NO20083491L - Metode for fremstilling av sulfonamid-substituerts alkoholer og mellomprodukter for slike - Google Patents
Metode for fremstilling av sulfonamid-substituerts alkoholer og mellomprodukter for slikeInfo
- Publication number
- NO20083491L NO20083491L NO20083491A NO20083491A NO20083491L NO 20083491 L NO20083491 L NO 20083491L NO 20083491 A NO20083491 A NO 20083491A NO 20083491 A NO20083491 A NO 20083491A NO 20083491 L NO20083491 L NO 20083491L
- Authority
- NO
- Norway
- Prior art keywords
- sulfonamide
- preparation
- intermediates
- substituted alcohols
- alcohol compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/08—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with only one hydroxy group and one amino group bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/34—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77445306P | 2006-02-17 | 2006-02-17 | |
| PCT/US2007/004090 WO2007098029A1 (en) | 2006-02-17 | 2007-02-15 | Methods for preparing sulfonamide substituted alcohols and intermediates thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20083491L true NO20083491L (no) | 2008-09-05 |
Family
ID=38180433
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20083491A NO20083491L (no) | 2006-02-17 | 2008-08-12 | Metode for fremstilling av sulfonamid-substituerts alkoholer og mellomprodukter for slike |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US7687666B2 (pt) |
| EP (1) | EP1984321A1 (pt) |
| JP (1) | JP2009528281A (pt) |
| KR (1) | KR20080093126A (pt) |
| CN (1) | CN101415670A (pt) |
| AR (1) | AR059518A1 (pt) |
| AU (1) | AU2007217965A1 (pt) |
| BR (1) | BRPI0707741A2 (pt) |
| CA (1) | CA2641013A1 (pt) |
| CR (1) | CR10156A (pt) |
| EC (1) | ECSP088683A (pt) |
| GT (1) | GT200800155A (pt) |
| IL (1) | IL192931A0 (pt) |
| NO (1) | NO20083491L (pt) |
| PE (1) | PE20080169A1 (pt) |
| RU (1) | RU2008129797A (pt) |
| TW (1) | TW200736195A (pt) |
| WO (1) | WO2007098029A1 (pt) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1289469C (zh) * | 2001-12-20 | 2006-12-13 | 布里斯托尔-迈尔斯斯奎布公司 | α－(N－磺酰氨基)乙酰胺衍生物作为β－淀粉样蛋白抑制剂 |
| BRPI0408962A (pt) * | 2003-03-31 | 2006-04-04 | Wyeth Corp | inibidores sulfonamidas heterocìclicos contendo flúor- e trifluoroalquila da produção de beta amilóide e seus derivados |
| US7838550B2 (en) * | 2006-02-17 | 2010-11-23 | Wyeth Llc | Selective N-sulfonylation of 2-amino fluoro- and trifluoroalkyl substituted alcohols |
| US7550629B2 (en) * | 2006-04-21 | 2009-06-23 | Wyeth | Trifluoromethyl-containing phenylsulfonamide beta amyloid inhibitors |
| US7476762B2 (en) * | 2006-04-21 | 2009-01-13 | Wyeth | Methods for preparing sulfonamide compounds |
| PA8789601A1 (es) * | 2007-07-16 | 2009-02-09 | Wyeth Corp | Proceso para la preparación de trifluoralquil-fenil sulfonamidas y de sulfonamidas heterocíclicas |
| EP2193117A1 (en) * | 2007-07-16 | 2010-06-09 | Wyeth a Corporation of the State of Delaware | Inhibitors of beta amyloid production |
| WO2009012203A1 (en) * | 2007-07-16 | 2009-01-22 | Wyeth | Processes and intermediates for the preparation of heterocyclic sulfonamide compounds |
| US8093276B2 (en) * | 2007-10-31 | 2012-01-10 | Bristol-Myers Squibb Company | Alpha-(N-sulfonamido)acetamide compound as an inhibitor of beta amyloid peptide production |
| US8084477B2 (en) | 2007-10-31 | 2011-12-27 | Bristol-Myers Squibb Company | Alpha-(N-sulfonamido)acetamide compound as an inhibitor of beta amyloid peptide production |
| CL2009000019A1 (es) * | 2008-01-11 | 2009-05-22 | Wyeth Corp | Compuestos derivados de aril sulfonamida que contienen o-sulfato u o-fosfato; procedimiento de preparacion; composicion farmaceutica que los comprende; y uso como profarmacos para incrementar la semivida de circulacion de compuestos inhibidores de la produccion de beta-amiloide, utiles en el tratamiento del alzheimer y cancer. |
| CN102088855A (zh) * | 2008-05-08 | 2011-06-08 | 百时美施贵宝公司 | 2-芳基甘氨酰胺衍生物 |
| US8044077B2 (en) * | 2009-03-19 | 2011-10-25 | Bristol-Myers Squibb Company | Alpha-(N-sulfonamido)acetamide compounds incorporating deuterium as inhibitors of beta amyloid peptide production |
| US7977362B2 (en) * | 2009-03-20 | 2011-07-12 | Bristol-Myers Squibb Company | Alpha-(N-benzenesulfonamido)cycloalkyl derivatives |
| US20110071199A1 (en) * | 2009-03-20 | 2011-03-24 | Bristol-Myers Squibb Company | Thiophenyl Sulfonamides for the Treatment of Alzheimer's Disease |
| US8252821B2 (en) * | 2009-04-14 | 2012-08-28 | Bristol-Myers Squibb Company | Bioavailable capsule compositions of amorphous alpha-(N-sulfonamido)acetamide compound |
| TW201043269A (en) * | 2009-04-14 | 2010-12-16 | Bristol Myers Squibb Co | Bioavailable compositions of amorphous alpha-(N-sulfonamido)acetamide compound |
| EP3615068A1 (en) | 2017-04-28 | 2020-03-04 | Novartis AG | Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor |
| WO2018201056A1 (en) | 2017-04-28 | 2018-11-01 | Novartis Ag | Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor |
| UY38251A (es) | 2018-06-01 | 2019-12-31 | Novartis Ag | Moléculas de unión contra bcma y usos de las mismas |
| KR20220024729A (ko) | 2019-06-24 | 2022-03-03 | 노파르티스 아게 | B-세포 성숙 항원을 표적으로 하는 다중특이성 항체에 대한 투여 요법 및 병용 요법 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1294380B (de) * | 1955-07-21 | 1969-05-08 | E H Karl Dr Dr | Verfahren zur Reduktion von organischen Verbindungen an den C=O-Bindungen mit Metallalkylen als Reduktionsmittel |
| KR100266467B1 (ko) | 1995-09-27 | 2000-10-02 | 우에노 도시오 | 설폰아미드 유도체 |
| JPH09241262A (ja) | 1996-03-08 | 1997-09-16 | Kao Corp | ３−オキサ−２，７−ジアザビシクロ〔３．３．０〕オクタン誘導体 |
| US5962231A (en) | 1997-09-30 | 1999-10-05 | Incyte Pharmaceuticals, Inc. | Human glutathione-S-transferase |
| US6362178B1 (en) | 1997-11-12 | 2002-03-26 | Bayer Aktiengesellschaft | 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors |
| JPH11343279A (ja) | 1998-03-16 | 1999-12-14 | Shionogi & Co Ltd | スルホンアミド誘導体およびそれらを含有するＴＮＦ―α産生抑制剤 |
| GB9805520D0 (en) | 1998-03-17 | 1998-05-13 | Zeneca Ltd | Chemical compounds |
| DE19827640A1 (de) | 1998-06-20 | 1999-12-23 | Bayer Ag | 7-Alkyl- und Cycloalkyl-substituierte Imidazotriazinone |
| IL150022A0 (en) | 1999-12-24 | 2002-12-01 | Bayer Ag | Imidazo [1,3,5] triazinones and the use thereof |
| EP1261609B1 (de) | 1999-12-24 | 2004-11-03 | Bayer HealthCare AG | Triazolotriazinone und ihre verwendung |
| HUP0303857A3 (en) | 2000-12-13 | 2007-07-30 | Wyeth Corp | Heterocyclic sulifonamide inhibitors of beta amyloid production |
| US6657070B2 (en) | 2000-12-13 | 2003-12-02 | Wyeth | Production of chirally pure α-amino acids and N-sulfonyl α-amino acids |
| WO2003050063A2 (en) | 2001-12-11 | 2003-06-19 | Wyeth | PROCESS FOR THE SYNTHESIS OF CHIRALLY PURE β-AMINO-ALCOHOLS |
| TW200307539A (en) | 2002-02-01 | 2003-12-16 | Bristol Myers Squibb Co | Cycloalkyl inhibitors of potassium channel function |
| AU2003212282A1 (en) | 2002-03-11 | 2003-09-22 | Schering Aktiengesellschaft | Cdk inhibiting 2-heteroaryl pyrimidine, the production thereof, and use thereof as a medicament |
| US7288547B2 (en) | 2002-03-11 | 2007-10-30 | Schering Ag | CDK-inhibitory 2-heteroaryl-pyrimidines, their production and use as pharmaceutical agents |
| TW200403058A (en) | 2002-04-19 | 2004-03-01 | Bristol Myers Squibb Co | Heterocyclo inhibitors of potassium channel function |
| JP4530849B2 (ja) * | 2002-06-11 | 2010-08-25 | ワイス・エルエルシー | βアミロイド産生の置換フェニルスルホンアミド阻害剤 |
| WO2004078731A1 (en) | 2003-03-06 | 2004-09-16 | 'chemical Diversity Research Institute', Ltd. | Quinoline-carboxylic acids and the derivatives thereof, a focused library |
| BRPI0408962A (pt) | 2003-03-31 | 2006-04-04 | Wyeth Corp | inibidores sulfonamidas heterocìclicos contendo flúor- e trifluoroalquila da produção de beta amilóide e seus derivados |
| ES2330451T3 (es) | 2004-01-16 | 2009-12-10 | Wyeth | Inhibidores a base de sulfonamidas heterociclicas de la produccion de beta-amiloides que contienen un azol. |
-
2007
- 2007-02-15 PE PE2007000168A patent/PE20080169A1/es not_active Application Discontinuation
- 2007-02-15 BR BRPI0707741-6A patent/BRPI0707741A2/pt not_active IP Right Cessation
- 2007-02-15 AU AU2007217965A patent/AU2007217965A1/en not_active Abandoned
- 2007-02-15 KR KR1020087019836A patent/KR20080093126A/ko not_active Withdrawn
- 2007-02-15 JP JP2008555374A patent/JP2009528281A/ja not_active Withdrawn
- 2007-02-15 TW TW096105699A patent/TW200736195A/zh unknown
- 2007-02-15 CA CA002641013A patent/CA2641013A1/en not_active Abandoned
- 2007-02-15 WO PCT/US2007/004090 patent/WO2007098029A1/en not_active Ceased
- 2007-02-15 AR ARP070100656A patent/AR059518A1/es unknown
- 2007-02-15 RU RU2008129797/04A patent/RU2008129797A/ru not_active Application Discontinuation
- 2007-02-15 US US11/706,636 patent/US7687666B2/en not_active Expired - Fee Related
- 2007-02-15 CN CNA2007800055252A patent/CN101415670A/zh active Pending
- 2007-02-15 EP EP07750892A patent/EP1984321A1/en not_active Withdrawn
-
2008
- 2008-07-17 CR CR10156A patent/CR10156A/es not_active Application Discontinuation
- 2008-07-21 IL IL192931A patent/IL192931A0/en unknown
- 2008-08-12 GT GT200800155A patent/GT200800155A/es unknown
- 2008-08-12 NO NO20083491A patent/NO20083491L/no not_active Application Discontinuation
- 2008-08-15 EC EC2008008683A patent/ECSP088683A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1984321A1 (en) | 2008-10-29 |
| ECSP088683A (es) | 2008-09-29 |
| IL192931A0 (en) | 2009-02-11 |
| AR059518A1 (es) | 2008-04-09 |
| AU2007217965A1 (en) | 2007-08-30 |
| RU2008129797A (ru) | 2010-03-27 |
| TW200736195A (en) | 2007-10-01 |
| PE20080169A1 (es) | 2008-04-11 |
| US7687666B2 (en) | 2010-03-30 |
| CN101415670A (zh) | 2009-04-22 |
| GT200800155A (es) | 2009-02-20 |
| CA2641013A1 (en) | 2007-08-30 |
| CR10156A (es) | 2008-10-03 |
| BRPI0707741A2 (pt) | 2011-05-10 |
| WO2007098029A1 (en) | 2007-08-30 |
| KR20080093126A (ko) | 2008-10-20 |
| US20070197830A1 (en) | 2007-08-23 |
| JP2009528281A (ja) | 2009-08-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |