NO20070137L - Heterocykliske antivirale forbindelser - Google Patents

Heterocykliske antivirale forbindelser

Info

Publication number
NO20070137L
NO20070137L NO20070137A NO20070137A NO20070137L NO 20070137 L NO20070137 L NO 20070137L NO 20070137 A NO20070137 A NO 20070137A NO 20070137 A NO20070137 A NO 20070137A NO 20070137 L NO20070137 L NO 20070137L
Authority
NO
Norway
Prior art keywords
compounds
treating
antagonists
invention further
diseases
Prior art date
Application number
NO20070137A
Other languages
English (en)
Inventor
David Marc Rotstein
Eun Kyung Lee
Chris Richard Melville
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20070137L publication Critical patent/NO20070137L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Kjemokinreseptorantagonister, spesielt 3,7-diazabisyklo[3.3.0]oktanforbindelser med følgende formel: er antagonister av kjemokin CCR5-reseptorer som er anvendelige for behandling eller forhindring av en human immunsvikt-virus (HIV) infeksjon eller behandling av AIDS eller ARC. Oppfinnelsen tilveiebringer videre metoder for behandling av sykdommer som blir lindret med CCR5-antagonister. Oppfinnelsen omfatter farmasøytiske preparater og metoder for anvendelse av forbindelsene for behandling av disse sykdommer. Oppfinnelsen omfatter videre prosesser for fremstilling av nevnte forbindelser.
NO20070137A 2004-06-09 2007-01-08 Heterocykliske antivirale forbindelser NO20070137L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57875904P 2004-06-09 2004-06-09
PCT/EP2005/005895 WO2005121145A2 (en) 2004-06-09 2005-06-01 Octahydro-pyrrolo[3,4-c] derivatives and their use as antiviral compounds

Publications (1)

Publication Number Publication Date
NO20070137L true NO20070137L (no) 2007-03-06

Family

ID=35431500

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20070137A NO20070137L (no) 2004-06-09 2007-01-08 Heterocykliske antivirale forbindelser

Country Status (21)

Country Link
US (2) US7164019B2 (no)
EP (1) EP1761542B1 (no)
JP (1) JP2008501743A (no)
CN (1) CN101001860A (no)
AR (1) AR049209A1 (no)
AT (1) ATE382623T1 (no)
AU (1) AU2005251891A1 (no)
BR (1) BRPI0511982A (no)
CA (1) CA2569910A1 (no)
DE (1) DE602005004144T2 (no)
DK (1) DK1761542T3 (no)
ES (1) ES2297727T3 (no)
IL (1) IL179534A0 (no)
MX (1) MXPA06014404A (no)
NO (1) NO20070137L (no)
PL (1) PL1761542T3 (no)
PT (1) PT1761542E (no)
RU (1) RU2006146608A (no)
TW (1) TW200701981A (no)
WO (1) WO2005121145A2 (no)
ZA (1) ZA200609837B (no)

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GB0724251D0 (en) 2007-12-12 2008-02-06 Univ Edinburgh Therapeutic compounds and their use
GB0804685D0 (en) 2008-03-13 2008-04-16 Univ Edinburgh Therapeutic compounds and their use
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JO3579B1 (ar) 2014-09-26 2020-07-05 Luc Therapeutics Inc مُعدِلات تفاغرية سالبة لمستقبل nr2b من المركب n-ألكيل أريل-5-أوكسي أريل-ثامن هيدرو-خماسي الحلقة [c] بيرول
MA41898A (fr) 2015-04-10 2018-02-13 Hoffmann La Roche Dérivés de quinazolinone bicyclique
MX387736B (es) 2015-09-04 2025-03-18 Hoffmann La Roche Derivados de fenoximetilo.
CN107635995B (zh) 2015-09-24 2022-08-19 豪夫迈·罗氏有限公司 作为atx抑制剂的二环化合物
PE20180451A1 (es) 2015-09-24 2018-03-05 Hoffmann La Roche Nuevos compuestos biciclicos como inhibidores de atx
KR20180054634A (ko) 2015-09-24 2018-05-24 에프. 호프만-라 로슈 아게 이중 오토탁신(atx)/탄산 무수화효소(ca) 억제제로서 신규한 이환형 화합물
MX2017015034A (es) 2015-09-24 2018-04-13 Hoffmann La Roche Nuevos compuestos biciclicos como inhibidores duales de autotaxina (atx)/anhidrasa carbonica (ca).
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Also Published As

Publication number Publication date
PL1761542T3 (pl) 2008-06-30
ES2297727T3 (es) 2008-05-01
US7164019B2 (en) 2007-01-16
WO2005121145A3 (en) 2006-03-02
US7714018B2 (en) 2010-05-11
MXPA06014404A (es) 2007-02-19
US20070117859A1 (en) 2007-05-24
CN101001860A (zh) 2007-07-18
EP1761542A2 (en) 2007-03-14
RU2006146608A (ru) 2008-07-20
DE602005004144T2 (de) 2009-01-29
WO2005121145A2 (en) 2005-12-22
CA2569910A1 (en) 2005-12-22
TW200701981A (en) 2007-01-16
IL179534A0 (en) 2007-05-15
DE602005004144D1 (de) 2008-02-14
US20060014767A1 (en) 2006-01-19
PT1761542E (pt) 2008-03-26
ATE382623T1 (de) 2008-01-15
ZA200609837B (en) 2008-09-25
EP1761542B1 (en) 2008-01-02
BRPI0511982A (pt) 2008-01-22
AR049209A1 (es) 2006-07-05
JP2008501743A (ja) 2008-01-24
AU2005251891A1 (en) 2005-12-22
DK1761542T3 (da) 2008-04-28

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