лечения инфекций, вызванных бактериальными и вирусными патогенами, способ ее использования в качестве адъюванта в составе вакцин |
| US9593339B1 (en) | 2013-02-14 | 2017-03-14 | David Gordon Bermudes | Bacteria carrying bacteriophage and protease inhibitors for the treatment of disorders and methods of treatment |
| US9579370B2 (en) | 2014-03-04 | 2017-02-28 | The Board Of Regents Of The University Of Texas System | Compositions and methods for enterohemorrhagic Escherichia coli (EHEC)vaccination |
| US10226520B2 (en) | 2014-03-04 | 2019-03-12 | The Board Of Regents Of The University Of Texa System | Compositions and methods for enterohemorrhagic Escherichia coli (EHEC) vaccination |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| CN105294840B (zh) * | 2015-11-20 | 2018-08-17 | 深圳市南山区人民医院 | 一种用于预防和治疗肠致病大肠杆菌感染的肽段 |
| CN105821065A (zh) * | 2016-04-29 | 2016-08-03 | 南方医科大学 | 一种双抗原重组蛋白及其制备方法和应用 |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| US20210054033A1 (en) * | 2018-01-25 | 2021-02-25 | The Wistar Institute Of Anatomy And Biology | Methods and compositions for use of recombinant bacterial effector proteins as anti-inflammatory agents |
| BR112020017257A2 (pt) * | 2018-03-29 | 2020-12-22 | Kimberly-Clark Worldwide, Inc. | Sensor, artigo absorvente, e, método para indicar um potencial problema de pele ou gastrointestinal. |
| WO2020223601A1 (en) * | 2019-05-01 | 2020-11-05 | Innate Biologics Llc | Immunomodulatory compositions and methods |
| CN113174389B (zh) * | 2021-05-27 | 2023-06-16 | 昆明理工大学 | 一种岷江百合诱导型启动子pr4及其应用 |
| CN118910018B (zh) * | 2024-07-31 | 2025-03-21 | 徐州医科大学 | 一种利用位点指引的突变形成技术增强NleC蛋白稳定性的优化方法 |
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| US4310550A (en) | 1979-10-26 | 1982-01-12 | Pfizer Inc. | Lipid amines formulated with fat or lipid emulsions as vaccine adjuvants |
| US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
| US4708871A (en) | 1983-03-08 | 1987-11-24 | Commonwealth Serum Laboratories Commission | Antigenically active amino acid sequences |
| US4744984A (en) | 1985-10-08 | 1988-05-17 | Vetrepharm Research, Inc. | Antiviral immunotherapeutic agent and preparation thereof |
| US5151267A (en) | 1988-07-15 | 1992-09-29 | University Of Saskatchewan | Bovine herpesvirus type 1 polypeptides and vaccines |
| SE9100556D0 (sv) * | 1991-02-26 | 1991-02-26 | Holmgren Jan | Preparation and use of formalin-killed colonization-factor-antigen (cfa)-expressing e coli organisms for vaccination against enteric infection/diarrhea caused by enterotoxigenic e coli bacteria in humans |
| US5370989A (en) * | 1992-04-03 | 1994-12-06 | The Trustees Of Columbia University In The City Of New York | Solution for prolonged organ preservation |
| RU2043771C1 (ru) * | 1993-02-25 | 1995-09-20 | Михаил Константинович Пирожков | Вакцина против эшерихиоза животных |
| US5951988A (en) | 1993-03-30 | 1999-09-14 | University Of Saskatchewan | Adjuvant formulation with enhanced immunogenic activity, and related compositions and methods |
| DE69426051T2 (de) | 1993-07-30 | 2001-05-10 | Akzo Nobel N.V., Arnheim/Arnhem | Impfstoff für Geflügel |
| WO1996040861A1 (en) | 1995-06-07 | 1996-12-19 | Biolog, Inc. | Microbiological media for isolation and identification of enteric pathogens such as e. coli and salmonella |
| FR2747394B1 (fr) | 1996-04-15 | 1998-07-03 | Rambach Alain | Milieu de culture pour la mise en evidence des bacteries e. coli enterohemorragiques, et procede pour sa mise en evidence |
| BR9710433A (pt) | 1996-04-23 | 1999-10-05 | Univ British Columbia | Proteínas associada a escherichia coli patogênica |
| DK1023442T3 (da) | 1997-10-16 | 2011-03-14 | Univ Georgia | Transgenetiske fugle og fremstilling af proteiner |
| US7208574B1 (en) | 1997-11-12 | 2007-04-24 | The University Of British Columbia | Host receptor for pathogenic bacteria |
| ATE438721T1 (de) | 1997-11-12 | 2009-08-15 | Univ British Columbia | Hp90:wirtsrezeptor für pathogene bakterien |
| US6365723B1 (en) * | 1998-12-04 | 2002-04-02 | Wisconsin Alumni Research Foundation | Sequences of E. coli O157 |
| US20020132788A1 (en) | 2000-11-06 | 2002-09-19 | David Lewis | Inhibition of gene expression by delivery of small interfering RNA to post-embryonic animal cells in vivo |
| US20020173478A1 (en) | 2000-11-14 | 2002-11-21 | The Trustees Of The University Of Pennsylvania | Post-transcriptional gene silencing by RNAi in mammalian cells |
| AU2002218927B2 (en) | 2001-01-04 | 2007-08-30 | The University Of British Columbia | Enterohemorrhagic Escherichia coli vaccine |
| JP2002355074A (ja) | 2001-01-24 | 2002-12-10 | Univ Tsukuba | 腸管出血性病原性大腸菌o157:h7に特異的な核酸分子およびポリペプチド並びにこれらの使用方法 |
| TWI350174B (en) * | 2003-03-12 | 2011-10-11 | Wyeth Corp | Adjuvanted bovine vaccines |
| BRPI0415816A (pt) | 2003-10-31 | 2006-12-26 | Univ British Columbia | composição, bactéria ou um preparado da mesma, método para detectar a presença de um patógeno de a/e em uma amostra, método para provocar uma resposta imunológica contra um patógeno de a/e ou um componente do mesmo em um animal, método para reduzir a colonização de um patógeno de a/e em um animal, método para reduzir a disseminação de um patógeno de a/e em um animal, método para o tratamento ou a prevenção da infecção por um patógeno de a/e, método para atenuar a virulência de um patógeno de a/e, método para a seleção de um composto que atenue a virulência de um patógeno e a/e, método para a produção de um polipeptìdio de patógeno de a/e, polipeptìdio recombinante, molécula de ácido nucléico isolada, vetor, célula hospedeira, uso da composição e kit |
-
2004
- 2004-10-29 BR BRPI0415816-4A patent/BRPI0415816A/pt not_active IP Right Cessation
- 2004-10-29 US US10/577,742 patent/US8758771B2/en not_active Expired - Fee Related
- 2004-10-29 UA UAA200605985A patent/UA94206C2/ru unknown
- 2004-10-29 EP EP11184778A patent/EP2462948A1/en not_active Withdrawn
- 2004-10-29 EP EP04789798A patent/EP1692287A4/en not_active Withdrawn
- 2004-10-29 CA CA002543763A patent/CA2543763A1/en not_active Abandoned
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- 2004-10-29 KR KR1020067010661A patent/KR101242445B1/ko not_active Expired - Fee Related
- 2004-10-29 AU AU2004286002A patent/AU2004286002B2/en not_active Ceased
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- 2004-10-29 JP JP2006537022A patent/JP5100122B2/ja not_active Expired - Fee Related
- 2004-10-29 ZA ZA200604412A patent/ZA200604412B/xx unknown
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- 2004-10-29 KR KR1020137001391A patent/KR20130018999A/ko not_active Ceased
- 2004-10-29 WO PCT/CA2004/001891 patent/WO2005042746A1/en not_active Ceased
- 2004-10-29 KR KR1020117019259A patent/KR20110102956A/ko not_active Abandoned
- 2004-10-29 CN CN200910206659A patent/CN101711861A/zh active Pending
- 2004-10-29 MX MXPA06004858A patent/MXPA06004858A/es active IP Right Grant
- 2004-11-02 AR ARP040104025A patent/AR050050A1/es unknown
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- 2011-07-08 JP JP2011152074A patent/JP2011250790A/ja active Pending
- 2011-07-13 US US13/182,334 patent/US8507249B2/en not_active Expired - Fee Related
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Also Published As
| Publication number | Publication date |
|---|---|
| EP2462948A1 (en) | 2012-06-13 |
| KR20110102956A (ko) | 2011-09-19 |
| JP2007531511A (ja) | 2007-11-08 |
| EP1692287A1 (en) | 2006-08-23 |
| CA2543763A1 (en) | 2005-05-12 |
| CN1922324B (zh) | 2010-06-09 |
| JP5100122B2 (ja) | 2012-12-19 |
| KR20070031848A (ko) | 2007-03-20 |
| RU2012122559A (ru) | 2013-12-10 |
| AR050050A1 (es) | 2006-09-27 |
| BRPI0415816A (pt) | 2006-12-26 |
| AU2011201889A1 (en) | 2011-05-19 |
| KR20130018999A (ko) | 2013-02-25 |
| AU2011201889B2 (en) | 2013-04-04 |
| WO2005042746A1 (en) | 2005-05-12 |
| ZA200604412B (en) | 2007-09-26 |
| CN1922324A (zh) | 2007-02-28 |
| RU2465331C2 (ru) | 2012-10-27 |
| MXPA06004858A (es) | 2007-04-16 |
| JP2011250790A (ja) | 2011-12-15 |
| NZ547156A (en) | 2009-08-28 |
| AU2004286002B2 (en) | 2011-01-27 |
| UA94206C2 (ru) | 2011-04-26 |
| RU2006118803A (ru) | 2007-12-10 |
| EP2383287A1 (en) | 2011-11-02 |
| KR101242445B1 (ko) | 2013-03-15 |
| EP1692287A4 (en) | 2007-03-28 |
| AU2004286002A1 (en) | 2005-05-12 |
| US20070041997A1 (en) | 2007-02-22 |
| US20120064572A1 (en) | 2012-03-15 |
| US8507249B2 (en) | 2013-08-13 |
| CN101711861A (zh) | 2010-05-26 |
| US8758771B2 (en) | 2014-06-24 |
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