NO20070157L - Substituerte diketopiperaziner som oksytocinantagonister - Google Patents

Substituerte diketopiperaziner som oksytocinantagonister

Info

Publication number
NO20070157L
NO20070157L NO20070157A NO20070157A NO20070157L NO 20070157 L NO20070157 L NO 20070157L NO 20070157 A NO20070157 A NO 20070157A NO 20070157 A NO20070157 A NO 20070157A NO 20070157 L NO20070157 L NO 20070157L
Authority
NO
Norway
Prior art keywords
oxytocin antagonists
methyl
substituted diketopiperazines
diketopiperazines
substituted
Prior art date
Application number
NO20070157A
Other languages
English (en)
Inventor
Alan David Borthwick
Steven Leslie Sollis
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of NO20070157L publication Critical patent/NO20070157L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Det er beskrevet forbindelser av formel (IA) hvor R1 er 2-indanyl, R2 er 1-metylpropyl, R3 er 1-metyl indazol-5-yl, R4 betyr metyl og R5 betyr hydrogen eller metyl, og farmasøytisk akseptable derivater derav, så vel som fremgangsmåter for deres fremstilling, farmasøytiske preparater inneholdende disse og anvendelse av disse innenfor medisin, spesielt anvendelse som oksytocinantagonister.
NO20070157A 2004-06-23 2007-01-09 Substituerte diketopiperaziner som oksytocinantagonister NO20070157L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0414092.7A GB0414092D0 (en) 2004-06-23 2004-06-23 Novel compounds
PCT/EP2005/006761 WO2006000400A1 (en) 2004-06-23 2005-06-21 Substituted diketopiperazines as oxytocin antagonists

Publications (1)

Publication Number Publication Date
NO20070157L true NO20070157L (no) 2007-01-23

Family

ID=32800052

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20070157A NO20070157L (no) 2004-06-23 2007-01-09 Substituerte diketopiperaziner som oksytocinantagonister

Country Status (18)

Country Link
US (1) US20070208031A1 (no)
EP (1) EP1758893A1 (no)
JP (1) JP2008503535A (no)
CN (1) CN1989130A (no)
AR (1) AR049651A1 (no)
AU (1) AU2005256471A1 (no)
BR (1) BRPI0512359A (no)
CA (1) CA2571529A1 (no)
GB (1) GB0414092D0 (no)
IL (1) IL179912A0 (no)
MA (1) MA28698B1 (no)
MX (1) MXPA06014544A (no)
NO (1) NO20070157L (no)
PE (1) PE20060533A1 (no)
RU (1) RU2007102272A (no)
TW (1) TW200616635A (no)
WO (1) WO2006000400A1 (no)
ZA (1) ZA200610121B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2641806B1 (fr) * 1989-01-16 1992-05-07 Diffusion Rech Tech Financ Procede de stabilisation d'une aire de terrain meuble
GB0130677D0 (en) * 2001-12-21 2002-02-06 Glaxo Group Ltd Medicaments and novel compounds
GB0314738D0 (en) 2003-06-24 2003-07-30 Glaxo Group Ltd Novel compounds
GB0414093D0 (en) 2004-06-23 2004-07-28 Glaxo Group Ltd Novel compounds
GB0414100D0 (en) * 2004-06-23 2004-07-28 Glaxo Group Ltd Novel compounds
US7919581B2 (en) * 2007-07-31 2011-04-05 Burnham Institute For Medical Research Bi-dentate compounds as kinase inhibitors
US20100038143A1 (en) * 2008-08-14 2010-02-18 George Alexander Burnett Drill cuttings treatment systems
JP2013509391A (ja) 2009-10-30 2013-03-14 グラクソ グループ リミテッド （３ｒ，６ｒ）−３−（２，３−ジヒドロ−１ｈ−インデン−２−イル）−１−［（１ｒ）−１−（２，６−ジメチル−３−ピリジニル）−２−（４−モルホリニル）−２−オキソエチル］−６−［（１ｓ）−１−メチルプロピル］−２，５−ピペラジンジオンの新規結晶性形態
CN109305969B (zh) * 2017-07-27 2023-03-10 江苏恒瑞医药股份有限公司 哌嗪-2,5-二酮类衍生物、其制备方法及其在医药上的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0130677D0 (en) * 2001-12-21 2002-02-06 Glaxo Group Ltd Medicaments and novel compounds
GB0414100D0 (en) * 2004-06-23 2004-07-28 Glaxo Group Ltd Novel compounds

Also Published As

Publication number Publication date
ZA200610121B (en) 2008-08-27
EP1758893A1 (en) 2007-03-07
AR049651A1 (es) 2006-08-23
US20070208031A1 (en) 2007-09-06
AU2005256471A1 (en) 2006-01-05
JP2008503535A (ja) 2008-02-07
CA2571529A1 (en) 2006-01-05
RU2007102272A (ru) 2008-07-27
BRPI0512359A (pt) 2008-03-04
GB0414092D0 (en) 2004-07-28
CN1989130A (zh) 2007-06-27
IL179912A0 (en) 2007-05-15
TW200616635A (en) 2006-06-01
MXPA06014544A (es) 2007-03-12
WO2006000400A1 (en) 2006-01-05
PE20060533A1 (es) 2006-09-03
MA28698B1 (fr) 2007-06-01

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application