NO20062619L - Doseringssystem med kontrollert frigivning for nasale anvendelser - Google Patents
Doseringssystem med kontrollert frigivning for nasale anvendelserInfo
- Publication number
- NO20062619L NO20062619L NO20062619A NO20062619A NO20062619L NO 20062619 L NO20062619 L NO 20062619L NO 20062619 A NO20062619 A NO 20062619A NO 20062619 A NO20062619 A NO 20062619A NO 20062619 L NO20062619 L NO 20062619L
- Authority
- NO
- Norway
- Prior art keywords
- controlled release
- dosing system
- release dosing
- nasal applications
- nasal
- Prior art date
Links
- 238000013270 controlled release Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000003629 gastrointestinal hormone Substances 0.000 abstract 1
- 230000005923 long-lasting effect Effects 0.000 abstract 1
- 230000002459 sustained effect Effects 0.000 abstract 1
- 230000001839 systemic circulation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Otolaryngology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Pulmonology (AREA)
- Pregnancy & Childbirth (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Oppfinnelsen vedrører et preparat for nasal administrering for kontrollert fligivning av kjørmshormoner til systemisk sirkulasjon, spesielt til formulering som muliggjør at den aktive ingrediensen absorberes på en vedvarende måte for å tilveiebringe en bedre biotilgjengelighet ved meget lave doser og langvarig virkning.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03025769A EP1530965B1 (en) | 2003-11-11 | 2003-11-11 | Controlled release delivery system of sexual hormones for nasal application |
| PCT/EP2004/012122 WO2005044273A1 (en) | 2003-11-11 | 2004-10-27 | Controlled release delivery system for nasal applications |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20062619L true NO20062619L (no) | 2006-06-07 |
| NO338665B1 NO338665B1 (no) | 2016-09-26 |
Family
ID=34429314
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20062619A NO338665B1 (no) | 2003-11-11 | 2006-06-07 | Doseringssystem med kontrollert frigivning for nasale anvendelser |
Country Status (23)
| Country | Link |
|---|---|
| US (6) | US20050100564A1 (no) |
| EP (1) | EP1530965B1 (no) |
| JP (1) | JP4616270B2 (no) |
| KR (1) | KR100861443B1 (no) |
| AR (1) | AR047722A1 (no) |
| AT (1) | ATE319426T1 (no) |
| AU (1) | AU2004286781B2 (no) |
| BR (1) | BRPI0416370B8 (no) |
| CA (1) | CA2541498C (no) |
| DE (1) | DE60303854T2 (no) |
| DK (1) | DK1530965T3 (no) |
| ES (1) | ES2258694T3 (no) |
| HR (1) | HRP20060147B1 (no) |
| MY (1) | MY131483A (no) |
| NO (1) | NO338665B1 (no) |
| PL (1) | PL219338B1 (no) |
| PT (1) | PT1530965E (no) |
| RU (1) | RU2331423C2 (no) |
| SA (1) | SA04250363B1 (no) |
| SI (1) | SI1530965T1 (no) |
| TW (1) | TWI350176B (no) |
| WO (1) | WO2005044273A1 (no) |
| ZA (1) | ZA200603115B (no) |
Families Citing this family (68)
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|---|---|---|---|---|
| HU224208B1 (hu) | 1996-10-01 | 2005-06-28 | Magotteaux International S.A. | Összetett anyagú kopásálló alkatrész |
| HU226782B1 (en) | 2001-12-04 | 2009-10-28 | Magotteaux Int | Cast part with enhanced wear resistance |
| ES2258694T3 (es) | 2003-11-11 | 2006-09-01 | Mattern, Udo | Sistema de administracion de liberacion controlada de hormonas sexuales para aplicaciones nasales. |
| US8784869B2 (en) | 2003-11-11 | 2014-07-22 | Mattern Pharma Ag | Controlled release delivery system for nasal applications and methods of treatment |
| NZ551356A (en) | 2004-05-11 | 2009-09-25 | Emotional Brain Bv | Pharmaceutical formulations and uses thereof in the treatment of female sexual dysfunction |
| US20060140820A1 (en) | 2004-12-28 | 2006-06-29 | Udo Mattern | Use of a container of an inorganic additive containing plastic material |
| EP1790343A1 (en) * | 2005-11-11 | 2007-05-30 | Emotional Brain B.V. | Pharmaceuticals formulations and uses thereof in the treatment of female sexual dysfunction |
| GB2437488A (en) * | 2006-04-25 | 2007-10-31 | Optinose As | Pharmaceutical oily formulation for nasal or buccal administration |
| CA2664427C (en) * | 2006-10-04 | 2012-06-05 | M & P Patent Aktiengesellschaft | Controlled release delivery system for nasal application of neurotransmitters |
| US8147980B2 (en) | 2006-11-01 | 2012-04-03 | Aia Engineering, Ltd. | Wear-resistant metal matrix ceramic composite parts and methods of manufacturing thereof |
| EP1925307A1 (en) * | 2006-11-03 | 2008-05-28 | Emotional Brain B.V. | Use of 3-alpha-androstanediol in the treatment of sexual dysfunction |
| DE102010023949A1 (de) * | 2010-06-16 | 2011-12-22 | F. Holzer Gmbh | In-situ Lecithin-Mikroemulsionsgel-Formulierung |
| GB2482868A (en) | 2010-08-16 | 2012-02-22 | Franciscus Wilhelmus Henricus Maria Merkus | A testosterone liquid spray formulation for oromucosal administration |
| US20130040923A1 (en) * | 2011-05-13 | 2013-02-14 | Trimel Pharmaceuticals Corporation | Intranasal lower dosage strength testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder |
| CN103687587A (zh) * | 2011-05-13 | 2014-03-26 | 特利默生物医药有限公司 | 鼻内较低剂量强度睾酮凝胶制剂及其用于治疗性快感缺失病或性欲减退疾患的应用 |
| US20130040922A1 (en) * | 2011-05-13 | 2013-02-14 | Trimel Pharmaceuticals Corporation | Intranasal 0.45% and 0.48% testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder |
| US9757388B2 (en) | 2011-05-13 | 2017-09-12 | Acerus Pharmaceuticals Srl | Intranasal methods of treating women for anorgasmia with 0.6% and 0.72% testosterone gels |
| US20130045958A1 (en) * | 2011-05-13 | 2013-02-21 | Trimel Pharmaceuticals Corporation | Intranasal 0.15% and 0.24% testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder |
| MX395212B (es) | 2011-05-15 | 2025-03-21 | Acerus Biopharma Inc | Geles nasales de liberación controlada de testosterona, métodos y sistemas aplicadores multidosis pre cargados para administración pernasal. |
| EA202192397A3 (ru) * | 2011-05-16 | 2022-03-31 | Эйсерус Биофарма Инк. | Интраназальные биоадгезивные тестостероновые составы в виде гелей и их применение для лечения мужского гипогонадизма |
| RS62297B1 (sr) | 2011-11-23 | 2021-09-30 | Therapeuticsmd Inc | Prirodne kombinovane hormonske supstitucione formulacije i terapije |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| EP2875826B1 (en) | 2012-05-11 | 2017-08-23 | KAEL-GemVax Co.,Ltd | Composition for preventing or treating sepsis |
| KR102578891B1 (ko) | 2012-05-11 | 2023-09-15 | 주식회사 젬백스앤카엘 | 항염증 활성을 갖는 펩티드 및 이를 포함하는 조성물 |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
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| ES2981865T3 (es) | 2012-07-11 | 2024-10-10 | Gemvax & Kael Co Ltd | Conjugado que comprende un péptido de penetración celular y composiciones que comprenden el mismo |
| WO2014083432A2 (en) * | 2012-11-14 | 2014-06-05 | Trimel Biopharma Srl | Female intranasal lower dosage strength testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder |
| WO2014076569A2 (en) * | 2012-11-14 | 2014-05-22 | Trimel Biopharma Srl | Controlled release topical testosterone formulations and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
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| ES2809251T3 (es) | 2013-12-17 | 2021-03-03 | Gemvax & Kael Co Ltd | Composición para tratar cáncer de próstata |
| EP3130345B9 (en) | 2014-04-11 | 2022-05-04 | Gemvax & Kael Co., Ltd. | Peptide having fibrosis inhibitory activity and composition containing same |
| ES2962532T3 (es) | 2014-04-30 | 2024-03-19 | Gemvax & Kael Co Ltd | Composición para el trasplante de órganos, tejidos o células, kit y procedimiento de trasplante |
| RU2016143081A (ru) | 2014-05-22 | 2018-06-26 | Терапьютиксмд, Инк. | Натуральные комбинированные гормонозаместительные составы и терапии |
| EP3174542A4 (en) | 2014-07-29 | 2018-01-03 | TherapeuticsMD, Inc. | Transdermal cream |
| DK3185872T3 (da) | 2014-08-28 | 2021-06-21 | Univ Texas | Formulering af testosteron og metoder til behandling hermed |
| KR102413243B1 (ko) | 2014-12-23 | 2022-06-27 | 주식회사 젬백스앤카엘 | 안질환 치료 펩티드 및 이를 포함하는 안질환 치료용 조성물 |
| EP3263122B1 (en) | 2015-02-27 | 2020-05-06 | Gemvax & Kael Co., Ltd. | Peptide for preventing hearing loss, and composition comprising same |
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-
2003
- 2003-11-11 ES ES03025769T patent/ES2258694T3/es not_active Expired - Lifetime
- 2003-11-11 EP EP03025769A patent/EP1530965B1/en not_active Expired - Lifetime
- 2003-11-11 AT AT03025769T patent/ATE319426T1/de active
- 2003-11-11 SI SI200330194T patent/SI1530965T1/sl unknown
- 2003-11-11 PT PT03025769T patent/PT1530965E/pt unknown
- 2003-11-11 DE DE60303854T patent/DE60303854T2/de not_active Expired - Lifetime
- 2003-11-11 DK DK03025769T patent/DK1530965T3/da active
-
2004
- 2004-02-04 US US10/772,964 patent/US20050100564A1/en not_active Abandoned
- 2004-09-23 MY MYPI20043889A patent/MY131483A/en unknown
- 2004-10-04 TW TW093129982A patent/TWI350176B/zh not_active IP Right Cessation
- 2004-10-05 AR ARP040103611A patent/AR047722A1/es not_active Application Discontinuation
- 2004-10-27 BR BRPI0416370A patent/BRPI0416370B8/pt not_active IP Right Cessation
- 2004-10-27 PL PL379867A patent/PL219338B1/pl unknown
- 2004-10-27 ZA ZA200603115A patent/ZA200603115B/en unknown
- 2004-10-27 WO PCT/EP2004/012122 patent/WO2005044273A1/en not_active Ceased
- 2004-10-27 JP JP2006538697A patent/JP4616270B2/ja not_active Expired - Fee Related
- 2004-10-27 HR HRP20060147AA patent/HRP20060147B1/hr not_active IP Right Cessation
- 2004-10-27 CA CA002541498A patent/CA2541498C/en not_active Expired - Lifetime
- 2004-10-27 AU AU2004286781A patent/AU2004286781B2/en not_active Ceased
- 2004-10-27 KR KR1020067009182A patent/KR100861443B1/ko not_active Expired - Fee Related
- 2004-10-27 RU RU2006120468/15A patent/RU2331423C2/ru active
- 2004-11-02 SA SA04250363A patent/SA04250363B1/ar unknown
-
2006
- 2006-06-07 NO NO20062619A patent/NO338665B1/no not_active IP Right Cessation
- 2006-11-15 US US11/560,187 patent/US20070149454A1/en not_active Abandoned
-
2010
- 2010-06-08 US US12/796,165 patent/US20100311707A1/en not_active Abandoned
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2011
- 2011-07-29 US US13/194,853 patent/US8784882B2/en not_active Expired - Lifetime
- 2011-07-30 US US13/194,928 patent/US8574622B2/en not_active Expired - Fee Related
- 2011-12-10 US US13/316,494 patent/US8877230B2/en not_active Expired - Lifetime
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