NO314666B1 - DNA molekyl som koder for et rekombinant polypeptidenzym samt en vektor ogsammensetning inneholdende denne - Google Patents

DNA molekyl som koder for et rekombinant polypeptidenzym samt en vektor ogsammensetning inneholdende denne Download PDF

Info

Publication number
NO314666B1
NO314666B1 NO19943323A NO943323A NO314666B1 NO 314666 B1 NO314666 B1 NO 314666B1 NO 19943323 A NO19943323 A NO 19943323A NO 943323 A NO943323 A NO 943323A NO 314666 B1 NO314666 B1 NO 314666B1
Authority
NO
Norway
Prior art keywords
sialyltransferase
val
gly
sequence
leu
Prior art date
Application number
NO19943323A
Other languages
English (en)
Norwegian (no)
Other versions
NO943323L (no
NO943323D0 (no
Inventor
James C Paulson
Xiaohong Wen
Brian Livingston
William Gillespie
Sorge Kelm
Alma L Burlingame
Katalin Medzihradszky
Original Assignee
Cytel Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytel Corp filed Critical Cytel Corp
Publication of NO943323D0 publication Critical patent/NO943323D0/no
Publication of NO943323L publication Critical patent/NO943323L/no
Publication of NO314666B1 publication Critical patent/NO314666B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Ceramic Products (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO19943323A 1992-03-09 1994-09-08 DNA molekyl som koder for et rekombinant polypeptidenzym samt en vektor ogsammensetning inneholdende denne NO314666B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85035792A 1992-03-09 1992-03-09
US92536992A 1992-08-04 1992-08-04
PCT/US1993/002002 WO1993018157A1 (en) 1992-03-09 1993-03-09 Compositions and methods for the identification and synthesis of sialyltransferases

Publications (3)

Publication Number Publication Date
NO943323D0 NO943323D0 (no) 1994-09-08
NO943323L NO943323L (no) 1994-11-01
NO314666B1 true NO314666B1 (no) 2003-04-28

Family

ID=27126928

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19943323A NO314666B1 (no) 1992-03-09 1994-09-08 DNA molekyl som koder for et rekombinant polypeptidenzym samt en vektor ogsammensetning inneholdende denne

Country Status (17)

Country Link
EP (1) EP0632831B1 (de)
JP (1) JPH07505771A (de)
KR (1) KR100300467B1 (de)
AT (1) ATE228565T1 (de)
AU (1) AU668714B2 (de)
BG (1) BG62492B1 (de)
CA (1) CA2131703C (de)
CZ (1) CZ220494A3 (de)
DE (1) DE69332520T2 (de)
DK (1) DK0632831T3 (de)
ES (1) ES2191011T3 (de)
FI (1) FI119692B (de)
HU (1) HU219260B (de)
NO (1) NO314666B1 (de)
NZ (1) NZ251096A (de)
SK (1) SK108894A3 (de)
WO (1) WO1993018157A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5384249A (en) * 1991-12-17 1995-01-24 Kyowa Hakko Kogyo Co., Ltd. α2→3 sialyltransferase
CA2208291A1 (en) * 1994-12-22 1996-07-04 Boehringer Mannheim Gmbh Isolated polysialyl transferases, nucleic acid molecules coding therefor, methods of production and use
US5849904A (en) * 1994-12-22 1998-12-15 Boehringer Mannheim Gmbh Isolated nucleic acid molecules which hybridize to polysialyl transferases
AUPN658795A0 (en) * 1995-11-15 1995-12-07 Commonwealth Scientific And Industrial Research Organisation Method of producing alpha 2, 3 sialyltransferase
US6355255B1 (en) * 1998-12-07 2002-03-12 Regents Of The University Of Minnesota Streptococcal C5a peptidase vaccine
US6582691B1 (en) * 1998-02-12 2003-06-24 Aventis Research & Technologies Gmbh & Co. Expression vector for the production of dead proteins
US6194178B1 (en) 1998-09-03 2001-02-27 Synsorb Biotech Inc. Method for the production of sialylated oligosaccharides
US7173003B2 (en) 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
PL1615945T3 (pl) 2003-04-09 2012-03-30 Ratiopharm Gmbh Sposoby glikopegylacji i białka/peptydy wytwarzane tymi sposobami
US9005625B2 (en) 2003-07-25 2015-04-14 Novo Nordisk A/S Antibody toxin conjugates
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
US20080300173A1 (en) 2004-07-13 2008-12-04 Defrees Shawn Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1]
KR101324680B1 (ko) 2004-07-21 2013-11-06 세이가가쿠 고교 가부시키가이샤 아스파라긴 결합형 당쇄 수식을 받지않은 변이형 당단백질
WO2006050247A2 (en) 2004-10-29 2006-05-11 Neose Technologies, Inc. Remodeling and glycopegylation of fibroblast growth factor (fgf)
US9029331B2 (en) 2005-01-10 2015-05-12 Novo Nordisk A/S Glycopegylated granulocyte colony stimulating factor
WO2006121569A2 (en) 2005-04-08 2006-11-16 Neose Technologies, Inc. Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
WO2007056191A2 (en) 2005-11-03 2007-05-18 Neose Technologies, Inc. Nucleotide sugar purification using membranes
EP2049144B8 (de) 2006-07-21 2015-02-18 ratiopharm GmbH Glycosylierung von peptiden über o-verbundene glycosylierungssequenzen
EP2054521A4 (de) 2006-10-03 2012-12-19 Novo Nordisk As Verfahren zur reinigung von polypeptid-konjugate
HRP20130382T1 (hr) 2007-04-03 2013-05-31 Biogenerix Ag Postupci lijeäśenja pomoä†u glikopegiliranog g-csf
CA2690611C (en) 2007-06-12 2015-12-08 Novo Nordisk A/S Improved process for the production of nucleotide sugars
PL2257311T3 (pl) 2008-02-27 2014-09-30 Novo Nordisk As Koniugaty cząsteczek czynnika VIII
MX2011004755A (es) 2008-11-05 2011-10-10 Wyeth Llc Composicion inmunogenica multicomponente para la prevencion de enfermedad estreptococica beta-hemolitica (bhs).
AU2019211256A1 (en) 2018-01-23 2020-08-06 Praveen BHOOPATHI MDA-7/IL secretory variants and methods of use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5059535A (en) * 1989-04-12 1991-10-22 Chembiomed, Ltd. Process for the separation and purification of sialyl transferases
US5032519A (en) * 1989-10-24 1991-07-16 The Regents Of The Univ. Of California Method for producing secretable glycosyltransferases and other Golgi processing enzymes
DE4028800A1 (de) * 1990-09-11 1992-03-12 Behringwerke Ag Gentechnische sialylierung von glykoproteinen
SE9201544L (sv) * 1991-05-31 1992-12-01 Ciba Geigy Ag Saett att framstaella glykosyltransferaser
GB2256197B (en) * 1991-05-31 1995-11-22 Ciba Geigy Ag Yeast as host for expression of heterologous glycosyl transferase enzymes

