NO20083585L - Hetero-bisykliske antivirale forbindelser - Google Patents

Hetero-bisykliske antivirale forbindelser

Info

Publication number
NO20083585L
NO20083585L NO20083585A NO20083585A NO20083585L NO 20083585 L NO20083585 L NO 20083585L NO 20083585 A NO20083585 A NO 20083585A NO 20083585 A NO20083585 A NO 20083585A NO 20083585 L NO20083585 L NO 20083585L
Authority
NO
Norway
Prior art keywords
antagonists
ccr5
hetero
cyclic
antiviral compounds
Prior art date
Application number
NO20083585A
Other languages
English (en)
Inventor
Chris Richard Melville
Remy Lemoine
David Mark Rotstein
Jutta Wanner
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20083585L publication Critical patent/NO20083585L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Kjemokinreseptor-antagonister, spesielt 3,7-diazabicyklo[3.3.0]oktan-forbindelser med formel (I), hvor R1-R3 R6c og X1 er som definert her, er antagonister av kjemokin-CCR5-reseptorer og er anvendelige for behandling eller forebygging av en infeksjon med humant immunsviktvirus (HIV-1-infeksjon) eller behandling av AIDS eller ARC. Oppfinnelsen tilveiebringer videre metoder for behandling av sykdommer som lindres av CCR5-antagonister. Oppfinnelsen omfatter farmasøytiske preparater og metoder for anvendelse av forbindelsene for behandling av sykdommer som er mediert av CCR5-reseptoren.
NO20083585A 2006-02-15 2008-08-19 Hetero-bisykliske antivirale forbindelser NO20083585L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77394206P 2006-02-15 2006-02-15
PCT/EP2007/051099 WO2007093520A1 (en) 2006-02-15 2007-02-06 Hetero-bycyclic antiviral compounds

Publications (1)

Publication Number Publication Date
NO20083585L true NO20083585L (no) 2008-10-28

Family

ID=38157829

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20083585A NO20083585L (no) 2006-02-15 2008-08-19 Hetero-bisykliske antivirale forbindelser

Country Status (16)

