NO20083584L - Bensoyl-piperidin derivater som 5HT2/D3 modulatorer - Google Patents

Bensoyl-piperidin derivater som 5HT2/D3 modulatorer

Info

Publication number
NO20083584L
NO20083584L NO20083584A NO20083584A NO20083584L NO 20083584 L NO20083584 L NO 20083584L NO 20083584 A NO20083584 A NO 20083584A NO 20083584 A NO20083584 A NO 20083584A NO 20083584 L NO20083584 L NO 20083584L
Authority
NO
Norway
Prior art keywords
modulators
benzoyl
piperidine derivatives
ht2a
compounds
Prior art date
Application number
NO20083584A
Other languages
English (en)
Norwegian (no)
Inventor
Luca Claudio Gobbi
Thomas Luebbers
Olivier Roche
Georg Jaeschke
Rosa Maria Rodriguez Sarmiento
Lucinda Steward
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38091740&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20083584(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20083584L publication Critical patent/NO20083584L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
NO20083584A 2006-02-17 2008-08-19 Bensoyl-piperidin derivater som 5HT2/D3 modulatorer NO20083584L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06110112 2006-02-17
EP06112464 2006-04-11
PCT/EP2007/051160 WO2007093540A1 (en) 2006-02-17 2007-02-07 Benzoyl-piperidine derivatives as 5ht2/d3 modulators

Publications (1)

Publication Number Publication Date
NO20083584L true NO20083584L (no) 2008-11-14

Family

ID=38091740

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20083584A NO20083584L (no) 2006-02-17 2008-08-19 Bensoyl-piperidin derivater som 5HT2/D3 modulatorer

Country Status (15)

Country Link
US (2) US8039490B2 (pt)
EP (1) EP1987019B1 (pt)
JP (1) JP4855485B2 (pt)
KR (1) KR101062513B1 (pt)
AR (1) AR059513A1 (pt)
AU (1) AU2007216563B2 (pt)
BR (1) BRPI0707960A2 (pt)
CA (1) CA2640807A1 (pt)
CL (1) CL2007000396A1 (pt)
ES (1) ES2399447T3 (pt)
IL (1) IL193176A (pt)
NO (1) NO20083584L (pt)
RU (1) RU2396265C2 (pt)
TW (1) TWI329107B (pt)
WO (1) WO2007093540A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009013212A2 (en) 2007-07-26 2009-01-29 F. Hoffmann-La Roche Ag Dual modulators of 5-ht2a and d3 receptors
WO2009019174A1 (en) * 2007-08-09 2009-02-12 F. Hoffmann-La Roche Ag Benzoyl-piperidine derivatives as dual modulators of the 5-ht2a and d3 receptors
CN102159557A (zh) 2008-09-22 2011-08-17 弗·哈夫曼-拉罗切有限公司 哌嗪d3和5-ht2a受体调节剂
US8586579B2 (en) 2010-06-21 2013-11-19 Hoffmann-La Roche Inc. Anellated pyridine compounds
US8470828B2 (en) 2010-07-06 2013-06-25 Hoffmann-La Roche Inc. Anellated pyridine compounds
PE20140913A1 (es) * 2010-11-15 2014-08-22 Abbvie Inc Inhibidores de nampt y rock
US8877778B2 (en) 2010-12-15 2014-11-04 Hoffmann-La Roche Inc. Benzofurane compounds
US8722683B2 (en) 2011-02-17 2014-05-13 Hoffmann La-Roche Inc. Benzodioxole piperazine compounds
US8598357B2 (en) 2011-03-03 2013-12-03 Hoffmann-La Roche Inc. Benzodioxole piperidine compounds
US8921397B2 (en) * 2011-05-04 2014-12-30 Hoffmann-La Roche Inc. Benzofurane-piperidine compounds
KR20180017013A (ko) 2015-05-06 2018-02-20 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 K-Ras 조절제
CN110785414A (zh) 2017-04-20 2020-02-11 加利福尼亚大学董事会 K-Ras调节剂
JP6948830B2 (ja) * 2017-05-17 2021-10-13 花王株式会社 乳化化粧料
WO2019014100A1 (en) 2017-07-10 2019-01-17 Celgene Corporation ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF
EP4053110A4 (en) * 2019-10-29 2023-12-06 Shanghai Hansoh Biomedical Co., Ltd. FOUR-MEMBED RING DERIVATIVE MODIFIER, METHOD FOR PRODUCING THEREOF AND ITS USE
WO2021088920A1 (zh) 2019-11-05 2021-05-14 上海翰森生物医药科技有限公司 苯并噻吩类衍生物调节剂、其制备方法和应用
WO2021164661A1 (zh) * 2020-02-20 2021-08-26 上海科技大学 2-苯基环丙基甲基胺衍生物及其制备方法和用途
US20240254109A1 (en) 2021-04-28 2024-08-01 Shanghai Hansoh Biomedical Co., Ltd. Salt containing piperazine polycyclic derivative, crystal form thereof, preparation method therefor, and use thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4024264A (en) * 1974-08-15 1977-05-17 Ab Ferrosan Diphenylbutylpiperidines
GB1514718A (en) 1974-08-15 1978-06-21 Ferrosan Ab Diphenyl-butylpiperidines
JP2860689B2 (ja) 1990-03-14 1999-02-24 第一製薬株式会社 ピリミジン誘導体
EP0479601B1 (en) * 1990-10-05 1999-12-15 Ajinomoto Co., Inc. Piperidine derivatives and their use as antiarrhythmic agents
KR20010108394A (ko) * 1999-03-26 2001-12-07 다비드 에 질레스 신규 화합물
GB0117577D0 (en) * 2001-02-16 2001-09-12 Aventis Pharm Prod Inc Novel heterocyclic substituted carbonyl derivatives and their use as dopamine D receptor ligands
HUP0103986A2 (hu) 2001-09-28 2003-06-28 Richter Gedeon Vegyészeti Gyár Rt. Új karbonsavamid szerkezetet tartalmazó piperidinil vegyületek, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
DK1499607T3 (da) * 2001-12-04 2006-04-18 Actelion Pharmaceuticals Ltd 4-(piperidyl- og pyrrolidyl-alkyl-ureido)-quinoliner som urotensin II-receptorantagonister
EP1348434A1 (en) * 2002-03-27 2003-10-01 Fujisawa Deutschland GmbH Use of pyridyl amides as inhibitors of angiogenesis
TWI263497B (en) * 2002-03-29 2006-10-11 Lilly Co Eli Pyridinoylpiperidines as 5-HT1F agonists
US6770659B2 (en) * 2002-08-26 2004-08-03 Sk Corporation Benzoyl piperidine compounds
US7186725B2 (en) 2003-01-03 2007-03-06 Genzyme Corporation Anti-inflammatory compositions and methods
WO2009013212A2 (en) * 2007-07-26 2009-01-29 F. Hoffmann-La Roche Ag Dual modulators of 5-ht2a and d3 receptors
WO2009019174A1 (en) * 2007-08-09 2009-02-12 F. Hoffmann-La Roche Ag Benzoyl-piperidine derivatives as dual modulators of the 5-ht2a and d3 receptors

Also Published As

Publication number Publication date
EP1987019A1 (en) 2008-11-05
US20120004208A1 (en) 2012-01-05
WO2007093540A1 (en) 2007-08-23
KR101062513B1 (ko) 2011-09-06
KR20080095899A (ko) 2008-10-29
IL193176A0 (en) 2009-02-11
US20070197531A1 (en) 2007-08-23
CL2007000396A1 (es) 2008-01-04
RU2396265C2 (ru) 2010-08-10
AU2007216563B2 (en) 2012-08-09
AR059513A1 (es) 2008-04-09
ES2399447T3 (es) 2013-04-01
IL193176A (en) 2013-01-31
TWI329107B (en) 2010-08-21
JP2009526807A (ja) 2009-07-23
AU2007216563A1 (en) 2007-08-23
CA2640807A1 (en) 2007-08-23
TW200808758A (en) 2008-02-16
JP4855485B2 (ja) 2012-01-18
EP1987019B1 (en) 2012-11-28
US8039490B2 (en) 2011-10-18
RU2008133322A (ru) 2010-03-27
US8415350B2 (en) 2013-04-09
BRPI0707960A2 (pt) 2011-05-10

Similar Documents

Publication Publication Date Title
NO20083584L (no) Bensoyl-piperidin derivater som 5HT2/D3 modulatorer
NO20084783L (no) Syntese av acylaminoalkenylenamider nyttige som substans P antagonister
EA200702470A1 (ru) Производные пиррола в качестве положительных аллостерических модуляторов метаботропных глутаматных рецепторов
ATE463495T1 (de) Oxadiazolylpyrazolopyrimidine als mglur2- antagonisten
MX2009003316A (es) Derivados de pirazina-2-carboxamida como moduladores receptores de cb2.
IL189191A0 (en) Thiazolyl piperidine derivatives useful as h3 receptor modulators
NO20093200L (no) Tiazolidinderivater
NO20076479L (no) Nye oksadiazolderivater og anvendelse derav som positive allosteriske metabotropiske modulatorer av glutamatreseptorer
AU2008303600A8 (en) 1,1,1-trifluoro-2-hydroxy-3-phenylpropane derivatives
ATE524466T1 (de) 3-azabicycloä3.3.0üoktanverbindungen
NO20076478L (no) Substituerte oksadiazolderivater som positive allosteriske modulatorer av metabotrope glutamatreseptorer
NO20060195L (no) Kinolylamidderivater som CCR-5-antagonister
NO20082096L (no) Azaindol-2-karboksamidderivativer
ATE493397T1 (de) Neuartige tetrazolderivate als positive allosterische modulatoren von metabotropen glutamatrezeptoren
NO20071922L (no) Indazoler, benzisokazoler og benzinsotiazoler og anvendelse derav som ostrogene midler
NO20090779L (no) 5,6-bisaryl-2-pyridin-karboksamidderivater, fremstilling og anvendelse derav i terapeutika som uretosin II receptorantagonister
MX2010004272A (es) Derivados de tetrazol como moduladores de receptores de glutamato metabotropicos (mglurs).
MY156324A (en) 2-methyl-1-(phenylsulfonyl)-4-(piperazin-1-yl)-1h-benzimidazole as 5-hydroxytryptamine-6 ligands
NO20090282L (no) Syklopropylaminderivater som histamin H3 reseptormodulatorer
MX2009004947A (es) Arilsulfonil-pirrolidinas como inhibidores 5-hidroxitriptaminas6 (5-ht6).
NO20074047L (no) Ny fremgangsmate for fremstilling av substituerte indoler
NO20082214L (no) 1,1-Diokso-tiomorfolinyl-indolyl-metanonderivater for anvendelse som H3-modulatorer
MY146671A (en) Tetrahydronaphthaline derivatives, methods for the production and use thereof as anti-inflammatory agents
NO20065733L (no) Naftalinderivater nyttige som histamin-3-reseptor ligander
EA200700365A1 (ru) Производные индол-2-карбоксамидина как антагонисты nmda рецептора

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application