NO20083090L - Nye kombinasjoner av anticholinergika, beta2-adrenospeptoragonister, antilukotriner (leukotrinreseptorantagonister), glukocorticosteroids og/eller PDE 4-inhibitorer for behandling av inflammatoriske sykdommer - Google Patents
Nye kombinasjoner av anticholinergika, beta2-adrenospeptoragonister, antilukotriner (leukotrinreseptorantagonister), glukocorticosteroids og/eller PDE 4-inhibitorer for behandling av inflammatoriske sykdommerInfo
- Publication number
- NO20083090L NO20083090L NO20083090A NO20083090A NO20083090L NO 20083090 L NO20083090 L NO 20083090L NO 20083090 A NO20083090 A NO 20083090A NO 20083090 A NO20083090 A NO 20083090A NO 20083090 L NO20083090 L NO 20083090L
- Authority
- NO
- Norway
- Prior art keywords
- anticholinergics
- treatment
- antilukotrins
- glucocorticosteroids
- beta2
- Prior art date
Links
- 239000000556 agonist Substances 0.000 title abstract 2
- 229940065524 anticholinergics inhalants for obstructive airway diseases Drugs 0.000 title abstract 2
- 239000000812 cholinergic antagonist Substances 0.000 title abstract 2
- 208000027866 inflammatory disease Diseases 0.000 title abstract 2
- 229940123932 Phosphodiesterase 4 inhibitor Drugs 0.000 title 1
- 102000014974 beta2-adrenergic receptor activity proteins Human genes 0.000 title 1
- 108040006828 beta2-adrenergic receptor activity proteins Proteins 0.000 title 1
- 239000002587 phosphodiesterase IV inhibitor Substances 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 208000025747 Rheumatic disease Diseases 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 239000003862 glucocorticoid Substances 0.000 abstract 1
- 208000030603 inherited susceptibility to asthma Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 208000023504 respiratory system disease Diseases 0.000 abstract 1
- 230000000552 rheumatic effect Effects 0.000 abstract 1
- 229940037128 systemic glucocorticoids Drugs 0.000 abstract 1
Classifications
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- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
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- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Transplantation (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Foreliggende oppfinnelse angår nye kombinasjoner basert på antikolinergiske midler, ß2-adrenoseptor agonister, PDE 4 inhibitorer, glukokortikoider, og leukotrien-reseptor antagonister, fremgangsmåter for deres fremstilling og deres anvendelse for behandling av inflammatoriske sykdommer, foretrukket respiratoriske sykdommer som bronkial astma og kronisk obstruktiv lungesykdom (COPD) eller reumatiske eller autoimmune sykdommer.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75205805P | 2005-12-21 | 2005-12-21 | |
| PCT/EP2006/011536 WO2007071313A2 (en) | 2005-12-21 | 2006-12-01 | Combination of anticholinergics, glucocorticoids, beta2-ag0nists, pde4 inhibitor and antileukotriene for the treatment of inflammatory diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20083090L true NO20083090L (no) | 2008-09-11 |
Family
ID=37872413
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20083090A NO20083090L (no) | 2005-12-21 | 2008-07-09 | Nye kombinasjoner av anticholinergika, beta2-adrenospeptoragonister, antilukotriner (leukotrinreseptorantagonister), glukocorticosteroids og/eller PDE 4-inhibitorer for behandling av inflammatoriske sykdommer |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US8048910B2 (no) |
| EP (2) | EP1971369B1 (no) |
| JP (1) | JP5107933B2 (no) |
| CN (1) | CN101321539B (no) |
| AT (1) | ATE439834T1 (no) |
| AU (1) | AU2006329042B2 (no) |
| CA (2) | CA2824075C (no) |
| CY (2) | CY1110519T1 (no) |
| DE (1) | DE602006008665D1 (no) |
| DK (2) | DK2098248T3 (no) |
| ES (2) | ES2389231T3 (no) |
| HR (2) | HRP20090498T1 (no) |
| NO (1) | NO20083090L (no) |
| NZ (2) | NZ591969A (no) |
| PL (2) | PL2098248T3 (no) |
| PT (2) | PT2098248E (no) |
| RU (1) | RU2465915C2 (no) |
| SI (2) | SI2098248T1 (no) |
| WO (1) | WO2007071313A2 (no) |
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| EP1713473B1 (en) * | 2004-02-06 | 2013-03-13 | MEDA Pharma GmbH & Co. KG | The combination of anticholinergics and glucocorticoids for the long-term treatment of asthma and copd |
| EP3669878A1 (en) | 2006-08-10 | 2020-06-24 | Roy C. Levitt | Localized therapy of lower airways inflammatory disorders with proinflammatory cytokine inhibitors |
| EP1894568A1 (en) * | 2006-08-31 | 2008-03-05 | Novartis AG | Pharmaceutical compositions for the treatment of inflammatory or obstructive airway diseases |
| US9623000B2 (en) | 2008-07-31 | 2017-04-18 | Dekel Pharmaceuticals Ltd | Compositions and methods for treating inflammatory disorders |
| CN101474191B (zh) * | 2009-01-21 | 2011-03-23 | 李虎山 | 一种治疗哮喘和慢性阻塞性肺病的药物组合物 |
| MX337126B (es) | 2009-05-29 | 2016-02-12 | Pearl Therapeutics Inc | Administracion respiratoria de agentes activos. |
| US8815258B2 (en) | 2009-05-29 | 2014-08-26 | Pearl Therapeutics, Inc. | Compositions, methods and systems for respiratory delivery of two or more active agents |
| WO2010144628A2 (en) * | 2009-06-09 | 2010-12-16 | Elevation Pharmaceuticals, Inc. | Treatment of chronic obstructive pulmonary disease with nebulized beta 2-agonist or combined nebulized beta 2-agonist and anticholinergic administration |
| UA113832C2 (xx) * | 2009-12-23 | 2017-03-27 | Комбінаційна терапія для хозл | |
| KR20130050952A (ko) | 2010-06-16 | 2013-05-16 | 브루스 챈들러 메이 | 인플루엔자, 감기 및 염증의 치료에서 레보세티리진 및 몬테루카스트의 용도 |
| CA2812952A1 (en) * | 2010-09-27 | 2012-04-12 | Microdose Therapeutx, Inc. | Methods and compositions for disease treatment using inhalation |
| CN102416179B (zh) | 2010-09-28 | 2014-05-07 | 益得生物科技股份有限公司 | 用于哮喘的吸入性复方组合物 |
| RU2642624C2 (ru) * | 2010-10-12 | 2018-01-25 | Сипла Лимитед | Фармацевтическая композиция |
| WO2012107364A1 (en) * | 2011-02-07 | 2012-08-16 | Scipharm Sàrl | Novel composition for the treatment of cystic fibrosis |
| CN102247380A (zh) * | 2011-08-19 | 2011-11-23 | 北京阜康仁生物制药科技有限公司 | 一种以布地奈德与茚达特罗为活性成分的复方制剂 |
| EP2948148B1 (en) | 2013-01-28 | 2020-07-29 | Incozen Therapeutics Pvt. Ltd. | Methods of treating autoimmune, respiratory and inflammatory disorders by inhalation of roflumilast n-oxide |
| MX382776B (es) | 2013-03-13 | 2025-03-13 | Inflammatory Response Res Inc | Uso de levocetirizina y montelukast en el tratamiento de lesion traumatica. |
| RU2015134423A (ru) | 2013-03-13 | 2017-04-26 | Инфламматори Респонс Ресёрч, Инк. | Применение левоцитиризина и монтелукаста при лечении аутоиммуных расстройств |
| WO2014164285A2 (en) | 2013-03-13 | 2014-10-09 | Inflammatory Response Research, Inc. | Use of levocetirizine and montelukast in the treatment of vasculitis |
| KR102391332B1 (ko) | 2013-03-15 | 2022-04-26 | 펄 테라퓨틱스 인코포레이티드 | 미립자 결정질 재료를 컨디셔닝하는 방법 및 시스템 |
| WO2016044095A1 (en) | 2014-09-15 | 2016-03-24 | Inflammatory Response Research, Inc. | Levocetirizine and montelukast in the treatment of inflammation mediated conditions |
| US10058661B2 (en) | 2014-12-04 | 2018-08-28 | Norton (Waterford) Limited | Inhalation monitoring system and method |
| JP6528314B2 (ja) * | 2015-03-20 | 2019-06-12 | 国立大学法人山口大学 | A(H1N1)pdm09インフルエンザウイルス感染による気管支喘息の予防又は改善剤 |
| JP6674748B2 (ja) * | 2015-05-27 | 2020-04-01 | 花王株式会社 | Glp−1分泌促進剤 |
| WO2019060595A1 (en) | 2017-09-20 | 2019-03-28 | Teva Branded Pharmaceutical Products R&D, Inc. | INHALABLE DRY POWDER MEDICINAL PRODUCT COMPRISING GLYCOPYRRONIUM |
| CN111228257A (zh) * | 2020-03-03 | 2020-06-05 | 中国人民解放军南部战区总医院 | 咯利普兰在制备治疗脓毒症心功能障碍的药物中的应用 |
| US11160814B1 (en) * | 2020-05-07 | 2021-11-02 | Ensemlble Group Holdings | Methods of treatment for disease from coronavirus exposure |
| WO2021236518A1 (en) | 2020-05-19 | 2021-11-25 | IRR, Inc. | Levocetirizine and montelukast in the treatment of sepsis and symptoms thereof |
| EP4209219A1 (en) * | 2022-01-07 | 2023-07-12 | MetrioPharm AG | Combination of budesonide and 5-amino-2,3-dihydro-1,4-phtalazinedione |
| CN118105342A (zh) * | 2023-09-28 | 2024-05-31 | 立生医药(苏州)有限公司 | 一种含pde-4抑制剂的无菌吸入用混悬液及其制备方法和应用 |
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| ES2176252T3 (es) | 1993-07-02 | 2002-12-01 | Altana Pharma Ag | Benzamidas sustituidas con fluoro-alcoxi y su utilizacion como agentes inhibidores de fosfodiesterasas de nucleotidos ciclicos. |
| WO1998000016A1 (en) | 1996-07-01 | 1998-01-08 | Sepracor, Inc. | Methods and compositions for treating urinary incontinence using enantiomerically enriched (r,r)-glycopyrrolate |
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| US6384038B1 (en) | 1998-04-14 | 2002-05-07 | Sepracor Inc. | Methods and compositions using cetirizine in combination with leukotriene inhibitors or decongestants |
| WO1999062720A1 (fr) * | 1998-05-29 | 1999-12-09 | Citizen Watch Co., Ltd. | Procede permettant de soumettre une imprimante a jet d'encre a un traitement de pre-utilisation |
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| GB0008660D0 (en) * | 2000-04-07 | 2000-05-31 | Arakis Ltd | The treatment of respiratory diseases |
| GB0009584D0 (en) * | 2000-04-18 | 2000-06-07 | Glaxo Group Ltd | Pharmaceutical compositions |
| GB0009583D0 (en) | 2000-04-18 | 2000-06-07 | Glaxo Group Ltd | Respiratory formulations |
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