NO312492B1 - Anvendelse av 1-hydroksy-2-pyridoner til behandling av sebor±isk dermatitt - Google Patents

Anvendelse av 1-hydroksy-2-pyridoner til behandling av sebor±isk dermatitt Download PDF

Info

Publication number: NO312492B1
Authority: NO; Norway
Prior art keywords: hydroxy; formula; use according; pyridone; atoms
Prior art date: 1996-09-27

Application number

NO19991460A

Other languages

English (en)

Norwegian (no)

Other versions

NO991460D0 (no

NO991460L (no

Inventor

Manfred Bohn

Karl Theodor Kraemer

Astrid Markus

Original Assignee

Aventis Pharma Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-09-27

Filing date

1999-03-25

Publication date

2002-05-21

1999-03-25 Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh

1999-03-25 Publication of NO991460D0 publication Critical patent/NO991460D0/no

1999-03-25 Publication of NO991460L publication Critical patent/NO991460L/no

2002-05-21 Publication of NO312492B1 publication Critical patent/NO312492B1/no

Links

238000011282 treatment Methods 0.000 title claims description 8
SNUSZUYTMHKCPM-UHFFFAOYSA-N 1-hydroxypyridin-2-one Chemical class ON1C=CC=CC1=O SNUSZUYTMHKCPM-UHFFFAOYSA-N 0.000 title claims description 6
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238000002360 preparation method Methods 0.000 claims description 35
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125000004432 carbon atom Chemical group C* 0.000 claims description 10
206010039793 Seborrhoeic dermatitis Diseases 0.000 claims description 9
208000008742 seborrheic dermatitis Diseases 0.000 claims description 9
239000002280 amphoteric surfactant Chemical group 0.000 claims description 8
125000000217 alkyl group Chemical group 0.000 claims description 6
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229910052717 sulfur Inorganic materials 0.000 claims description 5
125000004434 sulfur atom Chemical group 0.000 claims description 5
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims description 4
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims description 4
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 4
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims description 4
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WOWHHFRSBJGXCM-UHFFFAOYSA-M cetyltrimethylammonium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+](C)(C)C WOWHHFRSBJGXCM-UHFFFAOYSA-M 0.000 description 1
229960003749 ciclopirox Drugs 0.000 description 1
229920001436 collagen Polymers 0.000 description 1
239000007859 condensation product Substances 0.000 description 1
230000036758 dandruff formation Effects 0.000 description 1
238000003745 diagnosis Methods 0.000 description 1
ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 description 1
238000010790 dilution Methods 0.000 description 1
239000012895 dilution Substances 0.000 description 1
NAPSCFZYZVSQHF-UHFFFAOYSA-N dimantine Chemical compound CCCCCCCCCCCCCCCCCCN(C)C NAPSCFZYZVSQHF-UHFFFAOYSA-N 0.000 description 1
229950010007 dimantine Drugs 0.000 description 1
SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 description 1
LTYMSROWYAPPGB-UHFFFAOYSA-N diphenyl sulfide Chemical class C=1C=CC=CC=1SC1=CC=CC=C1 LTYMSROWYAPPGB-UHFFFAOYSA-N 0.000 description 1
