NO20072547L - 4-metoksymetyl-pyrrolidin-2-karboksylsyreforbindelser og derivater derav som hepatitt C virusinhibitorer - Google Patents

4-metoksymetyl-pyrrolidin-2-karboksylsyreforbindelser og derivater derav som hepatitt C virusinhibitorer

Info

Publication number: NO20072547L
Authority: NO; Norway
Prior art keywords: methoxymethyl; thiazol; pyrrolidine; hepatitis; derivatives
Prior art date: 2004-10-25

Application number

NO20072547A

Other languages

English (en)

Norwegian (no)

Inventor

Charles David Hartley

Stephen Allan Smith

Fabrizio Nerozzi

Rossella Guidetti

David Haigh

Peter David Howes

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-10-25

Filing date

2007-05-18

Publication date

2007-07-23

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33485164&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20072547(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2007-05-18 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2007-07-23 Publication of NO20072547L publication Critical patent/NO20072547L/no

Links

NEGCDNJQEDCABL-UHFFFAOYSA-N 4-(methoxymethyl)pyrrolidine-2-carboxylic acid Chemical class COCC1CNC(C(O)=O)C1 NEGCDNJQEDCABL-UHFFFAOYSA-N 0.000 title 1
241000711549 Hepacivirus C Species 0.000 title 1
239000003112 inhibitor Substances 0.000 title 1
-1 4-tert-butyl-3-methoxyphenyl Chemical group 0.000 abstract 7
125000000217 alkyl group Chemical group 0.000 abstract 1
239000003443 antiviral agent Substances 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000005160 aryl oxy alkyl group Chemical group 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
125000004184 methoxymethyl group Chemical group [H]C([H])([H])OC([H])([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000012453 solvate Substances 0.000 abstract 1
125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Virology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Gastroenterology & Hepatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO20072547A 2004-10-25 2007-05-18 4-metoksymetyl-pyrrolidin-2-karboksylsyreforbindelser og derivater derav som hepatitt C virusinhibitorer NO20072547L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0423673.3A GB0423673D0 (en)	2004-10-25	2004-10-25	Compounds
PCT/EP2005/011532 WO2006045613A1 (fr)	2004-10-25	2005-10-24	Composes d'acide 4-methoxymethyl-pyrrolidine-2-carboxylique et leurs derives utilises comme inhibiteurs du virus de l'hepatite c

Publications (1)

Publication Number	Publication Date
NO20072547L true NO20072547L (no)	2007-07-23

Family

ID=33485164

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20072547A NO20072547L (no)	2004-10-25	2007-05-18	4-metoksymetyl-pyrrolidin-2-karboksylsyreforbindelser og derivater derav som hepatitt C virusinhibitorer

Country Status (18)

