ATE228565T1 - Nukleinsäure, expressionsvektor und zusammensetzungen zur identifizierung und herstellung von rekombinanten sialyltransferasen - Google Patents

Nukleinsäure, expressionsvektor und zusammensetzungen zur identifizierung und herstellung von rekombinanten sialyltransferasen

Info

Publication number
ATE228565T1
ATE228565T1 AT93907244T AT93907244T ATE228565T1 AT E228565 T1 ATE228565 T1 AT E228565T1 AT 93907244 T AT93907244 T AT 93907244T AT 93907244 T AT93907244 T AT 93907244T AT E228565 T1 ATE228565 T1 AT E228565T1
Authority
AT
Austria
Prior art keywords
identifying
compositions
nucleic acid
expression vector
producing recombinant
Prior art date
Application number
AT93907244T
Other languages
English (en)
Inventor
James C Paulson
Xiaohong Wen
Brian Livingston
William Gillespie
Sorge Kelm
Alma L Burlingame
Katalin Medzihradszky
Original Assignee
Univ California
Cytel Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California, Cytel Corp filed Critical Univ California
Application granted granted Critical
Publication of ATE228565T1 publication Critical patent/ATE228565T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Ceramic Products (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT93907244T 1992-03-09 1993-03-09 Nukleinsäure, expressionsvektor und zusammensetzungen zur identifizierung und herstellung von rekombinanten sialyltransferasen ATE228565T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85035792A 1992-03-09 1992-03-09
US92536992A 1992-08-04 1992-08-04
PCT/US1993/002002 WO1993018157A1 (en) 1992-03-09 1993-03-09 Compositions and methods for the identification and synthesis of sialyltransferases

Publications (1)

Publication Number Publication Date
ATE228565T1 true ATE228565T1 (de) 2002-12-15

Family

ID=27126928

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93907244T ATE228565T1 (de) 1992-03-09 1993-03-09 Nukleinsäure, expressionsvektor und zusammensetzungen zur identifizierung und herstellung von rekombinanten sialyltransferasen

Country Status (17)

Country Link
EP (1) EP0632831B1 (de)
JP (1) JPH07505771A (de)
KR (1) KR100300467B1 (de)
AT (1) ATE228565T1 (de)
AU (1) AU668714B2 (de)
BG (1) BG62492B1 (de)
CA (1) CA2131703C (de)
CZ (1) CZ220494A3 (de)
DE (1) DE69332520T2 (de)
DK (1) DK0632831T3 (de)
ES (1) ES2191011T3 (de)
FI (1) FI119692B (de)
HU (1) HU219260B (de)
NO (1) NO314666B1 (de)
NZ (1) NZ251096A (de)
SK (1) SK108894A3 (de)
WO (1) WO1993018157A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5384249A (en) * 1991-12-17 1995-01-24 Kyowa Hakko Kogyo Co., Ltd. α2→3 sialyltransferase
WO1996020280A1 (en) * 1994-12-22 1996-07-04 Boehringer Mannheim Gmbh Isolated polysialyl transferases, nucleic acid molecules coding therefor, methods of production and use
US5849904A (en) * 1994-12-22 1998-12-15 Boehringer Mannheim Gmbh Isolated nucleic acid molecules which hybridize to polysialyl transferases
AUPN658795A0 (en) * 1995-11-15 1995-12-07 Commonwealth Scientific And Industrial Research Organisation Method of producing alpha 2, 3 sialyltransferase
US6355255B1 (en) 1998-12-07 2002-03-12 Regents Of The University Of Minnesota Streptococcal C5a peptidase vaccine
JP2002503474A (ja) * 1998-02-12 2002-02-05 アヴェンティス・リサーチ・ウント・テクノロジーズ・ゲーエムベーハー・ウント・コー・カーゲー Ｄｅａｄ蛋白質生産用発現ベクター
US6194178B1 (en) 1998-09-03 2001-02-27 Synsorb Biotech Inc. Method for the production of sialylated oligosaccharides
US7173003B2 (en) 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
SG155777A1 (en) 2003-04-09 2009-10-29 Neose Technologies Inc Glycopegylation methods and proteins/peptides produced by the methods
US9005625B2 (en) 2003-07-25 2015-04-14 Novo Nordisk A/S Antibody toxin conjugates
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
WO2006010143A2 (en) 2004-07-13 2006-01-26 Neose Technologies, Inc. Branched peg remodeling and glycosylation of glucagon-like peptide-1 [glp-1]
KR101324681B1 (ko) 2004-07-21 2013-11-04 세이가가쿠 고교 가부시키가이샤 아스파라긴 결합형 당쇄 수식을 받지않은 변이형 당단백질
PL2586456T3 (pl) 2004-10-29 2016-07-29 Ratiopharm Gmbh Remodeling i glikopegilacja czynnika wzrostu fibroblastów (FGF)
US9029331B2 (en) 2005-01-10 2015-05-12 Novo Nordisk A/S Glycopegylated granulocyte colony stimulating factor
EP1871795A4 (de) 2005-04-08 2010-03-31 Biogenerix Ag Zusammensetzungen und verfahren zur herstellung von glycosylierungsmutanten eines proteaseresistenten menschlichen wachstumshormons
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
WO2007056191A2 (en) 2005-11-03 2007-05-18 Neose Technologies, Inc. Nucleotide sugar purification using membranes
US20080248959A1 (en) 2006-07-21 2008-10-09 Neose Technologies, Inc. Glycosylation of peptides via o-linked glycosylation sequences
JP2010505874A (ja) 2006-10-03 2010-02-25 ノヴォ ノルディスク アー／エス ポリペプチドコンジュゲートの精製方法
BRPI0809670A8 (pt) 2007-04-03 2018-12-18 Biogenerix Ag métodos para aumentar a produção de célula tronco, para aumentar o número de granulócitos em um indivíduo, para prevenir, tratar e aliviar a mielossupressão que resulta de uma terapia contra o câncer, para tratar uma condição em um indivíduo, para tratar neutropenia e trombocitopenia em um mamífero, para expandir células tronco hematopoiéticas em cultura, para aumentar a hematopoiese em um indivíduo, para aumentar o número de célulars progenitoras hematopoiéticas em um indivíduo, e para fornecer enxerto estável da medula óssea, e, forma de dosagem oral.
MX2009013259A (es) 2007-06-12 2010-01-25 Novo Nordisk As Proceso mejorado para la produccion de azucares de nucleotidos.
ES2476690T3 (es) 2008-02-27 2014-07-15 Novo Nordisk A/S Moléculas conjugadas del Factor VIII
NZ614064A (en) 2008-11-05 2015-04-24 Wyeth Llc Multicomponent immunogenic composition for the prevention of beta-hemolytic streptococcal (bhs) disease
US12325863B2 (en) 2018-01-23 2025-06-10 Virginia Commonwealth University MDA-7/IL-24 secretory variants and methods of use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5059535A (en) * 1989-04-12 1991-10-22 Chembiomed, Ltd. Process for the separation and purification of sialyl transferases
US5032519A (en) * 1989-10-24 1991-07-16 The Regents Of The Univ. Of California Method for producing secretable glycosyltransferases and other Golgi processing enzymes
DE4028800A1 (de) * 1990-09-11 1992-03-12 Behringwerke Ag Gentechnische sialylierung von glykoproteinen
GB2256197B (en) * 1991-05-31 1995-11-22 Ciba Geigy Ag Yeast as host for expression of heterologous glycosyl transferase enzymes
SE9201544L (sv) * 1991-05-31 1992-12-01 Ciba Geigy Ag Saett att framstaella glykosyltransferaser

Also Published As

Publication number Publication date
NO943323D0 (no) 1994-09-08
DK0632831T3 (da) 2003-03-24
JPH07505771A (ja) 1995-06-29
SK108894A3 (en) 1995-07-11
EP0632831A1 (de) 1995-01-11
CA2131703A1 (en) 1993-09-16
KR100300467B1 (de) 2001-10-22
FI119692B (fi) 2009-02-13
WO1993018157A1 (en) 1993-09-16
EP0632831B1 (de) 2002-11-27
BG62492B1 (bg) 1999-12-30
NZ251096A (en) 1996-03-26
FI944136A0 (fi) 1994-09-08
AU3791993A (en) 1993-10-05
DE69332520D1 (de) 2003-01-09
FI944136L (fi) 1994-11-08
HU9402586D0 (en) 1994-11-28
NO314666B1 (no) 2003-04-28
CZ220494A3 (en) 1995-03-15
HU219260B (en) 2001-03-28
ES2191011T3 (es) 2003-09-01
HUT69933A (en) 1995-09-28
NO943323L (no) 1994-11-01
CA2131703C (en) 2007-08-21
DE69332520T2 (de) 2003-09-11
BG99100A (bg) 1995-05-31
AU668714B2 (en) 1996-05-16

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