NO301481B1 - DNA-fragmenter som koder for analoger av human IL-3, ekspresjonsvektor inneholdende DNA'et, vertscelle transformert med ekspresjonsvektoren og fremgangsmåte for fremstilling av et polypeptid analogt med IL-3 - Google Patents

DNA-fragmenter som koder for analoger av human IL-3, ekspresjonsvektor inneholdende DNA'et, vertscelle transformert med ekspresjonsvektoren og fremgangsmåte for fremstilling av et polypeptid analogt med IL-3 Download PDF

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Publication number
NO301481B1
NO301481B1 NO903544A NO903544A NO301481B1 NO 301481 B1 NO301481 B1 NO 301481B1 NO 903544 A NO903544 A NO 903544A NO 903544 A NO903544 A NO 903544A NO 301481 B1 NO301481 B1 NO 301481B1
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NO
Norway
Prior art keywords
fom
human
amino acids
empty
protein
Prior art date
Application number
NO903544A
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English (en)
Norwegian (no)
Other versions
NO903544D0 (no
NO903544L (no
Inventor
Lambertus Christiaan Dorssers
Robert Willem Van Leen
Original Assignee
Gist Brocades Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26121243&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO301481(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gist Brocades Bv filed Critical Gist Brocades Bv
Publication of NO903544D0 publication Critical patent/NO903544D0/no
Publication of NO903544L publication Critical patent/NO903544L/no
Publication of NO301481B1 publication Critical patent/NO301481B1/no

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5403—IL-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
NO903544A 1989-08-14 1990-08-13 DNA-fragmenter som koder for analoger av human IL-3, ekspresjonsvektor inneholdende DNA'et, vertscelle transformert med ekspresjonsvektoren og fremgangsmåte for fremstilling av et polypeptid analogt med IL-3 NO301481B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP89202082 1989-08-14
EP89202331 1989-09-14

Publications (3)

Publication Number Publication Date
NO903544D0 NO903544D0 (no) 1990-08-13
NO903544L NO903544L (no) 1991-02-15
NO301481B1 true NO301481B1 (no) 1997-11-03

Family

ID=26121243

Family Applications (1)

Application Number Title Priority Date Filing Date
NO903544A NO301481B1 (no) 1989-08-14 1990-08-13 DNA-fragmenter som koder for analoger av human IL-3, ekspresjonsvektor inneholdende DNA'et, vertscelle transformert med ekspresjonsvektoren og fremgangsmåte for fremstilling av et polypeptid analogt med IL-3

Country Status (17)

