NO319313B1 - Anvendelse av en synergistisk kombinasjon av en opioidantagonist og en NMDA reseptorkompleksmodulator for behandling av alkoholavhengighet - Google Patents

Anvendelse av en synergistisk kombinasjon av en opioidantagonist og en NMDA reseptorkompleksmodulator for behandling av alkoholavhengighet Download PDF

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Publication number
NO319313B1
NO319313B1 NO20004788A NO20004788A NO319313B1 NO 319313 B1 NO319313 B1 NO 319313B1 NO 20004788 A NO20004788 A NO 20004788A NO 20004788 A NO20004788 A NO 20004788A NO 319313 B1 NO319313 B1 NO 319313B1
Authority
NO
Norway
Prior art keywords
nmda receptor
opioid antagonist
receptor complex
treatment
complex modulator
Prior art date
Application number
NO20004788A
Other languages
English (en)
Norwegian (no)
Other versions
NO20004788D0 (no
NO20004788L (no
Inventor
Philippe Durbin
Yves Bonhomme
Martine Daoust
Original Assignee
Lipha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lipha filed Critical Lipha
Publication of NO20004788D0 publication Critical patent/NO20004788D0/no
Publication of NO20004788L publication Critical patent/NO20004788L/no
Publication of NO319313B1 publication Critical patent/NO319313B1/no

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20004788A 1998-03-26 2000-09-25 Anvendelse av en synergistisk kombinasjon av en opioidantagonist og en NMDA reseptorkompleksmodulator for behandling av alkoholavhengighet NO319313B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98400723A EP0945133A1 (en) 1998-03-26 1998-03-26 Combination for the treatment of alcohol and drug dependence containing an opioid antagonist and a NMDA receptor complex modulator
PCT/EP1999/002337 WO1999048500A1 (en) 1998-03-26 1999-03-26 Combination for the treatment of alcohol and drug dependence containing an opioid antagonist and a nmda receptor complex modulator

Publications (3)

Publication Number Publication Date
NO20004788D0 NO20004788D0 (no) 2000-09-25
NO20004788L NO20004788L (no) 2000-11-24
NO319313B1 true NO319313B1 (no) 2005-07-11

Family

ID=8235311

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20004788A NO319313B1 (no) 1998-03-26 2000-09-25 Anvendelse av en synergistisk kombinasjon av en opioidantagonist og en NMDA reseptorkompleksmodulator for behandling av alkoholavhengighet

Country Status (17)

