NO20090079L - Arylsulfonamider med analgesisk virkning - Google Patents

Arylsulfonamider med analgesisk virkning

Info

Publication number
NO20090079L
NO20090079L NO20090079A NO20090079A NO20090079L NO 20090079 L NO20090079 L NO 20090079L NO 20090079 A NO20090079 A NO 20090079A NO 20090079 A NO20090079 A NO 20090079A NO 20090079 L NO20090079 L NO 20090079L
Authority
NO
Norway
Prior art keywords
arylsulfonamides
analgesic effect
analgesic
effect
Prior art date
Application number
NO20090079A
Other languages
English (en)
Inventor
Norbert Hauel
Ingo Konetzki
Annette Maria Schuler-Metz
Iris Kauffmann-Hefner
Rainer Walter
Henri Doods
Heiner Ebel
Angelo Ceci
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of NO20090079L publication Critical patent/NO20090079L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/04—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with only hydrogen atoms, halogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Indole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrrole Compounds (AREA)
  • Peptides Or Proteins (AREA)
NO20090079A 2006-08-19 2009-01-07 Arylsulfonamider med analgesisk virkning NO20090079L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102006039003A DE102006039003A1 (de) 2006-08-19 2006-08-19 Neue Verbindungen
PCT/EP2007/058408 WO2008022945A1 (de) 2006-08-19 2007-08-14 Arylsulfonamide mit analgetischer wirkung

Publications (1)

Publication Number Publication Date
NO20090079L true NO20090079L (no) 2009-02-16

Family

ID=38925625

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20090079A NO20090079L (no) 2006-08-19 2009-01-07 Arylsulfonamider med analgesisk virkning
NO20091025A NO20091025L (no) 2006-08-19 2009-03-09 Arylsulfonamider med analgesisk virkning

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20091025A NO20091025L (no) 2006-08-19 2009-03-09 Arylsulfonamider med analgesisk virkning

Country Status (20)

Country Link
US (2) US7858618B2 (no)
EP (3) EP2061779B1 (no)
JP (3) JP5291623B2 (no)
KR (1) KR20090047535A (no)
CN (1) CN101516867A (no)
AR (1) AR062426A1 (no)
AU (1) AU2007287652A1 (no)
BR (1) BRPI0715645A2 (no)
CA (1) CA2663598A1 (no)
CL (1) CL2007002407A1 (no)
CO (1) CO6160230A2 (no)
DE (1) DE102006039003A1 (no)
EA (1) EA200900279A1 (no)
IL (1) IL197021A0 (no)
MX (1) MX2009001791A (no)
NO (2) NO20090079L (no)
SG (3) SG169338A1 (no)
TW (1) TW200815394A (no)
WO (1) WO2008022945A1 (no)
ZA (1) ZA200810782B (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
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DE102006039003A1 (de) 2006-08-19 2008-02-21 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Verbindungen
DE102007034620A1 (de) * 2007-07-25 2009-01-29 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue B1-Antagonisten
WO2010017850A1 (de) * 2008-08-12 2010-02-18 Boehringer Ingelheim International Gmbh Verfahren zur herstellung von cycloalkyl-substituierten piperazinverbindungen
EP2025675A1 (de) 2007-08-14 2009-02-18 Boehringer Ingelheim International GmbH Arylsulfonamide mit analgetischer Wirkung
US20110046106A1 (en) * 2008-02-06 2011-02-24 Boehringer Ingelheim International Gmbh Aryl sulfonamides as effective analgesics
RU2503674C2 (ru) * 2008-04-08 2014-01-10 Грюненталь Гмбх Замещенные производные сульфонамида
EP2300466B1 (en) 2008-06-20 2014-08-06 Bristol-Myers Squibb Company Imidazopyridine and imidazopyrazine compounds useful as kinase inhibitors
US20110124626A1 (en) * 2008-07-18 2011-05-26 Takeda Pharmaceutical Company Limited Benzazepine derivatives and their use as histamine h3 antagonists
US8207335B2 (en) * 2009-02-13 2012-06-26 Boehringer Ingelheim International Gmbh Process for making certain compounds having B1 antagonistic activity
AU2011302295B2 (en) 2010-09-13 2015-08-20 Microbiotix, Inc. Inhibitors of viral entry into mammalian cells
WO2014009319A1 (en) 2012-07-11 2014-01-16 Boehringer Ingelheim International Gmbh Indolinone derivatives anticancer compounds
KR101735705B1 (ko) 2015-09-22 2017-05-15 주식회사 에코시안 건물 에너지 효율화 평가 방법 및 장치
CN105153168A (zh) * 2015-09-29 2015-12-16 上海天慈国际药业有限公司 N-[4-(2-甲基-4,5-二氢-3H-咪唑并[4,5-d][1]苯并氮杂卓-6-甲酰基)苯基]-2-苯基苯甲酰胺盐酸盐的制备方法
KR101645157B1 (ko) 2015-11-10 2016-08-02 주식회사 넥스미디어 통합 음식 제공 서비스 방법 및 장치
RU2764243C2 (ru) 2017-09-22 2022-01-14 ДЖУБИЛАНТ ЭПИПЭД ЭлЭлСи Гетероциклические соединения в качестве ингибиторов PAD
CN111225915B (zh) 2017-10-18 2023-03-07 朱比兰特埃皮帕德有限公司 作为pad抑制剂的咪唑并吡啶化合物
US11629135B2 (en) 2017-11-06 2023-04-18 Jubilant Prodell Llc Pyrimidine derivatives as inhibitors of PD1/PD-L1 activation
RS65576B1 (sr) 2017-11-24 2024-06-28 Jubilant Episcribe Llc Heterociklična jedinjenja kao inhibitori prmt5
CN112105610B (zh) 2018-03-13 2024-01-26 朱比连特普罗德尔有限责任公司 作为pd1/pd-l1相互作用/活化的抑制剂的双环化合物

