NO20083378L - Syntese av glukagon-lignende peptid - Google Patents

Syntese av glukagon-lignende peptid

Info

Publication number: NO20083378L
Authority: NO; Norway
Prior art keywords: peptide; glucagon; synthesis; devised; new method
Prior art date: 2006-02-08

Application number

NO20083378A

Other languages

English (en)

Norwegian (no)

Inventor

Matthieu Giraud

Oleg Werbitzky

Stephane Varray

Carsten Meininghaus

Original Assignee

Lonza Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-02-08

Filing date

2008-08-04

Publication date

2008-10-31

2008-08-04 Application filed by Lonza Ag filed Critical Lonza Ag

2008-10-31 Publication of NO20083378L publication Critical patent/NO20083378L/no

Links

108010088406 Glucagon-Like Peptides Proteins 0.000 title 1
230000015572 biosynthetic process Effects 0.000 title 1
238000003786 synthesis reaction Methods 0.000 title 1
102100025101 GATA-type zinc finger protein 1 Human genes 0.000 abstract 1
101710198884 GATA-type zinc finger protein 1 Proteins 0.000 abstract 1
DTHNMHAUYICORS-KTKZVXAJSA-N Glucagon-like peptide 1 Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC=1N=CNC=1)[C@@H](C)O)[C@@H](C)O)C(C)C)C1=CC=CC=C1 DTHNMHAUYICORS-KTKZVXAJSA-N 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1
230000002194 synthesizing effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/10—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using coupling agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Endocrinology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Diabetes (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Obesity (AREA)
Emergency Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Hematology (AREA)
Analytical Chemistry (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

NO20083378A 2006-02-08 2008-08-04 Syntese av glukagon-lignende peptid NO20083378L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP06002537		2006-02-08
PCT/EP2007/000198 WO2007090496A1 (en)	2006-02-08	2007-01-11	Synthesis of glucagon-like peptide

Publications (1)

Publication Number	Publication Date
NO20083378L true NO20083378L (no)	2008-10-31

Family

ID=37697824

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20083378A NO20083378L (no)	2006-02-08	2008-08-04	Syntese av glukagon-lignende peptid

Country Status (19)

Country	Link
US (2)	US8445433B2 (de)
EP (1)	EP1987052B1 (de)
JP (1)	JP5199126B2 (de)
KR (1)	KR101297942B1 (de)
CN (1)	CN101379075B (de)
AT (1)	ATE507235T1 (de)
AU (1)	AU2007214088B2 (de)
BR (1)	BRPI0707599A2 (de)
CA (1)	CA2641053A1 (de)
DE (1)	DE602007014184D1 (de)
DK (1)	DK1987052T3 (de)
ES (1)	ES2364982T3 (de)
IL (1)	IL193134A (de)
MX (1)	MX2008010136A (de)
NO (1)	NO20083378L (de)
PT (1)	PT1987052E (de)
TW (1)	TWI404724B (de)
WO (1)	WO2007090496A1 (de)
ZA (1)	ZA200806690B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN101835794A (zh)	2007-10-27	2010-09-15	霍夫曼-拉罗奇有限公司	使用固相和溶液相组合技术的促胰岛素肽合成法
EP2222695A2 (de) *	2007-12-11	2010-09-01	F. Hoffmann-La Roche AG	Synthese eines insulinotropen peptids mithilfe von feststoff- und flüssigphasenkombinationsverfahren
EP2424888A2 (de) *	2009-05-01	2012-03-07	F. Hoffmann-La Roche AG	Synthese insulinotroper peptide unter anwendung von fest- und flüssigphasenkombinationsverfahren
CN102250235A (zh) *	2011-06-23	2011-11-23	成都圣诺科技发展有限公司	奈西立肽的制备方法
GB201310921D0 (en)	2013-06-19	2013-07-31	Chemical & Biopharmaceutical Lab Of Patras S A	Peptide-resin conjugate and use thereof
CN105849123A (zh) *	2013-12-13	2016-08-10	免疫医疗有限公司	蛋白酶抗性肽
CN104017064B (zh) *	2014-06-13	2016-08-24	杭州阿诺生物医药科技股份有限公司	一种制备特立帕肽的方法
GR20140100479A (el)	2014-09-23	2016-05-05	Novetide, Ltd.,	Συνθεση λιραγλουτιδης
CN104356221B (zh) *	2014-10-24	2018-06-26	杭州阿诺生物医药科技股份有限公司	一种制备培西加南的方法
EP3433267B1 (de) *	2016-03-23	2022-08-24	Bachem Holding AG	Verfahren zur herstellung glucagonähnlicher peptide
EP3692056A1 (de)	2017-10-04	2020-08-12	Chemical & Biopharmaceutical Laboratories of Patras S.A.	Verfahren zur herstellung eines glucagonähnlichen peptids
WO2020127476A1 (en)	2018-12-19	2020-06-25	Krka, D.D., Novo Mesto	Pharmaceutical composition comprising glp-1 analogue
WO2020190757A1 (en)	2019-03-15	2020-09-24	Novetide Ltd.	Improved processes for the preparation of semaglutide
WO2021123228A1 (en)	2019-12-18	2021-06-24	Krka, D.D., Novo Mesto	Pharmaceutical composition comprising glp-1 analogue
EP4085077A4 (de)	2019-12-31	2024-01-17	Beijing QL Biopharmaceutical Co., Ltd.	Fusionsproteine aus glp-1 und gdf15 und konjugate davon
AR122579A1 (es) *	2020-06-12	2022-09-21	Lilly Co Eli	Proceso para preparar un agonista dual glp-1 / glucagón
CN114729060B (zh)	2020-09-30	2022-11-25	北京质肽生物医药科技有限公司	多肽缀合物和使用方法
KR20230129472A (ko) *	2021-01-04	2023-09-08	바이오콘 리미티드	테두글루타이드 합성
CN114249808B (zh) *	2021-12-27	2024-11-12	江苏诺泰澳赛诺生物制药股份有限公司	一种Cagrilintide的合成方法
EP4323413A4 (de)	2022-03-30	2025-10-15	Beijing Ql Biopharmaceutical Co Ltd	Flüssige pharmazeutische zusammensetzungen aus polypeptidkonjugaten und verfahren zur verwendung davon

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3421303A1 (de)	1984-06-08	1985-12-12	Hoechst Ag, 6230 Frankfurt	Salze aus 3-hydroxy-4-oxo-3,4-dihydro-1,2,3-benzotriazin und amino-verbindungen
US5574008A (en) *	1994-08-30	1996-11-12	Eli Lilly And Company	Biologically active fragments of glucagon-like insulinotropic peptide
US6268343B1 (en) *	1996-08-30	2001-07-31	Novo Nordisk A/S	Derivatives of GLP-1 analogs
BR0010750A (pt)	1999-05-17	2002-02-26	Conjuchem Inc	Peptìdeos insulinotrópicos de longa duração
MXPA02007231A (es) *	2000-01-27	2002-12-09	Lilly Co Eli	Proceso para solubilizar los compuestos de peptido 1 similares a glucagon.
US6969702B2 (en) *	2002-11-20	2005-11-29	Neuronova Ab	Compounds and methods for increasing neurogenesis
BR122019021416A2 (de)	2003-09-19	2019-12-21
US8603972B2 (en) *	2005-03-18	2013-12-10	Novo Nordisk A/S	Extended GLP-1 compounds

2007
- 2007-01-11 BR BRPI0707599-5A patent/BRPI0707599A2/pt not_active Application Discontinuation
- 2007-01-11 DK DK07702683.9T patent/DK1987052T3/da active
- 2007-01-11 KR KR1020087021965A patent/KR101297942B1/ko not_active Expired - Fee Related
- 2007-01-11 IL IL193134A patent/IL193134A/en active IP Right Review Request
- 2007-01-11 US US12/162,562 patent/US8445433B2/en not_active Expired - Fee Related
- 2007-01-11 ES ES07702683T patent/ES2364982T3/es active Active
- 2007-01-11 WO PCT/EP2007/000198 patent/WO2007090496A1/en not_active Ceased
- 2007-01-11 JP JP2008553641A patent/JP5199126B2/ja not_active Expired - Fee Related
- 2007-01-11 MX MX2008010136A patent/MX2008010136A/es not_active Application Discontinuation
- 2007-01-11 AU AU2007214088A patent/AU2007214088B2/en not_active Ceased
- 2007-01-11 PT PT07702683T patent/PT1987052E/pt unknown
- 2007-01-11 DE DE602007014184T patent/DE602007014184D1/de active Active
- 2007-01-11 EP EP07702683A patent/EP1987052B1/de active Active
- 2007-01-11 CN CN2007800046554A patent/CN101379075B/zh not_active Expired - Fee Related
- 2007-01-11 CA CA002641053A patent/CA2641053A1/en not_active Abandoned
- 2007-01-11 AT AT07702683T patent/ATE507235T1/de not_active IP Right Cessation
- 2007-02-05 TW TW096104026A patent/TWI404724B/zh not_active IP Right Cessation
2008
- 2008-07-31 ZA ZA200806690A patent/ZA200806690B/xx unknown
- 2008-08-04 NO NO20083378A patent/NO20083378L/no not_active Application Discontinuation
2013
- 2013-04-29 US US13/872,952 patent/US9040480B2/en active Active

Also Published As

Publication number	Publication date
MX2008010136A (es)	2008-12-19
EP1987052A1 (de)	2008-11-05
TW200745157A (en)	2007-12-16
PT1987052E (pt)	2011-07-25
DK1987052T3 (da)	2011-08-15
AU2007214088B2 (en)	2012-03-22
KR101297942B1 (ko)	2013-08-19
WO2007090496A1 (en)	2007-08-16
ZA200806690B (en)	2009-07-29
US20090292106A1 (en)	2009-11-26
JP2009525997A (ja)	2009-07-16
ES2364982T3 (es)	2011-09-20
ATE507235T1 (de)	2011-05-15
BRPI0707599A2 (pt)	2011-05-10
CN101379075B (zh)	2013-05-15
AU2007214088A1 (en)	2007-08-16
IL193134A (en)	2014-06-30
US9040480B2 (en)	2015-05-26
DE602007014184D1 (de)	2011-06-09
KR20080100448A (ko)	2008-11-18
TWI404724B (zh)	2013-08-11
JP5199126B2 (ja)	2013-05-15
CN101379075A (zh)	2009-03-04
US20130324699A1 (en)	2013-12-05
US8445433B2 (en)	2013-05-21
CA2641053A1 (en)	2007-08-16
EP1987052B1 (de)	2011-04-27
IL193134A0 (en)	2009-02-11

Legal Events

Date	Code	Title	Description
2010-08-23	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO20083378L (no)	2008-10-31	Syntese av glukagon-lignende peptid
MX2010003599A (es)	2010-09-10	Intermediarios y metodos para la sintesis de analogos de halicondrina b.
EA200601795A1 (ru)	2007-04-27	Синтез эфиров бороновой кислоты и кислотных соединений
MX2009008271A (es)	2009-08-12	Procesos e intermediarios para la preparacion de un inhibidor de proteasa macrocilico del vhc.
EA201101015A1 (ru)	2012-02-28	Способ получения бивалирудина
EP2344519A4 (de)	2012-03-14	C-terminale fragmente von glucagon-ähnlichem peptid-1 (glp-1)
EA201170154A1 (ru)	2011-08-30	Производные пиридинопиридинонов, способ их получения и применение в терапии
HRP20080554B1 (hr)	2014-11-21	Postupak priprave inhibitora proteaze hiv
NO20074623L (no)	2007-12-03	Fremgangsmate for peptidsyntese
BRPI0516027A (pt)	2008-08-19	compostos de sulfonamida
TNSN08244A1 (en)	2009-10-30	Process for the preparation of ferri-succinylcasein
EA200970373A1 (ru)	2009-10-30	АНТИДЕПРЕССАНТ, НЕЙРОПРОТЕКТОР, ИНГИБИТОР ОТЛОЖЕНИЙ β-АМИЛОИДА ИЛИ СРЕДСТВО, ЗАМЕДЛЯЮЩЕЕ СТАРЕНИЯ, СОДЕРЖАЩИЕ ГЕТЕРОЦИКЛИЧЕСКОЕ СОЕДИНЕНИЕ КОНКРЕТНОЙ СТРУКТУРЫ
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DK1737889T3 (da)	2011-01-03	Fremgangsmåde til fastfase-peptidsyntese
EP2729157A4 (de)	2015-01-28	Behandlungsverfahren unter verwendung eines pentapeptids aus dem c-terminus des glucagon-like peptids-1 (glp-1)
TW200825088A (en)	2008-06-16	Processes for preparing intermediates of pemetrexed
SV2011003923A (es)	2011-07-28	3-aminociclopentancarboxamidas
GB2482826A (en)	2012-02-15	Synthesis of morphine and related derivatives
CY1112443T1 (el)	2015-12-09	Νεα θεραπευτικη χρηση για τη θεραπεια των λευχαιμιων
MX2009005977A (es)	2009-06-17	Polimorfos de motilida.
WO2007099227A3 (fr)	2007-10-18	Utilisation de la proteine a homeodomaine engrailed comme anxiolytique
IL182575A0 (en)	2007-07-24	On-resin peptide cyclization
NO20074880L (no)	2007-09-25	Proteaseinhibitor forloper syntese
MX2010011055A (es)	2011-02-21	Derivados peptidicos de opiorfina como potentes inhibidores de ectopeptidasas degradadoras de encefalinas.