NO20083583L - Heterosykliske antivirale forbindelser - Google Patents

Heterosykliske antivirale forbindelser

Info

Publication number
NO20083583L
NO20083583L NO20083583A NO20083583A NO20083583L NO 20083583 L NO20083583 L NO 20083583L NO 20083583 A NO20083583 A NO 20083583A NO 20083583 A NO20083583 A NO 20083583A NO 20083583 L NO20083583 L NO 20083583L
Authority
NO
Norway
Prior art keywords
compounds
antagonists
formula
treatment
invention further
Prior art date
Application number
NO20083583A
Other languages
English (en)
Inventor
Chris Richard Melville
Remy Lemoine
Fernando Padilla
David Mark Rotstein
Jutta Wanner
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38024288&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20083583(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20083583L publication Critical patent/NO20083583L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Kjemokinreseptor-antagonister, spesielt 3,7-diazabicyklo[3.3.0]oktan-forbindelser med formel (I), hvor R1-R3 R6c og X1 er som definert her, er antagonister av kjemokin-CCR5-reseptorer, som er anvendelige for behandling eller forebygging av en infeksjon med humant immunsviktvirus (HIV-infeksjon), eller behandling av AIDS eller ARC. Oppfinnelsen tilveiebringer videre metoder for behandling av sykdommer som blir lindret av CCR5-antagonister. Oppfinnelsen omfatter farmasøytiske preparater og metoder for anvendelse av forbindelsene for behandling av disse sykdommene. Oppfinnelsen omfatter videre fremgangsmåter for fremstilling av forbindelser med formel I.
NO20083583A 2006-02-15 2008-08-19 Heterosykliske antivirale forbindelser NO20083583L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77398406P 2006-02-15 2006-02-15
PCT/EP2007/051063 WO2007093515A1 (en) 2006-02-15 2007-02-05 Heterocyclic antiviral compounds

Publications (1)

Publication Number Publication Date
NO20083583L true NO20083583L (no) 2008-10-27

Family

ID=38024288

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20083583A NO20083583L (no) 2006-02-15 2008-08-19 Heterosykliske antivirale forbindelser

Country Status (16)

Country Link
US (1) US20070191406A1 (no)
EP (1) EP1987035A1 (no)
JP (1) JP2009526802A (no)
KR (1) KR20080102386A (no)
CN (1) CN101384599A (no)
AR (1) AR059490A1 (no)
AU (1) AU2007214602A1 (no)
BR (1) BRPI0707923A2 (no)
CA (1) CA2641382A1 (no)
CL (1) CL2007000380A1 (no)
IL (1) IL193108A0 (no)
NO (1) NO20083583L (no)
RU (1) RU2008136763A (no)
TW (1) TW200804388A (no)
WO (1) WO2007093515A1 (no)
ZA (1) ZA200806845B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2662835A1 (en) 2006-09-18 2008-03-27 Remy Lemoine Octahydropyrrolo [3, 4-c] pyrrole derivatives and their use as antiviral agents
US8464207B2 (en) * 2007-10-12 2013-06-11 Novell Intellectual Property Holdings, Inc. System and method for tracking software changes
US8772277B2 (en) 2011-08-04 2014-07-08 Takeda Pharmaceutical Company Limited Nitrogen-containing heterocyclic compound
CN102718695B (zh) * 2012-06-25 2014-04-02 华东师范大学 一种氮杂双环[3.3.0]辛烷衍生物的合成方法
CN106103446B (zh) * 2014-03-26 2019-07-30 豪夫迈·罗氏有限公司 作为自分泌运动因子(atx)和溶血磷脂酸(lpa)生产抑制剂的二环化合物
CA2992889A1 (en) 2015-09-04 2017-03-09 F. Hoffmann-La Roche Ag Phenoxymethyl derivatives
WO2018167113A1 (en) 2017-03-16 2018-09-20 F. Hoffmann-La Roche Ag New bicyclic compounds as atx inhibitors
WO2022194122A1 (zh) * 2021-03-16 2022-09-22 上海翰森生物医药科技有限公司 含氮杂环的多环化合物及其制备方法和应用
CN113861045B (zh) * 2021-10-25 2024-06-07 绍兴众昌化工股份有限公司 一种(r)-3-氨基丁醇的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2006146608A (ru) * 2004-06-09 2008-07-20 Ф.Хоффманн-Ля Рош Аг (Ch) ОКТАГИДРОПИРРОЛО[3,4-с]-ПРОИЗВОДНЫЕ И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ПРОТИВОВИРУСНЫХ АГЕНТОВ
RU2008136756A (ru) * 2006-02-15 2010-03-20 Ф.Хоффманн-Ля Рош Аг (Ch) Гетеробициклические противовирусные соединения

Also Published As

Publication number Publication date
BRPI0707923A2 (pt) 2011-05-17
CN101384599A (zh) 2009-03-11
RU2008136763A (ru) 2010-03-20
JP2009526802A (ja) 2009-07-23
IL193108A0 (en) 2009-02-11
CA2641382A1 (en) 2007-08-23
WO2007093515A1 (en) 2007-08-23
AU2007214602A1 (en) 2007-08-23
TW200804388A (en) 2008-01-16
KR20080102386A (ko) 2008-11-25
CL2007000380A1 (es) 2008-01-11
ZA200806845B (en) 2009-11-25
US20070191406A1 (en) 2007-08-16
AR059490A1 (es) 2008-04-09
EP1987035A1 (en) 2008-11-05

Similar Documents

Publication Publication Date Title
NO20083585L (no) Hetero-bisykliske antivirale forbindelser
NO20070137L (no) Heterocykliske antivirale forbindelser
NO20083583L (no) Heterosykliske antivirale forbindelser
NO20082135L (no) HIV integrase inhibitorer
EP2041159B8 (en) Macrocyclic compounds as antiviral agents
TW200621762A (en) Novel compounds
TW200600503A (en) Bicyclic heterocycles as hiv integrase inhibitors
WO2009146555A8 (en) Hiv integrase inhibitors from pyridoxine
NO20071246L (no) Kinazolinonderivater og deres anvendelse som B-RAF-inhibitorer.
NO20081935L (no) HIV-integraseinhibitorer
NO20070199L (no) Substituerte kinazoloner som anti-kreftmidler
NO20080797L (no) Bicykliske heterocykler som HIV Integrase inhibitorer
NO20065443L (no) HIV-Integraseinhibitorer: Sykliske pyrimidinonforbindelser
EA200801909A1 (ru) Соединения пиридина для лечения заболеваний, опосредованных действием простагландина
NO20052739L (no) CCR5-antagonister som medikamenter
NO20092689L (no) Quinuclidinolderivater som muskarin reseptorantagonister
NO20072784L (no) Pyridenkarboksamidderivater for anvendelse som anticancer midler
WO2008002959A3 (en) Hiv integrase inhibitors
NO20081844L (no) Terapeutiske forbindelser
NO20084049L (no) Forbindelser med forsterket ampa receptor og anvendelse derav i medisin
NO20092342L (no) Azaspiroderivativater
NO20060195L (no) Kinolylamidderivater som CCR-5-antagonister
MXPA04005209A (es) Antagonistas del receptor de adenosina a2a.
MY134223A (en) Tropane derivatives as ccr5 modulators
TW200519112A (en) Tropane derivatives