NO20064295L - Bruk av metylenamidderivater i kardiovaskulaere lidelser - Google Patents

Bruk av metylenamidderivater i kardiovaskulaere lidelser

Info

Publication number
NO20064295L
NO20064295L NO20064295A NO20064295A NO20064295L NO 20064295 L NO20064295 L NO 20064295L NO 20064295 A NO20064295 A NO 20064295A NO 20064295 A NO20064295 A NO 20064295A NO 20064295 L NO20064295 L NO 20064295L
Authority
NO
Norway
Prior art keywords
cardiovascular disorders
derivatives
methylenamide
prevention
formula
Prior art date
Application number
NO20064295A
Other languages
English (en)
Inventor
Rob Hooft Van Huijsduijnen
Vincent Richard
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Publication of NO20064295L publication Critical patent/NO20064295L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Den foreliggende oppfinnelsen gjelder anvendelsen av substituerte metylenamidderivater med formel (I) for behandling og/eller forebygging av kardiovaskulære lidelser som koronar obstruksjon og hjertesvikt. Spesielt gjelder den foreliggende oppfinnelsen anvendelsen av substituerte metylenamidderivater med formel (I) spesielt for behandling og/eller forebygging av endotelisk dysfunksjon ved hjertesvikt.
NO20064295A 2004-02-27 2006-09-22 Bruk av metylenamidderivater i kardiovaskulaere lidelser NO20064295L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04100778 2004-02-27
PCT/EP2005/050823 WO2005082347A1 (en) 2004-02-27 2005-02-25 Use of methylene amide derivatives in cardiovascular disorders

Publications (1)

Publication Number Publication Date
NO20064295L true NO20064295L (no) 2006-09-22

Family

ID=34896106

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20064295A NO20064295L (no) 2004-02-27 2006-09-22 Bruk av metylenamidderivater i kardiovaskulaere lidelser

Country Status (23)

Country Link
US (1) US20070185118A1 (no)
EP (1) EP1732534B1 (no)
JP (1) JP5001138B2 (no)
KR (1) KR101188940B1 (no)
CN (1) CN1933827B (no)
AT (1) ATE401877T1 (no)
AU (1) AU2005216649B2 (no)
BR (1) BRPI0508080A (no)
CA (1) CA2554919C (no)
CY (1) CY1108252T1 (no)
DE (1) DE602005008412D1 (no)
DK (1) DK1732534T3 (no)
EA (1) EA011811B1 (no)
ES (1) ES2308458T3 (no)
HR (1) HRP20080367T3 (no)
IL (1) IL177494A (no)
NO (1) NO20064295L (no)
PL (1) PL1732534T3 (no)
PT (1) PT1732534E (no)
RS (1) RS50596B (no)
SI (1) SI1732534T1 (no)
UA (1) UA84453C2 (no)
WO (1) WO2005082347A1 (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA04007253A (es) * 2002-01-29 2004-10-29 Applied Research Systems Derivados de metilenamidas sustituidos como moduladores de proteina tirosina fosfatasas (ptp).
ES2337150T3 (es) 2003-07-21 2010-04-21 Merck Serono Sa Alquinilaril carboxamidas.
US7884234B2 (en) 2006-10-12 2011-02-08 Institute Of Medicinal Molecular Design, Inc. N-phenyloxamide derivatives
US8633245B2 (en) * 2008-04-11 2014-01-21 Institute Of Medicinal Molecular Design, Inc. PAI-1 inhibitor
CN103764793B (zh) 2011-08-29 2016-09-14 提克纳有限责任公司 高流动液晶聚合物组合物
US9045685B2 (en) 2011-08-29 2015-06-02 Ticona Llc Cast molded parts formed from a liquid crystalline polymer
TW201319118A (zh) 2011-08-29 2013-05-16 Ticona Llc 低熔融黏度液晶聚合物之熔融聚合
KR20140057629A (ko) 2011-08-29 2014-05-13 티코나 엘엘씨 방향족 아마이드 화합물
WO2013032974A1 (en) 2011-08-29 2013-03-07 Ticona Llc Solid-state polymerization of a liquid crystalline polymer
WO2013032975A1 (en) 2011-08-29 2013-03-07 Ticona Llc Thermotropic liquid crystalline polymer with improved low shear viscosity
WO2013032971A1 (en) 2011-08-29 2013-03-07 Ticona Llc Melt-extruded substrate for use in thermoformed articles
US8906258B2 (en) 2011-08-29 2014-12-09 Ticona Llc Heat-resistant liquid crystalline polymer composition having a low melting temperature
US9096794B2 (en) 2011-08-29 2015-08-04 Ticona Llc High flow liquid crystalline polymer composition
US20150337212A1 (en) 2012-12-17 2015-11-26 Shell Oil Company Integrated gas-to-liquids condensate process
WO2014130275A2 (en) 2013-02-22 2014-08-28 Ticona Llc High performance polymer composition with improved flow properties
CN113912988A (zh) 2013-06-07 2022-01-11 提克纳有限责任公司 高强度热致液晶聚合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1214324B1 (en) * 1999-09-10 2006-06-14 Novo Nordisk A/S MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases)
US6627767B2 (en) * 2000-08-29 2003-09-30 Abbott Laboratories Amino(oxo) acetic acid protein tyrosine phosphatase inhibitors
DE10117823A1 (de) * 2001-04-10 2002-10-17 Merck Patent Gmbh Oxalsäurederivate
US20030055058A1 (en) * 2001-06-07 2003-03-20 Wyeth Combination of a PTPase inhibitor and an ACE inhibitor
WO2002098408A1 (en) * 2001-06-07 2002-12-12 Wyeth Ptpase inhibitors for improving cardiovascular risk profile
MXPA04007253A (es) * 2002-01-29 2004-10-29 Applied Research Systems Derivados de metilenamidas sustituidos como moduladores de proteina tirosina fosfatasas (ptp).

Also Published As

Publication number Publication date
CY1108252T1 (el) 2014-02-12
RS50596B (sr) 2010-05-07
EP1732534B1 (en) 2008-07-23
IL177494A0 (en) 2006-12-31
DE602005008412D1 (de) 2008-09-04
DK1732534T3 (da) 2008-11-17
JP2007524701A (ja) 2007-08-30
BRPI0508080A (pt) 2007-07-17
PT1732534E (pt) 2008-08-08
CN1933827A (zh) 2007-03-21
SI1732534T1 (sl) 2008-10-31
EP1732534A1 (en) 2006-12-20
UA84453C2 (ru) 2008-10-27
JP5001138B2 (ja) 2012-08-15
WO2005082347A1 (en) 2005-09-09
CA2554919C (en) 2013-04-16
PL1732534T3 (pl) 2008-12-31
ES2308458T3 (es) 2008-12-01
AU2005216649A1 (en) 2005-09-09
KR101188940B1 (ko) 2012-10-08
HK1098073A1 (en) 2007-07-13
HRP20080367T3 (en) 2008-09-30
EA011811B1 (ru) 2009-06-30
KR20060129066A (ko) 2006-12-14
EA200601511A1 (ru) 2007-02-27
IL177494A (en) 2011-06-30
CA2554919A1 (en) 2005-09-09
CN1933827B (zh) 2011-07-27
ATE401877T1 (de) 2008-08-15
AU2005216649B2 (en) 2010-09-09
US20070185118A1 (en) 2007-08-09

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