NO307926B1 - Chalkoner og estere derav med antiproliferativ aktivitet i uterus, ovarie- og brysttumorer - Google Patents

Chalkoner og estere derav med antiproliferativ aktivitet i uterus, ovarie- og brysttumorer

Info

Publication number
NO307926B1
NO307926B1 NO972842A NO972842A NO307926B1 NO 307926 B1 NO307926 B1 NO 307926B1 NO 972842 A NO972842 A NO 972842A NO 972842 A NO972842 A NO 972842A NO 307926 B1 NO307926 B1 NO 307926B1
Authority
NO
Norway
Prior art keywords
pct
uterus
chalcones
esters
antiproliferative activity
Prior art date
Application number
NO972842A
Other languages
English (en)
Norwegian (no)
Other versions
NO972842D0 (no
NO972842L (no
Inventor
Ezio Bombardelli
Salvatore Mancuso
Franco Delle Monache
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of NO972842D0 publication Critical patent/NO972842D0/no
Publication of NO972842L publication Critical patent/NO972842L/no
Publication of NO307926B1 publication Critical patent/NO307926B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/017—Esters of hydroxy compounds having the esterified hydroxy group bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
NO972842A 1994-12-20 1997-06-19 Chalkoner og estere derav med antiproliferativ aktivitet i uterus, ovarie- og brysttumorer NO307926B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI942568A IT1271301B (it) 1994-12-20 1994-12-20 Calconi naturali e sintetici e loro esteri ad attivita' antiproliferativa nei tumori dell'utero,dell'ovaio e del seno e formulazioni che li contengono
PCT/EP1995/004770 WO1996019209A1 (fr) 1994-12-20 1995-12-04 Chalcones et leurs esters a activite antiproliferative dans les tumeurs de l'uterus, de l'ovaire et du sein

Publications (3)

Publication Number Publication Date
NO972842D0 NO972842D0 (no) 1997-06-19
NO972842L NO972842L (no) 1997-06-19
NO307926B1 true NO307926B1 (no) 2000-06-19

Family

ID=11370023

Family Applications (1)

Application Number Title Priority Date Filing Date
NO972842A NO307926B1 (no) 1994-12-20 1997-06-19 Chalkoner og estere derav med antiproliferativ aktivitet i uterus, ovarie- og brysttumorer

Country Status (22)

Country Link
US (1) US5808137A (fr)
EP (1) EP0800387B1 (fr)
JP (1) JP2004131509A (fr)
KR (1) KR100264369B1 (fr)
CN (1) CN1087609C (fr)
AT (1) ATE222756T1 (fr)
AU (1) AU689357B2 (fr)
CA (1) CA2208351C (fr)
CZ (1) CZ288043B6 (fr)
DE (1) DE69527980T2 (fr)
DK (1) DK0800387T3 (fr)
ES (1) ES2181806T3 (fr)
FI (1) FI972641A7 (fr)
HU (1) HU225501B1 (fr)
IT (1) IT1271301B (fr)
NO (1) NO307926B1 (fr)
PL (1) PL183772B1 (fr)
PT (1) PT800387E (fr)
RU (1) RU2181284C2 (fr)
SI (1) SI9520139B (fr)
SK (1) SK282259B6 (fr)
WO (1) WO1996019209A1 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9712966D0 (en) * 1997-06-19 1997-08-27 Indena Spa Novel chalcones
US6423740B1 (en) 1997-06-19 2002-07-23 Indena S.P.A. Chalcones having antiproliferative activity
US6239114B1 (en) * 1997-09-26 2001-05-29 Kgk Synergize Compositions and methods for treatment of neoplastic diseases with combinations of limonoids, flavonoids and tocotrienols
GB9920910D0 (en) * 1999-09-03 1999-11-10 Indena Spa Novel chalcones
GB9920908D0 (en) 1999-09-03 1999-11-10 Indena Spa Chalcone coumarins
US6608101B1 (en) 2000-06-20 2003-08-19 Atherogenics, Inc. 1, 3-bis-(substituted-phenyl)-2-propen-1-ones and their use to treat VCAM-1 mediated disorders
CA2428753C (fr) 2000-11-17 2013-05-21 Universita Degli Studi Di Cagliari Procedes d'inhibition de la transmission du vih au moyen de 6-benzyl-4-oxopyrimidines substituees a application topique
IL162533A0 (en) * 2001-12-19 2005-11-20 Atherogenics Inc Chalcone derivatives and their use to treat diseases
US7514579B2 (en) 2002-06-13 2009-04-07 Johns Hopkins University Boronic chalcone derivatives and uses thereof
WO2004056727A2 (fr) * 2002-12-19 2004-07-08 Atherogenics, Inc. Procede de fabrication de derives de chalcone
JPWO2005054170A1 (ja) 2003-12-05 2007-12-06 タカラバイオ株式会社 治療剤
WO2006004903A2 (fr) * 2004-06-28 2006-01-12 Atherogenics, Inc. 1,2-bis-(phenyl-substitue)-2-propen-1-ones et des compositions pharmaceutiques en contenant
CN100336797C (zh) * 2005-08-19 2007-09-12 浙江大学 四取代查耳酮衍生物及制备方法和用途
GB0609386D0 (en) * 2006-05-11 2006-06-21 Active Botan Ltd Treating drug resistant cancers
US9132117B2 (en) 2013-06-17 2015-09-15 Kgk Synergize, Inc Compositions and methods for glycemic control of subjects with impaired fasting glucose
ES2540457B2 (es) * 2013-06-19 2015-12-28 Universidad De Sevilla Procedimiento de obtención de extractos de hojas de Corema album y su aplicación terapéutica
KR101731159B1 (ko) 2015-02-04 2017-04-28 계명대학교 산학협력단 2',4'-디하이드록시칼콘 화합물을 유효성분으로 포함하는 항진균용 조성물
CZ307046B6 (cs) * 2015-09-02 2017-12-13 Univerzita PalackĂ©ho v Olomouci Komplexy mědi s deriváty (E)-1-(2´-hydroxyfenyl)-3-fenylprop-2-en-1-onu a jejich použití jako léčiv v protinádorové terapii
CN111138264B (zh) * 2019-11-29 2023-08-04 温州医科大学 一种丁香醛衍生物及其在制备抗妇科肿瘤药物中的应用
CN113564103B (zh) * 2021-05-17 2023-01-06 南京医科大学 4,4’-二甲氧基查耳酮在延缓卵母细胞体内外老化中的应用
CN119552068A (zh) * 2024-11-29 2025-03-04 华东理工大学 查尔酮类衍生物、其药物组合物及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH593224A5 (fr) * 1973-10-30 1977-11-30 Taisho Pharmaceutical Co Ltd
US5234951A (en) * 1986-12-12 1993-08-10 Tsumura Juntendo, Inc. Anti-ulcer agent comprising chalcone derivative
EP0292576A4 (en) * 1986-12-12 1990-10-03 Tsumura Juntendo, Inc. Anti-ulcerous agent containing chalcone derivative as effective ingredient and novel chalcone derivatives
AU7963691A (en) * 1990-05-17 1991-12-10 Baylor College Of Medicine Growth inhibitors and methods of treating cancer and cell proliferative diseases
AU2393992A (en) * 1991-07-24 1993-02-23 Baylor College Of Medicine Combination therapy using bioflavonoid compounds with anti-cancer drugs

Also Published As

Publication number Publication date
FI972641A0 (fi) 1997-06-19
RU2181284C2 (ru) 2002-04-20
DE69527980D1 (de) 2002-10-02
HUT77438A (hu) 1998-04-28
CA2208351A1 (fr) 1996-06-27
AU4301996A (en) 1996-07-10
SK78197A3 (en) 1997-12-10
CN1087609C (zh) 2002-07-17
ITMI942568A0 (it) 1994-12-20
SI9520139B (sl) 1999-02-28
NO972842D0 (no) 1997-06-19
KR100264369B1 (ko) 2000-08-16
ITMI942568A1 (it) 1996-06-20
ATE222756T1 (de) 2002-09-15
JP2004131509A (ja) 2004-04-30
IT1271301B (it) 1997-05-27
PL320787A1 (en) 1997-10-27
DE69527980T2 (de) 2003-05-28
SI9520139A (en) 1997-10-31
PT800387E (pt) 2002-12-31
EP0800387A1 (fr) 1997-10-15
EP0800387B1 (fr) 2002-08-28
DK0800387T3 (da) 2002-12-23
US5808137A (en) 1998-09-15
CA2208351C (fr) 2002-06-25
CZ186997A3 (en) 1997-11-12
ES2181806T3 (es) 2003-03-01
FI972641L (fi) 1997-08-14
NO972842L (no) 1997-06-19
FI972641A7 (fi) 1997-08-14
AU689357B2 (en) 1998-03-26
CZ288043B6 (cs) 2001-04-11
SK282259B6 (sk) 2001-12-03
HU225501B1 (en) 2007-01-29
PL183772B1 (pl) 2002-07-31
CN1170362A (zh) 1998-01-14
WO1996019209A1 (fr) 1996-06-27

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