NO306717B1 - Fremgangsmåte for fremstilling av piperidin-karbinoler - Google Patents

Fremgangsmåte for fremstilling av piperidin-karbinoler

Info

Publication number
NO306717B1
NO306717B1 NO953598A NO953598A NO306717B1 NO 306717 B1 NO306717 B1 NO 306717B1 NO 953598 A NO953598 A NO 953598A NO 953598 A NO953598 A NO 953598A NO 306717 B1 NO306717 B1 NO 306717B1
Authority
NO
Norway
Prior art keywords
preparation
piperidine carbinols
carbinols
piperidine
Prior art date
Application number
NO953598A
Other languages
English (en)
Norwegian (no)
Other versions
NO953598D0 (no
NO953598L (no
Inventor
Sidney Edward Callander
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of NO953598D0 publication Critical patent/NO953598D0/no
Publication of NO953598L publication Critical patent/NO953598L/no
Publication of NO306717B1 publication Critical patent/NO306717B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO953598A 1993-03-13 1995-09-12 Fremgangsmåte for fremstilling av piperidin-karbinoler NO306717B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939305175A GB9305175D0 (en) 1993-03-13 1993-03-13 Novel process
PCT/EP1994/000694 WO1994021609A1 (en) 1993-03-13 1994-03-08 Process for preparing acryl-piperidine carbinols

Publications (3)

Publication Number Publication Date
NO953598D0 NO953598D0 (no) 1995-09-12
NO953598L NO953598L (no) 1995-09-12
NO306717B1 true NO306717B1 (no) 1999-12-13

Family

ID=10731995

Family Applications (1)

Application Number Title Priority Date Filing Date
NO953598A NO306717B1 (no) 1993-03-13 1995-09-12 Fremgangsmåte for fremstilling av piperidin-karbinoler

Country Status (27)

Country Link
US (1) US5681962A (cs)
EP (1) EP0688317B1 (cs)
JP (1) JPH08507540A (cs)
KR (1) KR100296719B1 (cs)
CN (2) CN1041918C (cs)
AP (1) AP452A (cs)
AT (1) ATE207898T1 (cs)
AU (1) AU682497B2 (cs)
BR (1) BR9406035A (cs)
CA (1) CA2158175A1 (cs)
CZ (1) CZ235595A3 (cs)
DE (1) DE69428886T2 (cs)
DZ (1) DZ1758A1 (cs)
ES (1) ES2164700T3 (cs)
FI (1) FI954272A7 (cs)
GB (1) GB9305175D0 (cs)
HU (1) HUT72087A (cs)
IL (1) IL108946A (cs)
MA (1) MA23134A1 (cs)
NO (1) NO306717B1 (cs)
NZ (1) NZ262735A (cs)
PH (1) PH31434A (cs)
PL (1) PL176907B1 (cs)
RU (1) RU2141477C1 (cs)
SK (1) SK281977B6 (cs)
WO (1) WO1994021609A1 (cs)
ZA (1) ZA941716B (cs)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6444190B2 (en) 1995-08-03 2002-09-03 Fmc Corporation Reduction compositions and processes for making the same
ES2121685B1 (es) * 1996-04-10 1999-09-16 Vita Invest Sa Procedimiento para la obtencion de (+)-trans-4(4-fluoro-fenil)-3-hidroximetil-1-metilpiperidina.
JP3446468B2 (ja) 1996-04-15 2003-09-16 旭硝子株式会社 ピペリジンカルビノール類の製造方法
US5936090A (en) * 1996-05-24 1999-08-10 Fmc Corporation Processes for the reduction of imide ester functionality
EP1394160A1 (en) 1996-06-13 2004-03-03 SUMIKA FINE CHEMICALS Co., Ltd. Process for preparing crystalline paroxetin hydrochloride
GB9623359D0 (en) * 1996-11-09 1997-01-08 Smithkline Beecham Plc Novel process
GB9710004D0 (en) * 1997-05-17 1997-07-09 Knoll Ag Chemical process
EP0986389B1 (en) * 1997-05-29 2004-10-13 Smithkline Beecham Corporation Novel process
ES2149687B1 (es) * 1998-04-08 2001-05-16 Medichem Sa Procedimiento de obtencion de (+-)-trans-4-(4-fluorofenil)-3-hidroximetilpiperidinas e intermedios de sintesis para las mismas.
GB0003232D0 (en) * 2000-02-11 2000-04-05 Smithkline Beecham Plc Novel composition
TWI232858B (en) * 2000-08-11 2005-05-21 Ono Pharmaceutical Co Piperidine derivatives and pharmaceutical compositions containing such derivatives as an effective ingredient
US6720003B2 (en) * 2001-02-16 2004-04-13 Andrx Corporation Serotonin reuptake inhibitor formulations
ATE392410T1 (de) * 2001-09-14 2008-05-15 Medichem Sa Zwischenprodukte für die herstellung von mirtazapin und verfahren zu deren herstellung
JP5165951B2 (ja) * 2006-07-24 2013-03-21 住友化学株式会社 （±）−トランス−４−（４−フルオロフェニル）−３−ヒドロキシメチルピペリジンの製造方法
WO2008013248A1 (en) * 2006-07-24 2008-01-31 Sumitomo Chemical Company, Limited Process for production of (±)-trans-4-(4- fluorophenyl)-3-hydroxymethylpiperidine
CN109020872B (zh) * 2018-06-26 2020-05-12 浙江邦富生物科技有限责任公司 一种盐酸帕罗西汀关键中间体的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) * 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
JPS5470262A (en) * 1977-11-09 1979-06-05 Daiichi Kagaku Yakuhin Kk Manufacture of pyrrolidinee22methanol
FR2581242B1 (fr) * 1985-04-24 1988-08-26 Telemecanique Electrique Dispositif de commande electrique adaptable a un dispositif de commutation a deux etats
EP0223334B1 (en) * 1985-08-10 1991-07-10 Beecham Group Plc Process for the preparation of aryl-piperidine carbinols
DK716088D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Reduktion af piperidin-dion-derivater samt intermediat
US5258517A (en) * 1992-08-06 1993-11-02 Sepracor, Inc. Method of preparing optically pure precursors of paroxetine

