NO20092714L - Fremgangsmate ved induksjon av terminal differensiering - Google Patents

Fremgangsmate ved induksjon av terminal differensiering

Info

Publication number
NO20092714L
NO20092714L NO20092714A NO20092714A NO20092714L NO 20092714 L NO20092714 L NO 20092714L NO 20092714 A NO20092714 A NO 20092714A NO 20092714 A NO20092714 A NO 20092714A NO 20092714 L NO20092714 L NO 20092714L
Authority
NO
Norway
Prior art keywords
induction
terminal differentiation
saha
hydrate
pharmaceutically acceptable
Prior art date
Application number
NO20092714A
Other languages
English (en)
Other versions
NO332749B1 (no
Inventor
Judy H Chiao
Victoria M Richon
Thomas A Miller
W Kevin Kelly
Original Assignee
Sloan Kettering Inst Cancer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27805074&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20092714(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Publication of NO20092714L publication Critical patent/NO20092714L/no
Application filed by Sloan Kettering Inst Cancer filed Critical Sloan Kettering Inst Cancer
Publication of NO332749B1 publication Critical patent/NO332749B1/no

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    • A61K9/4866Organic macromolecular compounds
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    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/164Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
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    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
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    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
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    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

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  • Dermatology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Hospice & Palliative Care (AREA)
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Abstract

Anvendelse av suberoylanilid hydroksaminsyre (SAHA) representert av den følgende struktur: eller et farmasøytisk akseptabelt salt derav eller hydrat derav, for fremstilling av et oralt medikament til behandling av kreft i en pasient, hvor SAHA eller det farmasøytisk akseptable salt eller hydrat derav er oralt.
NO20092714A 2002-03-04 2009-07-20 Anvendelse av suberoylanilidhydroksaminsyre for fremstilling av et oralt medikament til behandling av kreft NO332749B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36175902P 2002-03-04 2002-03-04
PCT/US2003/006451 WO2003075839A2 (en) 2002-03-04 2003-03-04 Methods of inducing terminal differentiation

Publications (2)

Publication Number Publication Date
NO20092714L true NO20092714L (no) 2004-10-11
NO332749B1 NO332749B1 (no) 2013-01-07

Family

ID=27805074

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20044112A NO329984B1 (no) 2002-03-04 2004-09-28 Sammensetning omfattende krystallinsk suberoylanilid hydroksaminsyre (SAHA) samt fremgangsmate for fremstilling derav
NO20092714A NO332749B1 (no) 2002-03-04 2009-07-20 Anvendelse av suberoylanilidhydroksaminsyre for fremstilling av et oralt medikament til behandling av kreft

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO20044112A NO329984B1 (no) 2002-03-04 2004-09-28 Sammensetning omfattende krystallinsk suberoylanilid hydroksaminsyre (SAHA) samt fremgangsmate for fremstilling derav

Country Status (17)

Country Link
US (7) US20040072735A1 (no)
EP (4) EP1487426B1 (no)
JP (4) JP4732693B2 (no)
KR (2) KR100868813B1 (no)
CN (3) CN1720034A (no)
AU (1) AU2003213684C1 (no)
BR (1) BR0308250A (no)
CA (3) CA2632078C (no)
ES (1) ES2532607T3 (no)
IL (3) IL163909A0 (no)
MX (1) MXPA04008577A (no)
NO (2) NO329984B1 (no)
NZ (3) NZ550185A (no)
PL (1) PL372239A1 (no)
RU (3) RU2320331C2 (no)
WO (1) WO2003075839A2 (no)
ZA (2) ZA200407942B (no)

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WO2003032921A2 (en) * 2001-10-16 2003-04-24 Sloan-Kettering Institute For Cancer Research Treatment of neurodegenerative diseases and cancer of the brain
EP1482962A4 (en) * 2002-02-15 2009-12-23 Sloan Kettering Inst Cancer METHOD FOR THE TREATMENT OF TRX-MEDIATED ILLNESSES
US7148257B2 (en) * 2002-03-04 2006-12-12 Merck Hdac Research, Llc Methods of treating mesothelioma with suberoylanilide hydroxamic acid
US20070060614A1 (en) * 2002-03-04 2007-03-15 Bacopoulos Nicholas G Methods of treating cancer with hdac inhibitors
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US20060276547A1 (en) * 2002-03-04 2006-12-07 Bacopoulos Nicholas G Methods of treating cancer with HDAC inhibitors
NZ550185A (en) * 2002-03-04 2008-10-31 Merck Hdac Res Llc Methods of inducing terminal differentiation Methods of inducing terminal differentiation
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TW559390U (en) * 2002-08-27 2003-10-21 Molex Inc Electrical connector
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FR2847817B1 (fr) * 2002-11-28 2006-11-10 Centre Nat Rech Scient Utilisation d'un inhibiteur d'histone deacetylase pour le traitement des dystrophies musculaires
KR20050122210A (ko) 2003-03-17 2005-12-28 다케다 샌디에고, 인코포레이티드 히스톤 탈아세틸화 효소 억제제
JP2006523693A (ja) * 2003-04-01 2006-10-19 メモリアル スローン−ケタリング キャンサー センター ヒドロキサム酸化合物およびその使用方法
WO2005012256A1 (en) 2003-07-22 2005-02-10 Astex Therapeutics Limited 3, 4-disubstituted 1h-pyrazole compounds and their use as cyclin dependent kinases (cdk) and glycogen synthase kinase-3 (gsk-3) modulators
KR20050022216A (ko) * 2003-08-25 2005-03-07 윤덕구 동결건조 즉석소면 및 그 제조방법
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MXPA04008577A (es) 2005-07-13
NZ550185A (en) 2008-10-31
CN101259120A (zh) 2008-09-10
EP2322160A1 (en) 2011-05-18
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CA2478094C (en) 2010-11-23
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