NO20072931L - Forbedret doseringsregime av temozolomid for behandling av kreft basert pa pasientens MGMT-niva - Google Patents
Forbedret doseringsregime av temozolomid for behandling av kreft basert pa pasientens MGMT-nivaInfo
- Publication number
- NO20072931L NO20072931L NO20072931A NO20072931A NO20072931L NO 20072931 L NO20072931 L NO 20072931L NO 20072931 A NO20072931 A NO 20072931A NO 20072931 A NO20072931 A NO 20072931A NO 20072931 L NO20072931 L NO 20072931L
- Authority
- NO
- Norway
- Prior art keywords
- treatment
- temozolomide
- patient
- dosing regimen
- cancer based
- Prior art date
Links
- BPEGJWRSRHCHSN-UHFFFAOYSA-N Temozolomide Chemical compound O=C1N(C)N=NC2=C(C(N)=O)N=CN21 BPEGJWRSRHCHSN-UHFFFAOYSA-N 0.000 title abstract 4
- 229960004964 temozolomide Drugs 0.000 title abstract 4
- 102100025825 Methylated-DNA-protein-cysteine methyltransferase Human genes 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 201000011510 cancer Diseases 0.000 title abstract 2
- 108040008770 methylated-DNA-[protein]-cysteine S-methyltransferase activity proteins Proteins 0.000 title abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/91005—Transferases (2.) transferring one-carbon groups (2.1)
- G01N2333/91011—Methyltransferases (general) (2.1.1.)
- G01N2333/91017—Methyltransferases (general) (2.1.1.) with definite EC number (2.1.1.-)
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62625804P | 2004-11-09 | 2004-11-09 | |
| PCT/US2005/040449 WO2006052976A2 (fr) | 2004-11-09 | 2005-11-07 | Methodes de traitement |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20072931L true NO20072931L (no) | 2007-08-03 |
Family
ID=36168622
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20072931A NO20072931L (no) | 2004-11-09 | 2007-06-08 | Forbedret doseringsregime av temozolomid for behandling av kreft basert pa pasientens MGMT-niva |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20060100188A1 (fr) |
| EP (1) | EP1830845A2 (fr) |
| JP (2) | JP2008519584A (fr) |
| CN (1) | CN101098696A (fr) |
| AU (1) | AU2005304672B2 (fr) |
| BR (1) | BRPI0517976A (fr) |
| CA (1) | CA2585446A1 (fr) |
| MX (1) | MX2007005581A (fr) |
| NO (1) | NO20072931L (fr) |
| NZ (1) | NZ554831A (fr) |
| TW (1) | TW200630089A (fr) |
| WO (1) | WO2006052976A2 (fr) |
| ZA (1) | ZA200703716B (fr) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101172104B (zh) * | 2002-02-22 | 2013-04-03 | 默沙东公司 | 抗肿瘤剂,特别是替莫唑胺的药物制剂,其制备方法和用途 |
| EP1830845A2 (fr) * | 2004-11-09 | 2007-09-12 | Shering Corporation | Regime de dosage ameliore de temozolomide pour le traitement du cancer fonde sur le niveau de mgmt du patient |
| US20070111979A1 (en) * | 2005-11-07 | 2007-05-17 | Walter Robert Bishop | Methods of treating cell proliferative disorders using a compressed temozolomide dosing schedule |
| EP1976515A2 (fr) * | 2006-01-17 | 2008-10-08 | Abbott Laboratories | Polythérapie faisant appel à des inhibiteurs de la parp |
| CN103751186B (zh) | 2006-04-05 | 2016-08-24 | 欧科生医股份有限公司 | 药物制剂:8-[{1-(3,5-双-(三氟甲基)苯基)-乙氧基}-甲基]-8-苯基-1,7-二氮杂-螺[4.5]癸-2-酮的盐及用其治疗的方法 |
| HUE028908T2 (en) | 2006-04-05 | 2017-01-30 | Opko Health Inc | The hydrochloride salt of 8 - [{1- (3,5-bis (trifluoromethyl) phenyl) ethoxy} methyl] -8-phenyl-1,7-diazaspiro [4.5] decan-2-one, and process |
| US20070264672A1 (en) * | 2006-05-09 | 2007-11-15 | Bimalendu Dasmahapatra | Development of a novel assay for mgmt (methyl guanine methyl transferase) |
| AR061618A1 (es) * | 2006-06-26 | 2008-09-10 | Schering Corp | Formas de dosificacion unitaria de temozolomida |
| CA2686848A1 (fr) * | 2007-05-08 | 2008-11-20 | Schering Corporation | Procedes de traitement par formulations intraveineuses comprenant du temozolomide |
| US20080319039A1 (en) * | 2007-06-25 | 2008-12-25 | Jacqueline Rose Bersch | Unit dosage forms of temozolomide |
| US8435972B2 (en) * | 2010-09-02 | 2013-05-07 | Emory University | Method for the treatment of central nervous system cancers and compositions related thereto |
| US9630966B2 (en) * | 2013-04-17 | 2017-04-25 | Signal Pharmaceuticals, Llc | Treatment of cancer with dihydropyrazino-pyrazines |
| CA2982205A1 (fr) | 2015-04-10 | 2016-10-13 | David W. Andrews | Procedes et compositions de traitement de cancers et d'amelioration de l'immunite therapeutique par reduction selective des monocytes m2 immunomodulateurs |
| CN110408694A (zh) * | 2018-04-26 | 2019-11-05 | 胤安国际(辽宁)基因科技股份有限公司 | 评估替莫唑胺在治疗脑胶质瘤患者的敏感性的新方法 |