Also Published As

Publication number Publication date
HUT72087A (en) 1996-03-28
PH31434A (en) 1998-11-03
CN1203226A (zh) 1998-12-30
SK281977B6 (sk) 2001-09-11
IL108946A0 (en) 1994-06-24
AP452A (en) 1996-01-19
KR100296719B1 (ko) 2001-10-24
FI954272L (fi) 1995-09-12
CN1041918C (zh) 1999-02-03
CN1055470C (zh) 2000-08-16
FI954272A0 (fi) 1995-09-12
CZ235595A3 (en) 1996-01-17
AP9400624A0 (en) 1994-04-30
FI954272A7 (fi) 1995-09-12
DZ1758A1 (fr) 2002-02-17
EP0688317B1 (en) 2001-10-31
ZA941716B (en) 1995-01-13
RU2141477C1 (ru) 1999-11-20
AU6258794A (en) 1994-10-11
IL108946A (en) 1997-11-20
CN1119012A (zh) 1996-03-20
GB9305175D0 (en) 1993-04-28
BR9406035A (pt) 1996-01-02
DE69428886D1 (de) 2001-12-06
EP0688317A1 (en) 1995-12-27
WO1994021609A1 (en) 1994-09-29
ES2164700T3 (es) 2002-03-01
NO953598D0 (no) 1995-09-12
AU682497B2 (en) 1997-10-09
DE69428886T2 (de) 2002-04-25
CA2158175A1 (en) 1994-09-29
PL176907B1 (pl) 1999-08-31
US5681962A (en) 1997-10-28
PL310469A1 (en) 1995-12-11
ATE207898T1 (de) 2001-11-15
JPH08507540A (ja) 1996-08-13
SK114095A3 (en) 1996-01-10
NZ262735A (en) 1996-10-28
NO953598L (no) 1995-09-12
MA23134A1 (fr) 1994-10-01

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Legal Events

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MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN SEPTEMBER 2003