NO20063866L - 1,3,5-trisubstituerte 4,5-di hydro-1 H-pyrazolderivater med CB1-antagonistisk aktivitet. - Google Patents

1,3,5-trisubstituerte 4,5-di hydro-1 H-pyrazolderivater med CB1-antagonistisk aktivitet.

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Publication number
NO20063866L
NO20063866L NO20063866A NO20063866A NO20063866L NO 20063866 L NO20063866 L NO 20063866L NO 20063866 A NO20063866 A NO 20063866A NO 20063866 A NO20063866 A NO 20063866A NO 20063866 L NO20063866 L NO 20063866L
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Norway
Prior art keywords
pyrazole derivatives
trisubstituted
hydro
antagonistic activity
compounds
Prior art date
Application number
NO20063866A
Other languages
English (en)
Inventor
Cornelis Gerrit Kruse
Josephus H M Lange
Herman H Van Stuivenberg
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Solvay Pharm Bv
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Publication date
Application filed by Solvay Pharm Bv filed Critical Solvay Pharm Bv
Publication of NO20063866L publication Critical patent/NO20063866L/no

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    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
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Abstract

der symbolene har betydningene som er angitt i beskrivelsen. Den foreliggende oppfinnelsen vedrører 1,3,5-trisubstituerte 4,5-dihydro-lH-pyrazol derivater som CB1-antagonister, fremgangsmåte for fremstilling av disse forbindelsene og nye mellomprodukter som er nyttige i syntesen av de nevnte pyrazolderivatene. Oppfinnelsen vedrører også anvendelsen av en forbindelse som her er beskrevet for fremstilling av et medikament som gir en fordelaktig effekt. Forbindelsene har den generelle formel (I)
NO20063866A 2004-01-30 2006-08-30 1,3,5-trisubstituerte 4,5-di hydro-1 H-pyrazolderivater med CB1-antagonistisk aktivitet. NO20063866L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53998304P 2004-01-30 2004-01-30
EP04100338 2004-01-30
PCT/EP2005/050339 WO2005074920A1 (en) 2004-01-30 2005-01-27 1,3,5-trisubstituted 4,5-dihydro-1h-pyrazole derivatives having cb1-antagonistic activity

Publications (1)

Publication Number Publication Date
NO20063866L true NO20063866L (no) 2006-10-27

Family

ID=34839806

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20063866A NO20063866L (no) 2004-01-30 2006-08-30 1,3,5-trisubstituerte 4,5-di hydro-1 H-pyrazolderivater med CB1-antagonistisk aktivitet.

Country Status (20)

Country Link
EP (1) EP1713475B1 (no)
JP (1) JP4693787B2 (no)
KR (1) KR20060131861A (no)
CN (1) CN100563651C (no)
AT (1) ATE402697T1 (no)
AU (1) AU2005210163B2 (no)
BR (1) BRPI0507005A (no)
CA (1) CA2552940A1 (no)
DE (1) DE602005008555D1 (no)
DK (1) DK1713475T3 (no)
ES (1) ES2311972T3 (no)
HR (1) HRP20080549T3 (no)
IL (1) IL176547A (no)
MX (1) MXPA06008593A (no)
NO (1) NO20063866L (no)
PL (1) PL1713475T3 (no)
PT (1) PT1713475E (no)
RU (1) RU2360904C2 (no)
SI (1) SI1713475T1 (no)
WO (1) WO2005074920A1 (no)

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EP1743890A1 (en) * 2005-07-15 2007-01-17 Laboratorios Del Dr. Esteve, S.A. 4,5-Dihydro-1H-pyrazole derivatives, their preparation and use as medicaments
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WO2007017124A1 (en) * 2005-07-29 2007-02-15 Laboratorios Del Dr. Esteve, S.A. Amorphous phase of a substituted pyrazoline, its preparation and use as medicament
WO2007017126A2 (en) * 2005-07-29 2007-02-15 Laboratorios Del Dr. Esteve, S.A. POLYMORPH OF N-PIPERIDINYL-5- (4-CHLOROPHENYL) -1- (2, 4-DICHLOROPHENYL) -4, 5-DIHYDRO-lH-PYRAZOLE- 3 -CARBOXAMIDE AND ITS USE AS A CAMNABINOID RECEPTOR MODULATOR
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JP2010530367A (ja) * 2007-06-15 2010-09-09 ソルベイ・フアーマシユーチカルズ・ベー・ブイ カンナビノイドｃｂ１受容体モジュレーターとしての４，５−ジヒドロ−（１ｈ）−ピラゾール誘導体
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AU2015255765A1 (en) * 2014-05-09 2016-11-24 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Pyrazole derivatives and their use as cannabinoid receptor mediators
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CN1913885A (zh) 2007-02-14
ATE402697T1 (de) 2008-08-15
CN100563651C (zh) 2009-12-02
DE602005008555D1 (de) 2008-09-11
RU2360904C2 (ru) 2009-07-10
AU2005210163B2 (en) 2010-05-13
SI1713475T1 (sl) 2008-12-31
HK1099688A1 (en) 2007-08-24
WO2005074920A1 (en) 2005-08-18
MXPA06008593A (es) 2006-08-28
DK1713475T3 (da) 2008-12-01
IL176547A (en) 2010-06-30
CA2552940A1 (en) 2005-08-18
ES2311972T3 (es) 2009-02-16
BRPI0507005A (pt) 2007-06-05
KR20060131861A (ko) 2006-12-20
PT1713475E (pt) 2008-11-10
AU2005210163A1 (en) 2005-08-18
IL176547A0 (en) 2006-10-31
EP1713475B1 (en) 2008-07-30
RU2006131132A (ru) 2008-03-10
JP2007519686A (ja) 2007-07-19
EP1713475A1 (en) 2006-10-25
HRP20080549T3 (en) 2008-11-30
PL1713475T3 (pl) 2009-03-31

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