NO20075774L - Nanopartikulaere kinazolinderivatformuleringer - Google Patents
Nanopartikulaere kinazolinderivatformuleringerInfo
- Publication number
- NO20075774L NO20075774L NO20075774A NO20075774A NO20075774L NO 20075774 L NO20075774 L NO 20075774L NO 20075774 A NO20075774 A NO 20075774A NO 20075774 A NO20075774 A NO 20075774A NO 20075774 L NO20075774 L NO 20075774L
- Authority
- NO
- Norway
- Prior art keywords
- quinazoline derivative
- nanoparticulate quinazoline
- nanoparticulate
- compositions
- derivative formulations
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 238000009472 formulation Methods 0.000 title 1
- 125000002294 quinazolinyl group Chemical class N1=C(N=CC2=CC=CC=C12)* 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 150000003246 quinazolines Chemical class 0.000 abstract 2
- 239000005551 L01XE03 - Erlotinib Substances 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- AAKJLRGGTJKAMG-UHFFFAOYSA-N erlotinib Chemical compound C=12C=C(OCCOC)C(OCCOC)=CC2=NC=NC=1NC1=CC=CC(C#C)=C1 AAKJLRGGTJKAMG-UHFFFAOYSA-N 0.000 abstract 1
- 229960001433 erlotinib Drugs 0.000 abstract 1
- 230000003463 hyperproliferative effect Effects 0.000 abstract 1
- 230000001613 neoplastic effect Effects 0.000 abstract 1
- -1 quinazoline amine Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67042905P | 2005-04-12 | 2005-04-12 | |
| PCT/US2006/013641 WO2006110811A1 (en) | 2005-04-12 | 2006-04-12 | Nanoparticulate quinazoline derivative formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20075774L true NO20075774L (no) | 2008-01-11 |
Family
ID=36659858
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20075774A NO20075774L (no) | 2005-04-12 | 2007-11-09 | Nanopartikulaere kinazolinderivatformuleringer |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8309133B2 (pt) |
| EP (1) | EP1871345B1 (pt) |
| JP (1) | JP2008535924A (pt) |
| KR (1) | KR20080002939A (pt) |
| CN (1) | CN101198314A (pt) |
| AU (1) | AU2006235487B2 (pt) |
| BR (1) | BRPI0607537A2 (pt) |
| CA (1) | CA2604735A1 (pt) |
| EA (1) | EA014611B1 (pt) |
| IL (1) | IL186609A (pt) |
| MX (1) | MX2007012778A (pt) |
| NO (1) | NO20075774L (pt) |
| WO (1) | WO2006110811A1 (pt) |
| ZA (1) | ZA200708702B (pt) |
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| JP2009543797A (ja) * | 2006-07-10 | 2009-12-10 | エラン ファーマ インターナショナル，リミティド | ナノ粒子ソラフェニブ製剤 |
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| WO2009024989A2 (en) * | 2007-08-17 | 2009-02-26 | Hetero Drugs Limited | A novel hydrated form of erlotinib free base and a process for preparation of erlotinib hydrochloride polymorph form a substantially free of polymorph form b |
| US20090131665A1 (en) * | 2007-08-23 | 2009-05-21 | Ales Gavenda | Process for the preparation of crystalline forms A, B and pure crystalline form a of erlotinib HCI |
| EP2190287B1 (en) * | 2007-09-10 | 2014-10-29 | Curis, Inc. | Tartrate salts or complexes of quinazoline based egfr inhibitors containing a zinc binding moiety |
| US20110182946A1 (en) * | 2008-03-17 | 2011-07-28 | Board Of Regents, The University Of Texas System | Formation of Nanostructured Particles of Poorly Water Soluble Drugs and Recovery by Mechanical Techniques |
| EP2158913A1 (en) | 2008-08-25 | 2010-03-03 | Ratiopharm GmbH | Pharmaceutical composition comprising N-[3-chhloro-4-[(3-fluorophenyl)methoxy]phenyl]6-(5[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furyl]-4-quinazolinamine |
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| AT10562U3 (de) * | 2008-12-05 | 2010-01-15 | Aop Orphan Pharmaceuticals Ag | Neuartige zusammensetzung zur behandlung einer essenziellen thrombozytämie |
| EP2213281A1 (en) | 2009-02-02 | 2010-08-04 | Ratiopharm GmbH | Pharmaceutical composition comprising N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride |
| WO2010102065A1 (en) | 2009-03-05 | 2010-09-10 | Bend Research, Inc. | Pharmaceutical compositions of dextran polymer derivatives |
| HUE032426T2 (en) | 2009-05-27 | 2017-09-28 | Alkermes Pharma Ireland Ltd | Inhibition of flake aggregation in nanoparticulate meloxicam formulations |
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| CN101874784B (zh) * | 2010-03-18 | 2011-12-14 | 贝沃特医药技术(上海)有限公司 | 析出结晶药物缓控释微球粒及其制备方法 |
| US8815294B2 (en) | 2010-09-03 | 2014-08-26 | Bend Research, Inc. | Pharmaceutical compositions of dextran polymer derivatives and a carrier material |
| US9084727B2 (en) | 2011-05-10 | 2015-07-21 | Bend Research, Inc. | Methods and compositions for maintaining active agents in intra-articular spaces |
| HK1202333A1 (en) * | 2011-11-11 | 2015-09-25 | Intellikine, Llc | Combination of kinase inhibitors and uses thereof |
| CN110123763A (zh) | 2012-06-21 | 2019-08-16 | 法斯瑞斯公司 | 靛玉红的奈米粒子、其衍生物以及制造和使用所述奈米粒子的方法 |
| WO2014118112A1 (en) | 2013-01-29 | 2014-08-07 | Synthon B.V. | Pharmaceutical composition comprising erlotinib hydrochloride |
| JP6445546B2 (ja) * | 2013-06-19 | 2018-12-26 | アイキュリス アンチ−インフェクティブ キュアズ ゲゼルシャフト ミット ベシュレンクテル ハフツング | 非晶質レテルモビル及び経口投与のためのその固形医薬製剤 |
| ES2640648T3 (es) | 2013-09-16 | 2017-11-03 | Astrazeneca Ab | Nanopartículas poliméricas terapéuticas y métodos para su fabricación y uso |
| WO2015071841A1 (en) | 2013-11-12 | 2015-05-21 | Druggability Technologies Holdings Limited | Complexes of dabigatran and its derivatives, process for the preparation thereof and pharmaceutical compositions containing them |
| RU2551359C9 (ru) * | 2013-11-28 | 2021-08-20 | Общество с ограниченной ответственностью "Мамонт Фарм" | Наноразмерная слабо закристаллизованная модификация 4-метил-N-[3-(4-метилимидазол-1-ил)-5-(трифторметил)фенил]-3-[(4-пиридин-3-илпиримидин-2-ил)амино]бензамида гидрохлорида моногидрата, способ ее получения и фармацевтическая композиция на ее основе |
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-
2006
- 2006-04-12 EP EP06740896A patent/EP1871345B1/en not_active Expired - Lifetime
- 2006-04-12 KR KR1020077025983A patent/KR20080002939A/ko not_active Ceased
- 2006-04-12 MX MX2007012778A patent/MX2007012778A/es not_active Application Discontinuation
- 2006-04-12 CN CNA2006800210164A patent/CN101198314A/zh active Pending
- 2006-04-12 BR BRPI0607537-1A patent/BRPI0607537A2/pt not_active IP Right Cessation
- 2006-04-12 US US11/402,264 patent/US8309133B2/en not_active Expired - Fee Related
- 2006-04-12 WO PCT/US2006/013641 patent/WO2006110811A1/en not_active Ceased
- 2006-04-12 CA CA002604735A patent/CA2604735A1/en not_active Abandoned
- 2006-04-12 JP JP2008506632A patent/JP2008535924A/ja active Pending
- 2006-04-12 EA EA200702214A patent/EA014611B1/ru not_active IP Right Cessation
- 2006-04-12 AU AU2006235487A patent/AU2006235487B2/en not_active Ceased
-
2007
- 2007-10-11 ZA ZA200708702A patent/ZA200708702B/xx unknown
- 2007-10-11 IL IL186609A patent/IL186609A/en not_active IP Right Cessation
- 2007-11-09 NO NO20075774A patent/NO20075774L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| MX2007012778A (es) | 2008-01-11 |
| IL186609A0 (en) | 2008-01-20 |
| EA014611B1 (ru) | 2010-12-30 |
| EP1871345B1 (en) | 2012-08-01 |
| US20060246142A1 (en) | 2006-11-02 |
| AU2006235487A1 (en) | 2006-10-19 |
| US8309133B2 (en) | 2012-11-13 |
| EA200702214A1 (ru) | 2008-04-28 |
| IL186609A (en) | 2012-12-31 |
| KR20080002939A (ko) | 2008-01-04 |
| CN101198314A (zh) | 2008-06-11 |
| WO2006110811A1 (en) | 2006-10-19 |
| JP2008535924A (ja) | 2008-09-04 |
| AU2006235487B2 (en) | 2011-12-22 |
| ZA200708702B (en) | 2008-11-26 |
| CA2604735A1 (en) | 2006-10-19 |
| BRPI0607537A2 (pt) | 2009-09-15 |
| EP1871345A1 (en) | 2008-01-02 |
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