NO319633B1 - Anvendelse av cystein-derivater for fremstilling av et medikament for forebygging av overvekt, forbindelsen 7-(2-amino-1-okso-3-tiopropyl)-8-(cykloheksylmetyl)-2-(2-metylfenyl)-5,6,7,8-tetrahydroimidazo[1.2a]pyrazin, anvendelse derav og farmasoytisk preparat pa grunnlag derav - Google Patents

Anvendelse av cystein-derivater for fremstilling av et medikament for forebygging av overvekt, forbindelsen 7-(2-amino-1-okso-3-tiopropyl)-8-(cykloheksylmetyl)-2-(2-metylfenyl)-5,6,7,8-tetrahydroimidazo[1.2a]pyrazin, anvendelse derav og farmasoytisk preparat pa grunnlag derav Download PDF

Info

Publication number: NO319633B1
Authority: NO; Norway
Prior art keywords: oxo; amino; thiopropyl; tetrahydroimidazo; pyrazine
Prior art date: 1998-07-08

Application number

NO20010029A

Other languages

English (en)

Norwegian (no)

Other versions

NO20010029D0 (no

NO20010029L (no

Inventor

Thomas D Gordon

Gregoire Prevost

Marie-Odile Lonchampt

Original Assignee

Sod Conseils Rech Applic

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-07-08

Filing date

2001-01-03

Publication date

2005-09-05

2001-01-03 Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic

2001-01-03 Publication of NO20010029D0 publication Critical patent/NO20010029D0/no

2001-01-08 Publication of NO20010029L publication Critical patent/NO20010029L/no

2005-09-05 Publication of NO319633B1 publication Critical patent/NO319633B1/no

Links

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NO20010029A 1998-07-08 2001-01-03 Anvendelse av cystein-derivater for fremstilling av et medikament for forebygging av overvekt, forbindelsen 7-(2-amino-1-okso-3-tiopropyl)-8-(cykloheksylmetyl)-2-(2-metylfenyl)-5,6,7,8-tetrahydroimidazo[1.2a]pyrazin, anvendelse derav og farmasoytisk preparat pa grunnlag derav NO319633B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9808731A FR2780974B1 (fr)	1998-07-08	1998-07-08	Utilisation de derives d'imidazopyrazines pour preparer un medicament destine a traiter les pathologies qui resultent de la formation de la proteine g heterotrimetrique
PCT/FR1999/001609 WO2000002881A2 (fr)	1998-07-08	1999-07-05	Utilisation de derives de la cysteine pour preparer un medicament destine a traiter les pathologies qui resultent de la formation de la proteine g heterotrimerique

Publications (3)

Publication Number	Publication Date
NO20010029D0 NO20010029D0 (no)	2001-01-03
NO20010029L NO20010029L (no)	2001-01-08
NO319633B1 true NO319633B1 (no)	2005-09-05

Family

ID=9528405

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20010029A NO319633B1 (no)	1998-07-08	2001-01-03	Anvendelse av cystein-derivater for fremstilling av et medikament for forebygging av overvekt, forbindelsen 7-(2-amino-1-okso-3-tiopropyl)-8-(cykloheksylmetyl)-2-(2-metylfenyl)-5,6,7,8-tetrahydroimidazo[1.2a]pyrazin, anvendelse derav og farmasoytisk preparat pa grunnlag derav

Country Status (17)

Country	Link
US (3)	US6544995B1 (de)
EP (1)	EP1100801B1 (de)
JP (1)	JP2002520327A (de)
AR (1)	AR019908A1 (de)
AT (1)	ATE459625T1 (de)
AU (1)	AU756268B2 (de)
CA (1)	CA2336846C (de)
DE (1)	DE69942095D1 (de)
ES (1)	ES2341404T3 (de)
FR (1)	FR2780974B1 (de)
MY (1)	MY122419A (de)
NO (1)	NO319633B1 (de)
NZ (1)	NZ509789A (de)
RU (1)	RU2268889C2 (de)
TW (1)	TW561156B (de)
WO (1)	WO2000002881A2 (de)
ZA (1)	ZA200101061B (de)

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* Cited by examiner, † Cited by third party
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FR2780974B1 (fr) *	1998-07-08	2001-09-28	Sod Conseils Rech Applic	Utilisation de derives d'imidazopyrazines pour preparer un medicament destine a traiter les pathologies qui resultent de la formation de la proteine g heterotrimetrique
ES2215420T3 (es) *	1998-12-31	2004-10-01	Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S.	Inhibidores de la prenil-transferasa.
US7084135B1 (en)	1998-12-31	2006-08-01	Societe De Conseils De Recherches Et D'applications Scientifiques, Sas	Prenyl transferase inhibitors
DE10112926B4 (de) *	2001-03-13	2005-11-10	Schebo Biotech Ag	Verwendung von Aminooxyacetat zur Tumorbehandlung
DE10112925A1 (de) *	2001-03-13	2002-10-02	Erich Eigenbrodt	Verwendung von Zuckerphosphaten, Zuckerphosphatanalogen, Aminosäuren, Aminosäureanalogen zur Modulation von Transaminasen und/oder der Assoziation p36/Malat Dehydrogenase
UA74912C2 (en)	2001-07-06	2006-02-15	Merck & Co Inc	Beta-aminotetrahydroimidazo-(1,2-a)-pyrazines and tetratriazolo-(4,3-a)-pyrazines as inhibitors of dipeptylpeptidase for the treatment or prevention of diabetes
CA2508947A1 (en) *	2002-12-20	2004-07-15	Merck & Co., Inc.	3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
FR2879460B1 (fr) *	2004-12-17	2007-02-23	Sod Conseils Rech Applic	Associations anti-douleur comprenant un derive de dihydroimidazopyrazine
FR2921658A1 (fr) *	2007-09-27	2009-04-03	Sod Conseils Rech Applic	Derives des pyrazolo-pyrazines comme inhibiteurs de proteines g
CN101824036A (zh) *	2009-03-05	2010-09-08	上海恒瑞医药有限公司	四氢咪唑并[1，5-a]吡嗪衍生物的盐,其制备方法及其在医药上的应用
AR077463A1 (es)	2009-07-09	2011-08-31	Irm Llc	Derivados de imidazo[1, 2 - a]pirazina y su uso en medicamentos para el tratamiento de enfermedades parasitarias
CN110691597A (zh)	2017-04-24	2020-01-14	诺华股份有限公司	2-氨基-1-(2-(4-氟苯基)-3-(4-氟苯基氨基)-8,8-二甲基-5,6-二氢咪唑并[1,2-a]吡嗪-7(8H)-基)乙酮及其组合的治疗方案
CN112480122B (zh) *	2020-11-24	2022-03-22	中山大学	一种四氢咪唑[1,2-a]吡嗪类化合物、组合物及其制备方法与应用

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UA39849C2 (uk) *	1991-03-26	2001-07-16	Ф.Хоффманн-Ля Рош Аг	ПОХІДНІ N-АЦИЛ-<font face="Symbol">a</font>-АМІНОКИСЛОТИ АБО ЇХ ФІЗІОЛОГІЧНО ПРИЙНЯТНІ СОЛІ, ПРОСТІ АБО СКЛАДНІ ЕФІРИ, АМІДИ АБО ЇХ ГІДРАТИ ЯК ФАРМАЦЕВТИЧНО АКТИВНІ РЕЧОВИНИ
EP0537007B1 (de) *	1991-10-11	1995-08-09	E.R. SQUIBB & SONS, INC.	Verwendung von Farnesyl-Protein Transferaseinhibitoren zur Herstellung eines Arzneimittels zur Blockierung von durch Ras-Oncogenen hervorgerufenen neoplastischen Transformationen von Zellen
GB9226065D0 (en) *	1992-12-14	1993-02-10	Ici Plc	Peptides
US5705686A (en) *	1993-05-18	1998-01-06	University Of Pittsburgh	Inhibition of farnesyl transferase
WO1995000497A1 (en) *	1993-06-18	1995-01-05	Merck & Co., Inc.	Inhibitors of farnesyl-protein transferase
CA2188950C (en) *	1994-04-26	2001-07-03	James R. Broach	Functional expression of mammalian adenylyl cyclase in yeast
CA2159850A1 (en) *	1994-11-03	1996-05-04	Yadagiri Pendri	Phosphonosulfonate squalene synthetase inhibitor salts and method
AU4915796A (en) *	1995-01-12	1996-07-31	University Of Pittsburgh	Inhibitors of prenyl transferases
FR2736638B1 (fr) *	1995-07-12	1997-08-22	Rhone Poulenc Rorer Sa	Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
US6673927B2 (en) *	1996-02-16	2004-01-06	Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S.	Farnesyl transferase inhibitors
US20020034725A1 (en) *	1996-04-15	2002-03-21	W. Gillies Mckenna	Sensitization of cells to radiation and and chemotherapy
US5935812A (en) *	1996-09-18	1999-08-10	Incyte Pharmaceuticals, Inc.	Human GTP binding protein gamma-3
RU2201931C2 (ru) *	1996-11-20	2003-04-10	Биомежер Инкорпорэйтед	Ингибиторы фарнезилтрансферазы и способы ингибирования фарнезилтрансферазы
FR2780974B1 (fr) *	1998-07-08	2001-09-28	Sod Conseils Rech Applic	Utilisation de derives d'imidazopyrazines pour preparer un medicament destine a traiter les pathologies qui resultent de la formation de la proteine g heterotrimetrique

1998
- 1998-07-08 FR FR9808731A patent/FR2780974B1/fr not_active Expired - Fee Related
1999
- 1999-07-05 AU AU46222/99A patent/AU756268B2/en not_active Ceased
- 1999-07-05 RU RU2001103647/15A patent/RU2268889C2/ru not_active IP Right Cessation
- 1999-07-05 ES ES99929394T patent/ES2341404T3/es not_active Expired - Lifetime
- 1999-07-05 WO PCT/FR1999/001609 patent/WO2000002881A2/fr not_active Ceased
- 1999-07-05 JP JP2000559111A patent/JP2002520327A/ja active Pending
- 1999-07-05 US US09/743,208 patent/US6544995B1/en not_active Expired - Fee Related
- 1999-07-05 CA CA2336846A patent/CA2336846C/en not_active Expired - Fee Related
- 1999-07-05 DE DE69942095T patent/DE69942095D1/de not_active Expired - Lifetime
- 1999-07-05 EP EP99929394A patent/EP1100801B1/de not_active Expired - Lifetime
- 1999-07-05 AT AT99929394T patent/ATE459625T1/de not_active IP Right Cessation
- 1999-07-05 NZ NZ509789A patent/NZ509789A/en not_active IP Right Cessation
- 1999-07-07 MY MYPI99002848A patent/MY122419A/en unknown
- 1999-07-08 AR ARP990103337A patent/AR019908A1/es not_active Application Discontinuation
- 1999-07-17 TW TW088111517A patent/TW561156B/zh not_active IP Right Cessation
2001
- 2001-01-03 NO NO20010029A patent/NO319633B1/no not_active IP Right Cessation
- 2001-02-07 ZA ZA200101061A patent/ZA200101061B/xx unknown
2003
- 2003-02-03 US US10/356,862 patent/US7034025B2/en not_active Expired - Fee Related
2005
- 2005-09-09 US US11/222,601 patent/US20060035899A1/en not_active Abandoned

Also Published As

Publication number	Publication date
NO20010029D0 (no)	2001-01-03
ES2341404T3 (es)	2010-06-18
NZ509789A (en)	2004-01-30
US20030162786A1 (en)	2003-08-28
AR019908A1 (es)	2002-03-20
FR2780974B1 (fr)	2001-09-28
AU4622299A (en)	2000-02-01
WO2000002881A3 (fr)	2000-03-16
FR2780974A1 (fr)	2000-01-14
US20060035899A1 (en)	2006-02-16
US7034025B2 (en)	2006-04-25
DE69942095D1 (de)	2010-04-15
MY122419A (en)	2006-04-29
ATE459625T1 (de)	2010-03-15
US6544995B1 (en)	2003-04-08
EP1100801A2 (de)	2001-05-23
ZA200101061B (en)	2002-10-02
JP2002520327A (ja)	2002-07-09
AU756268B2 (en)	2003-01-09
EP1100801B1 (de)	2010-03-03
RU2268889C2 (ru)	2006-01-27
CA2336846A1 (en)	2000-01-20
NO20010029L (no)	2001-01-08
TW561156B (en)	2003-11-11
CA2336846C (en)	2010-03-16
WO2000002881A2 (fr)	2000-01-20

Legal Events

Date	Code	Title	Description
2012-02-20	MM1K	Lapsed by not paying the annual fees

Publication	Publication Date	Title
NO319633B1 (no)	2005-09-05	Anvendelse av cystein-derivater for fremstilling av et medikament for forebygging av overvekt, forbindelsen 7-(2-amino-1-okso-3-tiopropyl)-8-(cykloheksylmetyl)-2-(2-metylfenyl)-5,6,7,8-tetrahydroimidazo[1.2a]pyrazin, anvendelse derav og farmasoytisk preparat pa grunnlag derav
EA002819B1 (ru)	2002-10-31	Циклическое пептидное соединение и его применение, бициклопептидное соединение, пептидное соединение и его применение, фармацевтическая композиция
US10316056B2 (en)	2019-06-11	Chemical compounds and use thereof for improving muscular quality
US6489331B1 (en)	2002-12-03	Remedies for diabetes
CA2395414A1 (en)	2001-07-05	Condensed purine derivative
JP2001106691A (ja)	2001-04-17	インドロカルバゾールおよびその使用
JPH06135992A (ja)	1994-05-17	ミクロビスポラから単離された新規エンドセリンレセプター拮抗剤
BR112020013237A2 (pt)	2020-12-01	derivados de amino-metilpiperidina como iniciador quinase
EP0699204A1 (de)	1996-03-06	Anwendung von indolocarbazol-derivaten zur behandlung von prostataerkrankungen
NZ256589A (en)	1996-05-28	Condensed azepine analogues and medicaments (where a is c, o or s and b is o or s)
US6136798A (en)	2000-10-24	Compounds inhibiting the association of the PDGF receptor and phosphatidylinositol 3-kinase and their use
AU2007358076A1 (en)	2009-02-26	Indolopyridines as inhibitors of the kinesin spindle protein (Eg5 )
Ohtsuka et al.	1993	Tetronothiodin, a novel cholecystokinin type-B receptor antagonist produced by Streptomyces sp. NR0489 II. Isolation, characterization and biological activities
NO172935B (no)	1993-06-21	Analogifremgangsmaate for fremstilling av terapeutisk aktive amid-derivater
NO813700L (no)	1982-05-04	2,6-d-dimetyltyrosin1-d-aminosyre2-epsilon-aminokapronsyre- og gamma-aminosmoersyrederivater av metioninenkefalin, og fremgangsmaate for deres fremstilling
US5462926A (en)	1995-10-31	Neuromedin B receptor antagonists which demonstrate selectivity
US20110263672A1 (en)	2011-10-27	Metabolites of Wortmannin Analogs and Methods of Using the Same
JP2001527079A (ja)	2001-12-25	Ｋ−２５２ａの３’−エピマー誘導体
CA2612482A1 (en)	2007-01-25	Biologically active compounds obtainable from sorangium cellulosum
WO2009071957A2 (en)	2009-06-11	Novel peptides and amino acid derivatives, pharmaceutical compositions containing same and the use of these compounds
NO761942L (de)	1976-12-10
FI109129B (fi)	2002-05-31	Menetelmä 2-substituoitujen adenosiinien valmistamiseksi, joilla on A-2-reseptoriaffiniteetti
JP2003503412A (ja)	2003-01-28	海洋放線菌に由来する新規のインドロカルバゾールアルカロイド
JPWO2003104265A1 (ja)	2005-10-06	グリシントランスポーター阻害活性を有する化合物
FR2796381A1 (fr)	2001-01-19	Derives bicycliques de thioazepine ou de caprolactame, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant