NO20091949L - Sammensetninger og fremgangsmater for modulering av C-kit og PDGFR-reseptorer - Google Patents
Sammensetninger og fremgangsmater for modulering av C-kit og PDGFR-reseptorerInfo
- Publication number
- NO20091949L NO20091949L NO20091949A NO20091949A NO20091949L NO 20091949 L NO20091949 L NO 20091949L NO 20091949 A NO20091949 A NO 20091949A NO 20091949 A NO20091949 A NO 20091949A NO 20091949 L NO20091949 L NO 20091949L
- Authority
- NO
- Norway
- Prior art keywords
- methods
- raf
- compounds
- kit
- abl
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Ophthalmology & Optometry (AREA)
- Molecular Biology (AREA)
- Psychology (AREA)
- Endocrinology (AREA)
- AIDS & HIV (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86243006P | 2006-10-20 | 2006-10-20 | |
| PCT/US2007/081538 WO2008051757A1 (en) | 2006-10-20 | 2007-10-16 | Compositions and methods for modulating c-kit and pdgfr receptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20091949L true NO20091949L (no) | 2009-05-19 |
Family
ID=39027274
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20091949A NO20091949L (no) | 2006-10-20 | 2009-05-19 | Sammensetninger og fremgangsmater for modulering av C-kit og PDGFR-reseptorer |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US7678792B2 (es) |
| EP (1) | EP2076513A1 (es) |
| JP (1) | JP2010506948A (es) |
| KR (1) | KR101079520B1 (es) |
| CN (1) | CN101528744A (es) |
| AR (1) | AR063343A1 (es) |
| AU (1) | AU2007309279B2 (es) |
| BR (1) | BRPI0718162A2 (es) |
| CA (1) | CA2667010A1 (es) |
| CL (1) | CL2007003005A1 (es) |
| CO (1) | CO6170361A2 (es) |
| CR (1) | CR10717A (es) |
| EA (1) | EA200900573A1 (es) |
| EC (1) | ECSP099353A (es) |
| IL (1) | IL197875A0 (es) |
| MA (1) | MA30888B1 (es) |
| MX (1) | MX2009004141A (es) |
| NI (1) | NI200900061A (es) |
| NO (1) | NO20091949L (es) |
| PE (1) | PE20081262A1 (es) |
| SM (1) | SMP200900027B (es) |
| TN (1) | TN2009000145A1 (es) |
| TW (1) | TW200825081A (es) |
| WO (1) | WO2008051757A1 (es) |
| ZA (1) | ZA200902711B (es) |
Families Citing this family (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1483283A4 (en) | 2002-03-13 | 2007-04-11 | Signum Biosciences Inc | MODULATION OF PROTEIN METHYLATION AND PHOSPHOPROTEIN PHOSPHATE |
| US7923041B2 (en) | 2005-02-03 | 2011-04-12 | Signum Biosciences, Inc. | Compositions and methods for enhancing cognitive function |
| CA2601777A1 (en) | 2005-02-03 | 2006-08-10 | Signum Biosciences, Inc. | Compositions and methods for enhancing cognitive function |
| US8188113B2 (en) * | 2006-09-14 | 2012-05-29 | Deciphera Pharmaceuticals, Inc. | Dihydropyridopyrimidinyl, dihydronaphthyidinyl and related compounds useful as kinase inhibitors for the treatment of proliferative diseases |
| US7897762B2 (en) | 2006-09-14 | 2011-03-01 | Deciphera Pharmaceuticals, Llc | Kinase inhibitors useful for the treatment of proliferative diseases |
| WO2008067127A2 (en) | 2006-11-09 | 2008-06-05 | Alcon Research, Ltd. | Water insoluble polymer matrix for drug delivery |
| TWI498115B (zh) * | 2007-12-27 | 2015-09-01 | Daiichi Sankyo Co Ltd | 咪唑羰基化合物 |
| EA018551B1 (ru) | 2008-02-22 | 2013-08-30 | Айрм Ллк | ГЕТЕРОЦИКЛИЧЕСКИЕ СОЕДИНЕНИЯ И СОДЕРЖАЩИЕ ИХ КОМПОЗИЦИИ В КАЧЕСТВЕ ИНГИБИТОРОВ КИНАЗ c-KIT И PDGFR |
| AU2009239430B2 (en) | 2008-04-21 | 2015-01-22 | Signum Biosciences, Inc. | Compounds, compositions and methods for making the same |
| FR2930552B1 (fr) * | 2008-04-24 | 2012-10-12 | Centre Nat Rech Scient | N-acylthiourees et n-acylurees inhibiteurs de la voie de signalisation des proteines hedgehog |
| CN102089278A (zh) * | 2008-06-11 | 2011-06-08 | Irm责任有限公司 | 用于治疗疟疾的化合物和组合物 |
| US20110200597A1 (en) * | 2008-08-05 | 2011-08-18 | George Mason Intellectual Properties, Inc. | Signal pathway alterations and drug target elevations in primary metachronous metastatic colorectal cancer compared to non-metastatic disease |
| JP5444365B2 (ja) * | 2008-10-29 | 2014-03-19 | デシフェラ ファーマシューティカルズ,エルエルシー | 抗癌活性および抗増殖活性を示すシクロプロパンアミドおよび類似物質 |
| AR074776A1 (es) * | 2008-12-18 | 2011-02-09 | Sanofi Aventis | Metodo para tratar la degeneracion macular; modulando el sistema inmunitario del paciente |
| WO2010071846A2 (en) | 2008-12-19 | 2010-06-24 | Afraxis, Inc. | Compounds for treating neuropsychiatric conditions |
| SG173610A1 (en) * | 2009-02-13 | 2011-09-29 | Fovea Pharmaceuticals Sa | [1, 2, 4] triazolo [1, 5 -a] pyridines as kinase inhibitors |
| US8372970B2 (en) | 2009-10-09 | 2013-02-12 | Afraxis, Inc. | 8-ethyl-6-(aryl)pyrido[2,3-D]pyrimidin-7(8H)-ones for the treatment of CNS disorders |
| PH12012501535A1 (en) | 2010-01-29 | 2012-10-22 | Boehringer Ingelheim Int | Substituted naphthyridines and their use as syk kinase inhibitors |
| US9181238B2 (en) | 2010-02-05 | 2015-11-10 | Novartis Ag | N-(pyridin-2-yl)sulfonamides and compositions thereof as protein kinase inhibitors |
| US9540443B2 (en) * | 2011-01-26 | 2017-01-10 | Kolltan Pharmaceuticals, Inc. | Anti-kit antibodies |
| PL2701510T3 (pl) * | 2011-04-25 | 2017-07-31 | Usher Iii Initiative Inc | Pirazolopirydazyny oraz sposoby leczenia zwyrodnieniowych chorób siatkówki i utraty słuchu związanych z zespołem ushera |
| KR101986484B1 (ko) | 2011-07-26 | 2019-06-10 | 베링거 인겔하임 인터내셔날 게엠베하 | 치환된 퀴놀린 및 이의 약제로서의 용도 |
| JP2014528412A (ja) * | 2011-09-30 | 2014-10-27 | キネタ・インコーポレイテツド | 抗ウイルス化合物 |
| WO2013171642A1 (en) | 2012-05-15 | 2013-11-21 | Novartis Ag | Benzamide derivatives for inhibiting the activity of abl1, abl2 and bcr-abl1 |
| CA2870339C (en) | 2012-05-15 | 2020-06-02 | Novartis Ag | Compounds and compositions for inhibiting the activity of abl1, abl2 and bcr-abl1 |
| CN104379574B (zh) | 2012-05-15 | 2017-03-01 | 诺华股份有限公司 | 用于抑制abl1、abl2和bcr‑abl1的活性的苯甲酰胺衍生物 |
| PE20161416A1 (es) | 2012-05-15 | 2017-01-08 | Novartis Ag | Derivados de benzamida para la inhibicion de la actividad abl1, abl2 y bcr-abl1 |
| US8461179B1 (en) | 2012-06-07 | 2013-06-11 | Deciphera Pharmaceuticals, Llc | Dihydronaphthyridines and related compounds useful as kinase inhibitors for the treatment of proliferative diseases |
| SI3366293T1 (sl) * | 2012-06-07 | 2020-08-31 | Deciphera Pharmaceuticals, Llc | Dihidronafthiridini in sorodne spojine uporabne kot kinazni inhibitorji za zdravljenje proliferativnih bolezni |
| NZ630363A (en) | 2012-07-25 | 2018-09-28 | Celldex Therapeutics Inc | Anti-kit antibodies and uses thereof |
| US9227976B2 (en) | 2012-10-25 | 2016-01-05 | Usher Iii Initiative, Inc. | Pyrazolopyridazines and methods for treating retinal-degenerative diseases and hearing loss associated with usher syndrome |
| WO2014210159A1 (en) * | 2013-06-26 | 2014-12-31 | Proteostasis Therapeutics, Inc. | Methods of modulating cftr activity |
| GB201401886D0 (en) | 2014-02-04 | 2014-03-19 | Lytix Biopharma As | Neurodegenerative therapies |
| CA2942386A1 (en) | 2014-03-13 | 2015-09-17 | Proteostasis Therapeutics, Inc. | Compounds, compositions, and methods for increasing cftr activity |
| WO2015138934A1 (en) | 2014-03-13 | 2015-09-17 | Proteostasis Therapeutics, Inc. | Compounds, compositions, and methods for increasing cftr activity |
| CN113975386A (zh) | 2014-05-23 | 2022-01-28 | 塞尔德克斯医疗公司 | 嗜酸性粒细胞或肥大细胞相关病症的治疗 |
| CA2952862A1 (en) | 2014-06-19 | 2015-12-23 | Proteostasis Therapeutics, Inc. | Compounds, compositions and methods of increasing cftr activity |
| CN105085489B (zh) | 2014-11-05 | 2019-03-01 | 益方生物科技(上海)有限公司 | 嘧啶或吡啶类化合物、其制备方法和医药用途 |
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| AU2001292320A1 (en) | 2000-10-02 | 2002-04-15 | Tanabe Seiyaku Co., Ltd. | Benzylamine compound, process for producing the same, and intermediate therefor |
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| AU2005325676A1 (en) * | 2004-12-23 | 2006-08-03 | Deciphera Pharmaceuticals, Llc | Anti-inflammatory medicaments |
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| US8188113B2 (en) * | 2006-09-14 | 2012-05-29 | Deciphera Pharmaceuticals, Inc. | Dihydropyridopyrimidinyl, dihydronaphthyidinyl and related compounds useful as kinase inhibitors for the treatment of proliferative diseases |
| WO2008058126A2 (en) * | 2006-11-06 | 2008-05-15 | Supergen, Inc. | Imidazo[1,2-b]pyridazine and pyrazolo[1,5-a]pyrimidine derivatives and their use as protein kinase inhibitors |
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| AU2007309279B2 (en) | 2011-03-24 |
| ECSP099353A (es) | 2009-06-30 |
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| PE20081262A1 (es) | 2008-10-29 |
| WO2008051757A1 (en) | 2008-05-02 |
| SMAP200900027A (it) | 2009-07-14 |
| CA2667010A1 (en) | 2008-05-02 |
| CR10717A (es) | 2009-07-02 |
| KR101079520B1 (ko) | 2011-11-03 |
| NI200900061A (es) | 2010-03-10 |
| SMP200900027B (it) | 2010-01-19 |
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| AU2007309279A1 (en) | 2008-05-02 |
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| US20100081656A1 (en) | 2010-04-01 |
| ZA200902711B (en) | 2010-05-26 |
| IL197875A0 (en) | 2009-12-24 |
| US20080176846A1 (en) | 2008-07-24 |
| EA200900573A1 (ru) | 2009-10-30 |
| EP2076513A1 (en) | 2009-07-08 |
| US8106068B2 (en) | 2012-01-31 |
| BRPI0718162A2 (pt) | 2013-11-26 |
| US7678792B2 (en) | 2010-03-16 |
| JP2010506948A (ja) | 2010-03-04 |
| AR063343A1 (es) | 2009-01-21 |
| MA30888B1 (fr) | 2009-11-02 |
| KR20090054477A (ko) | 2009-05-29 |
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