Also Published As

Publication number Publication date
ATE228565T1 (de) 2002-12-15
ES2191011T3 (es) 2003-09-01
HU9402586D0 (en) 1994-11-28
NO943323L (no) 1994-11-01
HU219260B (en) 2001-03-28
DK0632831T3 (da) 2003-03-24
CZ220494A3 (en) 1995-03-15
AU668714B2 (en) 1996-05-16
AU3791993A (en) 1993-10-05
FI944136L (fi) 1994-11-08
FI944136A0 (fi) 1994-09-08
DE69332520D1 (de) 2003-01-09
JPH07505771A (ja) 1995-06-29
HUT69933A (en) 1995-09-28
KR100300467B1 (de) 2001-10-22
BG99100A (bg) 1995-05-31
FI119692B (fi) 2009-02-13
CA2131703A1 (en) 1993-09-16
WO1993018157A1 (en) 1993-09-16
CA2131703C (en) 2007-08-21
DE69332520T2 (de) 2003-09-11
EP0632831A1 (de) 1995-01-11
SK108894A3 (en) 1995-07-11
EP0632831B1 (de) 2002-11-27
BG62492B1 (bg) 1999-12-30
NZ251096A (en) 1996-03-26
NO943323D0 (no) 1994-09-08

Similar Documents

Publication Publication Date Title
NO314666B1 (no) DNA molekyl som koder for et rekombinant polypeptidenzym samt en vektor ogsammensetning inneholdende denne
US5962294A (en) Compositions and methods for the identification and synthesis of sialyltransferases
US5858751A (en) Compositions and methods for producing sialyltransferases
JP3193301B2 (ja) 生理活性タンパク質ｐ１６０
Hagen et al. Purification, cloning, and expression of a bovine UDP-GalNAc: polypeptide N-acetyl-galactosaminyltransferase.
NO340408B1 (no) Fremgangsmåte for å produsere humant alfa-galaktosidase A, og farmasøytisk preparat
JPH09501044A (ja) ＵＤＰ−ＧＡＬＮＡｃ：ポリペプチド、Ｎ−アセチルガラクトサミニルトランスフェラーゼをコードするクローン化されたＤＮＡ
EP1504023A2 (de) Rekombinante glycosyltransferase-fusionsproteine
NO329689B1 (no) Medisinske preparater til behandling av <alfa>-galaktosidase-A-defisiens
WO1998005768A1 (en) Improved nucleic acids encoding a chimeric glycosyltransferase
NO307305B1 (no) Fremgangsmåter og materialer for ekspresjon av en variant av humant plasminogen
US20230313158A1 (en) Soluble enpp1 proteins and uses thereof
EP0826054B1 (de) Glykosyltransferase expression in aspergillus
WO1997035959A1 (en) Production of galactosyltransferase
CA2003797A1 (en) Nucleotides encoding human b1, 4-galactosyltransferase and uses thereof
US20040191867A1 (en) DNA sequences coding for a mammalian glucuronyl C5-epimerase and a process for its production
Mucha et al. Two closely related forms of UDP-GlcNAc: α6-D-mannoside β1, 2-N-acetylglucosaminyltransferase II occur in the clawed frog Xenopus laevis
AU720984B2 (en) Improved nucleic acids encoding a chimeric glycosyltransferase
HK40090007A (zh) 可溶性enpp1或enpp3蛋白及其用途

Legal Events

Date Code Title Description
MK1K Patent expired