ATE264870T1 - Verfahren zur lösung von glucagon-ähnlichen peptid-1 (glp-1) verbindungen - Google Patents

Verfahren zur lösung von glucagon-ähnlichen peptid-1 (glp-1) verbindungen

Info

Publication number: ATE264870T1
Authority: AT; Austria
Prior art keywords: glp; solution; compound; compounds; glucagon
Prior art date: 2000-01-27

Application number

AT01904785T

Other languages

English (en)

Inventor

Walter Francis Junior Prouty

Joseph Vincent Junior Rinella

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-01-27

Filing date

2001-01-16

Publication date

2004-05-15

2001-01-16 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

2004-05-15 Application granted granted Critical

2004-05-15 Publication of ATE264870T1 publication Critical patent/ATE264870T1/de

Links

GCYXWQUSHADNBF-AAEALURTSA-N preproglucagon 78-108 Chemical class C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC=1N=CNC=1)[C@@H](C)O)[C@@H](C)O)C(C)C)C1=CC=CC=C1 GCYXWQUSHADNBF-AAEALURTSA-N 0.000 title 1
102100025101 GATA-type zinc finger protein 1 Human genes 0.000 abstract 6
101710198884 GATA-type zinc finger protein 1 Proteins 0.000 abstract 6
-1 GLP-1 compound Chemical class 0.000 abstract 4
DTHNMHAUYICORS-KTKZVXAJSA-N Glucagon-like peptide 1 Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC=1N=CNC=1)[C@@H](C)O)[C@@H](C)O)C(C)C)C1=CC=CC=C1 DTHNMHAUYICORS-KTKZVXAJSA-N 0.000 abstract 3
239000000243 solution Substances 0.000 abstract 3
239000007864 aqueous solution Substances 0.000 abstract 2
239000011260 aqueous acid Substances 0.000 abstract 1
230000006340 racemization Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Health & Medical Sciences (AREA)
Endocrinology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Toxicology (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Analytical Chemistry (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT01904785T 2000-01-27 2001-01-16 Verfahren zur lösung von glucagon-ähnlichen peptid-1 (glp-1) verbindungen ATE264870T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US17843800P	2000-01-27	2000-01-27
US22405800P	2000-08-09	2000-08-09
PCT/US2001/000010 WO2001055213A2 (en)	2000-01-27	2001-01-16	Process for solubilizing glucagon-like peptide 1 (glp-1) compounds

Publications (1)

Publication Number	Publication Date
ATE264870T1 true ATE264870T1 (de)	2004-05-15

Family

ID=26874307

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01904785T ATE264870T1 (de)	2000-01-27	2001-01-16	Verfahren zur lösung von glucagon-ähnlichen peptid-1 (glp-1) verbindungen

Country Status (17)

Country	Link
US (4)	US7598222B2 (de)
EP (1)	EP1257577B1 (de)
JP (1)	JP2003523366A (de)
KR (1)	KR20020073184A (de)
AT (1)	ATE264870T1 (de)
AU (1)	AU2001232735A1 (de)
BR (1)	BR0107837A (de)
CA (1)	CA2396920A1 (de)
DE (1)	DE60102899T2 (de)
DK (1)	DK1257577T3 (de)
ES (1)	ES2218381T3 (de)
HU (1)	HUP0204281A3 (de)
IL (2)	IL150913A0 (de)
MX (1)	MXPA02007231A (de)
PT (1)	PT1257577E (de)
TR (1)	TR200401142T4 (de)
WO (1)	WO2001055213A2 (de)

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2001
- 2001-01-16 AT AT01904785T patent/ATE264870T1/de not_active IP Right Cessation
- 2001-01-16 BR BR0107837-2A patent/BR0107837A/pt not_active IP Right Cessation
- 2001-01-16 PT PT01904785T patent/PT1257577E/pt unknown
- 2001-01-16 TR TR2004/01142T patent/TR200401142T4/xx unknown
- 2001-01-16 KR KR1020027009546A patent/KR20020073184A/ko not_active Ceased
- 2001-01-16 WO PCT/US2001/000010 patent/WO2001055213A2/en not_active Ceased
- 2001-01-16 HU HU0204281A patent/HUP0204281A3/hu not_active Application Discontinuation
- 2001-01-16 DK DK01904785T patent/DK1257577T3/da active
- 2001-01-16 CA CA002396920A patent/CA2396920A1/en not_active Abandoned
- 2001-01-16 MX MXPA02007231A patent/MXPA02007231A/es active IP Right Grant
- 2001-01-16 US US10/169,657 patent/US7598222B2/en not_active Expired - Fee Related
- 2001-01-16 EP EP01904785A patent/EP1257577B1/de not_active Expired - Lifetime
- 2001-01-16 JP JP2001561060A patent/JP2003523366A/ja not_active Withdrawn
- 2001-01-16 IL IL15091301A patent/IL150913A0/xx unknown
- 2001-01-16 DE DE60102899T patent/DE60102899T2/de not_active Expired - Lifetime
- 2001-01-16 AU AU2001232735A patent/AU2001232735A1/en not_active Abandoned
- 2001-01-16 ES ES01904785T patent/ES2218381T3/es not_active Expired - Lifetime
2008
- 2008-02-07 IL IL189371A patent/IL189371A0/en unknown
2009
- 2009-09-01 US US12/551,841 patent/US8222205B2/en not_active Expired - Fee Related
2012
- 2012-04-27 US US13/458,057 patent/US8268780B2/en not_active Expired - Fee Related
- 2012-08-10 US US13/571,443 patent/US8455433B2/en not_active Expired - Fee Related

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Publication number	Publication date
IL189371A0 (en)	2008-06-05
US20120208980A1 (en)	2012-08-16
US20110053838A1 (en)	2011-03-03
US20130072658A1 (en)	2013-03-21
US7598222B2 (en)	2009-10-06
MXPA02007231A (es)	2002-12-09
US20120101034A9 (en)	2012-04-26
US8455433B2 (en)	2013-06-04
ES2218381T3 (es)	2004-11-16
EP1257577A2 (de)	2002-11-20
BR0107837A (pt)	2003-01-14
WO2001055213A2 (en)	2001-08-02
JP2003523366A (ja)	2003-08-05
DE60102899D1 (de)	2004-05-27
EP1257577B1 (de)	2004-04-21
US20030060412A1 (en)	2003-03-27
DE60102899T2 (de)	2005-03-31
WO2001055213A3 (en)	2002-02-28
US8222205B2 (en)	2012-07-17
HUP0204281A3 (en)	2007-03-28
IL150913A0 (en)	2003-02-12
DK1257577T3 (da)	2004-08-02
TR200401142T4 (tr)	2004-07-21
KR20020073184A (ko)	2002-09-19
CA2396920A1 (en)	2001-08-02
AU2001232735A1 (en)	2001-08-07
US8268780B2 (en)	2012-09-18
HUP0204281A2 (hu)	2003-04-28
PT1257577E (pt)	2004-08-31

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