Country Link
EP (2) EP0413383B1 (de)
JP (1) JP3192416B2 (de)
AT (1) ATE154638T1 (de)
AU (1) AU636641B2 (de)
CA (1) CA2023246C (de)
DD (1) DD301724A9 (de)
DE (1) DE69030937T2 (de)
DK (1) DK0413383T3 (de)
ES (1) ES2106017T3 (de)
FI (1) FI105192B (de)
GR (1) GR3024679T3 (de)
HU (1) HUT54411A (de)
IE (2) IE902921A1 (de)
IL (1) IL95350A0 (de)
NO (1) NO301481B1 (de)
NZ (1) NZ234869A (de)
PT (1) PT94992B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE179211T1 (de) * 1991-10-07 1999-05-15 Medvet Science Pty Ltd Menschliche il-3-varianten
US6057133A (en) * 1992-11-24 2000-05-02 G. D. Searle Multivariant human IL-3 fusion proteins and their recombinant production
JPH08503706A (ja) * 1992-11-24 1996-04-23 ジー．ディー．サール アンド カンパニー インターロイキン−３（ｉｌ−３）多重変異ポリペプチド
US6153183A (en) * 1992-11-24 2000-11-28 G. D. Searle & Company Co-administration of interleukin-3 mutant polypeptides with CSF's or cytokines for multi-lineage hematopoietic cell production
US6403076B1 (en) 1992-11-24 2002-06-11 S. Christopher Bauer Compositions for increasing hematopoiesis with interleukin-3 mutants
US5772992A (en) * 1992-11-24 1998-06-30 G.D. Searle & Co. Compositions for co-administration of interleukin-3 mutants and other cytokines and hematopoietic factors
US5738849A (en) * 1992-11-24 1998-04-14 G. D. Searle & Co. Interleukin-3 (IL-3) variant fusion proteins, their recombinant production, and therapeutic compositions comprising them
US6361977B1 (en) * 1992-11-24 2002-03-26 S. Christopher Bauer Methods of using multivariant IL-3 hematopoiesis fusion protein
US6413509B1 (en) 1992-11-24 2002-07-02 S. Christopher Bauer Methods of ex-vivo expansion of hematopoietic cells using interleukin-3 mutant polypeptides with other hematopoietic growth factors
US6361976B1 (en) 1992-11-24 2002-03-26 S. Christopher Bauer Co-administration of interleukin-3 mutant polypeptides with CSF'S for multi-lineage hematopoietic cell production
US5501962A (en) * 1993-06-21 1996-03-26 G. D. Searle & Co. Interleuken-3 (IL-3) human/murine hybrid polypeptides and recombinant production of the same
NZ269766A (en) * 1993-07-28 1998-01-26 Medvet Science Pty Ltd Haemopoietic growth factor antagonists; relates to modified forms of such factors
US6465616B1 (en) 1994-04-08 2002-10-15 Bresagen Limited Interleukin-5 antagonist
US6017523A (en) * 1995-06-06 2000-01-25 G.D. Searle & Co. Therapeutic methods employing mutant human interleukin-3 (IL-3) polypeptides
US6270758B1 (en) 1998-10-08 2001-08-07 Duke University Substantially non-toxic biologically active mucosal adjuvants in vertebrate subjects
JP4735670B2 (ja) * 2008-06-11 2011-07-27 富士ゼロックス株式会社 プリント基板および画像処理装置

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR871029B (en) 1986-07-14 1987-11-02 Genetics Inst Novel osteoinductive factors
AU617095B2 (en) 1986-12-16 1991-11-21 Dsm N.V. Molecular cloning and expression of human il-3
EP0790307A1 (de) 1986-12-16 1997-08-20 Gist-Brocades B.V. Molekulare Klonierung und Expression von menschlichem IL-3
EP0342206A4 (en) * 1987-01-20 1990-09-19 Immunex Corporation Human interleukin-3 proteins
US4743264A (en) * 1987-02-05 1988-05-10 Sherva Parker Carole J External prothesis with magnetic field
OA09736A (en) * 1987-02-18 1993-11-30 Schering Biotech Corp "Human interleukin-3 and muteins thereof".

Also Published As

Publication number Publication date
FI105192B (fi) 2000-06-30
DE69030937D1 (de) 1997-07-24
PT94992B (pt) 1997-09-30
FI903996A0 (fi) 1990-08-13
JPH0420295A (ja) 1992-01-23
AU636641B2 (en) 1993-05-06
EP0810285A2 (de) 1997-12-03
NZ234869A (en) 1991-12-23
EP0810285A3 (de) 1998-07-08
CA2023246C (en) 2002-02-19
PT94992A (pt) 1991-04-18
NO903544D0 (no) 1990-08-13
DK0413383T3 (da) 1997-07-07
AU6096090A (en) 1991-02-14
JP3192416B2 (ja) 2001-07-30
EP0413383B1 (de) 1997-06-18
HUT54411A (en) 1991-02-28
GR3024679T3 (en) 1997-12-31
IE980055A1 (en) 2000-02-23
NO903544L (no) 1991-02-15
DE69030937T2 (de) 1997-10-09
ATE154638T1 (de) 1997-07-15
CA2023246A1 (en) 1991-02-15
EP0413383A1 (de) 1991-02-20
ES2106017T3 (es) 1997-11-01
DD301724A9 (de) 1993-08-12
IE902921A1 (en) 1991-02-27
IL95350A0 (en) 1991-06-30

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