NO306623B1 - Fremgangsmåte for fremstilling av DNA-molekyl inneholdende deler av et gen som transkriberes av polymerase III og en DNA-sekvens som koder for et inhiberende RNA-molekyl - Google Patents

Fremgangsmåte for fremstilling av DNA-molekyl inneholdende deler av et gen som transkriberes av polymerase III og en DNA-sekvens som koder for et inhiberende RNA-molekyl Download PDF

Info

Publication number: NO306623B1
Authority: NO; Norway
Prior art keywords: dna; trna; rna; ribozyme; producing
Prior art date: 1989-03-16

Application number

NO901213A

Other languages

English (en)

Norwegian (no)

Other versions

NO901213L (no

NO901213D0 (no

Inventor

Hartmut Beug

Max L Birnstiel

Matthew Cotten

Ernst Wagner

Harald Kandolf

Original Assignee

Boehringer Ingelheim Int

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-03-16

Filing date

1990-03-15

Publication date

1999-11-29

1990-03-15 Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int

1990-03-15 Publication of NO901213D0 publication Critical patent/NO901213D0/no

1990-09-17 Publication of NO901213L publication Critical patent/NO901213L/no

1999-11-29 Publication of NO306623B1 publication Critical patent/NO306623B1/no

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Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
- C12N2310/121—Hammerhead

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Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Saccharide Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Enzymes And Modification Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

NO901213A 1989-03-16 1990-03-15 Fremgangsmåte for fremstilling av DNA-molekyl inneholdende deler av et gen som transkriberes av polymerase III og en DNA-sekvens som koder for et inhiberende RNA-molekyl NO306623B1 (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
AT60989		1989-03-16

Publications (3)

Publication Number	Publication Date
NO901213D0 NO901213D0 (no)	1990-03-15
NO901213L NO901213L (no)	1990-09-17
NO306623B1 true NO306623B1 (no)	1999-11-29

Family

ID=3495118

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Application Number	Title	Priority Date	Filing Date
NO901213A NO306623B1 (no)	1989-03-16	1990-03-15	Fremgangsmåte for fremstilling av DNA-molekyl inneholdende deler av et gen som transkriberes av polymerase III og en DNA-sekvens som koder for et inhiberende RNA-molekyl

Country Status (20)

Country	Link
EP (1)	EP0387775B1 (fr)
JP (1)	JP3330930B2 (fr)
KR (1)	KR900014591A (fr)
AT (1)	ATE140961T1 (fr)
AU (1)	AU637354B2 (fr)
CA (1)	CA2012312C (fr)
DD (1)	DD297838A5 (fr)
DE (1)	DE59010432D1 (fr)
DK (1)	DK0387775T3 (fr)
ES (1)	ES2090049T3 (fr)
FI (1)	FI105103B (fr)
GR (1)	GR3020935T3 (fr)
HU (2)	HU215187B (fr)
IE (1)	IE74850B1 (fr)
IL (1)	IL93754A (fr)
NO (1)	NO306623B1 (fr)
NZ (1)	NZ232917A (fr)
PT (1)	PT93440B (fr)
RU (1)	RU2136751C1 (fr)
ZA (1)	ZA901973B (fr)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1990013641A1 (fr) *	1989-05-10	1990-11-15	Sloan-Kettering Institute For Cancer Research	Cellules eucaryotes transformees de maniere stable comprenant un adn etranger susceptible d'etre transcrit sous la direction d'un promoteur pol iii
DE4091533T (fr) *	1989-08-31	1992-01-30
JP2507895B2 (ja) *	1989-12-19	1996-06-19	工業技術院長	リボザイムの新規合成系
US6008343A (en) *	1990-06-19	1999-12-28	Gene Shears Pty. Ltd.	Nucleotide based endonucleases
JPH05509224A (ja) *	1990-06-19	1993-12-22	コモンウェルス　サイエンティフィク　アンド　インダストリアル　リサーチ　オーガナイゼイション	エンドヌクレアーゼ
ES2061416T3 (es) *	1990-10-12	1997-03-01	Max Planck Gesellschaft	Ribozimas modificadas.
DE4104186A1 (de) *	1991-02-12	1992-08-13	Genentech Inc	Neue, ueber endozytose in hoehere eukaryotische zellen aufnehmbare, nukleinsaeure enthaltende komplexe
FR2687411A1 (fr) *	1992-02-13	1993-08-20	Nice Sophia Antipolis Universi	Vecteur comportant un gene viral transcrit par l'arn polymerase iii, et procede de production intracellulaire d'arn.
AU4259193A (en) *	1992-04-28	1993-11-29	Frank Andreas Harald Meyer	Medicament for the gene-therapeutic treatment of human beings, animals and plants, especially to block virus multiplication and carcinogenes and process for producing the medicament
US5989906A (en) *	1992-05-14	1999-11-23	Ribozyme Pharmaceuticals, Inc.	Method and reagent for inhibiting P-glycoprotein (mdr-1-gene)
US5610052A (en) *	1992-08-26	1997-03-11	Ribozyme Pharmaceuticals Inc.	Enzymatic RNA with activity to ras
AU687001B2 (en) *	1992-05-14	1998-02-19	Ribozyme Pharmaceuticals, Inc.	Method and reagent for inhibiting cancer development
CA2114312A1 (fr) *	1992-05-27	1993-12-09	John J. Rossi	Molecules chimeriques arnt-ribozyme
US5827935A (en) *	1992-05-27	1998-10-27	City Of Hope	Chimeric tRNAlys -ribozyme molecules
RU94046396A (ru) *	1992-06-29	1996-11-10	Джин Ширс Пти.Лтд. (AU)	Нуклеиновая кислота, днк, вектор, способ получения растения или животного, способ получения клеток, способ создания животного, животное, трансгенное животное, трансгенное растение, плоды, черенки и семена, растительные клетки, способ вмешательства в репликацию вируса
WO1994013798A1 (fr) *	1992-12-16	1994-06-23	Bergmann Johanna E	Agents destines a la prophylaxie et au traitement de la maladie d'alzheimer chez l'homme
EP0647716B1 (fr) *	1993-07-06	2003-09-24	Universite De Nice-Sophia Antipolis	Vecteur comportant un gène viral transcrit par l'ARN polymérase III
US5837503A (en) *	1993-07-07	1998-11-17	Universite De Nice-Sophia-Antipolis	Vector containing viral gene transcribed by RNA polymerase III and methods for use
US5817635A (en) *	1993-08-09	1998-10-06	Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V.	Modified ribozymes
CA2157015A1 (fr) *	1994-01-24	1995-07-27	John J. Rossi	Co-localisation d'une molecule cible et de ses inhibiteurs
DE4424761C1 (de) *	1994-07-04	1995-06-08	Max Planck Gesellschaft	Expressionskassette für die Antisense- und die Ribozym-Expression
AU708995B2 (en)	1995-06-07	1999-08-19	Gene Shears Pty. Limited	Optimized minizymes and miniribozymes and uses thereof
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1990
- 1990-03-13 DE DE59010432T patent/DE59010432D1/de not_active Expired - Lifetime
- 1990-03-13 DK DK90104701.9T patent/DK0387775T3/da active
- 1990-03-13 EP EP90104701A patent/EP0387775B1/fr not_active Expired - Lifetime
- 1990-03-13 ES ES90104701T patent/ES2090049T3/es not_active Expired - Lifetime
- 1990-03-13 AT AT90104701T patent/ATE140961T1/de not_active IP Right Cessation
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- 1990-03-15 AU AU51301/90A patent/AU637354B2/en not_active Expired
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- 1990-03-15 KR KR1019900003438A patent/KR900014591A/ko not_active Ceased
- 1990-03-15 CA CA002012312A patent/CA2012312C/fr not_active Expired - Lifetime
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- 1990-03-16 RU SU5010032A patent/RU2136751C1/ru active
1995
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Also Published As

Publication number	Publication date
DK0387775T3 (da)	1996-11-04
IL93754A0 (en)	1990-12-23
NO901213L (no)	1990-09-17
PT93440A (pt)	1990-11-07
FI901296A0 (fi)	1990-03-15
EP0387775B1 (fr)	1996-07-31
DD297838A5 (de)	1992-01-23
HU211868A9 (en)	1995-12-28
EP0387775A1 (fr)	1990-09-19
JP3330930B2 (ja)	2002-10-07
NO901213D0 (no)	1990-03-15
CA2012312C (fr)	2001-08-14
CA2012312A1 (fr)	1990-09-16
IE900931L (en)	1990-09-16
NZ232917A (en)	1997-07-27
AU637354B2 (en)	1993-05-27
HU215187B (hu)	1998-10-28
ES2090049T3 (es)	1996-10-16
IL93754A (en)	1995-12-31
AU5130190A (en)	1990-11-01
DE59010432D1 (de)	1996-09-05
IE74850B1 (en)	1997-08-13
HUT54206A (en)	1991-01-28
KR900014591A (ko)	1990-10-24
JPH03130080A (ja)	1991-06-03
RU2136751C1 (ru)	1999-09-10
HU901584D0 (en)	1990-06-28
ZA901973B (en)	1991-11-27
FI105103B (fi)	2000-06-15
GR3020935T3 (en)	1996-12-31
ATE140961T1 (de)	1996-08-15
PT93440B (pt)	2001-07-31

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NO306623B1 (no)	1999-11-29	Fremgangsmåte for fremstilling av DNA-molekyl inneholdende deler av et gen som transkriberes av polymerase III og en DNA-sekvens som koder for et inhiberende RNA-molekyl
CA2125974C (fr)	1999-06-29	Inhibiteurs de la synthese de l'adn derives de cellules senescentes
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US6183959B1 (en)	2001-02-06	Method for target site selection and discovery
JPH10507067A (ja)	1998-07-14	テロメラーゼのｒｎａ成分
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US6830923B1 (en)	2004-12-14	Genetics units for inhibiting the function of RNA
AU2004205192B2 (en)	2007-09-20	Production of ssDNA in vivo