NO20084542L - Farmasoytisk kombinasjon inneholdende 3-(3-dimetylamino-1-etyl-2-metyl-propyl)-fenol og paracetamol - Google Patents
Farmasoytisk kombinasjon inneholdende 3-(3-dimetylamino-1-etyl-2-metyl-propyl)-fenol og paracetamolInfo
- Publication number
- NO20084542L NO20084542L NO20084542A NO20084542A NO20084542L NO 20084542 L NO20084542 L NO 20084542L NO 20084542 A NO20084542 A NO 20084542A NO 20084542 A NO20084542 A NO 20084542A NO 20084542 L NO20084542 L NO 20084542L
- Authority
- NO
- Norway
- Prior art keywords
- paracetamol
- dimethylamino
- phenol
- propyl
- ethyl
- Prior art date
Links
- KWTWDQCKEHXFFR-UHFFFAOYSA-N 3-[1-(dimethylamino)-2-methylpentan-3-yl]phenol Chemical compound CN(C)CC(C)C(CC)C1=CC=CC(O)=C1 KWTWDQCKEHXFFR-UHFFFAOYSA-N 0.000 title abstract 2
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 title abstract 2
- 229960005489 paracetamol Drugs 0.000 title abstract 2
- 208000002193 Pain Diseases 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 2
- 208000000094 Chronic Pain Diseases 0.000 abstract 1
- 208000005298 acute pain Diseases 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000037361 pathway Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Det er beskrevet en kombinasjon omfattende som komponenter (a) forbindelsen 3-(3dimetylamino-1-etyl-2-metyl-propyl)-fenol og (b) paracetamol eller et derivat derav, et farmasøytisk preparat og en doseringsform omfattende nevnte kombinasjon så vel som en fremgangsmåte for behandling av smerte, for eksempel kronisk eller akutt smerte, kjennetegnet ved at komponenter (a) og (b) administreres samtidig eller trinnvis til et pattedyr, hvori komponent (a) kan administreres før eller komponent (b) og hvori komponentene (a) eller (b) administreres til pattedyret enten via samme eller forskjellig administrasjonsvei.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06008851 | 2006-04-28 | ||
| PCT/EP2007/003632 WO2007128413A1 (en) | 2006-04-28 | 2007-04-25 | Pharmaceutical combination comprising 3- ( 3-dimethylamino-1-ethyl-2-methyl-propyl) -phenol and paracetamol |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20084542L true NO20084542L (no) | 2008-10-28 |
| NO341602B1 NO341602B1 (no) | 2017-12-11 |
Family
ID=37025148
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20084542A NO341602B1 (no) | 2006-04-28 | 2008-10-28 | Farmasøytisk kombinasjon omfattende 3-(3-dimetylamino-1-etyl-2-metyl-propyl)-fenol og paracetamol |
| NO20171831A NO343505B1 (no) | 2006-04-28 | 2017-11-17 | Farmasøytisk kombinasjon omfattende 3-(3-dimetylamino-1-etyl-2-metylpropyl)-fenyl og paracetamol |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20171831A NO343505B1 (no) | 2006-04-28 | 2017-11-17 | Farmasøytisk kombinasjon omfattende 3-(3-dimetylamino-1-etyl-2-metylpropyl)-fenyl og paracetamol |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP2012764B1 (no) |
| JP (2) | JP5496653B2 (no) |
| KR (1) | KR101396166B1 (no) |
| CN (1) | CN101431990B (no) |
| AT (1) | ATE494889T1 (no) |
| AU (1) | AU2007247481B2 (no) |
| BR (1) | BRPI0710682B8 (no) |
| CA (1) | CA2650423C (no) |
| CY (1) | CY1111369T1 (no) |
| DE (1) | DE602007011913D1 (no) |
| DK (1) | DK2012764T3 (no) |
| EC (2) | ECSP088793A (no) |
| ES (1) | ES2356093T3 (no) |
| HR (1) | HRP20110076T1 (no) |
| IL (1) | IL194883A (no) |
| MX (1) | MX2008013779A (no) |
| NO (2) | NO341602B1 (no) |
| NZ (1) | NZ571442A (no) |
| PL (1) | PL2012764T3 (no) |
| PT (1) | PT2012764E (no) |
| RU (1) | RU2442576C2 (no) |
| SI (1) | SI2012764T1 (no) |
| WO (1) | WO2007128413A1 (no) |
| ZA (1) | ZA200810124B (no) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102007012165A1 (de) * | 2007-03-12 | 2008-09-18 | Grünenthal GmbH | Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie des Neuropathieschmerzes |
| CN102908339A (zh) * | 2007-11-23 | 2013-02-06 | 格吕伦塔尔有限公司 | 他喷他多组合物 |
| SI2582366T1 (sl) | 2010-06-15 | 2016-02-29 | Gruenenthal Gmbh | Farmacevtska kombinacija za zdravljenje bolečine |
| CA2828635C (en) * | 2011-03-04 | 2020-01-14 | Grunenthal Gmbh | Parenteral administration of tapentadol |
| RS56692B1 (sr) | 2011-03-04 | 2018-03-30 | Gruenenthal Gmbh | Polučvrsta vodena farmaceutska kompozicija koja sadrži tapentadol |
| KR101946790B1 (ko) | 2011-03-04 | 2019-02-13 | 그뤼넨탈 게엠베하 | 경구 투여를 위한 타펜타돌의 수성 약제학적 제형 |
| US9320729B2 (en) | 2012-05-18 | 2016-04-26 | Gruenenthal Gmbh | Pharmaceutical composition comprising (1r,4r)-6′-flouro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a propionic acid derivative |
| US20130310385A1 (en) | 2012-05-18 | 2013-11-21 | Gruenenthal Gmbh | Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine and Antidepressants |
| US20130310435A1 (en) * | 2012-05-18 | 2013-11-21 | Gruenenthal Gmbh | Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N, N-dimethyl-4-phenyl-4,9' -dihydro-3'H-spiro[cyclohexane-1,1' -pyrano[3,4,b]indol]-4-amine and Paracetamol or Propacetamol |
| US9855286B2 (en) | 2012-05-18 | 2018-01-02 | Gruenenthal Gmbh | Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-di methyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a salicylic acid component |
| EP2808319A1 (en) | 2013-05-31 | 2014-12-03 | Arevipharma GmbH | 3-[3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol resin complex |
| EP3273953B1 (en) | 2015-03-27 | 2019-01-02 | Grünenthal GmbH | Stable formulation for parenteral administration of tapentadol |
| CN109996533A (zh) | 2016-09-23 | 2019-07-09 | 格吕伦塔尔有限公司 | 用于肠胃外施用他喷他多的稳定制剂 |
| WO2018153947A1 (en) | 2017-02-23 | 2018-08-30 | Grünenthal GmbH | Tapentadol as local anesthetic |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4426245A1 (de) * | 1994-07-23 | 1996-02-22 | Gruenenthal Gmbh | 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung |
| PE20030527A1 (es) * | 2001-10-24 | 2003-07-26 | Gruenenthal Chemie | Formulacion farmaceutica con liberacion retardada que contiene 3-(3-dimetilamino-1-etil-2-metil-propil) fenol o una sal farmaceuticamente aceptable del mismo y tabletas para administracion oral que la contienen |
| PT1562567T (pt) * | 2002-11-22 | 2017-08-24 | Gruenenthal Gmbh | Combinação de analgésicos selecionados e inibidores da cox-ii |
-
2007
- 2007-04-25 RU RU2008146816/15A patent/RU2442576C2/ru active
- 2007-04-25 WO PCT/EP2007/003632 patent/WO2007128413A1/en not_active Ceased
- 2007-04-25 KR KR1020087028929A patent/KR101396166B1/ko not_active Expired - Fee Related
- 2007-04-25 EP EP07724562A patent/EP2012764B1/en active Active
- 2007-04-25 AT AT07724562T patent/ATE494889T1/de active
- 2007-04-25 CA CA2650423A patent/CA2650423C/en active Active
- 2007-04-25 PL PL07724562T patent/PL2012764T3/pl unknown
- 2007-04-25 SI SI200730498T patent/SI2012764T1/sl unknown
- 2007-04-25 BR BRPI0710682A patent/BRPI0710682B8/pt active IP Right Grant
- 2007-04-25 DE DE602007011913T patent/DE602007011913D1/de active Active
- 2007-04-25 NZ NZ571442A patent/NZ571442A/en not_active IP Right Cessation
- 2007-04-25 DK DK07724562.9T patent/DK2012764T3/da active
- 2007-04-25 MX MX2008013779A patent/MX2008013779A/es active IP Right Grant
- 2007-04-25 ES ES07724562T patent/ES2356093T3/es active Active
- 2007-04-25 CN CN2007800148115A patent/CN101431990B/zh not_active Expired - Fee Related
- 2007-04-25 HR HR20110076T patent/HRP20110076T1/hr unknown
- 2007-04-25 PT PT07724562T patent/PT2012764E/pt unknown
- 2007-04-25 AU AU2007247481A patent/AU2007247481B2/en not_active Ceased
- 2007-04-25 JP JP2009506978A patent/JP5496653B2/ja not_active Expired - Fee Related
-
2008
- 2008-10-06 EC EC2008008793A patent/ECSP088793A/es unknown
- 2008-10-23 IL IL194883A patent/IL194883A/en active IP Right Grant
- 2008-10-28 NO NO20084542A patent/NO341602B1/no unknown
- 2008-11-27 ZA ZA200810124A patent/ZA200810124B/xx unknown
-
2011
- 2011-04-05 CY CY20111100353T patent/CY1111369T1/el unknown
-
2013
- 2013-07-11 JP JP2013145481A patent/JP2013213045A/ja not_active Withdrawn
-
2017
- 2017-01-05 EC ECIEPI2017643A patent/ECSP17000643A/es unknown
- 2017-11-17 NO NO20171831A patent/NO343505B1/no unknown
Also Published As
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