Country Link
US (1) US20070191335A1 (no)
EP (1) EP1987036A1 (no)
JP (1) JP2009526803A (no)
KR (1) KR20080102387A (no)
CN (1) CN101384596A (no)
AR (1) AR059571A1 (no)
AU (1) AU2007216543A1 (no)
BR (1) BRPI0710474A2 (no)
CA (1) CA2641389A1 (no)
CL (1) CL2007000362A1 (no)
IL (1) IL193107A0 (no)
NO (1) NO20083585L (no)
RU (1) RU2008136756A (no)
TW (1) TW200801010A (no)
WO (1) WO2007093520A1 (no)
ZA (1) ZA200806756B (no)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2641382A1 (en) * 2006-02-15 2007-08-23 F. Hoffmann-La Roche Ag Heterocyclic antiviral compounds
CA2662835A1 (en) 2006-09-18 2008-03-27 Remy Lemoine Octahydropyrrolo [3, 4-c] pyrrole derivatives and their use as antiviral agents
CA2669917A1 (en) * 2006-11-17 2008-05-22 Dawn M. George Aminopyrrolidines as chemokine receptor antagonists
US8464207B2 (en) * 2007-10-12 2013-06-11 Novell Intellectual Property Holdings, Inc. System and method for tracking software changes
DE102010025663A1 (de) * 2010-06-30 2012-01-05 Karl-Heinz Glüsenkamp Neue beta-Aminoaldehyd-Derivate, Verfahren zu ihrer Herstellung und ihre chemische Verwendung als reaktive Intermediate
BR112014011534A2 (pt) 2011-11-14 2017-05-09 Basf Se composto, composição, uso de um composto e método para controle de vegetação indesejada
JP2015519314A (ja) 2012-04-27 2015-07-09 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ 置換型ｎ−（テトラゾール−５−イル）−およびｎ−（トリアゾール−５−イル）ピリジン−３−イル−カルボキサミド化合物ならびに除草剤としてのそれらの使用
JP6141408B2 (ja) 2012-04-27 2017-06-07 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ 置換型ｎ−（テトラゾール−５−イル）−およびｎ−（トリアゾール−５−イル）アリールカルボキサミド化合物ならびに除草剤としてのそれらの使用
CN102718695B (zh) * 2012-06-25 2014-04-02 华东师范大学 一种氮杂双环[3.3.0]辛烷衍生物的合成方法
AR092211A1 (es) * 2012-09-24 2015-04-08 Merck Patent Ges Mit Beschränkter Haftung Derivados de hidropirrolopirrol
BR112015028597A2 (pt) 2013-05-15 2017-07-25 Basf Se n-(tetrazol-5-il)- e n-(5-triazol-il)arilcarboxamidas, composição, utilização de um composto e método para o controle da vegetação
WO2014184058A1 (en) 2013-05-15 2014-11-20 Basf Se Substituted 1,2,5-oxadiazole compounds and their use as herbicides
WO2015007564A1 (en) 2013-07-18 2015-01-22 Basf Se Substituted n-(1,2,4-triazol-3-yl)arylcarboxamide compounds and their use as herbicides
WO2015052178A1 (en) 2013-10-10 2015-04-16 Basf Se 1,2,5-oxadiazole compounds and their use as herbicides
BR112016007065A2 (pt) 2013-10-10 2017-08-01 Basf Se composto, composição, utilização de um composto e método para o controle da vegetação
WO2015052173A1 (en) 2013-10-10 2015-04-16 Basf Se Tetrazole and triazole compounds and their use as herbicides
EP2907807A1 (en) 2014-02-18 2015-08-19 Basf Se Benzamide compounds and their use as herbicides
CA3006838A1 (en) 2015-12-17 2017-06-22 Basf Se Benzamide compounds and their use as herbicides
EP3484876A1 (en) 2016-07-14 2019-05-22 Pfizer Inc Novel pyrimidine carboxamides as inhibitors of vanin-1 enzyme
EP3630735B1 (en) 2017-05-30 2021-05-05 Basf Se Benzamide compounds and their use as herbicides
US20200157086A1 (en) 2017-05-30 2020-05-21 Basf Se Benzamide compounds and their use as herbicides
AR112112A1 (es) 2017-06-20 2019-09-18 Basf Se Compuestos de benzamida y su uso como herbicidas
WO2019016385A1 (en) 2017-07-21 2019-01-24 Basf Se BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES
AR114040A1 (es) 2017-12-22 2020-07-15 Basf Se Compuestos de benzamida y su uso como herbicidas
WO2019162309A1 (en) 2018-02-21 2019-08-29 Basf Se Benzamide compounds and their use as herbicides
WO2019162308A1 (en) 2018-02-21 2019-08-29 Basf Se Benzamide compounds and their use as herbicides

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2006146608A (ru) * 2004-06-09 2008-07-20 Ф.Хоффманн-Ля Рош Аг (Ch) ОКТАГИДРОПИРРОЛО[3,4-с]-ПРОИЗВОДНЫЕ И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ПРОТИВОВИРУСНЫХ АГЕНТОВ

Also Published As

Publication number Publication date
CA2641389A1 (en) 2007-08-23
US20070191335A1 (en) 2007-08-16
AU2007216543A1 (en) 2007-08-23
CN101384596A (zh) 2009-03-11
CL2007000362A1 (es) 2008-01-11
IL193107A0 (en) 2009-02-11
KR20080102387A (ko) 2008-11-25
BRPI0710474A2 (pt) 2011-08-16
RU2008136756A (ru) 2010-03-20
JP2009526803A (ja) 2009-07-23
TW200801010A (en) 2008-01-01
WO2007093520A1 (en) 2007-08-23
ZA200806756B (en) 2009-11-25
AR059571A1 (es) 2008-04-16
EP1987036A1 (en) 2008-11-05

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