NO312708B1 - Radioaktive liposomer til terapi - Google Patents
Radioaktive liposomer til terapi Download PDFInfo
- Publication number
- NO312708B1 NO312708B1 NO20000855A NO20000855A NO312708B1 NO 312708 B1 NO312708 B1 NO 312708B1 NO 20000855 A NO20000855 A NO 20000855A NO 20000855 A NO20000855 A NO 20000855A NO 312708 B1 NO312708 B1 NO 312708B1
- Authority
- NO
- Norway
- Prior art keywords
- liposomes
- stated
- composition
- radionuclide
- solution
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
- A61K51/1072—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from the reproductive system, e.g. ovaria, uterus, testes or prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
- A61K51/1234—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dispersion Chemistry (AREA)
- Reproductive Health (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Priority Applications (22)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO20000855A NO312708B1 (no) | 2000-02-21 | 2000-02-21 | Radioaktive liposomer til terapi |
| CA002400994A CA2400994C (en) | 2000-02-21 | 2001-02-21 | Radioactive therapeutic liposomes |
| AT01910251T ATE300316T1 (de) | 2000-02-21 | 2001-02-21 | Radioaktive therapeutische liposomen |
| ES01910251T ES2247069T3 (es) | 2000-02-21 | 2001-02-21 | Liposomas terapeuticos radioactivos. |
| NZ520848A NZ520848A (en) | 2000-02-21 | 2001-02-21 | Radioactive therapeutic liposomes |
| JP2001559512A JP4933712B2 (ja) | 2000-02-21 | 2001-02-21 | 放射線治療用リポソーム |
| MXPA02008110A MXPA02008110A (es) | 2000-02-21 | 2001-02-21 | Liposomas terapeuticos radioactivos. |
| EP01910251A EP1257299B9 (en) | 2000-02-21 | 2001-02-21 | Radioactive therapeutic liposomes |
| DE60112251T DE60112251T2 (de) | 2000-02-21 | 2001-02-21 | Radioaktive therapeutische liposomen |
| CZ20023164A CZ299032B6 (cs) | 2000-02-21 | 2001-02-21 | Konjugátorový systém |
| PL358541A PL201398B1 (pl) | 2000-02-21 | 2001-02-21 | System koniugatora radionuklid-liposom, sposób jego wytwarzania, zastosowanie systemu koniugatora do wytwarzania roztworu farmaceutycznego, zastosowanie terapeutyczne systemu koniugatora oraz zestaw do wytwarzania systemu koniugatora |
| CNB018053726A CN100350981C (zh) | 2000-02-21 | 2001-02-21 | 有放射活性的治疗性脂质体 |
| DK01910251T DK1257299T3 (da) | 2000-02-21 | 2001-02-21 | Radioaktive, terapeutiske liposomer |
| EA200200793A EA005624B1 (ru) | 2000-02-21 | 2001-02-21 | Радиоактивные терапевтические липосомы |
| AU3782701A AU3782701A (en) | 2000-02-21 | 2001-02-21 | Radioactive therapeutic liposomes |
| AU2001237827A AU2001237827B2 (en) | 2000-02-21 | 2001-02-21 | Radioactive therapeutic liposomes |
| US09/790,260 US6592843B2 (en) | 2000-02-21 | 2001-02-21 | Radioactive therapeutic liposomes |
| BR0108572-7A BR0108572A (pt) | 2000-02-21 | 2001-02-21 | Sistema conjugador, método para preparar um sistema conjugador radiorrotulado, uso do sistema conjugador, método para utilizar o sistema conjugador, e, kit para a preparação do sistema conjugador |
| KR1020027010848A KR100822566B1 (ko) | 2000-02-21 | 2001-02-21 | 방사성 치료 리포좀 |
| PCT/NO2001/000065 WO2001060417A2 (en) | 2000-02-21 | 2001-02-21 | Radioactive therapeutic liposomes |
| UA2002086850A UA73160C2 (uk) | 2000-02-21 | 2001-02-21 | Кон'югаційна система, що являє собою радіоактивні терапевтичні ліпосоми, спосіб їх одержання та застосування |
| ZA200206500A ZA200206500B (en) | 2000-02-21 | 2002-08-14 | Radioactive therapeutic liposomes. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO20000855A NO312708B1 (no) | 2000-02-21 | 2000-02-21 | Radioaktive liposomer til terapi |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20000855D0 NO20000855D0 (no) | 2000-02-21 |
| NO20000855L NO20000855L (no) | 2001-08-22 |
| NO312708B1 true NO312708B1 (no) | 2002-06-24 |
Family
ID=19910768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20000855A NO312708B1 (no) | 2000-02-21 | 2000-02-21 | Radioaktive liposomer til terapi |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6592843B2 (pl) |
| EP (1) | EP1257299B9 (pl) |
| JP (1) | JP4933712B2 (pl) |
| KR (1) | KR100822566B1 (pl) |
| CN (1) | CN100350981C (pl) |
| AT (1) | ATE300316T1 (pl) |
| AU (2) | AU2001237827B2 (pl) |
| BR (1) | BR0108572A (pl) |
| CA (1) | CA2400994C (pl) |
| CZ (1) | CZ299032B6 (pl) |
| DE (1) | DE60112251T2 (pl) |
| DK (1) | DK1257299T3 (pl) |
| EA (1) | EA005624B1 (pl) |
| ES (1) | ES2247069T3 (pl) |
| MX (1) | MXPA02008110A (pl) |
| NO (1) | NO312708B1 (pl) |
| NZ (1) | NZ520848A (pl) |
| PL (1) | PL201398B1 (pl) |
| UA (1) | UA73160C2 (pl) |
| WO (1) | WO2001060417A2 (pl) |
| ZA (1) | ZA200206500B (pl) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO310544B1 (no) * | 1999-01-04 | 2001-07-23 | Algeta As | Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben |
| NO314537B1 (no) * | 1999-12-06 | 2003-04-07 | Anticancer Therapeutic Inv Sa | Reseptorbindende konjugater |
| US8029795B2 (en) * | 1999-12-30 | 2011-10-04 | Gwathmey, Inc. | Targeted iron chelator delivery system |
| US20040166060A1 (en) * | 2000-06-16 | 2004-08-26 | Sloan Kettering Institute For Cancer Research | Liposomal encapsulation of alpha particle emittors and uses thereof |
| EP1289570B1 (en) * | 2000-06-16 | 2008-09-10 | Sloan-Kettering Institute For Cancer Research | Liposomal encapsulation of alpha-emitters and uses thereof |
| NO313180B1 (no) * | 2000-07-04 | 2002-08-26 | Anticancer Therapeutic Inv Sa | Bensökende alfapartikkel emitterende radiofarmasöytika |
| US6869591B2 (en) * | 2002-03-26 | 2005-03-22 | Barnes-Jewish Hospital | Paramagnetic particles that provide improved relaxivity |
| GB0213261D0 (en) * | 2002-06-10 | 2002-07-17 | Anticancer Therapeutic Inv Sa | Method |
| NZ595758A (en) * | 2003-04-15 | 2013-02-22 | Algeta As | Thorium-227 for use in radiotherapy of soft tissue disease |
| GB0308731D0 (en) * | 2003-04-15 | 2003-05-21 | Anticancer Therapeutic Inv Sa | Method of radiotherapy |
| CN1849112B (zh) * | 2003-09-09 | 2012-06-13 | 吉里德科学公司 | 治疗性脂质体 |
| PL1735013T3 (pl) * | 2004-02-20 | 2012-07-31 | Algeta Asa | Cząstki hydroksyapatytu alfa- i beta-emitujące |
| US20050266067A1 (en) * | 2004-03-02 | 2005-12-01 | Shiladitya Sengupta | Nanocell drug delivery system |
| US20070053845A1 (en) * | 2004-03-02 | 2007-03-08 | Shiladitya Sengupta | Nanocell drug delivery system |
| GB0423565D0 (en) * | 2004-10-22 | 2004-11-24 | Algeta As | Formulation |
| WO2006099445A2 (en) * | 2005-03-14 | 2006-09-21 | Massachusetts Institute Of Technology | Nanocells for diagnosis and treatment of diseases and disorders |
| US8709380B1 (en) * | 2006-02-07 | 2014-04-29 | Sirius Medicine, Llc | Targeting agents for enhancing radiation therapy |
| US20070224115A1 (en) * | 2006-03-22 | 2007-09-27 | The Regents Of The University Of California | Polymeric chelators for radionuclide delivery systems |
| CN101485629B (zh) * | 2008-01-16 | 2013-01-23 | 沈阳药科大学 | 一种给药系统及其制备方法 |
| US20100178245A1 (en) * | 2009-01-13 | 2010-07-15 | Arnsdorf Morton F | Biocompatible Microbubbles to Deliver Radioactive Compounds to Tumors, Atherosclerotic Plaques, Joints and Other Targeted Sites |
| US20100178244A1 (en) * | 2009-01-13 | 2010-07-15 | Arnsdorf Morton F | Biocompatible Microbubbles to Deliver Radioactive Compounds to Tumors, Atherosclerotic Plaques, Joints and Other Targeted Sites |
| WO2010135714A2 (en) | 2009-05-22 | 2010-11-25 | The Methodist Hospital Research Institute | Methods for modulating adipocyte expression using microrna compositions |
| WO2011006510A1 (en) | 2009-07-17 | 2011-01-20 | Technical University Of Denmark | Loading technique for preparing radionuclide and ionophore containing liposomes in which the ionophore is 2-hydroxyquionoline (carbostyril) or structurally related 2-hydroxyquinolines |
| JP2011111438A (ja) * | 2009-11-30 | 2011-06-09 | Akita Univ | 有機金属錯体を有効成分として含有する抗がん剤 |
| GB201002508D0 (en) | 2010-02-12 | 2010-03-31 | Algeta As | Product |
| JP5947807B2 (ja) * | 2010-12-14 | 2016-07-06 | テクニカル ユニバーシティ オブ デンマークTechnical University Of Denmark | ナノ粒子組成物への放射性核種の封入 |
| GB201105298D0 (en) * | 2011-03-29 | 2011-05-11 | Algeta Asa | Pharmaceutical preparation |
| DE102011079031A1 (de) * | 2011-07-12 | 2013-01-17 | Algeta Asa | Flüssigkeitsbehälter |
| GB201208309D0 (en) | 2012-05-11 | 2012-06-27 | Algeta As | Complexes |
| EP2968150B1 (en) * | 2013-03-11 | 2020-08-19 | Wayne State University | Liposomes comprising europium cryptands and their use |
| SG11201706849SA (en) * | 2015-02-26 | 2017-09-28 | Sciencons AS | Radiopharmaceutical solutions with advantageous properties |
| US9433690B1 (en) | 2015-02-26 | 2016-09-06 | Sciencons AS | Radiopharmaceutical solutions with advantageous properties |
| NO3061464T3 (pl) * | 2015-02-26 | 2018-03-24 | ||
| PT3111959T (pt) * | 2015-07-03 | 2017-12-14 | Oncoinvent As | Partículas e suspensões radioterapêuticas |
| SG10202009424TA (en) | 2016-03-24 | 2020-11-27 | Bayer Pharma AG | Radio-pharmaceutical complexes |
| CN109689115A (zh) | 2016-06-10 | 2019-04-26 | 拜耳制药股份公司 | 放射性药物配合物 |
| IL263808B2 (en) * | 2016-06-24 | 2025-04-01 | Sciencons AS | Preparation of 212PB-labeled monoclonal antibodies |
| CN120643844A (zh) | 2017-05-11 | 2025-09-16 | 阿尔法陶医疗有限公司 | 用于近距离放射治疗装置的聚合物涂层 |
| WO2019193464A1 (en) | 2018-04-02 | 2019-10-10 | Alpha Tau Medical Ltd. | Controlled release of radionuclides |
| WO2021013978A1 (en) | 2019-07-25 | 2021-01-28 | Bayer As | Targeted radiopharmaceuticals for the diagnosis and treatment of prostate cancer |
| JP7544819B2 (ja) | 2019-12-05 | 2024-09-03 | サイエンコンス アクスイェ セルスカプ | 高度に精製された212Pbの製造 |
| AU2021400142B2 (en) | 2020-12-16 | 2024-11-21 | Alpha Tau Medical Ltd. | Diffusing alpha-emitters radiation therapy with enhanced beta treatment |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4310506A (en) * | 1979-02-22 | 1982-01-12 | California Institute Of Technology | Means of preparation and applications of liposomes containing high concentrations of entrapped ionic species |
| DK482685D0 (da) * | 1984-10-22 | 1985-10-21 | Hope Nat Medical Center | Fremgangsmaade til tilfoersel af micellulaere partikler, der indkapslerbilleddannende og kemoterapeutiske midler, til tumorer i et legeme |
| CA1314209C (en) * | 1987-11-04 | 1993-03-09 | Gary Fujii | Composition and method for use for liposome encapsulated compounds for neutron capture tumor therapy |
| US5527528A (en) * | 1989-10-20 | 1996-06-18 | Sequus Pharmaceuticals, Inc. | Solid-tumor treatment method |
| EP0646019B9 (en) * | 1992-06-09 | 2002-12-18 | Neorx Corporation | Biotin-DOTA conjugates and their use in pretargeting methods |
| GB9420390D0 (en) * | 1994-10-10 | 1994-11-23 | Nycomed Salutar Inc | Liposomal agents |
| JP5064608B2 (ja) * | 1998-05-26 | 2012-10-31 | スローン−ケッタリング インスティトゥート フォー カンサー リサーチ | アルファ粒子放出構成物およびその使用方法 |
-
2000
- 2000-02-21 NO NO20000855A patent/NO312708B1/no not_active IP Right Cessation
-
2001
- 2001-02-21 NZ NZ520848A patent/NZ520848A/en not_active IP Right Cessation
- 2001-02-21 MX MXPA02008110A patent/MXPA02008110A/es active IP Right Grant
- 2001-02-21 WO PCT/NO2001/000065 patent/WO2001060417A2/en not_active Ceased
- 2001-02-21 AU AU2001237827A patent/AU2001237827B2/en not_active Ceased
- 2001-02-21 EP EP01910251A patent/EP1257299B9/en not_active Expired - Lifetime
- 2001-02-21 EA EA200200793A patent/EA005624B1/ru not_active IP Right Cessation
- 2001-02-21 DE DE60112251T patent/DE60112251T2/de not_active Expired - Lifetime
- 2001-02-21 PL PL358541A patent/PL201398B1/pl unknown
- 2001-02-21 DK DK01910251T patent/DK1257299T3/da active
- 2001-02-21 JP JP2001559512A patent/JP4933712B2/ja not_active Expired - Fee Related
- 2001-02-21 BR BR0108572-7A patent/BR0108572A/pt not_active IP Right Cessation
- 2001-02-21 US US09/790,260 patent/US6592843B2/en not_active Expired - Lifetime
- 2001-02-21 CA CA002400994A patent/CA2400994C/en not_active Expired - Fee Related
- 2001-02-21 UA UA2002086850A patent/UA73160C2/uk unknown
- 2001-02-21 ES ES01910251T patent/ES2247069T3/es not_active Expired - Lifetime
- 2001-02-21 CZ CZ20023164A patent/CZ299032B6/cs not_active IP Right Cessation
- 2001-02-21 AT AT01910251T patent/ATE300316T1/de active
- 2001-02-21 KR KR1020027010848A patent/KR100822566B1/ko not_active Expired - Fee Related
- 2001-02-21 AU AU3782701A patent/AU3782701A/xx active Pending
- 2001-02-21 CN CNB018053726A patent/CN100350981C/zh not_active Expired - Fee Related
-
2002
- 2002-08-14 ZA ZA200206500A patent/ZA200206500B/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |