NO20082986L - Nye, acylisk substituerte furopyrimidinderivater og anvendelse derav for behandling av kardiovaskulaere lidelser - Google Patents

Nye, acylisk substituerte furopyrimidinderivater og anvendelse derav for behandling av kardiovaskulaere lidelser

Info

Publication number
NO20082986L
NO20082986L NO20082986A NO20082986A NO20082986L NO 20082986 L NO20082986 L NO 20082986L NO 20082986 A NO20082986 A NO 20082986A NO 20082986 A NO20082986 A NO 20082986A NO 20082986 L NO20082986 L NO 20082986L
Authority
NO
Norway
Prior art keywords
treatment
acyl
novel
cardiovascular disorders
furopyrimidine derivatives
Prior art date
Application number
NO20082986A
Other languages
English (en)
Norwegian (no)
Inventor
Andreas Knorr
Johannes-Peter Stasch
Rudolf Schohe-Loop
Karl-Heinz Schlemmer
Mario Jeske
Lars Barfacker
Thomas Lampe
Eva-Maria Becker
Raimund Kast
Hartmut Beck
Joachim Schuhmacher
Friederike Stoll
Martina Klein
Metin Akbaba
Alexander Hillisch
Gunter Karig
Mark Meininghaus
Original Assignee
Bayer Ip Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ip Gmbh filed Critical Bayer Ip Gmbh
Publication of NO20082986L publication Critical patent/NO20082986L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20082986A 2005-12-21 2008-07-02 Nye, acylisk substituerte furopyrimidinderivater og anvendelse derav for behandling av kardiovaskulaere lidelser NO20082986L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005061170A DE102005061170A1 (de) 2005-12-21 2005-12-21 Neue, acyclisch substituierte Furopyrimidin-Derivate und ihre Verwendung
PCT/EP2006/011826 WO2007079862A1 (de) 2005-12-21 2006-12-08 Neue, acyclisch substituierte furopyrimidin-derivate und ihre verwendung zur behandlung von kardiovaskulären erkrankungen

Publications (1)

Publication Number Publication Date
NO20082986L true NO20082986L (no) 2008-07-02

Family

ID=37876878

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20082986A NO20082986L (no) 2005-12-21 2008-07-02 Nye, acylisk substituerte furopyrimidinderivater og anvendelse derav for behandling av kardiovaskulaere lidelser

Country Status (31)

Country Link
US (1) US8183246B2 (pl)
EP (1) EP1966217B1 (pl)
JP (1) JP5254032B2 (pl)
KR (1) KR101429777B1 (pl)
CN (1) CN101384603B (pl)
AR (1) AR058108A1 (pl)
AU (1) AU2006334856B2 (pl)
BR (1) BRPI0620317A2 (pl)
CA (1) CA2633701C (pl)
CR (1) CR10092A (pl)
DE (1) DE102005061170A1 (pl)
DK (1) DK1966217T3 (pl)
DO (1) DOP2006000280A (pl)
EC (1) ECSP088569A (pl)
ES (1) ES2418855T3 (pl)
GT (1) GT200800117A (pl)
IL (1) IL192062A0 (pl)
MA (1) MA30039B1 (pl)
NO (1) NO20082986L (pl)
NZ (1) NZ569214A (pl)
PE (1) PE20071168A1 (pl)
PL (1) PL1966217T3 (pl)
PT (1) PT1966217E (pl)
RU (1) RU2454419C2 (pl)
SV (1) SV2009002953A (pl)
TN (1) TNSN08279A1 (pl)
TW (1) TWI405764B (pl)
UA (1) UA94080C2 (pl)
UY (1) UY30046A1 (pl)
WO (1) WO2007079862A1 (pl)
ZA (1) ZA200805385B (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007019691A1 (de) * 2007-04-26 2008-10-30 Bayer Healthcare Ag Verwendung von acyclisch substituierten Furopyrimidin-Derivaten zur Behandlung der pulmonalen arteriellen Hypertonie
DE102007027799A1 (de) * 2007-06-16 2008-12-18 Bayer Healthcare Ag Substituierte Furopyrimidine und ihre Verwendung
DE102007051762A1 (de) * 2007-10-30 2009-05-07 Bayer Healthcare Ag Substituierte Pyrrolotriazine und ihre Verwendung
DE102007054786A1 (de) * 2007-11-16 2009-05-20 Bayer Healthcare Ag Trisubstituierte Furopyrimidine und ihre Verwendung
WO2013168759A1 (ja) 2012-05-10 2013-11-14 武田薬品工業株式会社 芳香環化合物
US9505772B2 (en) 2012-05-10 2016-11-29 Takeda Pharmaceutical Company Limited Aromatic ring compound
EP3562828B1 (en) 2016-12-28 2026-03-18 Dart Neuroscience LLC Substituted pyrazolopyrimidinone compounds as pde2 inhibitors
MX2020005447A (es) 2017-11-27 2020-12-03 Dart Neuroscience Llc Compuestos de furanopirimidina sustituida como inhibidores de pde1.
ES3065954T3 (en) * 2019-05-13 2026-05-08 Relay Therapeutics Inc Fgfr inhibitors and methods of use thereof
KR102094337B1 (ko) 2019-10-01 2020-03-27 안문호 금속이물질 제거장치
TWI924727B (zh) 2020-11-18 2026-05-11 美商傳達治療有限公司 Ｆｇｆｒ抑制劑及其製造及使用方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3577420A (en) 1968-01-05 1971-05-04 Pfizer Certain 4-aminofuro(2,3-d)pyrimidines
ES2219033T3 (es) 1998-07-22 2004-11-16 Daiichi Suntory Pharma Co., Ltd. Inhibidores de nf-kappa b que contienen derivados de indano como ingrediente activo.
HK1045306A1 (zh) 1999-06-03 2002-11-22 Abbott Laboratories 抑制细胞黏附的抗炎化合物
WO2001021206A1 (en) 1999-09-17 2001-03-29 Suntory Limited PREVENTIVES OR REMEDIES FOR MYOCARDITIS, DILATED CARDIOMYOPATHY AND CARDIAC INSUFFICIENCY CONTAINING NF-λB INHIBITORS AS THE ACTIVE INGREDIENT
CA2449188A1 (en) 2001-05-14 2002-11-21 Novartis Ag Oxazolo-and furopyrimidines and their use in medicaments against tumors
DE10141212A1 (de) 2001-08-22 2003-03-06 Bayer Ag Neue 4-Aminofuropyrimidine und ihre Verwendung
AU2002333524A1 (en) 2001-09-11 2003-03-24 Glaxosmithkline K.K. Furo-and thienopyrimidine derivatives as angiogenesis inhibitors
DE10148883A1 (de) * 2001-10-04 2003-04-10 Merck Patent Gmbh Pyrimidinderivate
US20030225098A1 (en) * 2002-03-21 2003-12-04 Hirst Gavin C. Kinase inhibitors
KR20050091462A (ko) 2004-03-12 2005-09-15 한국과학기술연구원 푸로피리미딘 화합물 및 이를 포함하는 ｄｄｒ2 티로신키나아제 활성 저해제
CA2568304A1 (en) 2004-06-10 2005-12-22 Xention Discovery Limited Furanopyrimidine compounds effective as potassium channel inhibitors
JP2008505084A (ja) * 2004-06-29 2008-02-21 アムゲン インコーポレイティッド フラノピリミジン

Also Published As

Publication number Publication date
CN101384603B (zh) 2012-08-01
GT200800117A (es) 2009-12-16
EP1966217B1 (de) 2013-05-08
RU2454419C2 (ru) 2012-06-27
RU2008129363A (ru) 2010-01-27
DK1966217T3 (da) 2013-08-05
AU2006334856B2 (en) 2013-04-04
KR20080081323A (ko) 2008-09-09
AU2006334856A1 (en) 2007-07-19
TNSN08279A1 (en) 2009-10-30
PT1966217E (pt) 2013-07-12
AR058108A1 (es) 2008-01-23
CR10092A (es) 2008-10-08
DOP2006000280A (es) 2007-07-31
ECSP088569A (es) 2008-08-29
JP2009520713A (ja) 2009-05-28
UY30046A1 (es) 2007-07-31
EP1966217A1 (de) 2008-09-10
PL1966217T3 (pl) 2013-09-30
PE20071168A1 (es) 2008-02-07
SV2009002953A (es) 2009-04-28
CN101384603A (zh) 2009-03-11
TWI405764B (zh) 2013-08-21
ES2418855T3 (es) 2013-08-16
BRPI0620317A2 (pt) 2011-11-08
JP5254032B2 (ja) 2013-08-07
ZA200805385B (en) 2009-10-28
HK1130054A1 (en) 2009-12-18
CA2633701A1 (en) 2007-07-19
US20090318475A1 (en) 2009-12-24
MA30039B1 (fr) 2008-12-01
UA94080C2 (ru) 2011-04-11
TW200745132A (en) 2007-12-16
DE102005061170A1 (de) 2007-07-05
WO2007079862A1 (de) 2007-07-19
IL192062A0 (en) 2008-12-29
KR101429777B1 (ko) 2014-08-19
NZ569214A (en) 2011-07-29
CA2633701C (en) 2014-05-27
US8183246B2 (en) 2012-05-22

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Legal Events

Date Code Title Description
CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: BAYER INTELLECTUAL PROPERTY GMBH, DE

FC2A Withdrawal, rejection or dismissal of laid open patent application