NO20064166L - Utvalgte CGRP-antagonister, deres fremstilling og deres anvendelse som medikanmenter - Google Patents

Utvalgte CGRP-antagonister, deres fremstilling og deres anvendelse som medikanmenter

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Publication number
NO20064166L
NO20064166L NO20064166A NO20064166A NO20064166L NO 20064166 L NO20064166 L NO 20064166L NO 20064166 A NO20064166 A NO 20064166A NO 20064166 A NO20064166 A NO 20064166A NO 20064166 L NO20064166 L NO 20064166L
Authority
NO
Norway
Prior art keywords
preparation
medicaments
cgrp antagonists
salts
selected cgrp
Prior art date
Application number
NO20064166A
Other languages
English (en)
Inventor
Henri Nico Doods
Klaus Rudolf
Stephan Georg Mueller
Dirk Stenkamp
Philipp Lustenberger
Kirsten Arndt
Alexander Dreyer
Gerhard Schaenzle
Marco Santagostino
Fabio Paleari
Original Assignee
Boehringer Ingelheim Int
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Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of NO20064166L publication Critical patent/NO20064166L/no

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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • General Chemical & Material Sciences (AREA)
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  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Addiction (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
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  • Vascular Medicine (AREA)
  • Communicable Diseases (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychiatry (AREA)

Abstract

Det beskrives CGRP-antagonister med den generelle formel (I) hvor A, X, D, E, G, M, Q og R1 til R3 er som definert i krav 1, deres tautomerer, isomerer, diastereomerer, enantiomerer, hydrater, blandinger og deres salter, samt hydratene av saltene, særlig deres fysiologisk akseptable salter med uorganiske eller organiske syrer, medikamenter som inneholder disse forbindelsene, deres anvendelse og fremgangsmåter for deres fremstilling.
NO20064166A 2004-03-29 2006-09-14 Utvalgte CGRP-antagonister, deres fremstilling og deres anvendelse som medikanmenter NO20064166L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004015723A DE102004015723A1 (de) 2004-03-29 2004-03-29 Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
PCT/EP2005/003094 WO2005092880A1 (de) 2004-03-29 2005-03-23 Ausgewählte cgrp-antagonisten, verfahren zu deren herstellung sowie deren verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
NO20064166L true NO20064166L (no) 2006-10-25

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
NO20064166A NO20064166L (no) 2004-03-29 2006-09-14 Utvalgte CGRP-antagonister, deres fremstilling og deres anvendelse som medikanmenter

Country Status (32)

Country Link
US (3) US7479488B2 (no)
EP (2) EP1732917B8 (no)
JP (2) JP4796567B2 (no)
KR (1) KR20070007867A (no)
CN (1) CN1976916A (no)
AR (2) AR049625A1 (no)
AT (2) ATE437868T1 (no)
AU (1) AU2005225539A1 (no)
BR (2) BRPI0509368A (no)
CA (1) CA2558889A1 (no)
CY (2) CY1108744T1 (no)
DE (2) DE102004015723A1 (no)
DK (1) DK1732917T3 (no)
EA (1) EA012111B1 (no)
EC (1) ECSP066898A (no)
ES (1) ES2330865T3 (no)
HR (1) HRP20090457T1 (no)
IL (2) IL178334A0 (no)
MX (1) MX2007011526A (no)
MY (1) MY141754A (no)
NO (1) NO20064166L (no)
NZ (2) NZ550774A (no)
PE (2) PE20060150A1 (no)
PL (1) PL1732917T3 (no)
PT (1) PT1732917E (no)
RS (1) RS51150B (no)
SI (1) SI1732917T1 (no)
TW (1) TW200602338A (no)
UA (1) UA88163C2 (no)
UY (1) UY29437A1 (no)
WO (1) WO2005092880A1 (no)
ZA (2) ZA200606056B (no)

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