NO20065084L - Interferon-alfa polypeptider og konjugater - Google Patents
Interferon-alfa polypeptider og konjugaterInfo
- Publication number
- NO20065084L NO20065084L NO20065084A NO20065084A NO20065084L NO 20065084 L NO20065084 L NO 20065084L NO 20065084 A NO20065084 A NO 20065084A NO 20065084 A NO20065084 A NO 20065084A NO 20065084 L NO20065084 L NO 20065084L
- Authority
- NO
- Norway
- Prior art keywords
- conjugates
- polypeptides
- nucleic acids
- interferon
- alpha polypeptides
- Prior art date
Links
- 102000006992 Interferon-alpha Human genes 0.000 title abstract 2
- 108010047761 Interferon-alpha Proteins 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 5
- 108020004707 nucleic acids Proteins 0.000 abstract 5
- 150000007523 nucleic acids Chemical class 0.000 abstract 5
- 229920001184 polypeptide Polymers 0.000 abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 5
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biotechnology (AREA)
- AIDS & HIV (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57250404P | 2004-05-19 | 2004-05-19 | |
| PCT/US2005/017471 WO2005113592A2 (en) | 2004-05-19 | 2005-05-18 | Interferon-alpha polypeptides and conjugates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20065084L true NO20065084L (no) | 2006-12-01 |
Family
ID=35428915
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20065084A NO20065084L (no) | 2004-05-19 | 2006-11-03 | Interferon-alfa polypeptider og konjugater |
Country Status (14)
| Country | Link |
|---|---|
| US (9) | US7318918B2 (pt) |
| EP (1) | EP1753779A2 (pt) |
| JP (1) | JP2008507298A (pt) |
| CN (1) | CN101115769A (pt) |
| AR (1) | AR049177A1 (pt) |
| AU (1) | AU2005245918A1 (pt) |
| BR (1) | BRPI0511196A (pt) |
| CA (1) | CA2566247A1 (pt) |
| IL (1) | IL178470A0 (pt) |
| MX (1) | MXPA06013412A (pt) |
| NO (1) | NO20065084L (pt) |
| RU (1) | RU2006145020A (pt) |
| TW (1) | TW200611910A (pt) |
| WO (1) | WO2005113592A2 (pt) |
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| JP2002537762A (ja) | 1999-01-05 | 2002-11-12 | トラスティーズ オブ ボストン ユニバーシティ | 改良型核酸クローニング |
| US20040005673A1 (en) | 2001-06-29 | 2004-01-08 | Kevin Jarrell | System for manipulating nucleic acids |
| WO2002008408A2 (en) * | 2000-07-21 | 2002-01-31 | Trustees Of Boston University | Modular vector systems |
| US7435562B2 (en) * | 2000-07-21 | 2008-10-14 | Modular Genetics, Inc. | Modular vector systems |
| EP1759521B1 (en) * | 2004-05-12 | 2016-06-29 | Synchronoss Technologies, Inc. | Advanced contact identification system |
| US7485423B2 (en) | 2004-11-11 | 2009-02-03 | Modular Genetics, Inc. | Ladder assembly and system for generating diversity |
| US20080124302A1 (en) * | 2005-03-09 | 2008-05-29 | Guangwen Wei | Uses of Recombinant Super-Compound Interferons |
| MX2007014524A (es) | 2005-05-18 | 2008-02-07 | Maxygen Inc | Polipeptidos desarrollados de interferon-alfa. |
| AR078117A1 (es) * | 2006-06-20 | 2011-10-19 | Protech Pharma S A | Una muteina recombinante del interferon alfa humano glicosilado, un gen que codifica para dicha muteina, un metodo de produccion de dicho gen, un metodo para obtener una celula eucariota productora de dicha muteina, un metodo para producir dicha muteina, un procedimiento para purificar dicha muteina |
| US20080014616A1 (en) * | 2006-07-11 | 2008-01-17 | Kevin Jarrell | Methods of introducing targeted diversity into nucleic acid molecules |
| WO2008013082A1 (en) * | 2006-07-25 | 2008-01-31 | Galpharma Co., Ltd. | Galectin 9-polymer conjugate |
| US7808342B2 (en) * | 2006-10-02 | 2010-10-05 | Skyworks Solutions, Inc. | Harmonic phase tuning filter for RF switches |
| US11535673B2 (en) | 2007-04-05 | 2022-12-27 | President and Fellows of Harvard CoHege | Chimeric activators: quantitatively designed protein therapeutics and uses thereof |
| US7625555B2 (en) | 2007-06-18 | 2009-12-01 | Novagen Holding Corporation | Recombinant human interferon-like proteins |
| WO2009006579A1 (en) * | 2007-07-05 | 2009-01-08 | Pharmaessentia Corp. | Peptide-polymer conjugates |
| EP2195338B1 (en) * | 2007-10-01 | 2013-12-25 | Pharmaessentia Corp. | N-terminal modified interferon-alpha |
| AU2009204998B2 (en) | 2008-01-18 | 2014-03-27 | F. Hoffmann-La Roche Ag | Purification of non-glycosylated proteins |
| US7954022B2 (en) * | 2008-01-30 | 2011-05-31 | Alcatel-Lucent Usa Inc. | Apparatus and method for controlling dynamic modification of a scan path |
| TW201032826A (en) * | 2008-11-17 | 2010-09-16 | Genentech Inc | Method and formulation for reducing aggregation of a macromolecule under physiological conditions |
| WO2010087994A2 (en) | 2009-01-30 | 2010-08-05 | Whitehead Institute For Biomedical Research | Methods for ligation and uses thereof |
| US9944688B2 (en) | 2011-06-02 | 2018-04-17 | Hanmi Science Co., Ltd. | Non-peptidyl polymer-insulin multimer and method for producing the same |
| US10081684B2 (en) | 2011-06-28 | 2018-09-25 | Whitehead Institute For Biomedical Research | Using sortases to install click chemistry handles for protein ligation |
| CN102358897B (zh) * | 2011-10-31 | 2013-02-13 | 北京三元基因工程有限公司 | 重组人寡腺苷酸合成酶-1的制备方法 |
| US10308697B2 (en) | 2014-04-30 | 2019-06-04 | President And Fellows Of Harvard College | Fusion proteins for treating cancer and related methods |
| ES2630106T3 (es) * | 2014-10-07 | 2017-08-18 | Cyprumed Gmbh | Formulaciones farmacéuticas para la administración oral de fármacos peptídicos o proteicos |
| EP3397287B8 (en) | 2015-12-30 | 2025-07-23 | F. Hoffmann-La Roche AG | Formulations with reduced degradation of polysorbate |
| CN116769054A (zh) * | 2016-02-05 | 2023-09-19 | 奥里尼斯生物科学私人有限公司 | 双特异性信号传导剂及其用途 |
| RU2650755C1 (ru) * | 2017-05-24 | 2018-04-17 | Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства России (ФГБУ "ГНЦ Институт иммунологии" ФМБА России) | Способ очистки лекарственного средства пролонгированного действия на основе рекомбинантного аналога интерферона альфа-17 для лечения вирусного гепатита С |
| JP2023511946A (ja) * | 2020-01-24 | 2023-03-23 | アルカームス ファーマ アイルランド リミテッド | 精製方法 |
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| US6610830B1 (en) * | 1980-07-01 | 2003-08-26 | Hoffman-La Roche Inc. | Microbial production of mature human leukocyte interferons |
| US4414150A (en) * | 1980-11-10 | 1983-11-08 | Genentech, Inc. | Hybrid human leukocyte interferons |
| ES506955A0 (es) | 1980-11-10 | 1983-02-01 | Genentech Inc | Un procedimiento para producir un polipeptido antiviral. |
| IT1167610B (it) | 1982-01-19 | 1987-05-13 | Cetus Corp | Interfreron ibrido multiclasse, composizione farmaceutica che lo contiene e procedimento di produzione |
| US6936694B1 (en) * | 1982-05-06 | 2005-08-30 | Intermune, Inc. | Manufacture and expression of large structural genes |
| JPS60152058A (ja) * | 1984-01-20 | 1985-08-10 | Toshiba Corp | 半導体記憶装置 |
| DE3685996T2 (de) * | 1985-06-11 | 1993-01-14 | Ciba Geigy Ag | Hybrid-interferone. |
| US4695626A (en) * | 1986-07-29 | 1987-09-22 | Pfizer Inc. | 1-aza-4,5-dithiabicyclo [4.2.0] oct-2-en-8-one-2 carboxylate esters |
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| WO1992006707A1 (en) | 1990-10-17 | 1992-04-30 | Amgen Inc. | Methods and compositions for the treatment of cell proliferation disorders |
| US5595732A (en) * | 1991-03-25 | 1997-01-21 | Hoffmann-La Roche Inc. | Polyethylene-protein conjugates |
| US5382657A (en) * | 1992-08-26 | 1995-01-17 | Hoffmann-La Roche Inc. | Peg-interferon conjugates |
| US5574138A (en) * | 1993-03-08 | 1996-11-12 | Immunex Corporation | Epithelium-derived T-cell factor |
| US6335160B1 (en) * | 1995-02-17 | 2002-01-01 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
| JP4001379B2 (ja) | 1994-03-07 | 2007-10-31 | インペリアル カレッジ オブ サイエンス,テクノロジー アンド メディシン | ウィルス感染を治療する薬剤の調製におけるインターフェロンのサブタイプの使用 |
| US5824784A (en) | 1994-10-12 | 1998-10-20 | Amgen Inc. | N-terminally chemically modified protein compositions and methods |
| TW517067B (en) * | 1996-05-31 | 2003-01-11 | Hoffmann La Roche | Interferon conjugates |
| CN1269805A (zh) | 1997-07-14 | 2000-10-11 | 博尔德生物技术公司 | 生长激素和相关蛋白的衍生物 |
| JP2002534119A (ja) | 1999-01-14 | 2002-10-15 | ボルダー バイオテクノロジー, インコーポレイテッド | 自由システイン残基を有するタンパク質の生産方法 |
| AU3725600A (en) * | 1999-03-02 | 2000-09-21 | Maxygen, Inc. | Surrogate orphan ligands for orphan receptors |
| KR20020018197A (ko) | 1999-05-19 | 2002-03-07 | 추후보정 | Fc 융합 단백질로서의 인터페론-알파 단백질의 발현 및분비 |
| US20040002474A1 (en) * | 1999-10-07 | 2004-01-01 | Maxygen Inc. | IFN-alpha homologues |
| CA2385045A1 (en) * | 1999-10-07 | 2001-04-12 | Maxygen, Inc. | Ifn-alpha homologues |
| SK8292002A3 (en) * | 1999-11-12 | 2002-12-03 | Maxygen Holdings Ltd | A conjugate exhibiting interferon gamma activity, nucleotide sequence encoding for a polypeptide fraction of conjugate, an expression vector and a host cell containing nucleotide sequence, pharmaceutical composition comprising the same and use thereof |
| IL152804A0 (en) | 2000-05-16 | 2003-06-24 | Bolder Biotechnology Inc | Methods for refolding proteins containing free cysteine residues |
| WO2002044197A2 (en) | 2000-12-01 | 2002-06-06 | Fish Eleanor N | Cytokine receptor binding peptides |
| KR100459105B1 (ko) | 2001-02-15 | 2004-12-03 | 선바이오(주) | 변형된 인터페론-알파 2a 및 2b, 그리고 이들과 PEG유도체와의 배합체 |
| AU2003293668A1 (en) | 2002-11-15 | 2004-06-15 | F. Hoffmann-La Roche Ag | Positional isomers of peg ifn alpha 2a |
| US20040219131A1 (en) * | 2002-11-18 | 2004-11-04 | Maxygen, Inc. | Interferon-alpha polypeptides and conjugates |
-
2005
- 2005-05-18 CA CA002566247A patent/CA2566247A1/en not_active Abandoned
- 2005-05-18 EP EP05751765A patent/EP1753779A2/en not_active Withdrawn
- 2005-05-18 AU AU2005245918A patent/AU2005245918A1/en not_active Abandoned
- 2005-05-18 BR BRPI0511196-0A patent/BRPI0511196A/pt not_active Application Discontinuation
- 2005-05-18 RU RU2006145020/04A patent/RU2006145020A/ru unknown
- 2005-05-18 JP JP2007527427A patent/JP2008507298A/ja active Pending
- 2005-05-18 TW TW094116107A patent/TW200611910A/zh unknown
- 2005-05-18 CN CNA2005800241473A patent/CN101115769A/zh active Pending
- 2005-05-18 US US11/132,722 patent/US7318918B2/en not_active Expired - Fee Related
- 2005-05-18 MX MXPA06013412A patent/MXPA06013412A/es unknown
- 2005-05-18 WO PCT/US2005/017471 patent/WO2005113592A2/en not_active Ceased
- 2005-05-19 AR ARP050102059A patent/AR049177A1/es unknown
-
2006
- 2006-09-13 US US11/531,570 patent/US20070020734A1/en not_active Abandoned
- 2006-09-13 US US11/531,557 patent/US7531324B2/en not_active Expired - Fee Related
- 2006-09-13 US US11/531,531 patent/US7531630B2/en not_active Expired - Fee Related
- 2006-09-14 US US11/532,024 patent/US20070225204A1/en not_active Abandoned
- 2006-09-14 US US11/532,045 patent/US20070225205A1/en not_active Abandoned
- 2006-10-05 IL IL178470A patent/IL178470A0/en unknown
- 2006-11-03 NO NO20065084A patent/NO20065084L/no unknown
-
2007
- 2007-05-04 US US11/744,424 patent/US7541436B2/en not_active Expired - Fee Related
- 2007-08-14 US US11/838,730 patent/US7541163B2/en not_active Expired - Fee Related
- 2007-08-15 US US11/839,493 patent/US7537755B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AR049177A1 (es) | 2006-07-05 |
| US20050266465A1 (en) | 2005-12-01 |
| US7541436B2 (en) | 2009-06-02 |
| JP2008507298A (ja) | 2008-03-13 |
| TW200611910A (en) | 2006-04-16 |
| US7541163B2 (en) | 2009-06-02 |
| US20070225204A1 (en) | 2007-09-27 |
| US7318918B2 (en) | 2008-01-15 |
| US7537755B2 (en) | 2009-05-26 |
| WO2005113592A3 (en) | 2006-04-06 |
| US20080076710A1 (en) | 2008-03-27 |
| WO2005113592A2 (en) | 2005-12-01 |
| EP1753779A2 (en) | 2007-02-21 |
| US20070020235A1 (en) | 2007-01-25 |
| US20080031853A1 (en) | 2008-02-07 |
| US20070020734A1 (en) | 2007-01-25 |
| CA2566247A1 (en) | 2005-12-01 |
| US7531630B2 (en) | 2009-05-12 |
| MXPA06013412A (es) | 2007-01-23 |
| US20070025966A1 (en) | 2007-02-01 |
| BRPI0511196A (pt) | 2007-12-04 |
| US20080171363A1 (en) | 2008-07-17 |
| CN101115769A (zh) | 2008-01-30 |
| AU2005245918A1 (en) | 2005-12-01 |
| US20070225205A1 (en) | 2007-09-27 |
| RU2006145020A (ru) | 2008-06-27 |
| IL178470A0 (en) | 2007-02-11 |
| US7531324B2 (en) | 2009-05-12 |
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