NO303390B1 - FremgangsmÕte for fast-fasesyntese av et peptid inneholdende minst en aza-aminosyre - Google Patents

FremgangsmÕte for fast-fasesyntese av et peptid inneholdende minst en aza-aminosyre Download PDF

Info

Publication number: NO303390B1
Authority: NO; Norway
Prior art keywords: solid; peptide; aza; amino acid; synthesis
Prior art date: 1991-06-14

Application number

NO922319A

Other languages

English (en)

Norwegian (no)

Other versions

NO922319L (no

NO922319D0 (no

Inventor

Ronald Cotton

Michael Brian Giles

Original Assignee

Zeneca Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-06-14

Filing date

1992-06-12

Publication date

1998-07-06

1992-06-12 Application filed by Zeneca Ltd filed Critical Zeneca Ltd

1992-06-12 Publication of NO922319D0 publication Critical patent/NO922319D0/no

1992-12-15 Publication of NO922319L publication Critical patent/NO922319L/no

1998-07-06 Publication of NO303390B1 publication Critical patent/NO303390B1/no

Links

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XINVEYSHJUWQDS-UHFFFAOYSA-N tert-butyl n-amino-n-benzylcarbamate Chemical compound CC(C)(C)OC(=O)N(N)CC1=CC=CC=C1 XINVEYSHJUWQDS-UHFFFAOYSA-N 0.000 description 1
KJAMZCVTJDTESW-UHFFFAOYSA-N tiracizine Chemical compound C1CC2=CC=CC=C2N(C(=O)CN(C)C)C2=CC(NC(=O)OCC)=CC=C21 KJAMZCVTJDTESW-UHFFFAOYSA-N 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Life Sciences & Earth Sciences (AREA)
Analytical Chemistry (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

NO922319A 1991-06-14 1992-06-12 FremgangsmÕte for fast-fasesyntese av et peptid inneholdende minst en aza-aminosyre NO303390B1 (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB919112825A GB9112825D0 (en)	1991-06-14	1991-06-14	Process for making peptides

Publications (3)

Publication Number	Publication Date
NO922319D0 NO922319D0 (no)	1992-06-12
NO922319L NO922319L (no)	1992-12-15
NO303390B1 true NO303390B1 (no)	1998-07-06

Family

ID=10696665

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO922319A NO303390B1 (no)	1991-06-14	1992-06-12	FremgangsmÕte for fast-fasesyntese av et peptid inneholdende minst en aza-aminosyre

Country Status (10)

Country	Link
US (1)	US5602231A (fr)
EP (1)	EP0518655B1 (fr)
JP (1)	JP3249178B2 (fr)
AT (1)	ATE157986T1 (fr)
AU (1)	AU667035B2 (fr)
CA (1)	CA2069724C (fr)
DE (1)	DE69222091T2 (fr)
ES (1)	ES2106831T3 (fr)
GB (1)	GB9112825D0 (fr)
NO (1)	NO303390B1 (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9319776D0 (en) *	1993-09-24	1993-11-10	Medical Res Council	Azapeptide synthesis
DE69519182T2 (de) *	1994-03-17	2001-05-17	Fujirebio Inc., Tokio/Tokyo	Azapeptid-Derivate
ES2154590B1 (es)	1999-05-20	2001-11-01	Lipotec Sa	Procedimiento de sintesis de peptidos en fase solida
JP2006501150A (ja) *	2002-05-03	2006-01-12	アベシア・リミテッド	ペプチド合成のためのプロセス
PT1737889E (pt)	2004-10-19	2010-12-13	Lonza Ag	Método para síntese de péptidos em fase sólida
ES2336826T3 (es)	2005-05-03	2010-04-16	Novetide, Ltd.	Procedimientos para la produccion de un peptido que presenta una amida c-terminal.
WO2008044890A1 (fr) *	2006-10-12	2008-04-17	Dong Kook Pharm. Co., Ltd	Procédé permettant de préparer des peptides par synthèse en phase solide
KR101046846B1 (ko)	2006-10-12	2011-07-06	동국제약 주식회사	고체상 합성법을 이용한 펩타이드의 제조방법
WO2010141276A1 (fr) *	2009-06-03	2010-12-09	Mallinckrodt Inc.	Procédé de synthèse peptidique en phase solide pour la production de goséréline
CN102690329B (zh) *	2011-03-25	2014-06-04	杭州九源基因工程有限公司	一种戈舍瑞林多肽的纯化生产方法
CN102190709A (zh) *	2011-03-31	2011-09-21	厦门博欣生物技术有限公司	促黄体生成素释放激素衍生物的合成方法
CN102746383A (zh) *	2011-04-21	2012-10-24	杭州九源基因工程有限公司	一种戈舍瑞林的合成方法
US10450343B2 (en)	2013-03-21	2019-10-22	Sanofi-Aventis Deutschland Gmbh	Synthesis of cyclic imide containing peptide products
CA2907454C (fr)	2013-03-21	2021-05-04	Sanofi-Aventis Deutschland Gmbh	Synthese de produits peptidiques contenant de l'hydantoine
KR20170014624A (ko) *	2015-07-30	2017-02-08	주식회사 대웅제약	Tdm-621의 제조방법
CN105884865A (zh) *	2016-05-18	2016-08-24	江苏开元药业有限公司	一种戈舍瑞林的合成方法
CN106589072B (zh) *	2016-12-22	2020-08-18	江苏诺泰澳赛诺生物制药股份有限公司	一种戈舍瑞林的合成法
JP2020505379A (ja)	2017-01-20	2020-02-20	イミューンシステムレギュレェイションホールディングエービー	新規化合物（イムノレリン）
JP2020505378A (ja)	2017-01-20	2020-02-20	イミューンシステムレギュレェイションホールディングエービー	新規化合物（イムノヘリン−細胞内感染）
US11883461B2 (en)	2019-05-09	2024-01-30	The Feinstein Institutes For Medical Research	HMGB1 antagonist treatment of severe sepsis
WO2020227592A1 (fr)	2019-05-09	2020-11-12	The Feinstein Institutes For Medical Research	Thiosemicarbazates et leurs utilisations
EP3965792A4 (fr)	2019-05-09	2023-01-18	The Feinstein Institutes for Medical Research	Antagoniste de hmgb1
IL287499B2 (en)	2019-05-09	2025-11-01	Feinstein Institutes For Medical Research	Compounds for use in synthesis of peptidomimetics
KR20210104460A (ko) *	2020-02-17	2021-08-25	주식회사 아이바이오코리아	고체상 합성법을 이용한 펩타이드의 제조 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5116666A (fr) *	1974-07-30	1976-02-10	Shionogi Seiyaku Kk
HU187503B (en) *	1983-03-29	1986-01-28	Magyar Tudomanyos Akademia,Hu	Process for preparing gonadoliberine derivatives containing beta-aspartyl group
DE3523365A1 (de) *	1985-06-29	1987-01-08	Behringwerke Ag	Verbrueckungsreagenz, verfahren zu seiner herstellung und seine anwendung
TW295589B (fr) *	1990-08-30	1997-01-11	Hoechst Ag

1991
- 1991-06-14 GB GB919112825A patent/GB9112825D0/en active Pending
1992
- 1992-05-21 AU AU17040/92A patent/AU667035B2/en not_active Ceased
- 1992-05-27 CA CA002069724A patent/CA2069724C/fr not_active Expired - Fee Related
- 1992-06-11 AT AT92305340T patent/ATE157986T1/de not_active IP Right Cessation
- 1992-06-11 JP JP15178692A patent/JP3249178B2/ja not_active Expired - Fee Related
- 1992-06-11 ES ES92305340T patent/ES2106831T3/es not_active Expired - Lifetime
- 1992-06-11 EP EP92305340A patent/EP0518655B1/fr not_active Expired - Lifetime
- 1992-06-11 DE DE69222091T patent/DE69222091T2/de not_active Expired - Fee Related
- 1992-06-12 NO NO922319A patent/NO303390B1/no unknown
1995
- 1995-05-26 US US08/452,096 patent/US5602231A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0518655A3 (en)	1993-05-05
NO922319L (no)	1992-12-15
ES2106831T3 (es)	1997-11-16
EP0518655B1 (fr)	1997-09-10
NO922319D0 (no)	1992-06-12
CA2069724C (fr)	2003-07-29
CA2069724A1 (fr)	1992-12-15
EP0518655A2 (fr)	1992-12-16
GB9112825D0 (en)	1991-07-31
ATE157986T1 (de)	1997-09-15
DE69222091D1 (de)	1997-10-16
JP3249178B2 (ja)	2002-01-21
DE69222091T2 (de)	1998-01-29
AU1704092A (en)	1992-12-17
AU667035B2 (en)	1996-03-07
JPH05170791A (ja)	1993-07-09
US5602231A (en)	1997-02-11

Publication	Publication Date	Title
NO303390B1 (no)	1998-07-06	FremgangsmÕte for fast-fasesyntese av et peptid inneholdende minst en aza-aminosyre
US4569967A (en)	1986-02-11	Synthesis of N-substituted peptide amides
DK175042B1 (da)	2004-05-10	Kunstharpiks, fremgangsmåde til fremstilling deraf samt fremgangsmåde til fremstilling af peptider og peptidamider under anvendelse af kunstharpiksen
JP4405594B2 (ja)	2010-01-27	改良型固相ペプチド合成及びかかる合成において利用するための試薬
Nakagawa et al.	1983	Synthesis of protected peptide segments and their assembly on a polymer-bound oxime: application to the synthesis of a peptide model for plasma apolipoprotein AI
US3714140A (en)	1973-01-30	Peptide synthesis
CN113444164B (zh)	2022-07-19	一种固相合成索马鲁肽的方法
KR100237126B1 (ko)	2000-01-15	펩티드 유사체의 신속한 합성 및 검색방법
US6897289B1 (en)	2005-05-24	Peptide synthesis procedure in solid phase
US5510460A (en)	1996-04-23	Peptide process
CA1085868A (fr)	1980-09-16	Synthese, en phase solide, de peptides proteges
KR101971418B1 (ko)	2019-04-24	고세렐린의 제조 방법
US6448031B1 (en)	2002-09-10	Process for producing LH-RH derivatives
US4701499A (en)	1987-10-20	Synthesis of N-substituted peptide amides
US4101721A (en)	1978-07-18	Solid phase synthesis of protected peptides
CN111944016B (zh)	2022-04-29	一种醋酸艾替班特的制备方法
KR101971417B1 (ko)	2019-04-24	부세렐린의 제조 방법
CN107344960A (zh)	2017-11-14	地加瑞克的制备方法
CN114945580A (zh)	2022-08-26	用于合成南吉博肽的方法
HARTH‐FRITSCHY et al.	1997	Esterification of 9‐Fluorenylmethoxycarbonyl‐glycosylated serine and cysteine derivatives with an hydroxymethyl resin
CN106317161B (zh)	2020-05-15	一种氟甲基酮肽系列化合物的制备方法
KR0152276B1 (ko)	1998-10-01	Lh-rh 유사체의 일시적 최소 보호합성 방법
Chou et al.	1978	Enzymatic Synthesis of Oligopeptide. Part I. Papain‐Catalyzed Synthesis of Dipeptide, Tripeptide and Tetrapeptide
EP0056274A1 (fr)	1982-07-21	Dérivés de l'indole et procédé de préparation de peptides
JPH10501818A (ja)	1998-02-17	鋳型指向性環化