NO301844B1 - DNA-molekyl som koder for en polypeptidanalog til S1-underenheten i Bordetella-eksotoksin, og fremgangsmåte for fremstilling av en proteinanalog til S1-underenheten i Bordetella-eksotoksin - Google Patents

DNA-molekyl som koder for en polypeptidanalog til S1-underenheten i Bordetella-eksotoksin, og fremgangsmåte for fremstilling av en proteinanalog til S1-underenheten i Bordetella-eksotoksin Download PDF

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Publication number
NO301844B1
NO301844B1 NO891842A NO891842A NO301844B1 NO 301844 B1 NO301844 B1 NO 301844B1 NO 891842 A NO891842 A NO 891842A NO 891842 A NO891842 A NO 891842A NO 301844 B1 NO301844 B1 NO 301844B1
Authority
NO
Norway
Prior art keywords
subunit
recombinant
protein
toxin
subunits
Prior art date
Application number
NO891842A
Other languages
English (en)
Norwegian (no)
Other versions
NO891842D0 (no
NO891842L (no
Inventor
Iii Walter Neal Burnette
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26788722&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO301844(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of NO891842D0 publication Critical patent/NO891842D0/no
Publication of NO891842L publication Critical patent/NO891842L/no
Publication of NO301844B1 publication Critical patent/NO301844B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K2039/10—Brucella; Bordetella, e.g. Bordetella pertussis; Not used, see subgroups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
NO891842A 1987-09-04 1989-05-03 DNA-molekyl som koder for en polypeptidanalog til S1-underenheten i Bordetella-eksotoksin, og fremgangsmåte for fremstilling av en proteinanalog til S1-underenheten i Bordetella-eksotoksin NO301844B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9430787A 1987-09-04 1987-09-04
US23248288A 1988-08-17 1988-08-17
PCT/US1988/002983 WO1989001976A1 (fr) 1987-09-04 1988-08-26 Analogues de sous-unites de toxine de bordetella derives d'adn recombinant

Publications (3)

Publication Number Publication Date
NO891842D0 NO891842D0 (no) 1989-05-03
NO891842L NO891842L (no) 1989-06-21
NO301844B1 true NO301844B1 (no) 1997-12-15

Family

ID=26788722

Family Applications (2)

Application Number Title Priority Date Filing Date
NO891842A NO301844B1 (no) 1987-09-04 1989-05-03 DNA-molekyl som koder for en polypeptidanalog til S1-underenheten i Bordetella-eksotoksin, og fremgangsmåte for fremstilling av en proteinanalog til S1-underenheten i Bordetella-eksotoksin
NO19972642A NO325016B1 (no) 1987-09-04 1997-06-09 Fremgangsmate for fremstilling av en proteinanalog til Bordetella-eksotoksin, polypeptidanalog av S1-subenhet fra Bordetella pertussis-toksin og vaksine mot pertussis.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO19972642A NO325016B1 (no) 1987-09-04 1997-06-09 Fremgangsmate for fremstilling av en proteinanalog til Bordetella-eksotoksin, polypeptidanalog av S1-subenhet fra Bordetella pertussis-toksin og vaksine mot pertussis.

Country Status (16)

