NO20072283L - Fremgangsmate for fremstilling av annelerte piperazin-2-on derivater samt mellomprodukter i samme - Google Patents

Fremgangsmate for fremstilling av annelerte piperazin-2-on derivater samt mellomprodukter i samme

Info

Publication number: NO20072283L
Authority: NO; Norway
Prior art keywords: derivatives; piperazine; annealed; intermediates; preparing
Prior art date: 2004-12-02

Application number

NO20072283A

Other languages

English (en)

Norwegian (no)

Inventor

Guenter Linz

Adil Duran

Original Assignee

Boehringer Ingelheim Int

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-12-02

Filing date

2007-05-03

Publication date

2007-06-28

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35923724&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20072283(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2007-05-03 Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int

2007-06-28 Publication of NO20072283L publication Critical patent/NO20072283L/no

Links

IWELDVXSEVIIGI-UHFFFAOYSA-N piperazin-2-one Chemical class O=C1CNCCN1 IWELDVXSEVIIGI-UHFFFAOYSA-N 0.000 title abstract 2
239000000543 intermediate Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
IDAICLIJTRXNER-UHFFFAOYSA-N 5,6,7,8-tetrahydropteridine Chemical compound C1=NC=C2NCCNC2=N1 IDAICLIJTRXNER-UHFFFAOYSA-N 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/28—Oxygen atom

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Catalysts (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO20072283A 2004-12-02 2007-05-03 Fremgangsmate for fremstilling av annelerte piperazin-2-on derivater samt mellomprodukter i samme NO20072283L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE102004058337A DE102004058337A1 (de)	2004-12-02	2004-12-02	Verfahren zur Herstellung von annelierten Piperazin-2-on Derivaten
PCT/EP2005/056291 WO2006058876A1 (de)	2004-12-02	2005-11-29	Verfahren zur herstellung von annelierten piperazin-2-on derivaten sowie zwischenprodukte des verfahrens

Publications (1)

Publication Number	Publication Date
NO20072283L true NO20072283L (no)	2007-06-28

Family

ID=35923724

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20072283A NO20072283L (no)	2004-12-02	2007-05-03	Fremgangsmate for fremstilling av annelerte piperazin-2-on derivater samt mellomprodukter i samme

Country Status (34)

Country	Link
US (9)	US7238807B2 (pl)
EP (2)	EP1819706B1 (pl)
JP (1)	JP5164574B2 (pl)
KR (2)	KR101362131B1 (pl)
CN (3)	CN102093361B (pl)
AR (1)	AR053100A1 (pl)
AU (1)	AU2005311308B2 (pl)
BR (1)	BRPI0518601A2 (pl)
CA (1)	CA2588857C (pl)
CL (1)	CL2013002895A1 (pl)
CY (1)	CY1113625T1 (pl)
DE (1)	DE102004058337A1 (pl)
DK (2)	DK1819706T3 (pl)
EA (1)	EA012624B1 (pl)
ES (2)	ES2548680T3 (pl)
HR (1)	HRP20120980T1 (pl)
HU (1)	HUE027689T2 (pl)
IL (1)	IL183568A (pl)
ME (1)	ME01470B (pl)
MX (1)	MX2007006549A (pl)
MY (1)	MY147459A (pl)
NO (1)	NO20072283L (pl)
NZ (1)	NZ556182A (pl)
PE (2)	PE20061061A1 (pl)
PL (2)	PL2436685T3 (pl)
PT (1)	PT1819706E (pl)
RS (1)	RS52533B (pl)
SG (2)	SG141461A1 (pl)
SI (1)	SI1819706T1 (pl)
TW (1)	TWI362391B (pl)
UA (1)	UA89390C2 (pl)
UY (1)	UY29233A1 (pl)
WO (1)	WO2006058876A1 (pl)
ZA (1)	ZA200703368B (pl)

