NO20074638L - Ny sammensetning - Google Patents
Ny sammensetningInfo
- Publication number
- NO20074638L NO20074638L NO20074638A NO20074638A NO20074638L NO 20074638 L NO20074638 L NO 20074638L NO 20074638 A NO20074638 A NO 20074638A NO 20074638 A NO20074638 A NO 20074638A NO 20074638 L NO20074638 L NO 20074638L
- Authority
- NO
- Norway
- Prior art keywords
- influenza
- relates
- preparation
- antigen
- pandemic outbreak
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000000427 antigen Substances 0.000 abstract 3
- 102000036639 antigens Human genes 0.000 abstract 3
- 108091007433 antigens Proteins 0.000 abstract 3
- 206010022000 influenza Diseases 0.000 abstract 3
- 239000002671 adjuvant Substances 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 229960003971 influenza vaccine Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000007764 o/w emulsion Substances 0.000 abstract 1
- 241000712461 unidentified influenza virus Species 0.000 abstract 1
- 238000002255 vaccination Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
- C07K14/11—Orthomyxoviridae, e.g. influenza virus
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Foreliggende oppfinnelse angår influensavaksineformuleringer og vaksinasjonsregimer for immunisering mot influensasykdom, anvendelse av dem i medisin, spesielt anvendelse av dem i økning av immunresponser til forskjellige antigener, og fremstillingsmetoder. Spesielt angår oppfinnelsen multivalente influensaimmunogene sammensetninger omfattende et influensaantigen eller antigen fremstilling derav fra minst to influensavirusstammer, der minst én stamme er forbundet med et pandemisk utbrudd eller har potensialet å bli forbundet med et pandemisk utbrudd, i kombinasjon med et olje-i-vann emulsjonadjuvans.
Applications Claiming Priority (14)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0505998A GB0505998D0 (en) | 2005-03-23 | 2005-03-23 | Novel compositions |
| GB0506000A GB0506000D0 (en) | 2005-03-23 | 2005-03-23 | Novel use |
| GB0506001A GB0506001D0 (en) | 2005-03-23 | 2005-03-23 | Novel use |
| GB0506004A GB0506004D0 (en) | 2005-03-23 | 2005-03-23 | Compositions |
| GB0505989A GB0505989D0 (en) | 2005-03-23 | 2005-03-23 | Compositions |
| GB0510598A GB0510598D0 (en) | 2005-05-24 | 2005-05-24 | Composition |
| GB0510596A GB0510596D0 (en) | 2005-05-24 | 2005-05-24 | Composition |
| GB0510593A GB0510593D0 (en) | 2005-05-24 | 2005-05-24 | Novel compositions |
| GB0510591A GB0510591D0 (en) | 2005-05-24 | 2005-05-24 | Novel use |
| GB0510589A GB0510589D0 (en) | 2005-05-24 | 2005-05-24 | Novel use |
| GB0603789A GB0603789D0 (en) | 2006-02-24 | 2006-02-24 | Novel use |
| GB0603788A GB0603788D0 (en) | 2006-02-24 | 2006-02-24 | Novel composition |
| GB0603790A GB0603790D0 (en) | 2006-02-24 | 2006-02-24 | Composition |
| PCT/EP2006/002837 WO2006100110A1 (en) | 2005-03-23 | 2006-03-21 | Novel composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20074638L true NO20074638L (no) | 2007-12-19 |
Family
ID=36441219
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20074635A NO20074635L (no) | 2005-03-23 | 2007-09-12 | Anvendelse av et influensa virus som en olje-i-vann emulsjon adjuvans for a indusere CD4 T-celle og/eller forbedret B-hukommelse celle respons |
| NO20074638A NO20074638L (no) | 2005-03-23 | 2007-09-12 | Ny sammensetning |
| NO20074930A NO20074930L (no) | 2005-03-23 | 2007-09-28 | Blanding |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20074635A NO20074635L (no) | 2005-03-23 | 2007-09-12 | Anvendelse av et influensa virus som en olje-i-vann emulsjon adjuvans for a indusere CD4 T-celle og/eller forbedret B-hukommelse celle respons |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20074930A NO20074930L (no) | 2005-03-23 | 2007-09-28 | Blanding |
Country Status (24)
| Country | Link |
|---|---|
| US (5) | US20080181911A1 (no) |
| EP (4) | EP1863529A1 (no) |
| JP (4) | JP5869744B2 (no) |
| KR (5) | KR20070116650A (no) |
| AR (3) | AR054020A1 (no) |
| AU (3) | AU2006226459A1 (no) |
| CA (3) | CA2601022C (no) |
| CY (1) | CY1117874T1 (no) |
| DK (1) | DK1861120T3 (no) |
| EA (3) | EA200701787A1 (no) |
| ES (1) | ES2585810T3 (no) |
| HR (1) | HRP20160816T1 (no) |
| HU (1) | HUE027837T2 (no) |
| IL (3) | IL185897A (no) |
| MA (3) | MA29715B1 (no) |
| MX (3) | MX2007011775A (no) |
| NO (3) | NO20074635L (no) |
| NZ (2) | NZ561823A (no) |
| PE (3) | PE20061428A1 (no) |
| PL (1) | PL1861120T3 (no) |
| PT (1) | PT1861120T (no) |
| SI (1) | SI1861120T1 (no) |
| TW (3) | TW200700079A (no) |
| WO (3) | WO2006100111A1 (no) |
Families Citing this family (90)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4812942B2 (ja) * | 1999-02-26 | 2011-11-09 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | CGモチーフを含むオリゴヌクレオチドを用いるNeisseria抗原殺菌活性の増強 |
| GB9923176D0 (en) * | 1999-09-30 | 1999-12-01 | Smithkline Beecham Biolog | Novel composition |
| US20100221284A1 (en) * | 2001-05-30 | 2010-09-02 | Saech-Sisches Serumwerk Dresden | Novel vaccine composition |
| DE10144906B4 (de) | 2001-09-12 | 2013-11-28 | Novartis Vaccines And Diagnostics Gmbh | Verfahren zur großtechnischen Herstellung von Impfstoffen |
| PT1861120T (pt) * | 2005-03-23 | 2016-08-18 | Glaxosmithkline Biologicals Sa | Utilização de um vírus influenza e de um adjuvante de emulsão óleo-em-água para induzir células t cd4 e/ou melhorar a resposta de células b de memória |
| US11707520B2 (en) | 2005-11-03 | 2023-07-25 | Seqirus UK Limited | Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture |
| WO2007052061A2 (en) * | 2005-11-04 | 2007-05-10 | Novartis Vaccines And Diagnostics Srl | Emulsions with free aqueous-phase surfactant as adjuvants for split influenza vaccines |
| WO2007052059A2 (en) * | 2005-11-04 | 2007-05-10 | Novartis Vaccines And Diagnostics Srl | Changing th1/th2 balance in split influenza vaccines with adjuvants |
| ES2420829T3 (es) * | 2005-11-04 | 2013-08-27 | Novartis Vaccines And Diagnostics S.R.L. | Vacunas adyuvantadas con antígeno de no virión preparadas a partir de virus de la gripe cultivados en cultivo celular |
| EP1951298A1 (en) * | 2005-11-04 | 2008-08-06 | Novartis Vaccines and Diagnostics S.r.l. | Adjuvanted influenza vaccines including cytokine-inducing agents |
| FR2896162B1 (fr) * | 2006-01-13 | 2008-02-15 | Sanofi Pasteur Sa | Emulsion huile dans eau thermoreversible |
| US20070224205A1 (en) | 2006-03-07 | 2007-09-27 | Powell Thomas J | Compositions that include hemagglutinin, methods of making and methods of use thereof |
| EP2004226A1 (en) * | 2006-03-24 | 2008-12-24 | Novartis Vaccines and Diagnostics GmbH & Co. KG | Storage of influenza vaccines without refrigeration |
| AU2007258874B2 (en) * | 2006-06-15 | 2013-11-14 | Seqirus UK Limited | Adjuvant-sparing multi-dose influenza vaccination regimen |
| CA2583555C (en) * | 2006-07-17 | 2020-01-07 | Glaxosmithkline Biologicals S.A. | Influenza vaccine |
| PT2043682E (pt) * | 2006-07-17 | 2014-07-11 | Glaxosmithkline Biolog Sa | Vacina da influenza |
| HRP20140488T1 (hr) | 2006-07-17 | 2014-07-04 | Glaxosmithkline Biologicals S.A. | Cjepivo protiv influence |
| PL2086582T3 (pl) * | 2006-10-12 | 2013-04-30 | Glaxosmithkline Biologicals Sa | Kompozycja zawierająca adiuwant w postaci emulsji typu olej w wodzie |
| KR101151202B1 (ko) | 2006-10-12 | 2012-06-11 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 수중유 에멀젼 애주번트를 포함하는 백신 |
| GB0622282D0 (en) | 2006-11-08 | 2006-12-20 | Novartis Ag | Quality control methods |
| EP1923070A1 (en) * | 2006-11-15 | 2008-05-21 | Intervet International BV | Vaccine for vaccinating feline against influenza virus |
| SG177141A1 (en) * | 2006-12-06 | 2012-01-30 | Novartis Ag | Vaccines including antigen from four strains of influenza virus |
| EP1938835A1 (en) * | 2006-12-29 | 2008-07-02 | Pevion Biotech AG | Non-specific immunostimulating agents |
| MX2009008926A (es) * | 2007-02-23 | 2009-09-14 | Baylor Res Inst | Aplicaciones terapeuticas de activacion de celulas que presentan antigeno humano por medio de detectina a-1. |
| US9452209B2 (en) | 2007-04-20 | 2016-09-27 | Glaxosmithkline Biologicals Sa | Influenza vaccine |
| NZ583377A (en) * | 2007-10-12 | 2013-11-29 | Csl Ltd | Method of eliciting an immune response against pandemic influenza virus |
| WO2009050586A1 (en) | 2007-10-19 | 2009-04-23 | Novartis Ag | Meningococcal vaccine formulations |
| GB0810305D0 (en) † | 2008-06-05 | 2008-07-09 | Novartis Ag | Influenza vaccination |
| JP2011506290A (ja) * | 2007-12-06 | 2011-03-03 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | インフルエンザ組成物 |
| US8426163B2 (en) * | 2007-12-07 | 2013-04-23 | National Health Research Institutes | Production of lipidated proteins in E. coli |
| US8466259B2 (en) * | 2007-12-07 | 2013-06-18 | National Health Research Institutes | Adjuvants |
| WO2009115917A2 (en) | 2008-03-18 | 2009-09-24 | Novartis Ag | Improvements in preparation of influenza virus vaccine antigens |
| WO2009128949A2 (en) | 2008-04-18 | 2009-10-22 | Vaxinnate Corporation | Compositions of dengue viral proteins and methods of use |
| GB0905570D0 (en) * | 2009-03-31 | 2009-05-13 | Novartis Ag | Combined vaccines |
| JP5712126B2 (ja) * | 2008-06-25 | 2015-05-07 | ノバルティス アーゲー | 遅延型追加刺激免疫処置に対する迅速な応答 |
| WO2010092479A2 (en) | 2009-02-10 | 2010-08-19 | Novartis Ag | Influenza vaccines with reduced amounts of squalene |
| AU2015203072B2 (en) * | 2009-02-10 | 2017-05-25 | Seqirus UK Limited | Influenza vaccine regimens for pandemic-associated strains |
| SI2396030T1 (sl) | 2009-02-10 | 2015-12-31 | Novartis Ag | Sheme dajanja cepiva proti gripi za seve, povezane s pandemijo |
| US8287880B2 (en) * | 2009-06-02 | 2012-10-16 | National Health Research Institutes | Lipidated vaccine against dengue virus infection |
| US8658176B2 (en) * | 2009-06-22 | 2014-02-25 | National Health Research Institutes | Lipidated tumor-associated antigens and immunotherapeutic compositions |
| EP2289575B1 (de) * | 2009-08-06 | 2017-07-05 | Biotronik VI Patent AG | Medizinisches Implantat enthaltend eine antioxidative Substanz |
| CN107582526A (zh) * | 2009-08-12 | 2018-01-16 | 希格默伊德药业有限公司 | 包含聚合物基质和油相的免疫调节组合物 |
| EP2308506A1 (en) * | 2009-10-02 | 2011-04-13 | Mucosis B.V. | Adjuvanted intranasal vaccine formulations |
| GB0918830D0 (en) | 2009-10-27 | 2009-12-09 | Glaxosmithkline Biolog Niederl | Process |
| GB0919117D0 (en) | 2009-10-30 | 2009-12-16 | Glaxosmithkline Biolog Sa | Process |
| AU2013202690B2 (en) * | 2009-12-03 | 2016-02-11 | Seqirus UK Limited | Hydrophilic filtration during manufacture of vaccine adjuvants |
| RS52748B (sr) | 2009-12-03 | 2013-08-30 | Novartis Ag | Cirkulacija komponenti tokom homogenizacije emulzija |
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| JP2011506290A (ja) * | 2007-12-06 | 2011-03-03 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | インフルエンザ組成物 |
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