NO20082410L - Biomarkorer for anti-nogo-a antistoffbehandling ved spinalstrengskader - Google Patents

Biomarkorer for anti-nogo-a antistoffbehandling ved spinalstrengskader

Info

Publication number
NO20082410L
NO20082410L NO20082410A NO20082410A NO20082410L NO 20082410 L NO20082410 L NO 20082410L NO 20082410 A NO20082410 A NO 20082410A NO 20082410 A NO20082410 A NO 20082410A NO 20082410 L NO20082410 L NO 20082410L
Authority
NO
Norway
Prior art keywords
nogo
spinal cord
antibody treatment
biomarkers
cord injury
Prior art date
Application number
NO20082410A
Other languages
English (en)
Inventor
Anis Khusro Mir
Lisa Schnell
Anu Kinnunen
Martin Schwab
Laura Montani
Leda Dimou
Original Assignee
Novartis Ag University Of Zurich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag University Of Zurich filed Critical Novartis Ag University Of Zurich
Publication of NO20082410L publication Critical patent/NO20082410L/no

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/44—Multiple drug resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Denne angivelsen av denne oppfinnelsen bekrefter, ved nivået av genekspresjon, den skadede ryggmargen og motorisk hjernebark som de primære setene for virkning av anti-Nogo-A-antistoffbehandlingen benyttet intratekalt. Angivelsen tilveiebringer videre fremgangsmåter for å forutsi responsen av et individ til et medikament omfattende et anti-Nogo-A-antistoff.
NO20082410A 2005-11-16 2008-05-28 Biomarkorer for anti-nogo-a antistoffbehandling ved spinalstrengskader NO20082410L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73741005P 2005-11-16 2005-11-16
PCT/EP2006/068457 WO2007057395A2 (en) 2005-11-16 2006-11-14 Biomarkers for anti-nogo-a antibody treatment in spinal cord injury

Publications (1)

Publication Number Publication Date
NO20082410L true NO20082410L (no) 2008-07-22

Family

ID=37671369

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20082410A NO20082410L (no) 2005-11-16 2008-05-28 Biomarkorer for anti-nogo-a antistoffbehandling ved spinalstrengskader

Country Status (12)

Country Link
US (1) US20080317741A1 (no)
EP (2) EP1952147A2 (no)
JP (1) JP2009515542A (no)
KR (1) KR20080073748A (no)
CN (1) CN101310183A (no)
AU (1) AU2006314528A1 (no)
BR (1) BRPI0618609A2 (no)
CA (1) CA2627966A1 (no)
MX (1) MX2008006355A (no)
NO (1) NO20082410L (no)
RU (1) RU2008123384A (no)
WO (1) WO2007057395A2 (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2427212B1 (en) * 2009-05-08 2017-08-23 Vaccinex, Inc. Anti-cd100 antibodies and methods for using the same
US8828390B2 (en) 2010-07-09 2014-09-09 Universitat Zurich Uses of NOGO-A inhibitors and related methods
US10208349B2 (en) 2011-01-07 2019-02-19 Ucb Biopharma Sprl Lipocalin 2 as a biomarker for IL-17 inhibitor therapy efficacy
EA029023B1 (ru) 2011-10-11 2018-01-31 Вэксинекс, Инк. Применение молекул, связывающих семафорин-4d, для модуляции проницаемости гематоэнцефалического барьера
KR101446514B1 (ko) * 2012-12-07 2014-10-06 한국과학기술연구원 생체 이식형 신경교상흔 감지 센서
CN112798698B (zh) * 2020-11-30 2022-08-23 潍坊学院 一种基于主成分差异度挑选生物标志物的油指纹识别方法
CN114409779B (zh) * 2022-01-27 2023-06-09 天津长和生物技术有限公司 NogoA抗体及其在脊髓损伤中的应用

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Also Published As

Publication number Publication date
US20080317741A1 (en) 2008-12-25
RU2008123384A (ru) 2009-12-27
WO2007057395A3 (en) 2007-11-08
JP2009515542A (ja) 2009-04-16
EP1952147A2 (en) 2008-08-06
EP2299267A3 (en) 2011-05-04
WO2007057395A2 (en) 2007-05-24
CN101310183A (zh) 2008-11-19
MX2008006355A (es) 2008-10-17
EP2299267A2 (en) 2011-03-23
KR20080073748A (ko) 2008-08-11
CA2627966A1 (en) 2007-05-24
BRPI0618609A2 (pt) 2011-09-06
AU2006314528A1 (en) 2007-05-24

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