Country Link
US (1) US6512009B1 (pl)
EP (2) EP0945133A1 (pl)
KR (1) KR20010034678A (pl)
AT (1) ATE230993T1 (pl)
AU (1) AU758569B2 (pl)
BR (1) BR9909138A (pl)
CA (1) CA2325739C (pl)
CZ (1) CZ296367B6 (pl)
DE (1) DE69904922T2 (pl)
DK (1) DK1063995T3 (pl)
ES (1) ES2190205T3 (pl)
HU (1) HU226555B1 (pl)
NO (1) NO319313B1 (pl)
PL (1) PL193241B1 (pl)
RU (1) RU2226107C2 (pl)
SK (1) SK284623B6 (pl)
WO (1) WO1999048500A1 (pl)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6913761B1 (en) * 1998-07-20 2005-07-05 Peptech Limited Bioimplant formulation
US8052982B2 (en) 1998-07-20 2011-11-08 Peptech Animal Health Pty Limited Bioimplant formulation comprising lecithin and stearin
WO2001052851A1 (en) * 2000-01-22 2001-07-26 Albert Shulman Methods for the treatment of substance abuse
EP1262196A3 (en) * 2001-05-23 2002-12-18 Pfizer Products Inc. Combination of a monoamine reuptake inhibitor and an opioid antagonist for use in alcoholism and alcohol dependence
DE10129265A1 (de) * 2001-06-18 2003-01-02 Hf Arzneimittelforsch Gmbh Wirkstoff-Kombination zur medikamentösen Sucht- oder Rauschmitteltherapie
ES2187288B1 (es) * 2001-09-24 2004-09-16 Garbil Pharma Investigacion Chile Ltda Aminas como agentes anti-alcoholismo.
PT2561860T (pt) 2002-05-31 2018-05-08 Titan Pharmaceuticals Inc Dispositivo polimérico implantável para a libertação prolongada de buprenorfina
ATE482695T1 (de) 2002-12-13 2010-10-15 Durect Corp Orale darreichungsform mit flüssigen hochviskosen trägersystemen
US20040224020A1 (en) * 2002-12-18 2004-11-11 Schoenhard Grant L. Oral dosage forms with therapeutically active agents in controlled release cores and immediate release gelatin capsule coats
CA2520613C (en) 2003-03-31 2012-12-04 Titan Pharmaceuticals, Inc. Implantable polymeric device for sustained release of dopamine agonist
WO2004110400A2 (en) * 2003-05-30 2004-12-23 Titan Pharmaceuticals, Inc. Implantable polymeric device for sustained release of nalmefene
US20070099947A1 (en) * 2005-11-03 2007-05-03 Alkermes, Inc. Methods and compositions for the treatment of brain reward system disorders by combination therapy
JP2010513569A (ja) * 2006-12-19 2010-04-30 ユニバーシティ オブ バージニア パテント ファウンデーション アルコール摂取に対するトピラメートおよびオンダンセトロンの併用効果
WO2009075782A1 (en) * 2007-12-06 2009-06-18 Durect Corporation Methods useful for the treatment of pain, arthritic conditions, or inflammation associated with a chronic condition
ES2430940T3 (es) 2008-02-28 2013-11-22 University Of Virginia Patent Foundation Gen del transportador de serotonina y tratamiento del alcoholismo
US20100260844A1 (en) 2008-11-03 2010-10-14 Scicinski Jan J Oral pharmaceutical dosage forms
HUE035574T2 (en) 2010-07-02 2018-05-28 Univ Virginia Patent Foundation Molecular genetic approach to treatment and diagnosis of alcohol and drug dependence
US20130096173A1 (en) 2011-09-09 2013-04-18 Bankole A. Johnson Molecular genetic approach to treatment and diagnosis of alcohol and drug dependence
RU2476209C1 (ru) * 2012-02-29 2013-02-27 Станислав Анатольевич Кедик Имплантируемое лекарственное средство на основе налтрексона для лечения пациентов, зависимых от алкоголя или опиатов
CA2905131A1 (en) 2013-03-15 2014-09-18 Durect Corporation Compositions with a rheological modifier to reduce dissolution variability
GB201308440D0 (en) * 2013-05-10 2013-06-19 Dalgleish Angus Therapeutic
US12274794B2 (en) 2016-07-06 2025-04-15 Orient Pharma Co., Ltd. Oral dosage form with drug composition, barrier layer and drug layer
US20240350433A1 (en) * 2021-08-17 2024-10-24 Yale University Treatment compositions and methods

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4882335A (en) * 1988-06-13 1989-11-21 Alko Limited Method for treating alcohol-drinking response
JPH11505547A (ja) * 1996-03-13 1999-05-21 エール ユニバーシティ ナルトレキソン及び関連化合物を用いる禁煙処置

Also Published As

Publication number Publication date
EP1063995A1 (en) 2001-01-03
DE69904922T2 (de) 2004-01-08
KR20010034678A (ko) 2001-04-25
ATE230993T1 (de) 2003-02-15
WO1999048500A1 (en) 1999-09-30
HUP0101546A3 (en) 2002-10-28
CA2325739C (en) 2007-05-15
AU758569B2 (en) 2003-03-27
SK284623B6 (sk) 2005-08-04
EP0945133A1 (en) 1999-09-29
PL343069A1 (en) 2001-07-30
RU2226107C2 (ru) 2004-03-27
PL193241B1 (pl) 2007-01-31
SK14282000A3 (sk) 2001-05-10
CA2325739A1 (en) 1999-09-30
BR9909138A (pt) 2000-12-05
AU3522699A (en) 1999-10-18
US6512009B1 (en) 2003-01-28
NO20004788D0 (no) 2000-09-25
HK1032542A1 (en) 2001-07-27
DK1063995T3 (da) 2003-03-10
HUP0101546A2 (hu) 2001-09-28
HU226555B1 (en) 2009-03-30
NO20004788L (no) 2000-11-24
CZ20003525A3 (cs) 2001-04-11
EP1063995B1 (en) 2003-01-15
DE69904922D1 (de) 2003-02-20
ES2190205T3 (es) 2003-07-16
CZ296367B6 (cs) 2006-02-15

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