NO20073878L - Kinazolinderivater som tyrosin kinase inhibitorer - Google Patents

Kinazolinderivater som tyrosin kinase inhibitorer

Info

Publication number: NO20073878L
Authority: NO; Norway
Prior art keywords: quinazoline derivatives; tyrosine kinase; kinase inhibitors; formula; medicament
Prior art date: 2005-02-26

Application number

NO20073878A

Other languages

English (en)

Norwegian (no)

Inventor

Richard Anthony Storey

Alleyn Plowright

Christopher Thomas Halsall

Laurent Francois And Hennequin

Kieran Lennon

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-02-26

Filing date

2007-07-24

Publication date

2007-10-23

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36390222&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20073878(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2005-02-26 Priority claimed from GB0504018A external-priority patent/GB0504018D0/en

2005-03-31 Priority claimed from GB0506657A external-priority patent/GB0506657D0/en

2005-11-25 Priority claimed from GB0524001A external-priority patent/GB0524001D0/en

2007-07-24 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2007-10-23 Publication of NO20073878L publication Critical patent/NO20073878L/no

Links

125000002294 quinazolinyl group Chemical class N1=C(N=CC2=CC=CC=C12)* 0.000 title abstract 3
229940121358 tyrosine kinase inhibitor Drugs 0.000 title 1
239000005483 tyrosine kinase inhibitor Substances 0.000 title 1
102000001301 EGF receptor Human genes 0.000 abstract 1
108060006698 EGF receptor Proteins 0.000 abstract 1
206010028980 Neoplasm Diseases 0.000 abstract 1
102000004022 Protein-Tyrosine Kinases Human genes 0.000 abstract 1
108090000412 Protein-Tyrosine Kinases Proteins 0.000 abstract 1
230000001028 anti-proliverative effect Effects 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
102000052116 epidermal growth factor receptor activity proteins Human genes 0.000 abstract 1
108700015053 epidermal growth factor receptor activity proteins Proteins 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
230000001404 mediated effect Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
YOHYSYJDKVYCJI-UHFFFAOYSA-N n-[3-[[6-[3-(trifluoromethyl)anilino]pyrimidin-4-yl]amino]phenyl]cyclopropanecarboxamide Chemical compound FC(F)(F)C1=CC=CC(NC=2N=CN=C(NC=3C=C(NC(=O)C4CC4)C=CC=3)C=2)=C1 YOHYSYJDKVYCJI-UHFFFAOYSA-N 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO20073878A 2005-02-26 2007-07-24 Kinazolinderivater som tyrosin kinase inhibitorer NO20073878L (no)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB0504018A GB0504018D0 (en)	2005-02-26	2005-02-26	Quinazoline derivatives
GB0506657A GB0506657D0 (en)	2005-03-31	2005-03-31	Quinazoline derivatives
GB0524001A GB0524001D0 (en)	2005-11-25	2005-11-25	Quinazoline derivatives
PCT/GB2006/000656 WO2006090163A1 (en)	2005-02-26	2006-02-24	Quinazoline derivatives as tyrosine kinase inhibitors

Publications (1)

Publication Number	Publication Date
NO20073878L true NO20073878L (no)	2007-10-23

Family

ID=36390222

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20073878A NO20073878L (no)	2005-02-26	2007-07-24	Kinazolinderivater som tyrosin kinase inhibitorer

Country Status (15)

Country	Link
US (1)	US8735410B2 (de)
EP (1)	EP1856095B1 (de)
JP (1)	JP5054544B2 (de)
KR (1)	KR20070107151A (de)
AR (1)	AR055564A1 (de)
AT (1)	ATE521603T1 (de)
AU (1)	AU2006217738A1 (de)
BR (1)	BRPI0607432A2 (de)
CA (1)	CA2599210A1 (de)
IL (1)	IL184798A0 (de)
MX (1)	MX2007010399A (de)
NO (1)	NO20073878L (de)
TW (1)	TW200640904A (de)
UY (1)	UY29398A1 (de)
WO (1)	WO2006090163A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2005026150A1 (en)	2003-09-16	2005-03-24	Astrazeneca Ab	Quinazoline derivatives as tyrosine kinase inhibitors
GB0326459D0 (en)	2003-11-13	2003-12-17	Astrazeneca Ab	Quinazoline derivatives
ATE413389T1 (de)	2004-02-03	2008-11-15	Astrazeneca Ab	Chinazolinderivate
EP2346507A1 (de)	2008-09-03	2011-07-27	Boehringer Ingelheim International GmbH	Verwendung von chinazolin-derivaten zur behandlung von viruserkrankungen
KR20140096571A (ko) *	2013-01-28	2014-08-06	한미약품 주식회사	1-(4-(4-(3,4-디클로로-2-플루오로페닐아미노)-7-메톡시퀴나졸린-6-일옥시)피페리딘-1-일)프로프-2-엔-1-온의 제조방법
CN103288759B (zh) *	2013-05-16	2015-05-20	苏州明锐医药科技有限公司	达克米替尼的制备方法
WO2016123706A1 (en) *	2015-02-03	2016-08-11	Trillium Therapeutics Inc.	Novel fluorinated derivatives as egfr inhibitors useful for treating cancers
WO2019062637A1 (zh)	2017-09-28	2019-04-04	南京明德新药研发股份有限公司	喹啉衍生物及其作为酪氨酸激酶抑制剂的应用
KR102802129B1 (ko) *	2018-09-14	2025-05-02	한미약품 주식회사	퀴나졸린 화합물 및 이의 염산염의 결정 형태

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BRPI0414532B1 (pt)	2003-09-19	2018-06-05	Astrazeneca Ab	Composto derivado de quinazolina, processo para preparar 0 mesmo, composição farmaceutica, e, uso de um composto derivado de quinazolina
DE602004004811T2 (de)	2003-09-19	2007-11-22	Astrazeneca Ab	Chinazolinderivate
MXPA06003341A (es)	2003-09-25	2006-06-08	Astrazeneca Ab	Derivados de quinazolina.

2006
- 2006-02-24 AU AU2006217738A patent/AU2006217738A1/en not_active Abandoned
- 2006-02-24 AR ARP060100689A patent/AR055564A1/es unknown
- 2006-02-24 MX MX2007010399A patent/MX2007010399A/es not_active Application Discontinuation
- 2006-02-24 BR BRPI0607432-4A patent/BRPI0607432A2/pt not_active IP Right Cessation
- 2006-02-24 US US11/884,923 patent/US8735410B2/en not_active Expired - Fee Related
- 2006-02-24 KR KR1020077021853A patent/KR20070107151A/ko not_active Withdrawn
- 2006-02-24 AT AT06709888T patent/ATE521603T1/de not_active IP Right Cessation
- 2006-02-24 JP JP2007556662A patent/JP5054544B2/ja not_active Expired - Fee Related
- 2006-02-24 WO PCT/GB2006/000656 patent/WO2006090163A1/en not_active Ceased
- 2006-02-24 TW TW095106212A patent/TW200640904A/zh unknown
- 2006-02-24 UY UY29398A patent/UY29398A1/es unknown
- 2006-02-24 EP EP06709888A patent/EP1856095B1/de not_active Expired - Lifetime
- 2006-02-24 CA CA002599210A patent/CA2599210A1/en not_active Abandoned
2007
- 2007-07-23 IL IL184798A patent/IL184798A0/en unknown
- 2007-07-24 NO NO20073878A patent/NO20073878L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
BRPI0607432A2 (pt)	2009-09-01
KR20070107151A (ko)	2007-11-06
AR055564A1 (es)	2007-08-22
TW200640904A (en)	2006-12-01
MX2007010399A (es)	2007-09-25
US20110152297A1 (en)	2011-06-23
AU2006217738A1 (en)	2006-08-31
EP1856095A1 (de)	2007-11-21
ATE521603T1 (de)	2011-09-15
UY29398A1 (es)	2006-10-02
IL184798A0 (en)	2007-12-03
EP1856095B1 (de)	2011-08-24
JP5054544B2 (ja)	2012-10-24
JP2008531536A (ja)	2008-08-14
US8735410B2 (en)	2014-05-27
CA2599210A1 (en)	2006-08-31
WO2006090163A1 (en)	2006-08-31

Legal Events

Date	Code	Title	Description
2010-09-27	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO20061323L (no)	2006-06-09	Kinazolinderivater
NO20061322L (no)	2006-06-15	Kinazolinderivater som tyrosin kinase inhibitorer
NO20061327L (no)	2006-04-05	Kinazolinderivater
NO20092737L (no)	2009-09-18	Substituerte pyrazolo-kinazolinderivater, fremgangsmate for deres fremstilling og deres anvendelse som kinase-inhibitorer
NO20061743L (no)	2006-06-21	Kinazolinderivater
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