208000035475 disorder Diseases 0.000 description 1
239000006185 dispersion Chemical class 0.000 description 1
JRBPAEWTRLWTQC-UHFFFAOYSA-N dodecylamine Chemical compound CCCCCCCCCCCCN JRBPAEWTRLWTQC-UHFFFAOYSA-N 0.000 description 1
229940079593 drug Drugs 0.000 description 1
239000003814 drug Substances 0.000 description 1
239000000975 dye Substances 0.000 description 1
235000014103 egg white Nutrition 0.000 description 1
210000000969 egg white Anatomy 0.000 description 1
UYMKPFRHYYNDTL-UHFFFAOYSA-N ethenamine Chemical compound NC=C UYMKPFRHYYNDTL-UHFFFAOYSA-N 0.000 description 1
125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
210000000744 eyelid Anatomy 0.000 description 1
239000003925 fat Substances 0.000 description 1
239000006260 foam Substances 0.000 description 1
238000005187 foaming Methods 0.000 description 1
210000001061 forehead Anatomy 0.000 description 1
239000003205 fragrance Substances 0.000 description 1
230000002538 fungal effect Effects 0.000 description 1
210000003128 head Anatomy 0.000 description 1
MTNDZQHUAFNZQY-UHFFFAOYSA-N imidazoline Chemical compound C1CN=CN1 MTNDZQHUAFNZQY-UHFFFAOYSA-N 0.000 description 1
125000003454 indenyl group Chemical group C1(C=CC2=CC=CC=C12)* 0.000 description 1
208000015181 infectious disease Diseases 0.000 description 1
229910001411 inorganic cation Inorganic materials 0.000 description 1
SHLPPXXKRFINFY-UHFFFAOYSA-N isoquinolin-2-ium;bromide Chemical compound Br.C1=NC=CC2=CC=CC=C21 SHLPPXXKRFINFY-UHFFFAOYSA-N 0.000 description 1
230000001530 keratinolytic effect Effects 0.000 description 1
239000004310 lactic acid Substances 0.000 description 1
235000014655 lactic acid Nutrition 0.000 description 1
ISWNAMNOYHCTSB-UHFFFAOYSA-N methanamine;hydrobromide Chemical compound [Br-].[NH3+]C ISWNAMNOYHCTSB-UHFFFAOYSA-N 0.000 description 1
CRVGTESFCCXCTH-UHFFFAOYSA-N methyl diethanolamine Chemical compound OCCN(C)CCO CRVGTESFCCXCTH-UHFFFAOYSA-N 0.000 description 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 description 1
125000000325 methylidene group Chemical group [H]C([H])=* 0.000 description 1
210000003097 mucus Anatomy 0.000 description 1
YWFWDNVOPHGWMX-UHFFFAOYSA-N n,n-dimethyldodecan-1-amine Chemical compound CCCCCCCCCCCCN(C)C YWFWDNVOPHGWMX-UHFFFAOYSA-N 0.000 description 1
HVAAHUDGWQAAOJ-UHFFFAOYSA-N n-benzylethanamine Chemical compound CCNCC1=CC=CC=C1 HVAAHUDGWQAAOJ-UHFFFAOYSA-N 0.000 description 1
125000001624 naphthyl group Chemical group 0.000 description 1
229920001206 natural gum Polymers 0.000 description 1
210000001331 nose Anatomy 0.000 description 1
239000003921 oil Substances 0.000 description 1
JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 description 1
125000001117 oleyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])/C([H])=C([H])\C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
238000005457 optimization Methods 0.000 description 1
150000007524 organic acids Chemical class 0.000 description 1
235000005985 organic acids Nutrition 0.000 description 1
150000007530 organic bases Chemical class 0.000 description 1
FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
235000021317 phosphate Nutrition 0.000 description 1
201000000508 pityriasis versicolor Diseases 0.000 description 1
229920001983 poloxamer Polymers 0.000 description 1
229920000642 polymer Polymers 0.000 description 1
229920005862 polyol Polymers 0.000 description 1
150000003077 polyols Chemical class 0.000 description 1
229920001451 polypropylene glycol Polymers 0.000 description 1
229920001296 polysiloxane Polymers 0.000 description 1
235000007686 potassium Nutrition 0.000 description 1
BBFCIBZLAVOLCF-UHFFFAOYSA-N pyridin-1-ium;bromide Chemical compound Br.C1=CC=NC=C1 BBFCIBZLAVOLCF-UHFFFAOYSA-N 0.000 description 1
GGOZGYRTNQBSSA-UHFFFAOYSA-N pyridine-2,3-diol Chemical class OC1=CC=CN=C1O GGOZGYRTNQBSSA-UHFFFAOYSA-N 0.000 description 1
125000001453 quaternary ammonium group Chemical group 0.000 description 1
150000003242 quaternary ammonium salts Chemical class 0.000 description 1
229960004889 salicylic acid Drugs 0.000 description 1
235000015424 sodium Nutrition 0.000 description 1
159000000000 sodium salts Chemical class 0.000 description 1
229910052938 sodium sulfate Inorganic materials 0.000 description 1
235000011152 sodium sulphate Nutrition 0.000 description 1
239000007787 solid Substances 0.000 description 1
239000000243 solution Substances 0.000 description 1
239000007921 spray Substances 0.000 description 1
125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
125000001424 substituent group Chemical group 0.000 description 1
150000003445 sucroses Chemical class 0.000 description 1
AGGIJOLULBJGTQ-UHFFFAOYSA-N sulfoacetic acid Chemical compound OC(=O)CS(O)(=O)=O AGGIJOLULBJGTQ-UHFFFAOYSA-N 0.000 description 1
125000001273 sulfonato group Chemical class [O-]S(*)(=O)=O 0.000 description 1
150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
208000024891 symptom Diseases 0.000 description 1
229940073455 tetraethylammonium hydroxide Drugs 0.000 description 1
LRGJRHZIDJQFCL-UHFFFAOYSA-M tetraethylazanium;hydroxide Chemical compound [OH-].CC[N+](CC)(CC)CC LRGJRHZIDJQFCL-UHFFFAOYSA-M 0.000 description 1
125000001712 tetrahydronaphthyl group Chemical group C1(CCCC2=CC=CC=C12)* 0.000 description 1
238000002560 therapeutic procedure Methods 0.000 description 1
230000008719 thickening Effects 0.000 description 1
239000002562 thickening agent Substances 0.000 description 1
238000011200 topical administration Methods 0.000 description 1
IMFACGCPASFAPR-UHFFFAOYSA-N tributylamine Chemical compound CCCCN(CCCC)CCCC IMFACGCPASFAPR-UHFFFAOYSA-N 0.000 description 1
GSEJCLTVZPLZKY-UHFFFAOYSA-O triethanolammonium Chemical compound OCC[NH+](CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-O 0.000 description 1
241001148471 unidentified anaerobic bacterium Species 0.000 description 1
230000003442 weekly effect Effects 0.000 description 1
238000009736 wetting Methods 0.000 description 1
150000003751 zinc Chemical class 0.000 description 1
229910052725 zinc Inorganic materials 0.000 description 1
239000011701 zinc Substances 0.000 description 1
150000003754 zirconium Chemical class 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Dermatology (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Birds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cosmetics (AREA)
Pyridine Compounds (AREA)

NO19991460A 1996-09-27 1999-03-25 Anvendelse av 1-hydroksy-2-pyridoner til behandling av sebor±isk dermatitt NO312492B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19639818A DE19639818A1 (de)	1996-09-27	1996-09-27	Verwendung von 1-Hydroxy-2-pyridonen zur Behandlung der Seborrhoischen Dermatitis
PCT/EP1997/005070 WO1998013009A2 (de)	1996-09-27	1997-09-16	Verwendung von 1-hydroxy-2-pyridonen zur behandlung der seborrhoischen dermatitis

Publications (3)

Publication Number	Publication Date
NO991460D0 NO991460D0 (no)	1999-03-25
NO991460L NO991460L (no)	1999-03-25
NO312492B1 true NO312492B1 (no)	2002-05-21

Family

ID=7807118

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19991460A NO312492B1 (no)	1996-09-27	1999-03-25	Anvendelse av 1-hydroksy-2-pyridoner til behandling av sebor±isk dermatitt

Country Status (31)

Country	Link
EP (1)	EP0928183B1 (pl)
JP (2)	JP2001500884A (pl)
KR (1)	KR100494207B1 (pl)
CN (1)	CN1104231C (pl)
AR (1)	AR008860A1 (pl)
AT (1)	ATE209891T1 (pl)
AU (1)	AU716208B2 (pl)
BG (1)	BG64365B1 (pl)
BR (1)	BR9711575A (pl)
CA (1)	CA2267165C (pl)
CY (1)	CY2362B1 (pl)
CZ (1)	CZ291485B6 (pl)
DE (2)	DE19639818A1 (pl)
DK (1)	DK0928183T3 (pl)
ES (1)	ES2167721T3 (pl)
HU (1)	HU226955B1 (pl)
ID (1)	ID21874A (pl)
IL (1)	IL129141A0 (pl)
MA (1)	MA24333A1 (pl)
MY (1)	MY125674A (pl)
NO (1)	NO312492B1 (pl)
NZ (1)	NZ334850A (pl)
OA (1)	OA11028A (pl)
PL (1)	PL188033B1 (pl)
PT (1)	PT928183E (pl)
RS (1)	RS49801B (pl)
TR (1)	TR199900662T2 (pl)
TW (1)	TW519491B (pl)
UA (1)	UA57754C2 (pl)
WO (1)	WO1998013009A2 (pl)
ZA (1)	ZA978640B (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20040039030A1 (en)	1996-09-27	2004-02-26	Hoechst Akeengesellschaft	Use of 1-hydroxy-2-pyridones for the treatment of seborrheic dermatitis
DE19639816A1 (de)	1996-09-27	1998-04-02	Hoechst Ag	Antimykotische Mittel mit hoher Wirkstofffreisetzung
US20050095215A1 (en) *	2003-11-03	2005-05-05	Popp Karl F.	Antimicrobial shampoo compositions
EP2197440B1 (en)	2007-08-31	2012-12-26	Janssen Pharmaceutica, N.V.	Combinations of imazalil and hydroxypyridones
NZ585433A (en)	2007-11-30	2011-11-25	Janssen Pharmaceutica Nv	Combinations of fungicidal azoles and pyrion compounds
EP2252147B1 (en)	2008-02-06	2012-12-05	Janssen Pharmaceutica NV	Combinations of fludioxonil and pyrion compounds
EP2587920B1 (en)	2010-07-01	2016-08-10	Janssen Pharmaceutica, N.V.	Antimicrobial combinations of pyrion compounds with polyethyleneimines
ES2573116T3 (es) *	2010-12-02	2016-06-06	The University Of Kansas	Profármacos de 6-ciclohexil-1-hidroxi-4-metilpiridin-2(1H)-ona y sus derivados
JP5528629B2 (ja) *	2011-07-19	2014-06-25	リジェンティス株式会社	酵母菌から抽出されたポリリン酸，ポリリン酸の塩又はポリリン酸の溶媒和物を含むポリリン酸組成物及びその製造方法。
FR2983858B1 (fr) *	2011-12-08	2014-01-03	Fabre Pierre Dermo Cosmetique	Nouveaux composes inhibiteurs de la lipogenese
CN104744359B (zh) *	2015-03-06	2017-10-10	上药康丽（常州）药业有限公司	一种环吡酮的精制方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2234009C3 (de) *	1972-07-11	1979-01-11	Hoechst Ag, 6000 Frankfurt	Kosmetische Zubereitungen
NL8601762A (nl) *	1986-07-07	1988-02-01	Bouke Jan Lange	Werkwijze voor de reiniging en conditionering en eventuele medicinale behandeling van het haar en de hoofdhuid, een voor dit doel bruikbare tweefasen shampoo, alsmede een verpakking daarvoor.
KR950702819A (ko) *	1992-09-08	1995-08-23	제이코버스 코넬리스 레이서	실질적으로 무색의 순한 샴푸 조성물(mild, substantially coloriess shampoo compostion)
DE4333893A1 (de) *	1993-10-05	1995-04-06	Hoechst Ag	Kosmetische Zubereitungen
FR2722689B1 (fr) *	1994-07-20	1996-10-04	Fabre Pierre Dermo Cosmetique	Nouveau produit de combinaison comprenant un agent antifongique et du crotamiton comme potentialisateur de l'activite de l'agent antifongique, et compositions dermatologiques et/ou cosmetiques le comprenant

1996
- 1996-09-27 DE DE19639818A patent/DE19639818A1/de not_active Withdrawn
1997
- 1997-09-16 AT AT97910294T patent/ATE209891T1/de active
- 1997-09-16 KR KR10-1999-7002553A patent/KR100494207B1/ko not_active Expired - Lifetime
- 1997-09-16 HU HU9903811A patent/HU226955B1/hu unknown
- 1997-09-16 JP JP10515223A patent/JP2001500884A/ja active Pending
- 1997-09-16 ID IDW990129A patent/ID21874A/id unknown
- 1997-09-16 CZ CZ19991075A patent/CZ291485B6/cs not_active IP Right Cessation
- 1997-09-16 CN CN97198266A patent/CN1104231C/zh not_active Expired - Lifetime
- 1997-09-16 ES ES97910294T patent/ES2167721T3/es not_active Expired - Lifetime
- 1997-09-16 CA CA002267165A patent/CA2267165C/en not_active Expired - Lifetime
- 1997-09-16 PT PT97910294T patent/PT928183E/pt unknown
- 1997-09-16 DE DE59705697T patent/DE59705697D1/de not_active Expired - Lifetime
- 1997-09-16 RS YUP-134/99A patent/RS49801B/sr unknown
- 1997-09-16 BR BR9711575A patent/BR9711575A/pt not_active Application Discontinuation
- 1997-09-16 TR TR1999/00662T patent/TR199900662T2/xx unknown
- 1997-09-16 NZ NZ334850A patent/NZ334850A/en not_active IP Right Cessation
- 1997-09-16 EP EP97910294A patent/EP0928183B1/de not_active Expired - Lifetime
- 1997-09-16 UA UA99042351A patent/UA57754C2/uk unknown
- 1997-09-16 IL IL12914197A patent/IL129141A0/xx not_active IP Right Cessation
- 1997-09-16 AU AU47746/97A patent/AU716208B2/en not_active Expired
- 1997-09-16 DK DK97910294T patent/DK0928183T3/da active
- 1997-09-16 WO PCT/EP1997/005070 patent/WO1998013009A2/de not_active Ceased
- 1997-09-16 PL PL33260397A patent/PL188033B1/pl unknown
- 1997-09-25 AR ARP970104432A patent/AR008860A1/es not_active Application Discontinuation
- 1997-09-25 TW TW086113944A patent/TW519491B/zh not_active IP Right Cessation
- 1997-09-26 MY MYPI97004501A patent/MY125674A/en unknown
- 1997-09-26 ZA ZA9708640A patent/ZA978640B/xx unknown
- 1997-09-29 MA MA24814A patent/MA24333A1/fr unknown
1999
- 1999-03-17 BG BG103260A patent/BG64365B1/bg unknown
- 1999-03-25 NO NO19991460A patent/NO312492B1/no not_active IP Right Cessation
- 1999-03-26 OA OA9900071A patent/OA11028A/fr unknown
2003
- 2003-05-26 CY CY0300044A patent/CY2362B1/xx unknown
2006
- 2006-03-22 JP JP2006078057A patent/JP2006176540A/ja not_active Abandoned

Also Published As

Publication number	Publication date
ES2167721T3 (es)	2002-05-16
ATE209891T1 (de)	2001-12-15
CY2362B1 (en)	2004-06-04
NO991460D0 (no)	1999-03-25
BR9711575A (pt)	1999-08-24
CZ107599A3 (cs)	1999-06-16
WO1998013009A2 (de)	1998-04-02
HK1022267A1 (en)	2000-08-04
HUP9903811A1 (hu)	2000-04-28
CZ291485B6 (cs)	2003-03-12
DK0928183T3 (da)	2002-04-02
RS49801B (sr)	2008-06-05
DE59705697D1 (de)	2002-01-17
HU226955B1 (en)	2010-03-29
ZA978640B (en)	1998-03-27
PT928183E (pt)	2002-05-31
CN1104231C (zh)	2003-04-02
CA2267165C (en)	2003-12-16
JP2001500884A (ja)	2001-01-23
MA24333A1 (fr)	1998-04-01
WO1998013009A3 (de)	1998-05-14
EP0928183A2 (de)	1999-07-14
PL188033B1 (pl)	2004-11-30
AR008860A1 (es)	2000-02-23
CN1231595A (zh)	1999-10-13
AU716208B2 (en)	2000-02-24
HUP9903811A3 (en)	2001-11-28
OA11028A (fr)	2003-03-06
KR100494207B1 (ko)	2005-06-13
NO991460L (no)	1999-03-25
BG103260A (en)	2000-01-31
UA57754C2 (uk)	2003-07-15
NZ334850A (en)	2001-02-23
TR199900662T2 (xx)	1999-06-21
DE19639818A1 (de)	1998-04-02
EP0928183B1 (de)	2001-12-05
PL332603A1 (en)	1999-09-27
JP2006176540A (ja)	2006-07-06
AU4774697A (en)	1998-04-17
YU13499A (sh)	2001-09-28
MY125674A (en)	2006-08-30
IL129141A0 (en)	2000-02-17
CA2267165A1 (en)	1998-04-02
TW519491B (en)	2003-02-01
ID21874A (id)	1999-08-05
BG64365B1 (bg)	2004-12-30
KR20000048613A (ko)	2000-07-25

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Publication	Publication Date	Title
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JPS6220167B2 (pl)	1987-05-06
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