NO20073878L - Kinazolinderivater som tyrosin kinase inhibitorer - Google Patents

Kinazolinderivater som tyrosin kinase inhibitorer

Info

Publication number: NO20073878L
Authority: NO; Norway
Prior art keywords: quinazoline derivatives; tyrosine kinase; kinase inhibitors; formula; medicament
Prior art date: 2005-02-26

Application number

NO20073878A

Other languages

English (en)

Norwegian (no)

Inventor

Richard Anthony Storey

Alleyn Plowright

Christopher Thomas Halsall

Laurent Francois And Hennequin

Kieran Lennon

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-02-26

Filing date

2007-07-24

Publication date

2007-10-23

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36390222&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20073878(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2005-02-26 Priority claimed from GB0504018A external-priority patent/GB0504018D0/en

2005-03-31 Priority claimed from GB0506657A external-priority patent/GB0506657D0/en

2005-11-25 Priority claimed from GB0524001A external-priority patent/GB0524001D0/en

2007-07-24 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2007-10-23 Publication of NO20073878L publication Critical patent/NO20073878L/no

Links

125000002294 quinazolinyl group Chemical class N1=C(N=CC2=CC=CC=C12)* 0.000 title abstract 3
229940121358 tyrosine kinase inhibitor Drugs 0.000 title 1
239000005483 tyrosine kinase inhibitor Substances 0.000 title 1
102000001301 EGF receptor Human genes 0.000 abstract 1
108060006698 EGF receptor Proteins 0.000 abstract 1
206010028980 Neoplasm Diseases 0.000 abstract 1
102000004022 Protein-Tyrosine Kinases Human genes 0.000 abstract 1
108090000412 Protein-Tyrosine Kinases Proteins 0.000 abstract 1
230000001028 anti-proliverative effect Effects 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
102000052116 epidermal growth factor receptor activity proteins Human genes 0.000 abstract 1
108700015053 epidermal growth factor receptor activity proteins Proteins 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
230000001404 mediated effect Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
YOHYSYJDKVYCJI-UHFFFAOYSA-N n-[3-[[6-[3-(trifluoromethyl)anilino]pyrimidin-4-yl]amino]phenyl]cyclopropanecarboxamide Chemical compound FC(F)(F)C1=CC=CC(NC=2N=CN=C(NC=3C=C(NC(=O)C4CC4)C=CC=3)C=2)=C1 YOHYSYJDKVYCJI-UHFFFAOYSA-N 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO20073878A 2005-02-26 2007-07-24 Kinazolinderivater som tyrosin kinase inhibitorer NO20073878L (no)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB0504018A GB0504018D0 (en)	2005-02-26	2005-02-26	Quinazoline derivatives
GB0506657A GB0506657D0 (en)	2005-03-31	2005-03-31	Quinazoline derivatives
GB0524001A GB0524001D0 (en)	2005-11-25	2005-11-25	Quinazoline derivatives
PCT/GB2006/000656 WO2006090163A1 (en)	2005-02-26	2006-02-24	Quinazoline derivatives as tyrosine kinase inhibitors

Publications (1)

Publication Number	Publication Date
NO20073878L true NO20073878L (no)	2007-10-23

Family

ID=36390222

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20073878A NO20073878L (no)	2005-02-26	2007-07-24	Kinazolinderivater som tyrosin kinase inhibitorer

Country Status (15)

Country	Link
US (1)	US8735410B2 (pt)
EP (1)	EP1856095B1 (pt)
JP (1)	JP5054544B2 (pt)
KR (1)	KR20070107151A (pt)
AR (1)	AR055564A1 (pt)
AT (1)	ATE521603T1 (pt)
AU (1)	AU2006217738A1 (pt)
BR (1)	BRPI0607432A2 (pt)
CA (1)	CA2599210A1 (pt)
IL (1)	IL184798A0 (pt)
MX (1)	MX2007010399A (pt)
NO (1)	NO20073878L (pt)
TW (1)	TW200640904A (pt)
UY (1)	UY29398A1 (pt)
WO (1)	WO2006090163A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MXPA06002964A (es)	2003-09-16	2006-06-14	Astrazeneca Ab	Derivados de quinazolina como inhibidores de cinasa de tirosina.
GB0326459D0 (en)	2003-11-13	2003-12-17	Astrazeneca Ab	Quinazoline derivatives
DE602005010824D1 (de)	2004-02-03	2008-12-18	Astrazeneca Ab	Chinazolinderivate
CA2735875A1 (en)	2008-09-03	2010-03-11	Boehringer Ingelheim International Gmbh	Use of quinazoline derivatives for the treatment of viral diseases
KR20140096571A (ko) *	2013-01-28	2014-08-06	한미약품 주식회사	1-(4-(4-(3,4-디클로로-2-플루오로페닐아미노)-7-메톡시퀴나졸린-6-일옥시)피페리딘-1-일)프로프-2-엔-1-온의 제조방법
CN103288759B (zh) *	2013-05-16	2015-05-20	苏州明锐医药科技有限公司	达克米替尼的制备方法
AU2016214923A1 (en) *	2015-02-03	2017-08-24	Trillium Therapeutics Inc.	Novel fluorinated derivatives as EGFR inhibitors useful for treating cancers
JP7177829B2 (ja) *	2017-09-28	2022-11-24	チョンチンファーマシューティカルインダストリアルリサーチインスティテュートカンパニーリミティド	キノリン誘導体およびチロシンキナーゼ阻害剤としてのそれらの応用
EP3849964A4 (en) *	2018-09-14	2022-06-08	Hanmi Pharmaceutical Co., Ltd.	CRYSTALLINE FORMS OF A QUINAZOLE COMPOUND AND ITS HYDROCHLORIDE SALTS

Family Cites Families (84)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3985749A (en) *	1975-12-22	1976-10-12	Eastman Kodak Company	Process for preparation of 4-aminoquinazoline
JPS5538325A (en)	1978-09-11	1980-03-17	Sankyo Co Ltd	4-anilinoquinazoline derivative and its preparation
US4335127A (en) *	1979-01-08	1982-06-15	Janssen Pharmaceutica, N.V.	Piperidinylalkyl quinazoline compounds, composition and method of use
US4332420A (en)	1980-01-11	1982-06-01	Coski William D	Reciprocably supported dual drive member and features thereof
GB2160201B (en)	1984-06-14	1988-05-11	Wyeth John & Brother Ltd	Quinazoline and cinnoline derivatives
KR910006138B1 (ko)	1986-09-30	1991-08-16	에자이 가부시끼가이샤	환상아민 유도체
IL89029A (en)	1988-01-29	1993-01-31	Lilly Co Eli	Fungicidal quinoline and cinnoline derivatives, compositions containing them, and fungicidal methods of using them
US4921863A (en) *	1988-02-17	1990-05-01	Eisai Co., Ltd.	Cyclic amine derivatives
CA1340821C (en) *	1988-10-06	1999-11-16	Nobuyuki Fukazawa	Heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components
US5252586A (en) *	1990-09-28	1993-10-12	The Du Pont Merck Pharmaceutical Company	Ether derivatives of alkyl piperidines and pyrrolidines as antipsychotic agents
DE4105503A1 (de)	1991-02-19	1992-08-20	Jenapharm Gmbh	Ausgangsverbindungen zur herstellung von calcitriol sowie dessen abkoemmlingen, verfahren zur herstellung dieser ausgangsverbindungen sowie zwischenprodukte fuer dieses verfahren
US5721237A (en)	1991-05-10	1998-02-24	Rhone-Poulenc Rorer Pharmaceuticals Inc.	Protein tyrosine kinase aryl and heteroaryl quinazoline compounds having selective inhibition of HER-2 autophosphorylation properties
US5710158A (en)	1991-05-10	1998-01-20	Rhone-Poulenc Rorer Pharmaceuticals Inc.	Aryl and heteroaryl quinazoline compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
AU658646B2 (en)	1991-05-10	1995-04-27	Rhone-Poulenc Rorer International (Holdings) Inc.	Bis mono-and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
NZ243082A (en)	1991-06-28	1995-02-24	Ici Plc	4-anilino-quinazoline derivatives; pharmaceutical compositions, preparatory processes, and use thereof
PT100905A (pt)	1991-09-30	1994-02-28	Eisai Co Ltd	Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem
US5187168A (en)	1991-10-24	1993-02-16	American Home Products Corporation	Substituted quinazolines as angiotensin II antagonists
AU661533B2 (en) *	1992-01-20	1995-07-27	Astrazeneca Ab	Quinazoline derivatives
WO1993017682A1 (en)	1992-03-04	1993-09-16	Abbott Laboratories	Angiotensin ii receptor antagonists
GB9323290D0 (en)	1992-12-10	1994-01-05	Zeneca Ltd	Quinazoline derivatives
AU680004B2 (en)	1993-05-26	1997-07-17	Syntex (U.S.A.) Inc.	Novel 1-phenylalkanone 5-HT4 receptor ligands
US5395846A (en)	1993-06-25	1995-03-07	Rhone-Poulenc Rorer Pharmaceuticals Inc.	Amino Bi- and tri-carbocyclic aklane bis-aryl squalene synthase inhibitors
GB9314893D0 (en)	1993-07-19	1993-09-01	Zeneca Ltd	Quinazoline derivatives
GB9314884D0 (en)	1993-07-19	1993-09-01	Zeneca Ltd	Tricyclic derivatives
AU2096895A (en)	1994-03-07	1995-09-25	Sugen, Incorporated	Receptor tyrosine kinase inhibitors for inhibiting cell proliferative disorders and compositions thereof
GB9510757D0 (en)	1994-09-19	1995-07-19	Wellcome Found	Therapeuticaly active compounds
TW321649B (pt) *	1994-11-12	1997-12-01	Zeneca Ltd
GB2295387A (en)	1994-11-23	1996-05-29	Glaxo Inc	Quinazoline antagonists of alpha 1c adrenergic receptors
GB9424233D0 (en)	1994-11-30	1995-01-18	Zeneca Ltd	Quinazoline derivatives
DE69522717T2 (de)	1995-03-30	2002-02-14	Pfizer Inc., New York	Chinazolinderivate
GB9508538D0 (en)	1995-04-27	1995-06-14	Zeneca Ltd	Quinazoline derivatives
EP0824525B1 (en)	1995-04-27	2001-06-13	AstraZeneca AB	Quinazoline derivatives
GB9508535D0 (en)	1995-04-27	1995-06-14	Zeneca Ltd	Quinazoline derivative
GB9508565D0 (en)	1995-04-27	1995-06-14	Zeneca Ltd	Quiazoline derivative
GB9508537D0 (en)	1995-04-27	1995-06-14	Zeneca Ltd	Quinazoline derivatives
US5747498A (en) *	1996-05-28	1998-05-05	Pfizer Inc.	Alkynyl and azido-substituted 4-anilinoquinazolines
US6046206A (en) *	1995-06-07	2000-04-04	Cell Pathways, Inc.	Method of treating a patient having a precancerous lesions with amide quinazoline derivatives
GB9624482D0 (en) *	1995-12-18	1997-01-15	Zeneca Phaema S A	Chemical compounds
BR9702049B1 (pt) *	1996-01-31	2010-08-10		sistema distribuidor contendo dois compartimentos para a dosagem simultánea de duas composições aquosas.
US5760041A (en)	1996-02-05	1998-06-02	American Cyanamid Company	4-aminoquinazoline EGFR Inhibitors
GB9603095D0 (en) *	1996-02-14	1996-04-10	Zeneca Ltd	Quinazoline derivatives
GB9607729D0 (en) *	1996-04-13	1996-06-19	Zeneca Ltd	Quinazoline derivatives
US6004967A (en) *	1996-09-13	1999-12-21	Sugen, Inc.	Psoriasis treatment with quinazoline compounds
GB9718972D0 (en) *	1996-09-25	1997-11-12	Zeneca Ltd	Chemical compounds
US6225318B1 (en) *	1996-10-17	2001-05-01	Pfizer Inc	4-aminoquinazolone derivatives
EP0837063A1 (en)	1996-10-17	1998-04-22	Pfizer Inc.	4-Aminoquinazoline derivatives
US5929080A (en) *	1997-05-06	1999-07-27	American Cyanamid Company	Method of treating polycystic kidney disease
JP4245682B2 (ja)	1997-12-25	2009-03-25	協和発酵キリン株式会社	キノリン誘導体、イソキノリン誘導体、およびシンノリン誘導体、並びに抗炎症剤および抗アレルギー剤
US6384223B1 (en) *	1998-07-30	2002-05-07	American Home Products Corporation	Substituted quinazoline derivatives
US6297258B1 (en) *	1998-09-29	2001-10-02	American Cyanamid Company	Substituted 3-cyanoquinolines
KR20020068261A (ko) *	1999-02-27	2002-08-27	베링거 잉겔하임 파르마 카게	티로신 키나제에 의해 매개되는 신호 변환에 대한 억제효과를 갖는 4-아미노-퀴나졸린 및 퀴놀린 유도체
US6080747A (en) *	1999-03-05	2000-06-27	Hughes Institute	JAK-3 inhibitors for treating allergic disorders
DE19911509A1 (de) *	1999-03-15	2000-09-21	Boehringer Ingelheim Pharma	Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
WO2000068203A1 (en)	1999-05-07	2000-11-16	Takeda Chemical Industries, Ltd.	Cyclic compounds and uses thereof
US6126917A (en) *	1999-06-01	2000-10-03	Hadasit Medical Research Services And Development Ltd.	Epidermal growth factor receptor binding compounds for positron emission tomography
CA2375259C (en) *	1999-06-21	2009-04-28	Boehringer Ingelheim Pharma Kg	Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them
WO2001087293A1 (en)	2000-05-19	2001-11-22	Takeda Chemical Industries, Ltd.	-secretase inhibitors
DE10042060A1 (de)	2000-08-26	2002-03-07	Boehringer Ingelheim Pharma	Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
US6656946B2 (en) *	2000-08-26	2003-12-02	Boehringer Ingelheim Pharma Kg	Aminoquinazolines which inhibit signal transduction mediated by tyrosine kinases
DE10042062A1 (de)	2000-08-26	2002-03-07	Boehringer Ingelheim Pharma	Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Hertellung
DE10042058A1 (de)	2000-08-26	2002-03-07	Boehringer Ingelheim Pharma	Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
US6617329B2 (en) *	2000-08-26	2003-09-09	Boehringer Ingelheim Pharma Kg	Aminoquinazolines and their use as medicaments
US6740651B2 (en) *	2000-08-26	2004-05-25	Boehringer Ingelheim Pharma Kg	Aminoquinazolines which inhibit signal transduction mediated by tyrosine kinases
US6653305B2 (en) *	2000-08-26	2003-11-25	Boehringer Ingelheim Pharma Kg	Bicyclic heterocycles, pharmaceutical compositions containing them, their use, and processes for preparing them
DE10042061A1 (de)	2000-08-26	2002-03-07	Boehringer Ingelheim Pharma	Bicyclische Heterocyclen,diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
US20020082270A1 (en) *	2000-08-26	2002-06-27	Frank Himmelsbach	Aminoquinazolines which inhibit signal transduction mediated by tyrosine kinases
DE10042059A1 (de)	2000-08-26	2002-03-07	Boehringer Ingelheim Pharma	Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
US20030158196A1 (en) *	2002-02-16	2003-08-21	Boehringer Ingelheim Pharma Gmbh Co. Kg	Pharmaceutical compositions based on anticholinergics and EGFR kinase inhibitors
US7019012B2 (en) *	2000-12-20	2006-03-28	Boehringer Ingelheim International Pharma Gmbh & Co. Kg	Quinazoline derivatives and pharmaceutical compositions containing them
NZ516873A (en)	2001-02-12	2003-11-28	Warner Lambert Co	Compositions containing retinoids and erb inhibitors and their use in inhibiting retinoid skin damage
CA2442742A1 (en)	2001-02-21	2002-08-29	Mitsubishi Pharma Corporation	Quinazoline derivatives
US6562319B2 (en) *	2001-03-12	2003-05-13	Yissum Research Development Company Of The Hebrew University Of Jerusalem	Radiolabeled irreversible inhibitors of epidermal growth factor receptor tyrosine kinase and their use in radioimaging and radiotherapy
US20040176361A1 (en) *	2001-05-23	2004-09-09	Masakazu Fujio	Fused heterocyclic compound and medicinal use thereof
DE10204462A1 (de) *	2002-02-05	2003-08-07	Boehringer Ingelheim Pharma	Verwendung von Tyrosinkinase-Inhibitoren zur Behandlung inflammatorischer Prozesse
TW200813014A (en) *	2002-03-28	2008-03-16	Astrazeneca Ab	Quinazoline derivatives
KR101064530B1 (ko) *	2002-03-30	2011-09-14	베링거 잉겔하임 파르마 게엠베하 운트 코 카게	티로신 키나아제 억제제로서의 4-(ｎ-페닐아미노)-퀴나졸린/퀴놀린, 이를 함유하는 약제학적 조성물 및 이의 제조방법
US6924285B2 (en) *	2002-03-30	2005-08-02	Boehringer Ingelheim Pharma Gmbh & Co.	Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them
US20040044014A1 (en) *	2002-04-19	2004-03-04	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for the preparation thereof
DE10334226A1 (de) *	2003-07-28	2005-02-17	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Verwendung von Tyrosinkinase-Inhibitoren zur Behandlung inflammatorischer Prozesse
JP2007500177A (ja) *	2003-07-29	2007-01-11	アストラゼネカアクチボラグ	チロシンキナーゼ阻害剤としてのピペリジルキナゾリン誘導体
GB0317665D0 (en) *	2003-07-29	2003-09-03	Astrazeneca Ab	Qinazoline derivatives
ATE353888T1 (de) *	2003-09-19	2007-03-15	Astrazeneca Ab	Chinazolinderivate
US8318752B2 (en) *	2003-09-19	2012-11-27	Astrazeneca Ab	4-(3-chloro-2-fluoroanilino)-7-methoxy-6-{[1-(N-methylcarbamoyl-methyl)piperidin-4-yl]oxy}quinazoline, its pharmaceutically acceptable salts, and pharmaceutical compositions comprising the same
EP1670786A1 (en) *	2003-09-25	2006-06-21	Astrazeneca AB	Quinazoline derivatives

2006
- 2006-02-24 AT AT06709888T patent/ATE521603T1/de not_active IP Right Cessation
- 2006-02-24 UY UY29398A patent/UY29398A1/es unknown
- 2006-02-24 EP EP06709888A patent/EP1856095B1/en not_active Expired - Lifetime
- 2006-02-24 CA CA002599210A patent/CA2599210A1/en not_active Abandoned
- 2006-02-24 BR BRPI0607432-4A patent/BRPI0607432A2/pt not_active IP Right Cessation
- 2006-02-24 KR KR1020077021853A patent/KR20070107151A/ko not_active Withdrawn
- 2006-02-24 WO PCT/GB2006/000656 patent/WO2006090163A1/en not_active Ceased
- 2006-02-24 AU AU2006217738A patent/AU2006217738A1/en not_active Abandoned
- 2006-02-24 TW TW095106212A patent/TW200640904A/zh unknown
- 2006-02-24 JP JP2007556662A patent/JP5054544B2/ja not_active Expired - Fee Related
- 2006-02-24 US US11/884,923 patent/US8735410B2/en not_active Expired - Fee Related
- 2006-02-24 MX MX2007010399A patent/MX2007010399A/es not_active Application Discontinuation
- 2006-02-24 AR ARP060100689A patent/AR055564A1/es unknown
2007
- 2007-07-23 IL IL184798A patent/IL184798A0/en unknown
- 2007-07-24 NO NO20073878A patent/NO20073878L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
US20110152297A1 (en)	2011-06-23
AU2006217738A1 (en)	2006-08-31
EP1856095A1 (en)	2007-11-21
CA2599210A1 (en)	2006-08-31
EP1856095B1 (en)	2011-08-24
UY29398A1 (es)	2006-10-02
KR20070107151A (ko)	2007-11-06
JP5054544B2 (ja)	2012-10-24
JP2008531536A (ja)	2008-08-14
BRPI0607432A2 (pt)	2009-09-01
AR055564A1 (es)	2007-08-22
TW200640904A (en)	2006-12-01
WO2006090163A1 (en)	2006-08-31
MX2007010399A (es)	2007-09-25
US8735410B2 (en)	2014-05-27
ATE521603T1 (de)	2011-09-15
IL184798A0 (en)	2007-12-03

Legal Events

Date	Code	Title	Description
2010-09-27	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO20061323L (no)	2006-06-09	Kinazolinderivater
NO20061322L (no)	2006-06-15	Kinazolinderivater som tyrosin kinase inhibitorer
NO20073878L (no)	2007-10-23	Kinazolinderivater som tyrosin kinase inhibitorer
NO20061327L (no)	2006-04-05	Kinazolinderivater
NO20092737L (no)	2009-09-18	Substituerte pyrazolo-kinazolinderivater, fremgangsmate for deres fremstilling og deres anvendelse som kinase-inhibitorer
NO20061743L (no)	2006-06-21	Kinazolinderivater
NO20066081L (no)	2007-02-20	Kinazolinderivater som erbB-reseptortyrosinkinaser
NO20090631L (no)	2009-03-16	Morpholin pyrimidin derivativer anvendelige i behandlingen av proliferative lidelser
SE0402735D0 (sv)	2004-11-09	Novel compounds
EA200870373A1 (ru)	2009-04-28	Пиридил- и пиримидинилзамещённые производные пиррола, тиофена и фурана в качестве ингибиторов киназ
NO20070917L (no)	2007-03-19	Imidazotriaziner som protein-kinaseinhibitorer
CY1118969T1 (el)	2018-01-10	Ενωσεις πυριμιδινο-2-αμινης και η χρηση τους ως αναστολεις των κινασων jak
NO20075641L (no)	2007-11-20	Kroman og kromenderivater og ders anvendelse
NO20085217L (no)	2009-01-12	Effektive pyrimidinderivater i behandlingen av kreft
NO20082643L (no)	2008-09-01	Isokinolinaminopyrazolderivater, deres fremstilling og anvendelse som farmasoytiske midler for behandling av kreft
EA201000830A1 (ru)	2011-02-28	Производные пиримидина для лечения астмы, хобл, аллергического ринита, аллергического конъюнктивита, атопического дерматита, рака, гепатита в, гепатита с, вич, впч, бактериальных инфекций и дерматоза
EA201170249A1 (ru)	2011-10-31	3,4-диарилпиразолы в качестве ингибиторов протеинкиназ
NO20071246L (no)	2007-05-24	Kinazolinonderivater og deres anvendelse som B-RAF-inhibitorer.
PH12013501594A1 (en)	2014-05-12	Substituted indazole derivatives active as kinase inhibitors
ATE514699T1 (de)	2011-07-15	Substituierte pyrrolopyrazolderivate als kinaseinhibitoren
SG170101A1 (en)	2011-04-29	2-pyrazinone derivatives for the treatment of disease or condition in which inhibition of neutrophil elastase activity is beneficial.
WO2008002244A3 (en)	2008-02-14	Imidazol-pyrimidine derivatives for treatment of diseases related to glycogen synthase kinase (gsk3)
WO2008002245A3 (en)	2008-02-14	Imidazol-pyrimidine derivatives for treatment of diseases related to glycogen synthase kinase (gsk3)
NO20085257L (no)	2009-01-19	Purinonderivater som HM74a-agonister
NO20065727L (no)	2006-12-12	Pyrrolinhibitorer av erk-proteinkinase, syntese derav og deres mellomprodukter