NO301985B1 - Fremgangsmåte for fremstilling av 3-des-hydroksy-cystatin C eller en homolog derav, plasmid samt mikroorganisme for anvendelse ved utförelse av fremgangsmåten - Google Patents

Fremgangsmåte for fremstilling av 3-des-hydroksy-cystatin C eller en homolog derav, plasmid samt mikroorganisme for anvendelse ved utförelse av fremgangsmåten Download PDF

Info

Publication number
NO301985B1
NO301985B1 NO890260A NO890260A NO301985B1 NO 301985 B1 NO301985 B1 NO 301985B1 NO 890260 A NO890260 A NO 890260A NO 890260 A NO890260 A NO 890260A NO 301985 B1 NO301985 B1 NO 301985B1
Authority
NO
Norway
Prior art keywords
cystatin
des
plasmid
sequence
hydroxy
Prior art date
Application number
NO890260A
Other languages
English (en)
Norwegian (no)
Other versions
NO890260D0 (no
NO890260L (no
Inventor
Anders Grubb
Aake Lundwall
Magnus Abrahamson
Henrik Dalboege
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO890260D0 publication Critical patent/NO890260D0/no
Publication of NO890260L publication Critical patent/NO890260L/no
Publication of NO301985B1 publication Critical patent/NO301985B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8139Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Cardiology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Electronic Switches (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO890260A 1987-05-22 1989-01-20 Fremgangsmåte for fremstilling av 3-des-hydroksy-cystatin C eller en homolog derav, plasmid samt mikroorganisme for anvendelse ved utförelse av fremgangsmåten NO301985B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK260987A DK260987D0 (da) 1987-05-22 1987-05-22 Fremgangsmaade til fremstilling af et humant protein samt dna-sekvens til anvendelse ved udoevelse af fremgangsmaaden
PCT/DK1988/000082 WO1988009384A1 (en) 1987-05-22 1988-05-20 Method of producing cystatin c or modifications hereof and dna-sequence for use when carrying out the method

Publications (3)

Publication Number Publication Date
NO890260D0 NO890260D0 (no) 1989-01-20
NO890260L NO890260L (no) 1989-01-20
NO301985B1 true NO301985B1 (no) 1998-01-05

Family

ID=8113675

Family Applications (1)

Application Number Title Priority Date Filing Date
NO890260A NO301985B1 (no) 1987-05-22 1989-01-20 Fremgangsmåte for fremstilling av 3-des-hydroksy-cystatin C eller en homolog derav, plasmid samt mikroorganisme for anvendelse ved utförelse av fremgangsmåten

Country Status (12)

Country Link
EP (1) EP0362259B1 (de)
JP (1) JP3011274B2 (de)
AT (1) ATE135049T1 (de)
AU (1) AU619750B2 (de)
CA (1) CA1340862C (de)
DE (1) DE3855078T2 (de)
DK (1) DK260987D0 (de)
ES (1) ES2013337A6 (de)
FI (1) FI102191B1 (de)
IL (1) IL86476A (de)
NO (1) NO301985B1 (de)
WO (1) WO1988009384A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2002820A1 (en) * 1988-11-18 1990-05-18 Kazunori Hanada Pharmaceutical use for cystatins
GB9122051D0 (en) * 1991-10-17 1991-11-27 Univ Nottingham Medicines
GB9403819D0 (en) * 1994-02-28 1994-04-20 Univ Leeds Control of parasites
AU738766B2 (en) * 1994-11-21 2001-09-27 University Of Leeds, The Modified proteinase inhibitors
AU715747B2 (en) * 1994-11-21 2000-02-10 University Of Leeds, The Modified proteinase inhibitors
EP0842187A4 (de) * 1995-06-05 2000-04-12 Human Genome Sciences Inc Humancystanin e
US6011012A (en) 1995-06-05 2000-01-04 Human Genome Sciences, Inc. Human cystatin E
WO2000008159A2 (en) * 1998-08-05 2000-02-17 The University Of British Columbia Production and use of modified cystatins
WO2000033791A2 (en) * 1998-12-11 2000-06-15 The Salk Institute For Biological Studies Co-factors for trophic factors, and methods of use thereof
EP1176200A3 (de) 2000-06-20 2005-01-12 Switch Biotech Aktiengesellschaft Verwendung von Polypeptiden oder diese kodierende Nukleinsäuren zur Diagnose oder Behandlung von Hauterkrankung oder Wundheilung sowie ihre Verwendung zur Indentifizierung von pharmakologisch aktiven Substanzen
JP6203723B2 (ja) * 2012-07-31 2017-09-27 雪印メグミルク株式会社 骨疾患の予防又は治療用タンパク質素材及びその製造方法
CN102895658A (zh) * 2012-08-23 2013-01-30 苏州大学附属第一医院 Cystatin C在治疗蛛网膜下腔出血后发生的脑血管痉挛的应用
CN106119286A (zh) * 2016-08-10 2016-11-16 吴江近岸蛋白质科技有限公司 表达载体及其高效表达和制备人胱抑素c蛋白的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775624A (en) * 1985-02-08 1988-10-04 Eli Lilly And Company Vectors and compounds for expression of human protein C

Also Published As

Publication number Publication date
FI895553A0 (fi) 1989-11-21
DE3855078D1 (de) 1996-04-11
AU1939988A (en) 1988-12-21
WO1988009384A1 (en) 1988-12-01
IL86476A0 (en) 1988-11-15
JPH03501201A (ja) 1991-03-22
EP0362259B1 (de) 1996-03-06
CA1340862C (en) 1999-12-28
IL86476A (en) 1994-01-25
FI102191B (fi) 1998-10-30
NO890260D0 (no) 1989-01-20
EP0362259A1 (de) 1990-04-11
AU619750B2 (en) 1992-02-06
ES2013337A6 (es) 1990-05-01
DK260987D0 (da) 1987-05-22
NO890260L (no) 1989-01-20
JP3011274B2 (ja) 2000-02-21
ATE135049T1 (de) 1996-03-15
FI102191B1 (fi) 1998-10-30
DE3855078T2 (de) 1996-07-18

Similar Documents

Publication Publication Date Title
US6774107B1 (en) Protein for blocking platelet adhesion
JPH0687778B2 (ja) ヒト抗トロンビン▲iii▼
NO301985B1 (no) Fremgangsmåte for fremstilling av 3-des-hydroksy-cystatin C eller en homolog derav, plasmid samt mikroorganisme for anvendelse ved utförelse av fremgangsmåten
Nilsson et al. A signal peptide with a proline next to the cleavage site inhibits leader peptidase when present in a sec‐independent protein
NO301480B1 (no) Fremgangsmåte for enzymatisk fremstilling av basisk fibroblastfaktor
US5332804A (en) High molecular weight human angiogenic basic fibroblast growth factors
EP0687731B1 (de) Sekretionsvektor, diesen enthaltene transformierte Mikroorganismen und Herstellung von Produkten durch obigen Mikroorganismus
JPH01104178A (ja) エンケファリナーゼの製造方法、アッセイ法およびそれを含有する医薬組成物
WO1992007935A1 (en) Glycosaminoglycan-targeted fusion proteins, their design, construction and compositions
JP2000074922A (ja) シュードモナス・アエルギノザの外部膜タンパク質f
JPH05506646A (ja) ヒト・フォンビルブラント因子のクローニング及び製造、並びにその使用方法
US5432264A (en) Recombinant 3-des-OH-cystatin C produced by expression in a procaryotic host cell
McILHINNEY et al. Characterization of a polyhistidine‐tagged form of human myristoyl‐CoA: protein N‐myristoyltransferase produced in Escherichia coli
EP0251730A2 (de) Herstellung von menschlichem Lysozym
CN101506226A (zh) 改良的色素上皮衍生因子变体及其用途
DK172400B1 (da) Fremgangsmåde til fremstilling af renset minactivin, minactivinkodende DNA-molekyle, rekombinant DNA-molekyle, sammensmeltet gen, vært, reagent til lokalisering og definering af grænserne for tumorer i histologiske prøver, samt anvendelse af det rekombinante DNA-molekyle, minactivinet og peptider deraf
US5188943A (en) Method of producing high molecular weight human fibroblast growth factors
WO1994029448A1 (en) Dna and protein coded for thereby
Isono et al. Mutation leading to gene fusion in the histidine operon of Salmonella typhimurium
TW200906433A (en) Therapeutic agent for acute hepatitis or prophylactic and/or therapeutic agent for fulminant hepatitis
US7993893B2 (en) Haemocoagulase
JPH10507919A (ja) ヒト及び植物メチルトランスフェラーゼの製造及び用途
EP0322084A2 (de) Tumorzellenhemmender Faktor
CN101173003A (zh) 尖吻蝮蛇毒凝血酶原激活剂、其编码序列及用途
RU2130071C1 (ru) Вектор секреции для получения гирудина hv1 (варианты), рекомбинантный штамм escherichia coli - продуцент гирудина hv1 и способ его получения

Legal Events

Date Code Title Description
MK1K Patent expired