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DE1100635B (de) 1958-04-22 1961-03-02 Rhone Poulenc Sa Verfahren zur Herstellung von Phenthiazinderivaten
EP0173552B1 (en) 1984-08-24 1991-10-09 The Upjohn Company Recombinant dna compounds and the expression of polypeptides such as tpa
IL115420A0 (en) * 1994-09-26 1995-12-31 Zeneca Ltd Aminoheterocyclic derivatives
WO2001037826A1 (en) 1999-11-26 2001-05-31 Shionogi & Co., Ltd. Npyy5 antagonists
FR2819254B1 (fr) 2001-01-08 2003-04-18 Fournier Lab Sa Nouveaux composes de la n-(phenylsulfonyl) glycine, leur procede de preparation et leur utilisation pour obtenir des compostions pharmaceutiques
FR2840897B1 (fr) * 2002-06-14 2004-09-10 Fournier Lab Sa Nouveaux derives d'arylsulfonamides et leur utilisation en therapeutique
CA2509881A1 (en) 2002-12-19 2004-07-08 Elan Pharmaceuticals, Inc. Substituted n-phenyl sulfonamide bradykinin antagonists
WO2004087700A1 (fr) * 2003-03-25 2004-10-14 Laboratoires Fournier S.A. Derives du benzenesulfonamide, leur procede de preparation et leur utilisation de la douleur
US7557197B2 (en) * 2004-01-28 2009-07-07 Oregon Health & Science University Human soluble neuropilin-1 primary polyadenylation signal and uses thereof
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JP2008514546A (ja) 2004-09-30 2008-05-08 大正製薬株式会社 ピリジン誘導体及びその使用に関連する治療法
DE102005013967A1 (de) 2004-11-05 2006-10-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Bradykinin-B1-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
US20060217362A1 (en) 2004-12-29 2006-09-28 Tung Jay S Novel compounds useful for bradykinin B1 receptor antagonism
DE102006039003A1 (de) 2006-08-19 2008-02-21 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Verbindungen
CA2687931C (en) 2007-05-31 2016-05-24 Boehringer Ingelheim International Gmbh Ccr2 receptor antagonists and uses thereof
DE102007034620A1 (de) * 2007-07-25 2009-01-29 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue B1-Antagonisten
JP2011505334A (ja) * 2007-08-14 2011-02-24 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規化合物
EP2188269B1 (de) * 2007-08-14 2014-05-07 Boehringer Ingelheim International GmbH Arylsulfonamide mit analgetischer wirkung
DE102007046887A1 (de) * 2007-09-28 2009-04-09 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung von (1R,5S)-Anhydroecgoninestersalzen

Also Published As

Publication number Publication date
CL2007002407A1 (es) 2009-03-27
AR062426A1 (es) 2008-11-05
NO20091025L (no) 2009-03-09
CN101516867A (zh) 2009-08-26
CA2663598A1 (en) 2008-02-28
JP2010501514A (ja) 2010-01-21
AU2007287652A1 (en) 2008-02-28
IL197021A0 (en) 2009-11-18
JP5650781B2 (ja) 2015-01-07
EA200900279A1 (ru) 2009-10-30
SG169339A1 (en) 2011-03-30
US8252785B2 (en) 2012-08-28
SG169338A1 (en) 2011-03-30
SG169337A1 (en) 2011-03-30
CO6160230A2 (es) 2010-05-20
JP5529202B2 (ja) 2014-06-25
US20110021488A1 (en) 2011-01-27
WO2008022945A1 (de) 2008-02-28
EP2284166A1 (de) 2011-02-16
EP2402329A1 (de) 2012-01-04
JP5291623B2 (ja) 2013-09-18
JP2012149086A (ja) 2012-08-09
EP2061779A1 (de) 2009-05-27
EP2061779B1 (de) 2013-11-06
BRPI0715645A2 (pt) 2013-07-09
US20090137545A1 (en) 2009-05-28
EP2284166B1 (de) 2013-10-16
ZA200810782B (en) 2009-11-25
TW200815394A (en) 2008-04-01
JP2013177392A (ja) 2013-09-09
US7858618B2 (en) 2010-12-28
DE102006039003A1 (de) 2008-02-21
MX2009001791A (es) 2009-03-02
KR20090047535A (ko) 2009-05-12
EP2402329B1 (de) 2013-05-22

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