Country Link
US (1) US5773600A (fr)
EP (2) EP0629696A1 (fr)
JP (1) JP2918895B2 (fr)
KR (1) KR0168039B1 (fr)
CN (1) CN1033866C (fr)
AT (1) ATE125568T1 (fr)
CA (1) CA1341560C (fr)
DE (1) DE3854213T3 (fr)
DK (1) DK175821B1 (fr)
ES (1) ES2076160T5 (fr)
FI (1) FI101632B (fr)
GR (1) GR3017497T3 (fr)
IE (1) IE69753B1 (fr)
IL (3) IL87608A0 (fr)
NO (2) NO301844B1 (fr)
WO (1) WO1989001976A1 (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1223334B (it) * 1987-11-02 1990-09-19 Sclavo Spa Polipeptidi immunologicamente attivi con una tossicita' alterata utili per la preparazione di un vaccino antipertosse
US6713072B1 (en) * 1987-11-02 2004-03-30 Chiron S.R.L. Immunologically active polypeptides with altered toxicity useful for the preparation of an antipertussis vaccine
US5925546A (en) * 1987-11-02 1999-07-20 Chiron S.P.A. Immunologically active polypeptides with altered toxicity useful for the preparation of an antipertussis vaccine
GB8727489D0 (en) * 1987-11-24 1987-12-23 Connaught Lab Detoxification of pertussis toxin
US5332583A (en) * 1987-11-24 1994-07-26 Connaught Laboratories Limited Vaccine containing genetically-detoxified pertussis holotoxin
US5358868A (en) * 1987-11-24 1994-10-25 Connaught Laboratories Limited Genetic detoxification of pertussis toxin
CA2009991A1 (fr) * 1989-02-15 1990-08-15 Witold Cieplak Gene de la toxine coquelucheuse, clonage et expression de l'antigene protecteur
US7232671B2 (en) * 1989-02-15 2007-06-19 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Pertussis toxin gene: cloning and expression of protective antigen
ATE127347T1 (de) * 1989-04-28 1995-09-15 Sclavo Spa Pertussistoxin-mutanten, dieselbe produzierende bordetella-stämme und ihre verwendung als vakzin gegen pertussis.
US5786189A (en) * 1989-11-29 1998-07-28 Smithkline Beecham Biologicals (S.A.) Vaccine
GB9326174D0 (en) * 1993-12-22 1994-02-23 Biocine Sclavo Mucosal adjuvant
US20030072774A1 (en) * 1994-06-10 2003-04-17 Diane M. Gajewczyk Proteinaceous adjuvants
PT1393744E (pt) * 1995-05-04 2011-05-03 Sanofi Pasteur Ltd Vacinas acelulares contra a tosse convulsa e m?todos para a sua prepara??o
EP0912726A4 (fr) * 1996-05-10 2001-07-18 Phylomed Corp Procedes permettant d'oxyder des liaisons bisulfure avec de l'ozone
FR2754543B1 (fr) * 1996-10-11 1998-12-31 Pasteur Institut Souche de bordetella deficiente dans la production de toxine et exprimant une proteine hydride, liposomes comprenant de la fha et leurs utilisations comme vaccins, et utilisation de la fha pour stimuler les reponses immunitaires
US6818222B1 (en) 1997-03-21 2004-11-16 Chiron Corporation Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants
US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
GB0313916D0 (en) 2003-06-16 2003-07-23 Glaxosmithkline Biolog Sa Vaccine composition
EP1774017B1 (fr) 2004-07-26 2013-05-15 Pfenex Inc. Procede permettant d'ameliorer l'expression d'une proteine par mise au point d'une souche par genie genetique
PT1828378E (pt) * 2004-12-17 2014-10-10 Staat Der Nederlanden Vert Door De Minister Van Vws Ministerie Van Volksgezondheid Welzijn En Sport Deacilação de lps em bactérias de gram negativo
US9394571B2 (en) 2007-04-27 2016-07-19 Pfenex Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
ITMI20090946A1 (it) 2009-05-28 2010-11-29 Novartis Ag Espressione di proteine ricombinanti
EP2553102B1 (fr) 2010-03-30 2015-12-09 Pfenex Inc. Expression de protéines de toxines recombinantes en forte quantité
US9169304B2 (en) 2012-05-01 2015-10-27 Pfenex Inc. Process for purifying recombinant Plasmodium falciparum circumsporozoite protein
SG11201500573RA (en) 2012-08-06 2015-02-27 Glaxosmithkline Biolog Sa Method for eliciting in infants an immune response against rsv and b. pertussis
US20140037680A1 (en) 2012-08-06 2014-02-06 Glaxosmithkline Biologicals, S.A. Novel method
CN105007936B (zh) 2013-03-08 2018-10-02 扬森疫苗与预防公司 无细胞百日咳疫苗
AU2014304545A1 (en) 2013-08-05 2016-02-25 Glaxosmithkline Biologicals S.A. Combination immunogenic compositions
CN109172818B (zh) * 2018-08-02 2021-10-22 浙江康佰裕生物科技有限公司 一种蛋白牛痘疫苗及其效力检测方法
WO2020081548A1 (fr) * 2018-10-15 2020-04-23 Arizona Board Of Regents On Behalf Of The University Of Arizona Procédés et compositions de polypeptide de vaccin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4704362A (en) * 1977-11-08 1987-11-03 Genentech, Inc. Recombinant cloning vehicle microbial polypeptide expression
FR2590483B1 (fr) * 1985-11-22 1988-12-09 Pasteur Institut Antigenes purifies ayant des proprietes vaccinantes contre b. pertussis, moyens notamment adns recombinants pour les produire et compositions de vaccins les contenant
CA1340373C (fr) * 1986-01-28 1999-02-02 Rino Rappuoli Clonage et sequencage du fragment d'adn qui code les cinq sous-unites de l'anatoxine coquelucheuse, plasmide hybride contenant le fragment d'adnet microorganismes transformes par le plasmide hybride et capables d'exprimer toutes les sous-unites de l'anatoxine coquelucheuse ou certaines d'entre elles
DE3781541T2 (de) * 1986-12-23 1993-05-06 Univ Leland Stanford Junior Modifiziertes pertussistoxin.
IT1223334B (it) * 1987-11-02 1990-09-19 Sclavo Spa Polipeptidi immunologicamente attivi con una tossicita' alterata utili per la preparazione di un vaccino antipertosse
GB8727489D0 (en) * 1987-11-24 1987-12-23 Connaught Lab Detoxification of pertussis toxin
IT1223529B (it) * 1987-12-18 1990-09-19 Sclavo Spa Epitopo immunodominante protettivo contenuto nella subunita' s1 della tossina della pertosse

Also Published As

Publication number Publication date
ES2076160T5 (es) 2004-12-01
CN1033072A (zh) 1989-05-24
EP0306318B2 (fr) 2004-04-28
IL87608A0 (en) 1989-01-31
FI892131A0 (fi) 1989-05-03
AU623867B2 (en) 1992-05-28
DK216289A (da) 1989-06-30
DE3854213D1 (de) 1995-08-31
DE3854213T3 (de) 2004-10-21
DE3854213T2 (de) 1995-12-07
WO1989001976A1 (fr) 1989-03-09
AU2386488A (en) 1989-03-31
JPH04501051A (ja) 1992-02-27
FI101632B1 (fi) 1998-07-31
EP0629696A1 (fr) 1994-12-21
JP2918895B2 (ja) 1999-07-12
NO325016B1 (no) 2008-01-14
KR890701758A (ko) 1989-12-21
US5773600A (en) 1998-06-30
IE882668L (en) 1989-03-04
FI892131L (fi) 1989-05-03
GR3017497T3 (en) 1995-12-31
IE69753B1 (en) 1996-10-02
ATE125568T1 (de) 1995-08-15
NO891842D0 (no) 1989-05-03
NO891842L (no) 1989-06-21
DK175821B1 (da) 2005-03-14
DK216289D0 (da) 1989-05-03
CN1033866C (zh) 1997-01-22
EP0306318B1 (fr) 1995-07-26
EP0306318A1 (fr) 1989-03-08
NO972642D0 (no) 1997-06-09
IL103121A0 (en) 1993-02-21
CA1341560C (fr) 2007-10-30
ES2076160T3 (es) 1995-11-01
KR0168039B1 (ko) 1999-01-15
NO972642L (no) 1997-07-28
FI101632B (fi) 1998-07-31
IL103121A (en) 1995-08-31

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