NO20100580L - Fremgangsmater for behandling av reumatoid artritt ved anvendelse av opploselig mutant CTLA4 molekyl - Google Patents

Fremgangsmater for behandling av reumatoid artritt ved anvendelse av opploselig mutant CTLA4 molekyl

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Publication number
NO20100580L
NO20100580L NO20100580A NO20100580A NO20100580L NO 20100580 L NO20100580 L NO 20100580L NO 20100580 A NO20100580 A NO 20100580A NO 20100580 A NO20100580 A NO 20100580A NO 20100580 L NO20100580 L NO 20100580L
Authority
NO
Norway
Prior art keywords
methods
rheumatoid arthritis
soluble ctla4
treating rheumatoid
mutant molecule
Prior art date
Application number
NO20100580A
Other languages
English (en)
Inventor
Robert J Peach
Robert Cohen
Suzette Carr
David Hagerty
Jean-Claude Becker
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22804919&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20100580(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Publication of NO20100580L publication Critical patent/NO20100580L/no
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61P35/02—Antineoplastic agents specific for leukemia
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    • A—HUMAN NECESSITIES
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    • A61P37/02—Immunomodulators
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    • A61P37/02—Immunomodulators
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70521—CD28, CD152
    • A—HUMAN NECESSITIES
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    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
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  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)

Abstract

Den foreliggende oppfinnelsen angår sammensetninger og fremgangsmåter for behandling av revmatisk sykdom, ved å administrere til et individ løselige CTLA4-molekyler som blokkerer endogene B7-molekyler fra å binde deres ligander.
NO20100580A 2000-07-03 2010-04-22 Fremgangsmater for behandling av reumatoid artritt ved anvendelse av opploselig mutant CTLA4 molekyl NO20100580L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21591300P 2000-07-03 2000-07-03
PCT/US2001/021204 WO2002002638A2 (en) 2000-07-03 2001-07-02 Methods for treating rheumatic diseases using a soluble ctla4 molecule

Publications (1)

Publication Number Publication Date
NO20100580L true NO20100580L (no) 2003-02-19

Family

ID=22804919

Family Applications (3)

Application Number Title Priority Date Filing Date
NO20026264A NO20026264L (no) 2000-07-03 2002-12-27 Fremgangsmater for behandling av revmatiske sykdommer ved anvendelse av et loselig CTLA4-molekyl
NO20100580A NO20100580L (no) 2000-07-03 2010-04-22 Fremgangsmater for behandling av reumatoid artritt ved anvendelse av opploselig mutant CTLA4 molekyl
NO20100579A NO20100579L (no) 2000-07-03 2010-04-22 Fremgangsmater for behandling av reumatoid artritt ved anvendelse av opploselig mutant CTLA4 molekyl

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO20026264A NO20026264L (no) 2000-07-03 2002-12-27 Fremgangsmater for behandling av revmatiske sykdommer ved anvendelse av et loselig CTLA4-molekyl

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20100579A NO20100579L (no) 2000-07-03 2010-04-22 Fremgangsmater for behandling av reumatoid artritt ved anvendelse av opploselig mutant CTLA4 molekyl

Country Status (38)

Country Link
US (1) US7455835B2 (no)
EP (4) EP3384924A1 (no)
JP (1) JP2004517806A (no)
KR (3) KR20030017606A (no)
CN (1) CN1318086C (no)
AR (2) AR035037A1 (no)
AT (1) ATE401909T1 (no)
AU (2) AU7317401A (no)
BG (2) BG66024B1 (no)
BR (1) BR0112104A (no)
CA (2) CA2630062C (no)
CY (3) CY1109786T1 (no)
CZ (1) CZ303959B6 (no)
DE (1) DE60135029D1 (no)
DK (2) DK1372696T3 (no)
EE (1) EE05378B1 (no)
ES (2) ES2667203T3 (no)
HR (1) HRP20030071B1 (no)
HU (3) HU227669B1 (no)
IL (2) IL153593A0 (no)
IS (1) IS2834B (no)
LT (2) LT1935427T (no)
LV (1) LV12993B (no)
MX (1) MXPA02012603A (no)
MY (1) MY137552A (no)
NO (3) NO20026264L (no)
PE (1) PE20020772A1 (no)
PL (2) PL207534B1 (no)
PT (2) PT1372696E (no)
RS (1) RS50811B (no)
RU (1) RU2287340C2 (no)
SI (3) SI1935427T1 (no)
SK (1) SK287940B6 (no)
TR (1) TR201807700T4 (no)
TW (2) TWI322153B (no)
UY (1) UY26815A1 (no)
WO (1) WO2002002638A2 (no)
ZA (1) ZA200210058B (no)

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