NO20080607L - Fremgangsmate for fremstilling av losartan og nye mellomprodukter som er anvendelige i en slik fremgangsmate - Google Patents
Fremgangsmate for fremstilling av losartan og nye mellomprodukter som er anvendelige i en slik fremgangsmateInfo
- Publication number
- NO20080607L NO20080607L NO20080607A NO20080607A NO20080607L NO 20080607 L NO20080607 L NO 20080607L NO 20080607 A NO20080607 A NO 20080607A NO 20080607 A NO20080607 A NO 20080607A NO 20080607 L NO20080607 L NO 20080607L
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- formula
- losartan
- compound
- novel intermediates
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 239000002083 C09CA01 - Losartan Substances 0.000 title abstract 2
- KJJZZJSZUJXYEA-UHFFFAOYSA-N losartan Chemical compound CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C=2[N]N=NN=2)C=C1 KJJZZJSZUJXYEA-UHFFFAOYSA-N 0.000 title abstract 2
- 229960004773 losartan Drugs 0.000 title abstract 2
- 239000000543 intermediate Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000002129 sartan derivative Substances 0.000 abstract 3
- 150000003898 sartan derivatives Chemical class 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000006763 (C3-C9) cycloalkyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05014451A EP1741711A1 (de) | 2005-07-04 | 2005-07-04 | Verfahren zur Herstellung von Losartanderivaten durch Chlorierung und Reduktion der entsprechenden 1H-imidazol-5-carbaldehyde |
| PCT/EP2006/006040 WO2007003280A1 (en) | 2005-07-04 | 2006-06-22 | A process for the preparation of losartan derivatives by chlorination and reduction of the respective 1h-imidazole-5-carbaldehydes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20080607L true NO20080607L (no) | 2008-02-01 |
Family
ID=35395891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20080607A NO20080607L (no) | 2005-07-04 | 2008-02-01 | Fremgangsmate for fremstilling av losartan og nye mellomprodukter som er anvendelige i en slik fremgangsmate |
Country Status (6)
| Country | Link |
|---|---|
| EP (2) | EP1741711A1 (de) |
| AT (1) | ATE424397T1 (de) |
| DE (1) | DE602006005488D1 (de) |
| NO (1) | NO20080607L (de) |
| SI (1) | SI1899328T1 (de) |
| WO (1) | WO2007003280A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102786399A (zh) * | 2011-05-16 | 2012-11-21 | 湖南斯威森生化技术有限公司 | 一种本芴醇中间体2,7-二氯-4-氯乙酰芴新合成方法 |
| CN113929666A (zh) * | 2021-09-30 | 2022-01-14 | 宁波美诺华药业股份有限公司 | 一种洛沙坦立体异构体杂质合成方法 |
| CN116751167B (zh) * | 2023-07-03 | 2025-09-23 | 苏州诚和医药化学有限公司 | 一种(e)-4-(1-苄基-2-甲基-1h-咪唑-5-基)-3-(乙氧基酰基)丁-3-烯酸的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4132633A1 (de) * | 1991-10-01 | 1993-04-08 | Bayer Ag | Cyclisch substituierte imidazolyl-propensaeurederivate |
| WO2003093262A2 (en) * | 2002-04-29 | 2003-11-13 | Teva Pharmaceutical Industries Ltd. | Processes for preparing losartan and losartan potassium |
| ITMI20032069A1 (it) * | 2003-10-23 | 2005-04-24 | Dinamite Dipharma S P A In Forma A Bbreviata Diph | Procedimento per la preparazione di derivati benzilmidazolici. |
-
2005
- 2005-07-04 EP EP05014451A patent/EP1741711A1/de not_active Withdrawn
-
2006
- 2006-06-22 DE DE602006005488T patent/DE602006005488D1/de active Active
- 2006-06-22 WO PCT/EP2006/006040 patent/WO2007003280A1/en not_active Ceased
- 2006-06-22 AT AT06754522T patent/ATE424397T1/de not_active IP Right Cessation
- 2006-06-22 EP EP06754522A patent/EP1899328B1/de active Active
- 2006-06-22 SI SI200630264T patent/SI1899328T1/sl unknown
-
2008
- 2008-02-01 NO NO20080607A patent/NO20080607L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007003280A1 (en) | 2007-01-11 |
| EP1899328B1 (de) | 2009-03-04 |
| EP1741711A1 (de) | 2007-01-10 |
| EP1899328A1 (de) | 2008-03-19 |
| ATE424397T1 (de) | 2009-03-15 |
| DE602006005488D1 (de) | 2009-04-16 |
| SI1899328T1 (sl) | 2009-06-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |