NO20074638L - Ny sammensetning - Google Patents
Ny sammensetningInfo
- Publication number
- NO20074638L NO20074638L NO20074638A NO20074638A NO20074638L NO 20074638 L NO20074638 L NO 20074638L NO 20074638 A NO20074638 A NO 20074638A NO 20074638 A NO20074638 A NO 20074638A NO 20074638 L NO20074638 L NO 20074638L
- Authority
- NO
- Norway
- Prior art keywords
- influenza
- relates
- preparation
- antigen
- pandemic outbreak
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000000427 antigen Substances 0.000 abstract 3
- 102000036639 antigens Human genes 0.000 abstract 3
- 108091007433 antigens Proteins 0.000 abstract 3
- 206010022000 influenza Diseases 0.000 abstract 3
- 239000002671 adjuvant Substances 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 229960003971 influenza vaccine Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000007764 o/w emulsion Substances 0.000 abstract 1
- 241000712461 unidentified influenza virus Species 0.000 abstract 1
- 238000002255 vaccination Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
- C07K14/11—Orthomyxoviridae, e.g. influenza virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Foreliggende oppfinnelse angår influensavaksineformuleringer og vaksinasjonsregimer for immunisering mot influensasykdom, anvendelse av dem i medisin, spesielt anvendelse av dem i økning av immunresponser til forskjellige antigener, og fremstillingsmetoder. Spesielt angår oppfinnelsen multivalente influensaimmunogene sammensetninger omfattende et influensaantigen eller antigen fremstilling derav fra minst to influensavirusstammer, der minst én stamme er forbundet med et pandemisk utbrudd eller har potensialet å bli forbundet med et pandemisk utbrudd, i kombinasjon med et olje-i-vann emulsjonadjuvans.
Applications Claiming Priority (14)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0506001A GB0506001D0 (en) | 2005-03-23 | 2005-03-23 | Novel use |
| GB0506000A GB0506000D0 (en) | 2005-03-23 | 2005-03-23 | Novel use |
| GB0505998A GB0505998D0 (en) | 2005-03-23 | 2005-03-23 | Novel compositions |
| GB0505989A GB0505989D0 (en) | 2005-03-23 | 2005-03-23 | Compositions |
| GB0506004A GB0506004D0 (en) | 2005-03-23 | 2005-03-23 | Compositions |
| GB0510589A GB0510589D0 (en) | 2005-05-24 | 2005-05-24 | Novel use |
| GB0510596A GB0510596D0 (en) | 2005-05-24 | 2005-05-24 | Composition |
| GB0510598A GB0510598D0 (en) | 2005-05-24 | 2005-05-24 | Composition |
| GB0510591A GB0510591D0 (en) | 2005-05-24 | 2005-05-24 | Novel use |
| GB0510593A GB0510593D0 (en) | 2005-05-24 | 2005-05-24 | Novel compositions |
| GB0603790A GB0603790D0 (en) | 2006-02-24 | 2006-02-24 | Composition |
| GB0603788A GB0603788D0 (en) | 2006-02-24 | 2006-02-24 | Novel composition |
| GB0603789A GB0603789D0 (en) | 2006-02-24 | 2006-02-24 | Novel use |
| PCT/EP2006/002837 WO2006100110A1 (en) | 2005-03-23 | 2006-03-21 | Novel composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20074638L true NO20074638L (no) | 2007-12-19 |
Family
ID=36441219
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20074635A NO20074635L (no) | 2005-03-23 | 2007-09-12 | Anvendelse av et influensa virus som en olje-i-vann emulsjon adjuvans for a indusere CD4 T-celle og/eller forbedret B-hukommelse celle respons |
| NO20074638A NO20074638L (no) | 2005-03-23 | 2007-09-12 | Ny sammensetning |
| NO20074930A NO20074930L (no) | 2005-03-23 | 2007-09-28 | Blanding |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20074635A NO20074635L (no) | 2005-03-23 | 2007-09-12 | Anvendelse av et influensa virus som en olje-i-vann emulsjon adjuvans for a indusere CD4 T-celle og/eller forbedret B-hukommelse celle respons |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20074930A NO20074930L (no) | 2005-03-23 | 2007-09-28 | Blanding |
Country Status (24)
| Country | Link |
|---|---|
| US (5) | US20080181911A1 (no) |
| EP (4) | EP1863529A1 (no) |
| JP (4) | JP5770414B2 (no) |
| KR (5) | KR20070116651A (no) |
| AR (3) | AR052625A1 (no) |
| AU (3) | AU2006226543B2 (no) |
| CA (3) | CA2601022C (no) |
| CY (1) | CY1117874T1 (no) |
| DK (1) | DK1861120T3 (no) |
| EA (3) | EA011419B1 (no) |
| ES (1) | ES2585810T3 (no) |
| HR (1) | HRP20160816T1 (no) |
| HU (1) | HUE027837T2 (no) |
| IL (3) | IL185901A0 (no) |
| MA (3) | MA29715B1 (no) |
| MX (3) | MX2007011756A (no) |
| NO (3) | NO20074635L (no) |
| NZ (2) | NZ561822A (no) |
| PE (3) | PE20061300A1 (no) |
| PL (1) | PL1861120T3 (no) |
| PT (1) | PT1861120T (no) |
| SI (1) | SI1861120T1 (no) |
| TW (3) | TW200722101A (no) |
| WO (3) | WO2006100109A1 (no) |
Families Citing this family (90)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2457100A (en) * | 1999-02-26 | 2000-09-14 | Chiron S.P.A. | Enhancement of bactericidal activity of neisseria antigens with oligonucleotidescontaining cg motifs |
| GB9923176D0 (en) * | 1999-09-30 | 1999-12-01 | Smithkline Beecham Biolog | Novel composition |
| US20100221284A1 (en) * | 2001-05-30 | 2010-09-02 | Saech-Sisches Serumwerk Dresden | Novel vaccine composition |
| DE10144906B4 (de) | 2001-09-12 | 2013-11-28 | Novartis Vaccines And Diagnostics Gmbh | Verfahren zur großtechnischen Herstellung von Impfstoffen |
| DK1861120T3 (en) | 2005-03-23 | 2016-07-25 | Glaxosmithkline Biologicals Sa | Use of an influenza virus and an oil-in-water emulsion adjuvant to induce CD 4 T cell and / or enhanced B memory cell response |
| WO2007052055A1 (en) * | 2005-11-04 | 2007-05-10 | Novartis Vaccines And Diagnostics Srl | Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture |
| US11707520B2 (en) | 2005-11-03 | 2023-07-25 | Seqirus UK Limited | Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture |
| CA2628424A1 (en) * | 2005-11-04 | 2007-05-10 | Novartis Vaccines And Diagnostics S.R.L. | Adjuvanted influenza vaccines including cytokine-inducing agents |
| WO2007052059A2 (en) | 2005-11-04 | 2007-05-10 | Novartis Vaccines And Diagnostics Srl | Changing th1/th2 balance in split influenza vaccines with adjuvants |
| KR20080069232A (ko) * | 2005-11-04 | 2008-07-25 | 노바티스 백신즈 앤드 다이아그노스틱스 에스.알.엘. | 스플리트 인플루엔자 백신에 대한 보조제로서 유리 수성상계면활성제를 갖는 에멀젼 |
| FR2896162B1 (fr) * | 2006-01-13 | 2008-02-15 | Sanofi Pasteur Sa | Emulsion huile dans eau thermoreversible |
| ES2555544T3 (es) | 2006-03-07 | 2016-01-04 | Vaxinnate Corporation | Composiciones que incluyen hemaglutinina, métodos de preparación y métodos de uso de las mismas |
| WO2007110776A1 (en) * | 2006-03-24 | 2007-10-04 | Novartis Vaccines And Diagnostics Gmbh & Co Kg | Storage of influenza vaccines without refrigeration |
| CN101500603A (zh) * | 2006-06-15 | 2009-08-05 | 诺华有限公司 | 节省佐剂的多剂量流感疫苗接种方案 |
| BRPI0621886B1 (pt) * | 2006-07-17 | 2021-09-21 | Glaxosmithkline Biologicals S.A | Composição de vacina contra influenza monovalente, kit, método para a produção de uma composição de vacina contra influenza para uma situação pandêmica ou uma situação pré- pandêmica, e, usos de um antígeno de vírus da influenza ou preparação antigênica do mesmo e de um adjuvante em emulsão óleo-em-água, de um antígeno de vírus da influenza pandêmica ou preparação antigênica do antígeno de hemaglutinina do vírus da influenza e de um adjuvante em emulsão óleo-em-água e de um antígeno ou preparação antigênica de uma primeira cepa de influenza |
| CA2583555C (en) * | 2006-07-17 | 2020-01-07 | Glaxosmithkline Biologicals S.A. | Influenza vaccine |
| EP2043682B1 (en) * | 2006-07-17 | 2014-04-02 | GlaxoSmithKline Biologicals S.A. | Influenza vaccine |
| EP2433648A3 (en) * | 2006-10-12 | 2012-04-04 | GlaxoSmithKline Biologicals S.A. | Vaccine comprising an oil in water emulsion adjuvant |
| CA2664619C (en) * | 2006-10-12 | 2012-12-11 | Glaxosmithkline Biologicals S.A. | Immunogenic compositions comprising an oil-in-water emulsion adjuvant containing a reduced amount of squalene, tocol and an emulsifying agent |
| GB0622282D0 (en) | 2006-11-08 | 2006-12-20 | Novartis Ag | Quality control methods |
| EP1923070A1 (en) * | 2006-11-15 | 2008-05-21 | Intervet International BV | Vaccine for vaccinating feline against influenza virus |
| JP2011506264A (ja) * | 2006-12-06 | 2011-03-03 | ノバルティス アーゲー | インフルエンザウイルスの4つの株に由来する抗原を含むワクチン |
| EP1938835A1 (en) * | 2006-12-29 | 2008-07-02 | Pevion Biotech AG | Non-specific immunostimulating agents |
| TWI423985B (zh) * | 2007-02-23 | 2014-01-21 | 貝勒研究協會 | 利用dectin-1活化人類抗原呈現細胞之醫療應用 |
| US9452209B2 (en) | 2007-04-20 | 2016-09-27 | Glaxosmithkline Biologicals Sa | Influenza vaccine |
| SG185294A1 (en) * | 2007-10-12 | 2012-11-29 | Csl Ltd | Method of eliciting an immune response against pandemic influenza virus |
| HRP20120433T1 (en) | 2007-10-19 | 2012-07-31 | Novartis@Ag | Meningococcal vaccine formulations |
| GB0810305D0 (en) † | 2008-06-05 | 2008-07-09 | Novartis Ag | Influenza vaccination |
| US8668904B2 (en) * | 2007-12-06 | 2014-03-11 | Glaxosmithkline Biologicals S.A. | Influenza composition |
| TWI376385B (en) * | 2007-12-07 | 2012-11-11 | Nat Health Research Institutes | Production of lipidated proteins in e. coli |
| US8466259B2 (en) * | 2007-12-07 | 2013-06-18 | National Health Research Institutes | Adjuvants |
| JP5518041B2 (ja) * | 2008-03-18 | 2014-06-11 | ノバルティス アーゲー | インフルエンザウイルスワクチン抗原の調製における改良 |
| SG190562A1 (en) | 2008-04-18 | 2013-06-28 | Vaxinnate Corp | Deletion mutants of flagellin and methods of use |
| GB0905570D0 (en) * | 2009-03-31 | 2009-05-13 | Novartis Ag | Combined vaccines |
| EP2310045A1 (en) | 2008-06-25 | 2011-04-20 | Novartis AG | Rapid responses to delayed booster immunisations |
| EA023662B1 (ru) | 2009-02-10 | 2016-06-30 | Новартис Аг | Вакцины против гриппа со сниженным количеством сквалена |
| WO2010092476A1 (en) | 2009-02-10 | 2010-08-19 | Novartis Ag | Influenza vaccine regimens for pandemic-associated strains |
| AU2015203072B2 (en) * | 2009-02-10 | 2017-05-25 | Seqirus UK Limited | Influenza vaccine regimens for pandemic-associated strains |
| US8287880B2 (en) * | 2009-06-02 | 2012-10-16 | National Health Research Institutes | Lipidated vaccine against dengue virus infection |
| US8658176B2 (en) * | 2009-06-22 | 2014-02-25 | National Health Research Institutes | Lipidated tumor-associated antigens and immunotherapeutic compositions |
| EP2289575B1 (de) * | 2009-08-06 | 2017-07-05 | Biotronik VI Patent AG | Medizinisches Implantat enthaltend eine antioxidative Substanz |
| EP2464341B1 (en) * | 2009-08-12 | 2022-07-06 | Sublimity Therapeutics Limited | Immunomodulatory compositions comprising a polymer matrix and an oil phase |
| EP2308506A1 (en) * | 2009-10-02 | 2011-04-13 | Mucosis B.V. | Adjuvanted intranasal vaccine formulations |
| GB0918830D0 (en) | 2009-10-27 | 2009-12-09 | Glaxosmithkline Biolog Niederl | Process |
| GB0919117D0 (en) | 2009-10-30 | 2009-12-16 | Glaxosmithkline Biolog Sa | Process |
| CL2012001399A1 (es) | 2009-12-03 | 2013-03-08 | Novartis Ag | Metodo para fabricar adyuvante para vacuna (emulsion aceite/agua con escualeno, polisorbato 80 y trioleato de sorbitan), que comprende (i) formar primera emulsion en homogenizador desde un contendor a otro para formar segunda emulsion, (ii) y microfluidizar primera emulsion para formar segunda emulsion. |
| ES2477230T3 (es) * | 2009-12-03 | 2014-07-16 | Novartis Ag | Organización cámaras de interacción y de presión de retorno para la microfluidizaci�n |
| SG10201501612RA (en) | 2009-12-03 | 2015-04-29 | Novartis Ag | Hydrophilic filtration during manufacture of vaccine adjuvants |
| DE102009056884B4 (de) | 2009-12-03 | 2021-03-18 | Novartis Ag | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
| DE102009056871A1 (de) * | 2009-12-03 | 2011-06-22 | Novartis AG, 4056 | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
| AU2013202690B2 (en) * | 2009-12-03 | 2016-02-11 | Seqirus UK Limited | Hydrophilic filtration during manufacture of vaccine adjuvants |
| CN102753149B (zh) | 2009-12-03 | 2015-10-14 | 诺华股份有限公司 | 乳液微流化和/或均化期间的组分循环 |
| DE102009056883B4 (de) | 2009-12-03 | 2012-08-16 | Novartis Ag | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
| KR20120107121A (ko) * | 2009-12-22 | 2012-09-28 | 사노피 파스퇴르 리미티드 | 면역원성 조성물 |
| US20130095130A1 (en) * | 2010-01-06 | 2013-04-18 | Vaxinnate Corporation | Methods and Compositions for Providing Protective Immunity in the Elderly |
| WO2011088451A1 (en) * | 2010-01-15 | 2011-07-21 | Novavax, Inc. | Uses of influenza virus-like particles (vlps) for characterization of neuraminidase and hemagglutinin activity |
| RU2527688C2 (ru) * | 2010-02-27 | 2014-09-10 | Общество С Ограниченной Ответственностью "Научно-Производственная Фирма "Материа Медика Холдинг" | Способ лечения инфекционных заболеваний, вызванных вирусом гриппа с типом поверхностого антигена н1n1 и лекарственное средство для лечения инфекционных заболеваний, вызванных вирусом гриппа с типом поверхностного антигена н1n1 |
| GB201009673D0 (en) | 2010-06-10 | 2010-07-21 | Glaxosmithkline Biolog Sa | Novel process |
| GB201009676D0 (en) * | 2010-06-10 | 2010-07-21 | Glaxosmithkline Biolog Sa | Novel process |
| GB201009671D0 (en) | 2010-06-10 | 2010-07-21 | Glaxosmithkline Biolog Sa | Novel process |
| US9821051B1 (en) | 2010-10-28 | 2017-11-21 | Seqirus UK Limited | Reducing hospitalization in elderly influenza vaccine recipients |
| TWI507413B (zh) * | 2010-11-15 | 2015-11-11 | Nat Health Research Institutes | 脂質化多抗原表位疫苗 |
| TW201221642A (en) | 2010-11-15 | 2012-06-01 | Nat Health Research Institutes | Method of producing lipidated polypeptides |
| WO2012116714A1 (en) | 2011-03-02 | 2012-09-07 | Curevac Gmbh | Vaccination in elderly patients |
| HK1209646A1 (en) * | 2012-12-28 | 2016-04-08 | 日本国立感染症研究所 | Nasal influenza vaccine composition |
| JP2016521282A (ja) * | 2013-05-10 | 2016-07-21 | ノバルティス アーゲー | インフルエンザワクチンにおけるナルコレプシーのリスクの回避 |
| CN104436157A (zh) * | 2013-09-23 | 2015-03-25 | 恩金生物有限公司 | 流感疫苗和治疗 |
| US10080792B2 (en) * | 2013-09-23 | 2018-09-25 | Engen Bio, Inc. | Influenza vaccine and therapy |
| ES2927797T3 (es) | 2014-09-26 | 2022-11-11 | Seqirus Uk Ltd | Vacunación de sujetos inmunocomprometidos |
| JP2017528511A (ja) * | 2014-09-26 | 2017-09-28 | セキラス ユーケー リミテッド | 免疫低下された被験体のワクチン接種 |
| WO2019086463A1 (en) | 2017-10-30 | 2019-05-09 | Baxalta GmbH | Environmentally compatible detergents for inactivation of lipid-enveloped viruses |
| WO2019108928A1 (en) * | 2017-11-30 | 2019-06-06 | Ohio State Innovation Foundation | Mucoadhesive nanoparticle entrapped influenza virus vaccine delivery system |
| EP3917567A1 (en) * | 2019-01-30 | 2021-12-08 | GlaxoSmithKline Biologicals SA | Oil/surfactant mixtures for self-emulsification |
| WO2020219719A1 (en) | 2019-04-24 | 2020-10-29 | Icahn School Of Medicine At Mount Sinai | Anti-influenza b virus neuraminidase antibodies and uses thereof |
| CN114867467B (zh) * | 2019-12-20 | 2025-06-20 | 费森尤斯卡比奥地利有限公司 | 用于产生水包油乳剂的方法 |
| RU2741003C1 (ru) * | 2020-03-27 | 2021-01-22 | Евгений Дмитриевич Некрасов | Способ производства четырехвалентной субъединичной вакцины против гриппа без адъювантов |
| EP4171629A1 (en) | 2020-06-29 | 2023-05-03 | GlaxoSmithKline Biologicals S.A. | Adjuvants |
| KR20230054719A (ko) | 2020-08-24 | 2023-04-25 | 사노피 파스퇴르 인크 | Sars-cov-2 감염에 대한 백신 |
| US20240269270A1 (en) | 2020-08-24 | 2024-08-15 | Sanofi Pasteur Inc. | Covid-19 vaccines with tocopherol-containing squalene emulsion adjuvants |
| KR102270165B1 (ko) | 2020-10-22 | 2021-06-28 | 한국화학연구원 | 세정제 조성물 |
| US20240165224A1 (en) | 2021-03-26 | 2024-05-23 | Glaxosmithkline Biologicals Sa | Immunogenic compositions |
| US20250281595A1 (en) | 2021-06-28 | 2025-09-11 | Glaxosmithkline Biologicals Sa | Novel influenza antigens |
| RU2766292C1 (ru) * | 2021-08-05 | 2022-03-14 | Федеральное государственное унитарное предприятие "Санкт-Петербургский научно-исследовательский институт вакцин и сывороток и предприятие по производству бактерийных препаратов" Федерального медико-биологического агентства (ФГУП СПбНИИВС ФМБА России) | Состав вакцины против covid-19 |
| WO2023020994A1 (en) | 2021-08-16 | 2023-02-23 | Glaxosmithkline Biologicals Sa | Novel methods |
| WO2023020993A1 (en) | 2021-08-16 | 2023-02-23 | Glaxosmithkline Biologicals Sa | Novel methods |
| WO2023020992A1 (en) | 2021-08-16 | 2023-02-23 | Glaxosmithkline Biologicals Sa | Novel methods |
| WO2023061993A1 (en) | 2021-10-13 | 2023-04-20 | Glaxosmithkline Biologicals Sa | Polypeptides |
| GB202219228D0 (en) | 2022-12-20 | 2023-02-01 | Glaxosmithkline Biologicals Sa | Novel influenza antigens |
| WO2025019631A1 (en) | 2023-07-19 | 2025-01-23 | Icahn School Of Medicine At Mount Sinai | Immunogenic compositions containing inactivated influenza a virus and cpg oligonucleotide adjuvant and uses thereof |
| EP4670733A1 (en) | 2024-06-27 | 2025-12-31 | Sanofi | METHODS FOR PREPARING VIRAL PROTEINS AND THEIR USES |
Family Cites Families (116)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3095974A (en) * | 1961-10-27 | 1963-07-02 | Anthony R Perini | Collapsible book rack |
| US4047869A (en) * | 1973-02-23 | 1977-09-13 | Mulvany Jr R F | Apparatus for forming plastic articles |
| FR2333610A1 (fr) * | 1975-12-03 | 1977-07-01 | Zhdanovsky Z Tyazhelogo Mash | Bande-electrode a ame en poudre pour rechargement a l'aide d'un alliage resistant a l'usure |
| US4270537A (en) | 1979-11-19 | 1981-06-02 | Romaine Richard A | Automatic hypodermic syringe |
| DD155875A1 (de) | 1980-12-31 | 1982-07-14 | Willy Nordheim | Verfahren zur herstellung eines ballaststoffarmen inaktivierten influenzaimpfstoffes |
| US4436727A (en) * | 1982-05-26 | 1984-03-13 | Ribi Immunochem Research, Inc. | Refined detoxified endotoxin product |
| US4866034A (en) * | 1982-05-26 | 1989-09-12 | Ribi Immunochem Research Inc. | Refined detoxified endotoxin |
| DD211444A3 (de) | 1982-08-19 | 1984-07-11 | Saechsisches Serumwerk | Verfahren zur herstellung von influenza-impfstoffen |
| GB8300467D0 (en) | 1983-01-08 | 1983-02-09 | Wellcome Found | Equine influenza |
| US4596556A (en) | 1985-03-25 | 1986-06-24 | Bioject, Inc. | Hypodermic injection apparatus |
| DD300833A7 (de) | 1985-10-28 | 1992-08-13 | Saechsische Landesgewerbefoerd | Verfahren zur herstellung von inaktivierten influenza-vollvirusimpfstoffen |
| CA1283827C (en) | 1986-12-18 | 1991-05-07 | Giorgio Cirelli | Appliance for injection of liquid formulations |
| GB8704027D0 (en) | 1987-02-20 | 1987-03-25 | Owen Mumford Ltd | Syringe needle combination |
| WO1988009797A1 (en) | 1987-06-05 | 1988-12-15 | The United States Of America, As Represented By Th | Autocrine motility factors in cancer diagnosis and management |
| US4940460A (en) | 1987-06-19 | 1990-07-10 | Bioject, Inc. | Patient-fillable and non-invasive hypodermic injection device assembly |
| US4790824A (en) | 1987-06-19 | 1988-12-13 | Bioject, Inc. | Non-invasive hypodermic injection device |
| US4941880A (en) | 1987-06-19 | 1990-07-17 | Bioject, Inc. | Pre-filled ampule and non-invasive hypodermic injection device assembly |
| DE3734306A1 (de) | 1987-10-10 | 1989-04-27 | Pfeiffer Erich Gmbh & Co Kg | Austragvorrichtung fuer fliessfaehige medien |
| US5376369A (en) * | 1987-11-03 | 1994-12-27 | Syntex (U.S.A.) Inc. | Vaccine adjuvant |
| US5339163A (en) | 1988-03-16 | 1994-08-16 | Canon Kabushiki Kaisha | Automatic exposure control device using plural image plane detection areas |
| US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| GB8821049D0 (en) | 1988-09-08 | 1988-10-05 | Health Lab Service Board | Method & composition for treatment & prevention of viral infections |
| FR2638359A1 (fr) | 1988-11-03 | 1990-05-04 | Tino Dalto | Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau |
| ATE115862T1 (de) * | 1989-02-04 | 1995-01-15 | Akzo Nobel Nv | Tocole als impfstoffadjuvans. |
| US5092235A (en) | 1989-05-24 | 1992-03-03 | Tektronix, Inc. | Pressure fixing and developing apparatus |
| WO1990014837A1 (en) | 1989-05-25 | 1990-12-13 | Chiron Corporation | Adjuvant formulation comprising a submicron oil droplet emulsion |
| US5064413A (en) | 1989-11-09 | 1991-11-12 | Bioject, Inc. | Needleless hypodermic injection device |
| US5312335A (en) | 1989-11-09 | 1994-05-17 | Bioject Inc. | Needleless hypodermic injection device |
| DE4005528C2 (de) | 1990-02-22 | 1998-01-15 | Pfeiffer Erich Gmbh & Co Kg | Austragvorrichtung für Medien |
| US5969109A (en) * | 1990-02-28 | 1999-10-19 | Bona; Constantin | Chimeric antibodies comprising antigen binding sites and B and T cell epitopes |
| WO1991013261A1 (fr) | 1990-03-02 | 1991-09-05 | Experimentalny Nauchno-Issledovatelsky Institut Metallorezhuschikh Stankov | Systeme numerique d'entrainement asservi |
| US5149531A (en) * | 1990-06-27 | 1992-09-22 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Method of using cold-adapted live influenza virus vaccine as an antiviral agent against influenza |
| US5190521A (en) | 1990-08-22 | 1993-03-02 | Tecnol Medical Products, Inc. | Apparatus and method for raising a skin wheal and anesthetizing skin |
| US5527288A (en) | 1990-12-13 | 1996-06-18 | Elan Medical Technologies Limited | Intradermal drug delivery device and method for intradermal delivery of drugs |
| GB9105992D0 (en) | 1991-03-21 | 1991-05-08 | Smithkline Beecham Biolog | Vaccine |
| GB9118204D0 (en) | 1991-08-23 | 1991-10-09 | Weston Terence E | Needle-less injector |
| SE9102652D0 (sv) | 1991-09-13 | 1991-09-13 | Kabi Pharmacia Ab | Injection needle arrangement |
| US5328483A (en) | 1992-02-27 | 1994-07-12 | Jacoby Richard M | Intradermal injection device with medication and needle guard |
| MY111880A (en) | 1992-03-27 | 2001-02-28 | Smithkline Beecham Biologicals S A | Hepatitis vaccines containing 3-0 deacylated monophosphoryl lipid a |
| US5383851A (en) | 1992-07-24 | 1995-01-24 | Bioject Inc. | Needleless hypodermic injection device |
| US5569189A (en) | 1992-09-28 | 1996-10-29 | Equidyne Systems, Inc. | hypodermic jet injector |
| US5334144A (en) | 1992-10-30 | 1994-08-02 | Becton, Dickinson And Company | Single use disposable needleless injector |
| CA2156525A1 (en) | 1993-02-19 | 1994-09-01 | Susan Dillon | Influenza vaccine compositions containing 3-o-deacylated monophosphoryl lipid a |
| CN1124013A (zh) * | 1993-02-19 | 1996-06-05 | 史密丝克莱恩比彻姆公司 | 含3-邻位-脱酰基的单磷酰基脂质a的流感疫苗组合物 |
| KR100310510B1 (ko) | 1993-03-23 | 2002-07-04 | 장 스테판느 | 3-0-탈아세틸화모노포스포릴지질a를함유하는백신조성물 |
| US5762939A (en) * | 1993-09-13 | 1998-06-09 | Mg-Pmc, Llc | Method for producing influenza hemagglutinin multivalent vaccines using baculovirus |
| WO1995011700A1 (en) | 1993-10-29 | 1995-05-04 | Pharmos Corp. | Submicron emulsions as vaccine adjuvants |
| PT729473E (pt) | 1993-11-17 | 2001-02-28 | Deutsche Om Arzneimittel Gmbh | Dissacaridos de glucosamina metodo para a sua preparacao composicao farmaceutica contendo os mesmos e sua utilizacao |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| JP3836874B2 (ja) | 1994-02-24 | 2006-10-25 | ノババックス インコーポレイテッド | 免疫アジュバントとして少ラメラ脂質小胞を含むワクチン |
| WO1995024176A1 (en) | 1994-03-07 | 1995-09-14 | Bioject, Inc. | Ampule filling device |
| US5466220A (en) | 1994-03-08 | 1995-11-14 | Bioject, Inc. | Drug vial mixing and transfer device |
| WO1995026204A1 (en) | 1994-03-25 | 1995-10-05 | Isis Pharmaceuticals, Inc. | Immune stimulation by phosphorothioate oligonucleotide analogs |
| US5599302A (en) | 1995-01-09 | 1997-02-04 | Medi-Ject Corporation | Medical injection system and method, gas spring thereof and launching device using gas spring |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| US5730723A (en) | 1995-10-10 | 1998-03-24 | Visionary Medical Products Corporation, Inc. | Gas pressured needle-less injection device and method |
| US5893397A (en) | 1996-01-12 | 1999-04-13 | Bioject Inc. | Medication vial/syringe liquid-transfer apparatus |
| GB9607549D0 (en) | 1996-04-11 | 1996-06-12 | Weston Medical Ltd | Spring-powered dispensing device |
| US5916879A (en) | 1996-11-12 | 1999-06-29 | St. Jude Children's Research Hospital | DNA transcription unit vaccines that protect against avian influenza viruses and methods of use thereof |
| TW570803B (en) | 1997-04-09 | 2004-01-11 | Duphar Int Res | Influenza vaccine |
| US5993412A (en) | 1997-05-19 | 1999-11-30 | Bioject, Inc. | Injection apparatus |
| GB9711990D0 (en) | 1997-06-11 | 1997-08-06 | Smithkline Beecham Biolog | Vaccine |
| EP1279401B1 (en) * | 1997-09-05 | 2008-01-09 | GlaxoSmithKline Biologicals S.A. | Oil in water emulsions containing saponins |
| GB9718901D0 (en) | 1997-09-05 | 1997-11-12 | Smithkline Beecham Biolog | Vaccine |
| IT1298087B1 (it) | 1998-01-08 | 1999-12-20 | Fiderm S R L | Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni |
| TR200002608T2 (tr) * | 1998-03-09 | 2000-11-21 | Smithkline Beecham Biologicals S.A | Kombine aşı kompozisyonları |
| US6838269B1 (en) * | 1998-04-15 | 2005-01-04 | Genencor International, Inc. | Proteins producing an altered immunogenic response and methods of making and using the same |
| CA2330610A1 (en) | 1998-05-07 | 1999-11-11 | Corixa Corporation | Adjuvant composition and methods for its use |
| EP1089913A1 (fr) | 1998-06-08 | 2001-04-11 | SCA Emballage France | Emballage a remise a plat rapide |
| SK287073B6 (sk) | 1998-06-30 | 2009-11-05 | Om Pharma | N-Acyldipeptidový derivát, spôsob jeho prípravy a farmaceutický prostriedok, ktorý ho obsahuje |
| AT408615B (de) | 1998-09-15 | 2002-01-25 | Immuno Ag | Neue influenzavirus-impfstoffzusammensetzung |
| US20040006242A1 (en) | 1999-02-01 | 2004-01-08 | Hawkins Lynn D. | Immunomodulatory compounds and method of use thereof |
| US6551600B2 (en) | 1999-02-01 | 2003-04-22 | Eisai Co., Ltd. | Immunological adjuvant compounds compositions and methods of use thereof |
| AT407958B (de) | 1999-02-11 | 2001-07-25 | Immuno Ag | Inaktivierte influenza-virus-vakzine zur nasalen oder oralen applikation |
| WO2000050006A2 (en) | 1999-02-26 | 2000-08-31 | Chiron Corporation | Microemulsions with adsorbed macromoelecules and microparticles |
| FR2796290B1 (fr) | 1999-07-16 | 2001-09-14 | Cross Site Technologies | Seringue sans aiguille fonctionnant avec un generateur d'onde de choc a travers une paroi |
| FR2796289B1 (fr) | 1999-07-16 | 2001-08-10 | Cross Site Technologies | Seringue sans aiguille avec injecteur a elements superposes |
| FR2796291B1 (fr) | 1999-07-16 | 2001-09-21 | Cross Site Technologies | Seringue sans aiguille munie d'un systeme de declenchement piezo-electrique |
| GB9921147D0 (en) * | 1999-09-07 | 1999-11-10 | Smithkline Beecham Biolog | Novel composition |
| GB9921146D0 (en) * | 1999-09-07 | 1999-11-10 | Smithkline Beecham Biolog | Novel composition |
| GB9923176D0 (en) * | 1999-09-30 | 1999-12-01 | Smithkline Beecham Biolog | Novel composition |
| US6494865B1 (en) | 1999-10-14 | 2002-12-17 | Becton Dickinson And Company | Intradermal delivery device including a needle assembly |
| FR2800619B1 (fr) | 1999-11-05 | 2002-02-08 | Cross Site Technologies | Seringue sans aiguille avec un moyen de poussee temporairement retenu |
| FR2802103B1 (fr) | 1999-12-08 | 2003-10-03 | Poudres & Explosifs Ste Nale | Seringue sans aiguille fonctionnant avec entrainement du principe actif par effet tube a choc |
| FR2802102B1 (fr) | 1999-12-08 | 2002-07-12 | Poudres & Explosifs Ste Nale | Seringue sans aiguille munie d'un tube d'ejection a section constante |
| AU1581400A (en) | 1999-12-22 | 2001-07-03 | Om Pharma | Acyl pseudopeptides bearing a functionalised auxiliary spacer |
| FR2802820B1 (fr) | 1999-12-27 | 2002-10-18 | Poudres & Explosifs Ste Nale | Seringue sans aiguille fonctionnant par effet tube a choc, avec maintien prealable du principe actif sur le cote |
| JP2003529559A (ja) | 2000-01-31 | 2003-10-07 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 新規用途 |
| FR2804329B1 (fr) | 2000-02-02 | 2002-12-13 | Poudres & Explosifs Ste Nale | Seringue sans aiguille munie d'un opercule contenant le principe actif |
| FR2804869B1 (fr) | 2000-02-11 | 2002-05-17 | Poudres & Explosifs Ste Nale | Seringue sans aiguille pour l'injection d'un liquide contenu dans une ampoule pre-remplie |
| FR2805749B1 (fr) | 2000-03-01 | 2002-05-17 | Poudres & Explosifs Ste Nale | Seringue sans aiguille a deux niveaux de vitesse d'injection |
| FR2807946B1 (fr) | 2000-04-19 | 2002-06-07 | Poudres & Explosifs Ste Nale | Seringue sans aiguille fonctionnant avec un chargement pyrotechnique bicomposition |
| FR2809626B1 (fr) | 2000-05-30 | 2003-03-07 | Poudres & Explosifs Ste Nale | Seringue sans aiguille avec membrane d'isolation d'un ejecteur multiconduit |
| FR2810554B1 (fr) | 2000-06-22 | 2003-05-16 | Poudres & Explosifs Ste Nale | Seringue sans aiguille munie d'un reservoir modulable |
| FR2812202B1 (fr) | 2000-07-28 | 2002-09-13 | Poudres & Explosifs Ste Nale | Seringue sans aiguille fonctionnant par mise en compression du reservoir contenant le principe actif liquide |
| GB0025577D0 (en) | 2000-10-18 | 2000-12-06 | Smithkline Beecham Biolog | Vaccine |
| FR2815544B1 (fr) | 2000-10-23 | 2003-02-14 | Poudres & Explosifs Ste Nale | Seringue sans aiguille securisee a architecture compacte |
| EP1201250A1 (en) | 2000-10-25 | 2002-05-02 | SMITHKLINE BEECHAM BIOLOGICALS s.a. | Immunogenic compositions comprising liver stage malarial antigens |
| EP1361890B1 (en) | 2001-02-23 | 2011-03-30 | GlaxoSmithKline Biologicals s.a. | Influenza vaccine formulations for intradermal delivery |
| MY134424A (en) * | 2001-05-30 | 2007-12-31 | Saechsisches Serumwerk | Stable influenza virus preparations with low or no amount of thiomersal |
| US7361352B2 (en) * | 2001-08-15 | 2008-04-22 | Acambis, Inc. | Influenza immunogen and vaccine |
| US6861410B1 (en) | 2002-03-21 | 2005-03-01 | Chiron Corporation | Immunological adjuvant compositions |
| AU2003224819A1 (en) * | 2002-04-01 | 2003-10-20 | Euro-Celtique S.A. | Epitope constructs comprising antigen presenting cell targeting mechanisms |
| CA2514667C (en) | 2003-01-30 | 2013-01-08 | Chiron Corporation | Adjuvanted influenza vaccine |
| US20080254065A1 (en) * | 2004-03-09 | 2008-10-16 | Chiron Corporation | Influenza Virus Vaccines |
| US20090028903A1 (en) * | 2005-03-23 | 2009-01-29 | Glaxosmithkline Biologicals, S.A. | Novel use |
| DK1861120T3 (en) | 2005-03-23 | 2016-07-25 | Glaxosmithkline Biologicals Sa | Use of an influenza virus and an oil-in-water emulsion adjuvant to induce CD 4 T cell and / or enhanced B memory cell response |
| AR054822A1 (es) | 2005-07-07 | 2007-07-18 | Sanofi Pasteur | Emulsion inmuno adyuvante |
| NZ594482A (en) | 2005-11-04 | 2012-11-30 | Novartis Vaccines & Diagnostic | Influenza vaccines with reduced amount of oil-in-water emulsion as adjuvant |
| FR2896162B1 (fr) | 2006-01-13 | 2008-02-15 | Sanofi Pasteur Sa | Emulsion huile dans eau thermoreversible |
| WO2007130330A2 (en) | 2006-05-01 | 2007-11-15 | Technovax, Inc. | Polyvalent influenza virus-like particle (vlp) compositions |
| EP2043682B1 (en) | 2006-07-17 | 2014-04-02 | GlaxoSmithKline Biologicals S.A. | Influenza vaccine |
| BRPI0621886B1 (pt) * | 2006-07-17 | 2021-09-21 | Glaxosmithkline Biologicals S.A | Composição de vacina contra influenza monovalente, kit, método para a produção de uma composição de vacina contra influenza para uma situação pandêmica ou uma situação pré- pandêmica, e, usos de um antígeno de vírus da influenza ou preparação antigênica do mesmo e de um adjuvante em emulsão óleo-em-água, de um antígeno de vírus da influenza pandêmica ou preparação antigênica do antígeno de hemaglutinina do vírus da influenza e de um adjuvante em emulsão óleo-em-água e de um antígeno ou preparação antigênica de uma primeira cepa de influenza |
| CA2664619C (en) * | 2006-10-12 | 2012-12-11 | Glaxosmithkline Biologicals S.A. | Immunogenic compositions comprising an oil-in-water emulsion adjuvant containing a reduced amount of squalene, tocol and an emulsifying agent |
| US9452209B2 (en) * | 2007-04-20 | 2016-09-27 | Glaxosmithkline Biologicals Sa | Influenza vaccine |
| US8668904B2 (en) * | 2007-12-06 | 2014-03-11 | Glaxosmithkline Biologicals S.A. | Influenza composition |
-
2006
- 2006-03-21 DK DK06723805.5T patent/DK1861120T3/en active
- 2006-03-21 KR KR1020077024383A patent/KR20070116651A/ko not_active Withdrawn
- 2006-03-21 NZ NZ561822A patent/NZ561822A/en not_active IP Right Cessation
- 2006-03-21 ES ES06723805.5T patent/ES2585810T3/es not_active Expired - Lifetime
- 2006-03-21 US US11/909,351 patent/US20080181911A1/en not_active Abandoned
- 2006-03-21 TW TW095109708A patent/TW200722101A/zh unknown
- 2006-03-21 PE PE2006000311A patent/PE20061300A1/es not_active Application Discontinuation
- 2006-03-21 EA EA200701786A patent/EA011419B1/ru not_active IP Right Cessation
- 2006-03-21 EP EP06723806A patent/EP1863529A1/en not_active Withdrawn
- 2006-03-21 EP EP06723807A patent/EP1861122A1/en not_active Withdrawn
- 2006-03-21 AR ARP060101108A patent/AR052625A1/es unknown
- 2006-03-21 TW TW095109709A patent/TW200700079A/zh unknown
- 2006-03-21 KR KR1020077024388A patent/KR20070116652A/ko not_active Ceased
- 2006-03-21 EP EP06723805.5A patent/EP1861120B1/en not_active Expired - Lifetime
- 2006-03-21 JP JP2008502345A patent/JP5770414B2/ja not_active Expired - Fee Related
- 2006-03-21 MX MX2007011756A patent/MX2007011756A/es active IP Right Grant
- 2006-03-21 MX MX2007011748A patent/MX2007011748A/es not_active Application Discontinuation
- 2006-03-21 CA CA2601022A patent/CA2601022C/en not_active Expired - Lifetime
- 2006-03-21 KR KR1020167014235A patent/KR20160064249A/ko not_active Ceased
- 2006-03-21 HU HUE06723805A patent/HUE027837T2/en unknown
- 2006-03-21 SI SI200632082A patent/SI1861120T1/sl unknown
- 2006-03-21 EA EA200701785A patent/EA011393B1/ru not_active IP Right Cessation
- 2006-03-21 AR ARP060101106A patent/AR053833A1/es not_active Application Discontinuation
- 2006-03-21 WO PCT/EP2006/002836 patent/WO2006100109A1/en not_active Ceased
- 2006-03-21 AR ARP060101107A patent/AR054020A1/es not_active Application Discontinuation
- 2006-03-21 KR KR1020077024380A patent/KR20070116650A/ko not_active Ceased
- 2006-03-21 KR KR1020137034497A patent/KR101916787B1/ko not_active Expired - Fee Related
- 2006-03-21 PL PL06723805.5T patent/PL1861120T3/pl unknown
- 2006-03-21 MX MX2007011775A patent/MX2007011775A/es not_active Application Discontinuation
- 2006-03-21 US US11/909,414 patent/US20090081253A1/en not_active Abandoned
- 2006-03-21 EA EA200701787A patent/EA200701787A1/ru unknown
- 2006-03-21 PT PT67238055T patent/PT1861120T/pt unknown
- 2006-03-21 CA CA002602456A patent/CA2602456A1/en not_active Abandoned
- 2006-03-21 JP JP2008502346A patent/JP2008534467A/ja active Pending
- 2006-03-21 CA CA2603180A patent/CA2603180C/en not_active Expired - Lifetime
- 2006-03-21 WO PCT/EP2006/002837 patent/WO2006100110A1/en not_active Ceased
- 2006-03-21 TW TW095109703A patent/TW200700078A/zh unknown
- 2006-03-21 EP EP11173265A patent/EP2397153A1/en not_active Withdrawn
- 2006-03-21 WO PCT/EP2006/002838 patent/WO2006100111A1/en not_active Ceased
- 2006-03-21 JP JP2008502344A patent/JP5869744B2/ja not_active Expired - Fee Related
- 2006-03-21 AU AU2006226543A patent/AU2006226543B2/en not_active Ceased
- 2006-03-21 US US11/909,388 patent/US20080171063A1/en not_active Abandoned
- 2006-03-21 HR HRP20160816TT patent/HRP20160816T1/hr unknown
- 2006-03-21 AU AU2006226459A patent/AU2006226459A1/en not_active Abandoned
- 2006-03-21 PE PE2006000312A patent/PE20061428A1/es not_active Application Discontinuation
- 2006-03-21 NZ NZ561823A patent/NZ561823A/en not_active IP Right Cessation
- 2006-03-21 AU AU2006226458A patent/AU2006226458B2/en not_active Ceased
- 2006-03-23 PE PE2006000334A patent/PE20061387A1/es not_active Application Discontinuation
-
2007
- 2007-09-11 IL IL185901A patent/IL185901A0/en unknown
- 2007-09-11 IL IL185906A patent/IL185906A0/en unknown
- 2007-09-11 IL IL185897A patent/IL185897A/en active IP Right Grant
- 2007-09-12 NO NO20074635A patent/NO20074635L/no not_active Application Discontinuation
- 2007-09-12 NO NO20074638A patent/NO20074638L/no not_active Application Discontinuation
- 2007-09-24 MA MA30240A patent/MA29715B1/fr unknown
- 2007-09-24 MA MA30238A patent/MA30298B1/fr unknown
- 2007-09-24 MA MA30241A patent/MA29342B1/fr unknown
- 2007-09-28 NO NO20074930A patent/NO20074930L/no not_active Application Discontinuation
-
2011
- 2011-04-28 US US13/096,180 patent/US20110287054A1/en not_active Abandoned
-
2014
- 2014-01-31 JP JP2014016254A patent/JP2014129359A/ja active Pending
- 2014-08-21 US US14/465,055 patent/US9730999B2/en not_active Expired - Fee Related
-
2016
- 2016-08-05 CY CY20161100772T patent/CY1117874T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TW200722101A (en) | Novel composition | |
| Honda-Okubo et al. | Advax™, a polysaccharide adjuvant derived from delta inulin, provides improved influenza vaccine protection through broad-based enhancement of adaptive immune responses | |
| NO20090062L (no) | Influensavaksine | |
| Maroof et al. | Intranasal vaccination promotes detrimental Th17-mediated immunity against influenza infection | |
| MX2010012999A (es) | Vacuna de vesícula de membrana externa nativa multivalente del meningococo, método para su fabricación y uso. | |
| JP2011504486A5 (no) | ||
| NO20082472L (no) | Vaksinesammensetninger omfattende en saponin adjuvant | |
| BR112013005427A2 (pt) | composição imunogênica, vacina, método para tratamento ou prevenção de doença, e para preparar a composição imunogênica ou vacina, uso da vacina,e, composição farmacêutica. | |
| BR112013009649A2 (pt) | composição imunogênica, métodos para provocar uma resposta imune protetora em um paciente humano e para fornecer proteção imune em seres humanos contra doença, e, uso de uma composição | |
| Romeli et al. | Multi-epitope peptide-based and vaccinia-based universal influenza vaccine candidates subjected to clinical trials | |
| Khalil et al. | A tetravalent alphavirus-vector based dengue vaccine provides effective immunity in an early life mouse model | |
| Lowell et al. | Back to the future: Immunization with M-001 prior to trivalent influenza vaccine in 2011/12 enhanced protective immune responses against 2014/15 epidemic strain | |
| Morçӧl et al. | Calcium phosphate nanoparticle (CaPNP) for dose-sparing of inactivated whole virus pandemic influenza A (H1N1) 2009 vaccine in mice | |
| Garg et al. | Alum adjuvanted rabies DNA vaccine confers 80% protection against lethal 50 LD50 rabies challenge virus standard strain | |
| BRPI0621886A8 (pt) | composição de vacina contra influenza monovalente, kit, método para a produção de uma composição de vacina contra influenza para uma situação pandêmica ou uma situação pré-pandêmica, e, usos de um antígeno de vírus da influenza ou preparação antigênica do mesmo e de um adjuvante em emulsão óleo-em-água, de um antígeno de vírus da influenza pandêmica ou preparação antigênica do antígeno de hemaglutinina do vírus da influenza, de um vírus da influenza pandêmica ou preparação antigênica do mesmo, e de um adjuvante em emulsão óleo-em-água e de um antígeno ou preparação antigênica de uma primeira cepa de influenza | |
| Jones et al. | A nasal Proteosome™ influenza vaccine containing baculovirus-derived hemagglutinin induces protective mucosal and systemic immunity | |
| BR112014023283A8 (pt) | Composição imunogênica, segunda composição imunogênica, e, método para prevenção e/ou tratamento contra doença influenza | |
| Jiang et al. | Antigen sparing and enhanced protection using a novel rOv-ASP-1 adjuvant in aqueous formulation with influenza vaccines | |
| Cox et al. | Matrix-M™ adjuvation broadens protection induced by seasonal trivalent virosomal influenza vaccine | |
| Rudenko et al. | Current strategies for the prevention of influenza by the Russian cold-adapted live influenza vaccine among different populations | |
| Ng et al. | Lipopeptide vaccines illustrate the potential role of subtype‐crossreactive T cells in the control of highly virulent influenza | |
| Van Buynder | Enhancing influenza vaccination in older people | |
| Young et al. | Immunologic characterization of a novel inactivated nasal mumps virus vaccine adjuvanted with Protollin | |
| SG160386A1 (en) | Novel composition | |
| Patil et al. | Development of autogenous vaccine for effective control of Infectious coryza in chicken |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |