NO20074576L - Radiolabeled Gallium Complexes, Methods for Synthesis and Use For Pet Imaging of EGFR Expression in Malignant Tumors - Google Patents

Radiolabeled Gallium Complexes, Methods for Synthesis and Use For Pet Imaging of EGFR Expression in Malignant Tumors

Info

Publication number: NO20074576L
Authority: NO; Norway
Prior art keywords: synthesis; methods; malignant tumors; pet imaging; egfr expression
Prior art date: 2005-02-22

Application number

NO20074576A

Other languages

English (en)

Norwegian (no)

Inventor

Vladimir Tolmachev

Bengt Langstrom

Asa Liljegren Sundberg

Irina Velikyan

Original Assignee

Ge Healthcare Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-02-22

Filing date

2007-09-10

Publication date

2007-11-20

2007-09-10 Application filed by Ge Healthcare Ltd filed Critical Ge Healthcare Ltd

2007-11-20 Publication of NO20074576L publication Critical patent/NO20074576L/no

Links

238000000034 method Methods 0.000 title abstract 3
102000052116 epidermal growth factor receptor activity proteins Human genes 0.000 title abstract 2
108700015053 epidermal growth factor receptor activity proteins Proteins 0.000 title abstract 2
238000003384 imaging method Methods 0.000 title abstract 2
YOHYSYJDKVYCJI-UHFFFAOYSA-N n-[3-[[6-[3-(trifluoromethyl)anilino]pyrimidin-4-yl]amino]phenyl]cyclopropanecarboxamide Chemical compound FC(F)(F)C1=CC=CC(NC=2N=CN=C(NC=3C=C(NC(=O)C4CC4)C=CC=3)C=2)=C1 YOHYSYJDKVYCJI-UHFFFAOYSA-N 0.000 title abstract 2
230000015572 biosynthetic process Effects 0.000 title 1
201000011510 cancer Diseases 0.000 title 1
150000002258 gallium Chemical class 0.000 title 1
238000003786 synthesis reaction Methods 0.000 title 1
GYHNNYVSQQEPJS-UHFFFAOYSA-N Gallium Chemical compound [Ga] GYHNNYVSQQEPJS-UHFFFAOYSA-N 0.000 abstract 2
229910052733 gallium Inorganic materials 0.000 abstract 2
238000002600 positron emission tomography Methods 0.000 abstract 2
206010028980 Neoplasm Diseases 0.000 abstract 1
230000004913 activation Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000002018 overexpression Effects 0.000 abstract 1
229940121896 radiopharmaceutical Drugs 0.000 abstract 1
239000012217 radiopharmaceutical Substances 0.000 abstract 1
230000002799 radiopharmaceutical effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1282—Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Optics & Photonics (AREA)
Veterinary Medicine (AREA)
Physics & Mathematics (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Zoology (AREA)
Heart & Thoracic Surgery (AREA)
General Chemical & Material Sciences (AREA)
Dispersion Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Toxicology (AREA)
Molecular Biology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

NO20074576A 2005-02-22 2007-09-10 Radiolabeled Gallium Complexes, Methods for Synthesis and Use For Pet Imaging of EGFR Expression in Malignant Tumors NO20074576L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US65513905P	2005-02-22	2005-02-22
PCT/IB2006/000345 WO2006090232A2 (en)	2005-02-22	2006-02-21	Radiolabeled gallium complexes, methods for synthesis and use for pet imaging of egfr epxression in malignant tumors

Publications (1)

Publication Number	Publication Date
NO20074576L true NO20074576L (no)	2007-11-20

Family

ID=36927800

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20074576A NO20074576L (no)	2005-02-22	2007-09-10	Radiolabeled Gallium Complexes, Methods for Synthesis and Use For Pet Imaging of EGFR Expression in Malignant Tumors

Country Status (12)

Country	Link
US (2)	US20060188441A1 (pt)
EP (1)	EP1850881A2 (pt)
JP (1)	JP2008531988A (pt)
KR (1)	KR20070106731A (pt)
CN (1)	CN101443051A (pt)
AU (1)	AU2006217612A1 (pt)
BR (1)	BRPI0608217A2 (pt)
CA (1)	CA2598863A1 (pt)
MX (1)	MX2007010116A (pt)
NO (1)	NO20074576L (pt)
RU (1)	RU2007131538A (pt)
WO (1)	WO2006090232A2 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8926945B2 (en) *	2005-10-07	2015-01-06	Guerbet	Compounds comprising a biological target recognizing part, coupled to a signal part capable of complexing gallium
FR2899585B1 (fr) *	2006-04-05	2012-06-15	Guerbet Sa	Composes comprenant une partie de reconnaissance d'une cible biologique, couplee a une partie de signal capable de complexer le gallium
FR2980193B1 (fr) *	2011-09-15	2014-02-14	Guerbet Sa	Procede de purification de produits de contraste
JP6185262B2 (ja) *	2013-03-07	2017-08-23	日本メジフィジックス株式会社	核医学骨画像解析技術
GB201405591D0 (en) *	2014-03-28	2014-05-14	Ge Healthcare Ltd	Heatseal
CN107405538B (zh) *	2015-01-30	2021-06-15	高级催化剂应用品国际有限公司	用于从来源于68Ge/68Ga发生器的洗脱物纯化Ga-68的工艺和用于所述工艺中的色谱柱
WO2021234741A1 (en)	2020-05-18	2021-11-25	C.M.S. S.P.A.	Microwave device for the rapid labelling of in kit-formulated radiopharmaceuticals
JP2023157161A (ja) *	2022-04-14	2023-10-26	三菱重工航空エンジン株式会社	遮熱コーティングの施工方法及び耐熱部材
US20250289832A1 (en) *	2022-04-27	2025-09-18	Nihon Medi-Physics Co., Ltd.	Method for producing radioactive metal complex

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4288424A (en) *	1979-01-15	1981-09-08	Massachusetts Institute Of Technology	Generator for ionic gallium-68 based on column chromatography
US4330507A (en) *	1980-06-11	1982-05-18	New England Nuclear Corporation	Method and system for generating and collecting gallium-68 using alkaline eluant
DK0436005T3 (da) *	1989-07-20	1995-07-03	Sandoz Ltd	Mærkede polypeptidderivater
US5686410A (en) *	1989-07-20	1997-11-11	Novartis Ag	Polypeptide derivatives
WO1993009816A1 (en) *	1991-11-14	1993-05-27	Battelle Memorial Institute	Method for diagnosing and treating cancer
DE4231622C2 (de) *	1992-09-22	1996-09-05	Bakelite Ag	Verfahren zur Herstellung von Metallneutralkomplexen mit hoher Koordinationszahl und deren Verwendung
US6071490A (en) *	1998-05-07	2000-06-06	Immunomedics, Inc.	Position emission tomography using gallium-68 chelates
EP1389090A2 (en) *	2001-04-26	2004-02-18	Board of Regents, The University of Texas System	Diagnostic imaging compositions, their methods of synthesis and use
GB0308408D0 (en) *	2003-04-11	2003-05-21	Amersham Plc	Microwave activation
WO2004096254A2 (en) *	2003-05-02	2004-11-11	Xpression Antibody Therapeutics, Inc.	Transferrin conjugates for tumor treatment
US20050085417A1 (en) *	2003-10-16	2005-04-21	Thomas Jefferson University	Compounds and methods for diagnostic imaging and therapy

2006
- 2006-02-21 WO PCT/IB2006/000345 patent/WO2006090232A2/en not_active Ceased
- 2006-02-21 EP EP06710418A patent/EP1850881A2/en not_active Withdrawn
- 2006-02-21 CA CA002598863A patent/CA2598863A1/en not_active Abandoned
- 2006-02-21 KR KR1020077019093A patent/KR20070106731A/ko not_active Withdrawn
- 2006-02-21 RU RU2007131538/15A patent/RU2007131538A/ru unknown
- 2006-02-21 US US11/358,681 patent/US20060188441A1/en not_active Abandoned
- 2006-02-21 BR BRPI0608217A patent/BRPI0608217A2/pt not_active IP Right Cessation
- 2006-02-21 AU AU2006217612A patent/AU2006217612A1/en not_active Abandoned
- 2006-02-21 CN CNA2006800056439A patent/CN101443051A/zh active Pending
- 2006-02-21 JP JP2007555725A patent/JP2008531988A/ja active Pending
- 2006-02-21 MX MX2007010116A patent/MX2007010116A/es unknown
2007
- 2007-09-10 NO NO20074576A patent/NO20074576L/no not_active Application Discontinuation
2011
- 2011-01-21 US US13/010,870 patent/US20110117012A1/en not_active Abandoned

Also Published As

Publication number	Publication date
WO2006090232A3 (en)	2007-04-05
CA2598863A1 (en)	2006-08-31
AU2006217612A1 (en)	2006-08-31
KR20070106731A (ko)	2007-11-05
BRPI0608217A2 (pt)	2016-10-11
MX2007010116A (es)	2007-10-12
US20060188441A1 (en)	2006-08-24
CN101443051A (zh)	2009-05-27
RU2007131538A (ru)	2009-03-27
EP1850881A2 (en)	2007-11-07
WO2006090232A2 (en)	2006-08-31
US20110117012A1 (en)	2011-05-19
JP2008531988A (ja)	2008-08-14

Legal Events

Date	Code	Title	Description
2012-10-01	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO20074576L (no)	2007-11-20	Radiolabeled Gallium Complexes, Methods for Synthesis and Use For Pet Imaging of EGFR Expression in Malignant Tumors
WO2008045604A3 (en)	2009-02-26	Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
ATE541571T1 (de)	2012-02-15	Diarylhydantoin-verbindung
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AU2003205077A1 (en)	2003-07-30	Imaging agents and methods of imaging naaladase of psma
BG108497A (en)	2005-03-31	Solid-phase nucleophilic fluorination
WO2005123993A8 (en)	2007-03-15	Phage microarray profiling of the humoral response to disease
WO2009052970A3 (en)	2009-07-02	Compounds for use in imaging, diagnosing, and/or treatment of diseases of the central nervous system or of tumors
BR0306715A (pt)	2004-12-28	Métodos para diagnóstico e tratamento de tumores
WO2010039609A3 (en)	2010-09-10	Conjugates of hexose and metal coordinating compounds for imaging purposes
MX2011010295A (es)	2012-03-26	Reactivos de radiomarcado y metodos.
GB0308408D0 (en)	2003-05-21	Microwave activation
WO2008024826A3 (en)	2008-11-20	Radiohalothymidines and methods of their synthesis and use in pet imaging of cancers
TW200738271A (en)	2007-10-16	Methods of making radiolabeled tracers and precursors thereof
WO2007056049A3 (en)	2008-01-31	Molecular profiling of cancer
WO2007033167A3 (en)	2007-10-18	Compositions and methods for detecting and treating cancer
WO2008026051A3 (en)	2008-05-22	68ga-labelling of a free and macromolecule conjugated macrocyclic chelator at ambient temperature
WO2006052975A3 (en)	2007-02-15	Tumor association of mdl-1 and methods
EA200800948A1 (ru)	2010-02-26	Биотиндиаминопроизводные и их конъюгаты с макроциклическими хелатирующими реагентами
ITMC20050119A1 (it)	2007-05-10	SINTESI CHIMICA DI (RAMEDEOSSIGLUCOSIO;[64Cu] TETA-DEOSSIGLUCOSIO), E UTILIZZO DELLO STESSO COME AGENTE PER INDAGINI PET (POSITRON EMISSION TOMOGRAPHY IMAGING) E PER LA RADIOTERAPIA.