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DE102004033670A1 (de) *	2004-07-09	2006-02-02	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Pyridodihydropyrazinone, Verfahren zu Ihrer Herstellung und Ihre Verwendung als Arzneimittel
US7728134B2 (en) *	2004-08-14	2010-06-01	Boehringer Ingelheim International Gmbh	Hydrates and polymorphs of 4[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament
US20060035903A1 (en) *	2004-08-14	2006-02-16	Boehringer Ingelheim International Gmbh	Storage stable perfusion solution for dihydropteridinones
US20060074088A1 (en) *	2004-08-14	2006-04-06	Boehringer Ingelheim International Gmbh	Dihydropteridinones for the treatment of cancer diseases
US7759485B2 (en) *	2004-08-14	2010-07-20	Boehringer Ingelheim International Gmbh	Process for the manufacture of dihydropteridinones
US20060058311A1 (en)	2004-08-14	2006-03-16	Boehringer Ingelheim International Gmbh	Combinations for the treatment of diseases involving cell proliferation
EP1630163A1 (de) *	2004-08-25	2006-03-01	Boehringer Ingelheim Pharma GmbH & Co.KG	Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
EP1632493A1 (de) *	2004-08-25	2006-03-08	Boehringer Ingelheim Pharma GmbH & Co.KG	Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
DE102004058337A1 (de)	2004-12-02	2006-06-14	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Verfahren zur Herstellung von annelierten Piperazin-2-on Derivaten
US7439358B2 (en)	2006-02-08	2008-10-21	Boehringer Ingelheim International Gmbh	Specific salt, anhydrous and crystalline form of a dihydropteridione derivative
CA2652648C (en)	2006-02-14	2016-10-25	Vertex Pharmaceuticals Incorporated	Dihydrodiazepines useful as inhibitors of protein kinases
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ATE487720T1 (de)	2007-02-01	2010-11-15	Astrazeneca Ab	5,6,7,8-tetrahydropteridin-derivate als hsp90- hemmer
EP2185559A1 (en) *	2007-08-03	2010-05-19	Boehringer Ingelheim International GmbH	Crystalline form of a dihydropteridione derivative
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KR20120096474A (ko)	2009-09-25	2012-08-30	버텍스 파마슈티칼스 인코포레이티드	단백질 키나제 억제제로서 유용한 피리미딘 유도체의 제조 방법
KR20120094920A (ko) *	2009-09-25	2012-08-27	버텍스 파마슈티칼스 인코포레이티드	단백질 키나제 억제제로서 유용한 피리미딘 유도체의 제조 방법
US8546566B2 (en)	2010-10-12	2013-10-01	Boehringer Ingelheim International Gmbh	Process for manufacturing dihydropteridinones and intermediates thereof
US9358233B2 (en)	2010-11-29	2016-06-07	Boehringer Ingelheim International Gmbh	Method for treating acute myeloid leukemia
WO2012148548A1 (en)	2011-02-25	2012-11-01	Takeda Pharmaceutical Company Limited	N-substituted oxazinopteridines and oxazinopteridinones
US9370535B2 (en)	2011-05-17	2016-06-21	Boehringer Ingelheim International Gmbh	Method for treatment of advanced solid tumors
TW201414734A (zh)	2012-07-10	2014-04-16	Takeda Pharmaceutical	氮雜吲哚衍生物
WO2015011236A1 (en)	2013-07-26	2015-01-29	Boehringer Ingelheim International Gmbh	Treatment of myelodysplastic syndrome
AR099052A1 (es)	2014-01-09	2016-06-29	Takeda Pharmaceuticals Co	Derivados de azaindol
US9867831B2 (en)	2014-10-01	2018-01-16	Boehringer Ingelheim International Gmbh	Combination treatment of acute myeloid leukemia and myelodysplastic syndrome

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DE102004033670A1 (de)	2004-07-09	2006-02-02	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Pyridodihydropyrazinone, Verfahren zu Ihrer Herstellung und Ihre Verwendung als Arzneimittel
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JP2009503014A (ja)	2005-08-03	2009-01-29	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	呼吸器系疾患の治療におけるジヒドロプテリジノン
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2004
- 2004-12-02 DE DE102004058337A patent/DE102004058337A1/de not_active Withdrawn
2005
- 2005-11-22 US US11/284,836 patent/US7238807B2/en not_active Ceased
- 2005-11-29 AU AU2005311308A patent/AU2005311308B2/en not_active Ceased
- 2005-11-29 SG SG200802431-7A patent/SG141461A1/en unknown
- 2005-11-29 PL PL11189691T patent/PL2436685T3/pl unknown
- 2005-11-29 HU HUE11189691A patent/HUE027689T2/hu unknown
- 2005-11-29 DK DK05823799.1T patent/DK1819706T3/da active
- 2005-11-29 EP EP05823799A patent/EP1819706B1/de not_active Expired - Lifetime
- 2005-11-29 ME MEP-2012-124A patent/ME01470B/me unknown
- 2005-11-29 PT PT58237991T patent/PT1819706E/pt unknown
- 2005-11-29 RS RS20120519A patent/RS52533B/sr unknown
- 2005-11-29 CA CA2588857A patent/CA2588857C/en not_active Expired - Fee Related
- 2005-11-29 WO PCT/EP2005/056291 patent/WO2006058876A1/de not_active Ceased
- 2005-11-29 UA UAA200706986A patent/UA89390C2/ru unknown
- 2005-11-29 BR BRPI0518601-3A patent/BRPI0518601A2/pt not_active IP Right Cessation
- 2005-11-29 JP JP2007543838A patent/JP5164574B2/ja not_active Expired - Lifetime
- 2005-11-29 NZ NZ556182A patent/NZ556182A/en not_active IP Right Cessation
- 2005-11-29 SG SG201000003-2A patent/SG158848A1/en unknown
- 2005-11-29 UY UY29233A patent/UY29233A1/es not_active Application Discontinuation
- 2005-11-29 ES ES11189691.6T patent/ES2548680T3/es not_active Expired - Lifetime
- 2005-11-29 KR KR1020077015136A patent/KR101362131B1/ko not_active Expired - Fee Related
- 2005-11-29 CN CN201010593286.0A patent/CN102093361B/zh not_active Expired - Fee Related
- 2005-11-29 CN CN2010105934512A patent/CN102070637B/zh not_active Expired - Fee Related
- 2005-11-29 ES ES05823799T patent/ES2395829T3/es not_active Expired - Lifetime
- 2005-11-29 KR KR1020127028659A patent/KR101395591B1/ko not_active Expired - Fee Related
- 2005-11-29 MX MX2007006549A patent/MX2007006549A/es active IP Right Grant
- 2005-11-29 EA EA200701164A patent/EA012624B1/ru not_active IP Right Cessation
- 2005-11-29 EP EP11189691.6A patent/EP2436685B1/de not_active Expired - Lifetime
- 2005-11-29 CN CN2005800406546A patent/CN101065381B/zh not_active Expired - Fee Related
- 2005-11-29 SI SI200531631T patent/SI1819706T1/sl unknown
- 2005-11-29 HR HRP20120980TT patent/HRP20120980T1/hr unknown
- 2005-11-29 DK DK11189691.6T patent/DK2436685T3/en active
- 2005-11-29 PL PL05823799T patent/PL1819706T3/pl unknown
- 2005-11-30 PE PE2005001388A patent/PE20061061A1/es not_active Application Discontinuation
- 2005-11-30 PE PE2009000418A patent/PE20090488A1/es not_active Application Discontinuation
- 2005-11-30 MY MYPI20055607A patent/MY147459A/en unknown
- 2005-12-01 TW TW094142312A patent/TWI362391B/zh not_active IP Right Cessation
- 2005-12-02 AR ARP050105040A patent/AR053100A1/es unknown
2007
- 2007-04-25 ZA ZA200703368A patent/ZA200703368B/xx unknown
- 2007-05-03 NO NO20072283A patent/NO20072283L/no not_active Application Discontinuation
- 2007-05-16 US US11/749,208 patent/US20070219369A1/en not_active Abandoned
- 2007-05-16 US US11/749,205 patent/US20070213529A1/en not_active Abandoned
- 2007-05-16 US US11/749,210 patent/US20070213531A1/en not_active Abandoned
- 2007-05-16 US US11/749,203 patent/US20070213528A1/en not_active Abandoned
- 2007-05-16 US US11/749,206 patent/US7626019B2/en active Active
- 2007-05-16 US US11/749,212 patent/US20070213530A1/en not_active Abandoned
- 2007-05-16 US US11/749,207 patent/US20070213534A1/en not_active Abandoned
- 2007-05-31 IL IL183568A patent/IL183568A/en not_active IP Right Cessation
2010
- 2010-08-05 US US12/850,993 patent/USRE43115E1/en not_active Expired - Lifetime
2012
- 2012-12-12 CY CY20121101215T patent/CY1113625T1/el unknown
2013
- 2013-10-09 CL CL2013002895A patent/CL2013002895A1/es unknown

