NO20073628L - Pyridoner som er nyttige som inhibitorer av kinaser - Google Patents

Pyridoner som er nyttige som inhibitorer av kinaser

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Publication number
NO20073628L
NO20073628L NO20073628A NO20073628A NO20073628L NO 20073628 L NO20073628 L NO 20073628L NO 20073628 A NO20073628 A NO 20073628A NO 20073628 A NO20073628 A NO 20073628A NO 20073628 L NO20073628 L NO 20073628L
Authority
NO
Norway
Prior art keywords
inhibitors
kinases
compounds
useful
pyridones useful
Prior art date
Application number
NO20073628A
Other languages
English (en)
Inventor
Juan-Miguel Jimenez
Jean-Damien Charrier
Steven Durrant
Sham Ramaya
Alistair Rutherford
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of NO20073628L publication Critical patent/NO20073628L/no

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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Abstract

S a m m e n d r a g Foreliggende oppfinnelse vedrører forbindelser som er nyttige som inhibitorer av proteinkinaser. Oppfinnelsen tilveiebringer også farmasøytisk akseptable sammensetninger omfattende nevnte forbindelser og metoder for å anvende sammensetningene i behandlingen av forskjellige sykdommer, tilstander eller forstyrrelser. Oppfinnelsen tilveiebringer også fremgangsmåter for fremstilling av forbindelsene ifølge oppfinnelsen og intermediære forbindelser som er nyttige i disse prosesser. ?? ?? ?? ??
NO20073628A 2004-12-16 2007-07-16 Pyridoner som er nyttige som inhibitorer av kinaser NO20073628L (no)

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PCT/US2005/045336 WO2006065946A1 (en) 2004-12-16 2005-12-15 Pyrid-2-ones useful as inhibitors of tec family protein kinases for the treatment of inflammatory, proliferative and immunologically-mediated diseases

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CA2591413A1 (en) 2006-06-22
US20130184259A1 (en) 2013-07-18
WO2006065946A1 (en) 2006-06-22
KR20070095952A (ko) 2007-10-01
JP2009062391A (ja) 2009-03-26
US20120190699A1 (en) 2012-07-26
MX2007007330A (es) 2007-10-04
TW200633980A (en) 2006-10-01
RU2423351C2 (ru) 2011-07-10
AU2005316540A1 (en) 2006-06-22
RU2007126832A (ru) 2009-03-27
US20060183911A1 (en) 2006-08-17
IL183922A0 (en) 2007-10-31
JP2008524233A (ja) 2008-07-10
EP1831168B1 (en) 2014-07-02
JP2013213046A (ja) 2013-10-17
US8338597B2 (en) 2012-12-25
EP1831168A1 (en) 2007-09-12

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