| WO2020198587A1 (fr) * | 2019-03-28 | 2020-10-01 | Thomas Jefferson University | Méthodes de traitement de cancers à l'aide d'acides nucléiques antisens |
| WO2023113538A1 (fr) * | 2021-12-17 | 2023-06-22 | 숙명여자대학교산학협력단 | Polythérapie à base de griséofulvine pour le traitement d'une tumeur cérébrale |
| CN119318654A (zh) * | 2024-12-16 | 2025-01-17 | 中国医学科学院基础医学研究所 | 氟达拉滨和替莫唑胺联用在治疗脑胶质瘤中的应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5260291A (en) * | 1981-08-24 | 1993-11-09 | Cancer Research Campaign Technology Limited | Tetrazine derivatives |
| US5876146A (en) * | 1995-10-27 | 1999-03-02 | General Electric Company | Apparatus and methods for repairing jet pump diffusers in a nuclear reactor |
| US5786146A (en) * | 1996-06-03 | 1998-07-28 | The Johns Hopkins University School Of Medicine | Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids |
| US6017704A (en) * | 1996-06-03 | 2000-01-25 | The Johns Hopkins University School Of Medicine | Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids |
| US5939098A (en) * | 1996-09-19 | 1999-08-17 | Schering Corporation | Cancer treatment with temozolomide |
| CN1345240A (zh) * | 1999-03-30 | 2002-04-17 | 先灵公司 | 用替莫唑胺改善癌症治疗 |
| US6346524B1 (en) * | 1999-03-30 | 2002-02-12 | Schering Corporation | Cancer treatment with temozolomide |
| WO2001085221A2 (fr) * | 2000-05-12 | 2001-11-15 | Duke University | Reactifs et methodes de dosage des niveaux de $i(0)6-alkylguanine-adn alkyltransferase $i(in vivo) (agt) |
| US6773897B2 (en) * | 2000-09-29 | 2004-08-10 | The Johns Hopkins University School Of Medicine | Method of predicting the clinical response to chemotherapeutic treatment with alkylating agents |
| EP1332208A2 (fr) * | 2000-10-30 | 2003-08-06 | Gene Logic, Inc. | Acides nucleiques partiellement bicatenaires, leurs procedes de production et leur utilisation |
| ATE502030T1 (de) * | 2000-11-20 | 2011-04-15 | Takeda Pharmaceutical | Imidazolderivate, verfahren zu deren herstellung und deren verwendung |
| WO2004038404A2 (fr) * | 2002-10-28 | 2004-05-06 | Pharmacia Italia Spa | Procede permettant d'optimiser l'efficacite therapeutique de la nemorubicine |
| US7718364B2 (en) * | 2003-03-25 | 2010-05-18 | John Wayne Cancer Institute | DNA markers for management of cancer |
| EP1830845A2 (fr) * | 2004-11-09 | 2007-09-12 | Shering Corporation | Regime de dosage ameliore de temozolomide pour le traitement du cancer fonde sur le niveau de mgmt du patient |
| US20070111979A1 (en) * | 2005-11-07 | 2007-05-17 | Walter Robert Bishop | Methods of treating cell proliferative disorders using a compressed temozolomide dosing schedule |
-
2005
- 2005-11-07 EP EP05851437A patent/EP1830845A2/fr not_active Withdrawn
- 2005-11-07 MX MX2007005581A patent/MX2007005581A/es unknown
- 2005-11-07 JP JP2007540176A patent/JP2008519584A/ja active Pending
- 2005-11-07 CN CNA2005800461914A patent/CN101098696A/zh active Pending
- 2005-11-07 CA CA002585446A patent/CA2585446A1/fr not_active Abandoned
- 2005-11-07 BR BRPI0517976-9A patent/BRPI0517976A/pt not_active IP Right Cessation
- 2005-11-07 WO PCT/US2005/040449 patent/WO2006052976A2/fr not_active Ceased
- 2005-11-07 NZ NZ554831A patent/NZ554831A/en not_active IP Right Cessation
- 2005-11-07 US US11/268,160 patent/US20060100188A1/en not_active Abandoned
- 2005-11-07 AU AU2005304672A patent/AU2005304672B2/en not_active Ceased
- 2005-11-08 TW TW094139158A patent/TW200630089A/zh unknown
-
2007
- 2007-05-08 ZA ZA200703716A patent/ZA200703716B/xx unknown
- 2007-06-08 NO NO20072931A patent/NO20072931L/no not_active Application Discontinuation
-
2009
- 2009-02-25 US US12/392,591 patent/US20090247598A1/en not_active Abandoned
-
2011
- 2011-01-11 JP JP2011003480A patent/JP2011121960A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005304672B2 (en) | 2010-03-11 |
| US20090247598A1 (en) | 2009-10-01 |
| TW200630089A (en) | 2006-09-01 |
| EP1830845A2 (fr) | 2007-09-12 |
| BRPI0517976A (pt) | 2008-10-21 |
| CA2585446A1 (fr) | 2006-05-18 |
| US20060100188A1 (en) | 2006-05-11 |
| WO2006052976A3 (fr) | 2006-08-17 |
| MX2007005581A (es) | 2007-05-23 |
| CN101098696A (zh) | 2008-01-02 |
| JP2011121960A (ja) | 2011-06-23 |
| NZ554831A (en) | 2009-10-30 |
| ZA200703716B (en) | 2008-09-25 |
| WO2006052976A2 (fr) | 2006-05-18 |
| JP2008519584A (ja) | 2008-06-12 |
| AU2005304672A1 (en) | 2006-05-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |