NO20063821L - Kinolinderivater for anvendelse som mykobakterielle inhibitorer - Google Patents

Kinolinderivater for anvendelse som mykobakterielle inhibitorer

Info

Publication number
NO20063821L
NO20063821L NO20063821A NO20063821A NO20063821L NO 20063821 L NO20063821 L NO 20063821L NO 20063821 A NO20063821 A NO 20063821A NO 20063821 A NO20063821 A NO 20063821A NO 20063821 L NO20063821 L NO 20063821L
Authority
NO
Norway
Prior art keywords
quinoline derivatives
mycobacterial
mycobacterial inhibitors
inhibitors
derivatives
Prior art date
Application number
NO20063821A
Other languages
English (en)
Other versions
NO337253B1 (no
Inventor
Elisabeth Therese Jea Pasquier
Jerome Emile George Guillemont
David Francis Alain Lancois
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NO20063821L publication Critical patent/NO20063821L/no
Publication of NO337253B1 publication Critical patent/NO337253B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)

Abstract

Den foreliggende oppfinnelse vedrører nye substituerte kinolinderivater ifølge den generelle formel (I) nyttige i behandlingen av mykobakterielle sykdommer slik som TB.
NO20063821A 2004-01-29 2006-08-28 Kinolinderivater for anvendelse som mykobakterielle inhibitorer NO337253B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04075286 2004-01-29
PCT/EP2005/050375 WO2005075428A1 (en) 2004-01-29 2005-01-28 Quinoline derivatives for use as mycobacterial inhibitors

Publications (2)

Publication Number Publication Date
NO20063821L true NO20063821L (no) 2006-08-28
NO337253B1 NO337253B1 (no) 2016-02-22

Family

ID=34833674

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20063821A NO337253B1 (no) 2004-01-29 2006-08-28 Kinolinderivater for anvendelse som mykobakterielle inhibitorer

Country Status (20)

Country Link
US (1) US7790894B2 (no)
EP (1) EP1713776B1 (no)
JP (1) JP4919810B2 (no)
KR (1) KR101160183B1 (no)
CN (1) CN1910154B (no)
AP (1) AP2321A (no)
AT (1) ATE395336T1 (no)
AU (1) AU2005210036B2 (no)
BR (1) BRPI0507312A (no)
CA (1) CA2554049C (no)
DE (1) DE602005006744D1 (no)
EA (1) EA011572B9 (no)
ES (1) ES2306098T3 (no)
IL (1) IL177101A (no)
MX (1) MXPA06008596A (no)
NO (1) NO337253B1 (no)
NZ (1) NZ547614A (no)
UA (1) UA83875C2 (no)
WO (1) WO2005075428A1 (no)
ZA (1) ZA200606291B (no)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO341242B1 (no) * 2005-08-03 2017-09-25 Janssen Pharmaceutica Nv Kinolinderivater som antibakterielle midler

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO2683B1 (en) * 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان. في Quinoline antibacterial derivatives
JO2970B1 (en) 2006-12-06 2016-03-15 جانسين فارماسوتيكا ان. في Quinoline antibacterial derivatives
JO2685B1 (en) * 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان في Quinoline antibacterial derivatives
JO2684B1 (en) * 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان في Quinoline antibacterial derivatives
JO3271B1 (ar) 2006-12-06 2018-09-16 Janssen Pharmaceutica Nv مشتقات الكوينولين المضادة للجراثيم
CA2751892A1 (en) 2009-01-15 2010-07-22 Rutgers, The State University Of New Jersey Benzo [c] phenanthridines as antimicrobial agents
CA2760526A1 (en) 2009-04-30 2010-11-04 Rutgers, The State University Of New Jersey Antimicrobial agents
US8933096B2 (en) 2010-06-09 2015-01-13 Rugers, The State University of New Jersey Antimicrobial agents
WO2011163610A2 (en) * 2010-06-25 2011-12-29 Rutgers, The State University Of New Jersey Antimicrobial agents
RU2486175C2 (ru) * 2011-09-12 2013-06-27 Закрытое Акционерное Общество "Фарм-Синтез" Производные хинолина, в частности 5,6,7-замещенные 1-(2-хлорхинолин-3-ил)-4-диметиламино-2-(нафталин-1-ил)-1-фенилбутан-2-олы, способ получения и применение соединений
WO2013106756A2 (en) 2012-01-13 2013-07-18 Rutgers, The State University Of New Jersey Antimicrobial agents
EP2828245A1 (en) 2012-03-21 2015-01-28 Rutgers, The State University of New Jersey Antimicrobial agents
ES2576491T3 (es) 2012-04-27 2016-07-07 Janssen Pharmaceutica, N.V. Derivados de quinolina antibacterianos
AU2013254670B2 (en) 2012-04-27 2017-03-30 Janssen Pharmaceutica Nv Antibacterial quinoline derivatives
MY189505A (en) 2012-10-16 2022-02-16 Janssen Pharmaceutica Nv Methylene linked quinolinyl modulators of roryt
HK1213887A1 (zh) 2012-10-16 2016-07-15 Janssen Pharmaceutica N.V. RORγt的苯基连接的喹啉基调节剂
WO2014062655A1 (en) 2012-10-16 2014-04-24 Janssen Pharmaceutica Nv HETEROARYL LINKED QUINOLINYL MODULATORS OF RORyt
CA2926339A1 (en) 2013-10-15 2015-04-23 Janssen Pharmaceutica Nv Alkyl linked quinolinyl modulators of roryt
US10555941B2 (en) 2013-10-15 2020-02-11 Janssen Pharmaceutica Nv Alkyl linked quinolinyl modulators of RORγt
US9284308B2 (en) 2013-10-15 2016-03-15 Janssen Pharmaceutica Nv Methylene linked quinolinyl modulators of RORγt
US9221804B2 (en) 2013-10-15 2015-12-29 Janssen Pharmaceutica Nv Secondary alcohol quinolinyl modulators of RORγt
US9328095B2 (en) 2013-10-15 2016-05-03 Janssen Pharmaceutica Nv Heteroaryl linked quinolinyl modulators of RORgammat
CA2927182A1 (en) * 2013-10-15 2015-04-23 Janssen Pharmaceutica Nv Quinolinyl modulators of ror.gamma.t
US9403816B2 (en) 2013-10-15 2016-08-02 Janssen Pharmaceutica Nv Phenyl linked quinolinyl modulators of RORγt
US9458150B2 (en) 2013-11-08 2016-10-04 Rutgers, The State University Of New Jersey Antimicrobial agents
WO2017147316A1 (en) 2016-02-25 2017-08-31 Taxis Pharmaceuticals, Inc. Synthetic processes and intermediates
CN110891566B (zh) 2017-03-30 2023-12-19 塔克西斯医药股份有限公司 合成方法和合成中间体

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965572A (en) * 1996-10-28 1999-10-12 The United States Of America As Respresented By The Secretary Of The Army Methods for treating antibiotic-resistant infections
AU757059B2 (en) * 1997-06-19 2003-01-30 Sepracor, Inc. Quinoline-indole antimicrobial agents, uses and compositions related thereto
US6103905A (en) 1997-06-19 2000-08-15 Sepracor, Inc. Quinoline-indole antimicrobial agents, uses and compositions related thereto
AU2717899A (en) * 1998-01-26 1999-08-09 Smithkline Beecham Plc Quinoline derivatives as antibacterials
SI1527050T1 (sl) * 2002-07-25 2010-08-31 Janssen Pharmaceutica Nv Kinolinski derivati in njihova uporaba kot mikobakterijski inhibitorji
BRPI0507076B8 (pt) * 2004-01-23 2021-05-25 Janssen Pharmaceutica Nv quinolinas substituídas, seu processo de preparação, composição farmacêutica que as compreende e seu uso como inibidores micobacterianos

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO341242B1 (no) * 2005-08-03 2017-09-25 Janssen Pharmaceutica Nv Kinolinderivater som antibakterielle midler

Also Published As

Publication number Publication date
ES2306098T3 (es) 2008-11-01
EP1713776B1 (en) 2008-05-14
JP4919810B2 (ja) 2012-04-18
EA011572B1 (ru) 2009-04-28
CA2554049C (en) 2012-12-18
NO337253B1 (no) 2016-02-22
HK1099297A1 (en) 2007-08-10
KR101160183B1 (ko) 2012-06-26
AP2006003705A0 (en) 2006-08-31
IL177101A (en) 2012-01-31
EA200601391A1 (ru) 2006-12-29
CA2554049A1 (en) 2005-08-18
AP2321A (en) 2011-11-16
KR20070004597A (ko) 2007-01-09
AU2005210036B2 (en) 2010-12-23
EP1713776A1 (en) 2006-10-25
ATE395336T1 (de) 2008-05-15
US7790894B2 (en) 2010-09-07
BRPI0507312A (pt) 2007-06-26
EA011572B9 (ru) 2018-01-31
ZA200606291B (en) 2008-02-27
CN1910154A (zh) 2007-02-07
NZ547614A (en) 2009-04-30
IL177101A0 (en) 2006-12-10
CN1910154B (zh) 2011-08-17
JP2007519687A (ja) 2007-07-19
DE602005006744D1 (de) 2008-06-26
UA83875C2 (ru) 2008-08-26
US20070299106A1 (en) 2007-12-27
MXPA06008596A (es) 2006-08-28
WO2005075428A1 (en) 2005-08-18
AU2005210036A1 (en) 2005-08-18

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