Also Published As

Publication number	Publication date
ES2395829T3 (es)	2013-02-15
UA89390C2 (ru)	2010-01-25
DK1819706T3 (da)	2013-01-02
SI1819706T1 (sl)	2013-01-31
US20070213534A1 (en)	2007-09-13
HUE027689T2 (hu)	2021-12-28
AR053100A1 (es)	2007-04-25
HK1158199A1 (en)	2012-07-13
US20070213530A1 (en)	2007-09-13
CY1113625T1 (el)	2016-06-22
PT1819706E (pt)	2012-12-06
IL183568A (en)	2015-02-26
ZA200703368B (en)	2008-09-25
CN101065381B (zh)	2011-03-30
CN102070637A (zh)	2011-05-25
CN102093361B (zh)	2014-05-07
CN101065381A (zh)	2007-10-31
PE20061061A1 (es)	2006-11-10
WO2006058876A1 (de)	2006-06-08
EA200701164A1 (ru)	2007-12-28
US20070208027A1 (en)	2007-09-06
AU2005311308A1 (en)	2006-06-08
TWI362391B (en)	2012-04-21
ES2548680T3 (es)	2015-10-20
EA012624B1 (ru)	2009-10-30
KR20070092252A (ko)	2007-09-12
US20070213528A1 (en)	2007-09-13
US7238807B2 (en)	2007-07-03
KR101362131B1 (ko)	2014-02-19
HK1158200A1 (en)	2012-07-13
PL1819706T3 (pl)	2013-03-29
KR20120136414A (ko)	2012-12-18
US7626019B2 (en)	2009-12-01
EP2436685A1 (de)	2012-04-04
CL2013002895A1 (es)	2014-03-14
US20070219369A1 (en)	2007-09-20
CA2588857C (en)	2013-10-08
RS52533B (sr)	2013-04-30
CA2588857A1 (en)	2006-06-08
HK1113489A1 (en)	2008-10-03
EP2436685B1 (de)	2015-07-01
KR101395591B1 (ko)	2014-05-16
BRPI0518601A2 (pt)	2008-11-25
ME01470B (me)	2014-04-20
NZ556182A (en)	2009-08-28
MX2007006549A (es)	2007-06-18
CN102093361A (zh)	2011-06-15
PL2436685T3 (pl)	2015-11-30
AU2005311308B2 (en)	2012-04-12
IL183568A0 (en)	2007-09-20
JP2008521861A (ja)	2008-06-26
MY147459A (en)	2012-12-14
SG141461A1 (en)	2008-04-28
SG158848A1 (en)	2010-02-26
HRP20120980T1 (hr)	2012-12-31
EP1819706B1 (de)	2012-09-19
DE102004058337A1 (de)	2006-06-14
CN102070637B (zh)	2012-09-26
USRE43115E1 (en)	2012-01-17
JP5164574B2 (ja)	2013-03-21
DK2436685T3 (en)	2015-09-14
US20060122393A1 (en)	2006-06-08
PE20090488A1 (es)	2009-05-27
EP1819706A1 (de)	2007-08-22
US20070213531A1 (en)	2007-09-13
TW200628471A (en)	2006-08-16
US20070213529A1 (en)	2007-09-13
UY29233A1 (es)	2006-07-31

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Date	Code	Title	Description
2016-06-27	FC2A	Withdrawal, rejection or dismissal of laid open patent application

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