Country	Link
US (1)	US20070270475A1 (fr)
EP (1)	EP1805172A1 (fr)
JP (1)	JP2008517968A (fr)
KR (1)	KR20070072614A (fr)
CN (1)	CN101087785A (fr)
AR (1)	AR051340A1 (fr)
AU (1)	AU2005298849A1 (fr)
BR (1)	BRPI0517023A (fr)
CA (1)	CA2585170A1 (fr)
GB (1)	GB0423673D0 (fr)
IL (1)	IL182583A0 (fr)
MA (1)	MA29000B1 (fr)
MX (1)	MX2007004914A (fr)
NO (1)	NO20072547L (fr)
PE (1)	PE20060602A1 (fr)
RU (1)	RU2007119390A (fr)
TW (1)	TW200630365A (fr)
WO (1)	WO2006045613A1 (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE554085T1 (de)	2006-11-30	2012-05-15	Probiodrug Ag	Neue inhibitoren von glutaminylcyclase
EP2142215B1 (fr)	2007-05-04	2012-03-07	Vertex Pharmceuticals Incorporated	Thérapie combinée pour le traitement d'une infection par le vhc
UA103195C2 (uk)	2008-08-11	2013-09-25	Глаксосмитклайн Ллк	Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань
BRPI0917458A2 (pt)	2008-08-11	2015-12-01	Glaxosmithkline Llc	composto, método de tratamento de doenças e condições, composição farmacêutica, método para tratar ou prevenir doença, e, uso de um composto
BRPI0917013A2 (pt)	2008-08-11	2016-02-16	Glaxosmithkline Llc	métodos para tratar doenças alérgicas e outras condições inflamatórias, e para tratar ou prevenir doença, composto, composição farmacêutica, e, uso de um composto
WO2011098451A1 (fr)	2010-02-10	2011-08-18	Glaxosmithkline Llc	Dérivés de purine et leurs utilisations pharmaceutiques
DK2534149T3 (da)	2010-02-10	2015-01-05	Glaxosmithkline Llc	6-amino-2-{ [ (1s)-1-methylbutyl]oxy}-9-[5-(1-piperidinyl)pentyl]-7,9-dihydro-8h-purin-8-on-maleat
KR20160124157A (ko)	2014-02-20	2016-10-26	글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드	인간 인터페론의 유도인자로서의 피롤로[3,2]피리미딘 유도체
IL247927B (en)	2014-05-07	2022-09-01	Boehringer Ingelheim Int	Container, a device that turns a liquid into a fine spray and use
MX2017006302A (es)	2014-11-13	2018-02-16	Glaxosmithkline Biologicals Sa	Derivados de adenina que son utiles en el tratamiento de enfermedades alergicas u otras afecciones inflamatorias.
CN107849084B (zh)	2015-12-03	2021-09-14	葛兰素史密斯克莱知识产权发展有限公司	作为sting调节剂的环状嘌呤二核苷酸
JP2019510802A (ja)	2016-04-07	2019-04-18	グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅＩｎｔｅｌｌｅｃｔｕａｌＰｒｏｐｅｒｔｙＤｅｖｅｌｏｐｍｅｎｔＬｉｍｉｔｅｄ	タンパク質調節物質として有用な複素環アミド
PT3440076T (pt)	2016-04-07	2022-07-29	Glaxosmithkline Ip Dev Ltd	Amidas heterocíclicas úteis como modeladores de proteína
CA3077337A1 (fr)	2017-10-05	2019-04-11	Glaxosmithkline Intellectual Property Development Limited	Modulateurs de stimulateur des genes (sting) de l'interferon
AU2018344902B2 (en)	2017-10-05	2021-06-03	Glaxosmithkline Intellectual Property Development Limited	Modulators of stimulator of interferon genes (STING) useful in treating HIV
GB201807924D0 (en)	2018-05-16	2018-06-27	Ctxt Pty Ltd	Compounds
US20220227761A1 (en)	2019-05-16	2022-07-21	Stingthera, Inc.	Oxoacridinyl acetic acid derivatives and methods of use
WO2020232378A1 (fr)	2019-05-16	2020-11-19	Silicon Swat, Inc.	Dérivés d'acide acétique benzo[b][1,8]naphtyridine et leur procédés d'utilisation
GB201910304D0 (en)	2019-07-18	2019-09-04	Ctxt Pty Ltd	Compounds
GB201910305D0 (en)	2019-07-18	2019-09-04	Ctxt Pty Ltd	Compounds
EP4077318B1 (fr)	2019-12-18	2025-10-15	Ctxt Pty Ltd	Dimères de benzimidazole en tant que modulateurs de sting
US12274700B1 (en)	2020-10-30	2025-04-15	Accencio LLC	Methods of treating symptoms of coronavirus infection with RNA polymerase inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE60325498D1 (de) *	2002-10-24	2009-02-05	Glaxo Group Ltd	1-acyl-pyrrolidin-derivate für die behandlung von viralen infektionen

2004
- 2004-10-25 GB GBGB0423673.3A patent/GB0423673D0/en not_active Ceased
2005
- 2005-10-21 PE PE2005001239A patent/PE20060602A1/es not_active Application Discontinuation
- 2005-10-24 RU RU2007119390/04A patent/RU2007119390A/ru unknown
- 2005-10-24 WO PCT/EP2005/011532 patent/WO2006045613A1/fr not_active Ceased
- 2005-10-24 KR KR1020077011741A patent/KR20070072614A/ko not_active Withdrawn
- 2005-10-24 US US11/568,127 patent/US20070270475A1/en not_active Abandoned
- 2005-10-24 JP JP2007538336A patent/JP2008517968A/ja active Pending
- 2005-10-24 AU AU2005298849A patent/AU2005298849A1/en not_active Abandoned
- 2005-10-24 CN CNA2005800447014A patent/CN101087785A/zh active Pending
- 2005-10-24 AR ARP050104434A patent/AR051340A1/es not_active Application Discontinuation
- 2005-10-24 BR BRPI0517023-0A patent/BRPI0517023A/pt not_active Application Discontinuation
- 2005-10-24 EP EP05799541A patent/EP1805172A1/fr not_active Withdrawn
- 2005-10-24 MX MX2007004914A patent/MX2007004914A/es unknown
- 2005-10-24 TW TW094137066A patent/TW200630365A/zh unknown
- 2005-10-24 CA CA002585170A patent/CA2585170A1/fr not_active Abandoned
2007
- 2007-04-16 IL IL182583A patent/IL182583A0/en unknown
- 2007-04-25 MA MA29846A patent/MA29000B1/fr unknown
- 2007-05-18 NO NO20072547A patent/NO20072547L/no unknown

Also Published As

Publication number	Publication date
RU2007119390A (ru)	2008-12-10
BRPI0517023A (pt)	2008-09-30
AR051340A1 (es)	2007-01-03
CA2585170A1 (fr)	2006-05-04
JP2008517968A (ja)	2008-05-29
GB0423673D0 (en)	2004-11-24
WO2006045613A1 (fr)	2006-05-04
EP1805172A1 (fr)	2007-07-11
US20070270475A1 (en)	2007-11-22
IL182583A0 (en)	2007-07-24
PE20060602A1 (es)	2006-07-15
AU2005298849A1 (en)	2006-05-04
TW200630365A (en)	2006-09-01
CN101087785A (zh)	2007-12-12
MX2007004914A (es)	2007-06-12
MA29000B1 (fr)	2007-11-01
KR20070072614A (ko)	2007-07-04

Publication	Publication Date	Title
NO20072547L (no)	2007-07-23	4-metoksymetyl-pyrrolidin-2-karboksylsyreforbindelser og derivater derav som hepatitt C virusinhibitorer
NO20052472L (no)	2005-05-23	1-acyl-pyrrolidinderivater for behandling av virale infeksjoner.
EA200800476A1 (ru)	2008-08-29	Макроциклические ингибиторы вируса гепатита с
BRPI0510623A (pt)	2007-10-30	compostos de derivados de prolina e morfolina
CY1112254T1 (el)	2015-12-09	Αρυλικοι φωσφοραμιδικοι εστερες νουκλεοζιτων και οι χρησεις τους ως αντι-ιικοι παραγοντες για την αντιμετωπιση του ιου της ηπατιτιδας c
NO20085269L (no)	2009-03-05	2-tioksantinderivater som fungerer som MPO-inhibitorer
NO20085169L (no)	2009-01-20	Krystallinske solvater og komplekser av (1S)-1,5-anhydro-L-C- (3-((fenyl)metyl)fenyl)-D-glucitol derivater med aminosyrer som SGLT2-inhibitorer for behandling av diabetes
WO2008108386A1 (fr)	2008-09-12	Composition pharmaceutique
PE20071326A1 (es)	2008-02-21	Inhibidores de la polimerasa viral
CY1115533T1 (el)	2017-01-04	Παραγωγα χολικου οξεος ως προσδετες fxr για την προληψη ή τη θεραπευτικη αγωγη νοσηματων ή καταστασεων οι οποιες προκαλουνται με τη μεσολαβηση fxr
NO20082934L (no)	2008-09-02	Antivirale nukleotider
NO20074763L (no)	2007-11-16	(1,5-difenyl-1H-pyrazol-3-yl)oksadiazolderivater, fremgangsmate ved fremstilling derav og anvendelse av samme i terapi
NO20071274L (no)	2007-05-14	Inhibitorer av hepatitt C virus RNA-avhengig RNA polymerase, og sammensetninger og behandlinger ved anvendelse av samme.
EA201101492A1 (ru)	2012-09-28	Аналоги тиофена для лечения или предупреждения флавивирусных инфекций
NO20072689L (no)	2007-07-17	Tetrasykliske indolderivater som antivirale midler
NO20083917L (no)	2008-10-23	Malonamidderivater som gammasekretaseinhibitorer
TW200616994A (en)	2006-06-01	Novel thiophene derivatives
BRPI0810524B8 (pt)	2021-05-25	derivado de (aza)indol, inibidor de xantina oxidase e composição farmacêutica compreendendo o dito derivado
ECSP055815A (es)	2005-08-11	Composición para el tratamiento de la infección por virus flaviviridae
DE602007008616D1 (de)	2010-09-30	Verfahren zur herstellung von 4'-azidocytidinderivaten
MX2009012613A (es)	2010-04-21	Tiazoles substituidos por heteroarilo y su uso como agentes antivirales.
UA109638C2 (uk)	2015-09-25	Сполуки та спосіб зниження рівня сечової кислоти
JP2012500258A5 (fr)	2012-10-04
NO20082148L (no)	2008-06-24	Kjemiske forbindelser
DE502005009091D1 (de)	2010-04-08	NEUE 2-SUBSTITUIERTE D-HOMO ESTRA-1,3,5(10)-TRIENE ALS INHIBITOREN DER 17ß-HYDROXYSTEROIDDEHYDROGENASE TYP 1