NO320839B1 - Isolert polypeptid, fremgangsmate for dets fremstilling, isolert nukleinsyremolekyl, isolert antistoff, antisensemolekyl, preparat, anvendelse av henholdsvis et polypeptid og et nukleinsyremolekyl, vertscelle samt vektor. - Google Patents

Isolert polypeptid, fremgangsmate for dets fremstilling, isolert nukleinsyremolekyl, isolert antistoff, antisensemolekyl, preparat, anvendelse av henholdsvis et polypeptid og et nukleinsyremolekyl, vertscelle samt vektor. Download PDF

Info

Publication number: NO320839B1
Authority: NO; Norway
Prior art keywords: seq; polypeptide; isolated; nucleic acid; amino acid
Prior art date: 1995-03-02

Application number

NO19974035A

Other languages

English (en)

Norwegian (no)

Other versions

NO974035D0 (no

NO974035L (no

Inventor

Nicholas Kim Hayward

Gunther Weber

Sean Grimmond

Magnus Nordenskjold

Catharina Larsson

Original Assignee

Amrad Operations Pty Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-03-02

Filing date

1997-09-02

Publication date

2006-01-30

1995-03-02 Priority claimed from AUPN1457A external-priority patent/AUPN145795A0/en

1995-11-20 Priority claimed from AUPN6647A external-priority patent/AUPN664795A0/en

1995-12-22 Priority claimed from AUPN7274A external-priority patent/AUPN727495A0/en

1997-09-02 Application filed by Amrad Operations Pty Ltd filed Critical Amrad Operations Pty Ltd

1997-09-02 Publication of NO974035D0 publication Critical patent/NO974035D0/no

1997-11-03 Publication of NO974035L publication Critical patent/NO974035L/no

2006-01-30 Publication of NO320839B1 publication Critical patent/NO320839B1/no

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210000001087 myotubule Anatomy 0.000 description 1
210000005036 nerve Anatomy 0.000 description 1
210000000653 nervous system Anatomy 0.000 description 1
210000000933 neural crest Anatomy 0.000 description 1
210000000276 neural tube Anatomy 0.000 description 1
238000003522 neurite outgrowth assay Methods 0.000 description 1
230000006576 neuronal survival Effects 0.000 description 1
239000003900 neurotrophic factor Substances 0.000 description 1
230000003472 neutralizing effect Effects 0.000 description 1
210000000584 nodose ganglion Anatomy 0.000 description 1
229920002113 octoxynol Polymers 0.000 description 1
230000002018 overexpression Effects 0.000 description 1
230000007030 peptide scission Effects 0.000 description 1
210000002856 peripheral neuron Anatomy 0.000 description 1
230000035699 permeability Effects 0.000 description 1
239000000825 pharmaceutical preparation Substances 0.000 description 1
208000028591 pheochromocytoma Diseases 0.000 description 1
239000008363 phosphate buffer Substances 0.000 description 1
230000028742 placenta development Effects 0.000 description 1
239000013612 plasmid Substances 0.000 description 1
239000002797 plasminogen activator inhibitor Substances 0.000 description 1
108010055896 polyornithine Proteins 0.000 description 1
239000001267 polyvinylpyrrolidone Substances 0.000 description 1
235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
244000144977 poultry Species 0.000 description 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
230000037452 priming Effects 0.000 description 1
230000002062 proliferating effect Effects 0.000 description 1
238000011321 prophylaxis Methods 0.000 description 1
238000010188 recombinant method Methods 0.000 description 1
230000019705 regulation of vascular permeability Effects 0.000 description 1
230000002629 repopulating effect Effects 0.000 description 1
230000007441 retrograde transport Effects 0.000 description 1
206010039073 rheumatoid arthritis Diseases 0.000 description 1
108091092562 ribozyme Proteins 0.000 description 1
235000019515 salmon Nutrition 0.000 description 1
229940016590 sarkosyl Drugs 0.000 description 1
210000002027 skeletal muscle Anatomy 0.000 description 1
210000002363 skeletal muscle cell Anatomy 0.000 description 1
NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
210000003594 spinal ganglia Anatomy 0.000 description 1
125000000446 sulfanediyl group Chemical group *S* 0.000 description 1
229940124597 therapeutic agent Drugs 0.000 description 1
238000004448 titration Methods 0.000 description 1
150000004992 toluidines Chemical class 0.000 description 1
238000011282 treatment Methods 0.000 description 1
239000001226 triphosphate Substances 0.000 description 1
235000011178 triphosphate Nutrition 0.000 description 1
UNXRWKVEANCORM-UHFFFAOYSA-N triphosphoric acid Chemical compound OP(O)(=O)OP(O)(=O)OP(O)(O)=O UNXRWKVEANCORM-UHFFFAOYSA-N 0.000 description 1
HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
229940038773 trisodium citrate Drugs 0.000 description 1
239000012588 trypsin Substances 0.000 description 1
238000011144 upstream manufacturing Methods 0.000 description 1
210000005166 vasculature Anatomy 0.000 description 1
230000002227 vasoactive effect Effects 0.000 description 1
230000002861 ventricular Effects 0.000 description 1
230000035899 viability Effects 0.000 description 1
238000005406 washing Methods 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
239000011592 zinc chloride Substances 0.000 description 1
235000005074 zinc chloride Nutrition 0.000 description 1
JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical compound [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Pharmacology & Pharmacy (AREA)
Molecular Biology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biotechnology (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Physics & Mathematics (AREA)
Epidemiology (AREA)
Cardiology (AREA)
Neurology (AREA)
Vascular Medicine (AREA)
Plant Pathology (AREA)
Microbiology (AREA)
Heart & Thoracic Surgery (AREA)
Neurosurgery (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

NO19974035A 1995-03-02 1997-09-02 Isolert polypeptid, fremgangsmate for dets fremstilling, isolert nukleinsyremolekyl, isolert antistoff, antisensemolekyl, preparat, anvendelse av henholdsvis et polypeptid og et nukleinsyremolekyl, vertscelle samt vektor. NO320839B1 (no)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
AUPN1457A AUPN145795A0 (en)	1995-03-02	1995-03-02	A novel growth factor and a genetic sequence encoding same
AUPN6647A AUPN664795A0 (en)	1995-11-20	1995-11-20	A novel growth factor and a genetic sequence encoding same
AUPN7274A AUPN727495A0 (en)	1995-12-22	1995-12-22	A novel growth factor and a genetic sequence encoding same-II
PCT/AU1996/000094 WO1996027007A1 (fr)	1995-03-02	1996-02-22	Nouveau facteur de croissance et sequence genetique codant ce facteur

Publications (3)

Publication Number	Publication Date
NO974035D0 NO974035D0 (no)	1997-09-02
NO974035L NO974035L (no)	1997-11-03
NO320839B1 true NO320839B1 (no)	2006-01-30

Family

ID=27157841

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19974035A NO320839B1 (no)	1995-03-02	1997-09-02	Isolert polypeptid, fremgangsmate for dets fremstilling, isolert nukleinsyremolekyl, isolert antistoff, antisensemolekyl, preparat, anvendelse av henholdsvis et polypeptid og et nukleinsyremolekyl, vertscelle samt vektor.

Country Status (15)

Country	Link
US (1)	US20070135344A1 (fr)
EP (1)	EP0815221B1 (fr)
JP (2)	JPH11500139A (fr)
KR (1)	KR100414615B1 (fr)
CN (1)	CN1194090C (fr)
AT (1)	ATE252600T1 (fr)
BR (1)	BR9607628A (fr)
CA (1)	CA2214439C (fr)
DE (1)	DE69630442T2 (fr)
ES (1)	ES2206558T3 (fr)
FI (1)	FI120153B (fr)
HU (1)	HU223438B1 (fr)
NO (1)	NO320839B1 (fr)
NZ (2)	NZ301611A (fr)
WO (1)	WO1996027007A1 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5928939A (en)	1995-03-01	1999-07-27	Ludwig Institute For Cancer Research	Vascular endothelial growth factor-b and dna coding therefor
WO1996039421A1 (fr) *	1995-06-06	1996-12-12	Human Genome Sciences, Inc.	Facteur de croissance 3 de l'endothelium vasculaire humain
ES2202469T5 (es)	1995-09-08	2011-06-06	Genentech, Inc.	Proteína relacionada con el vegf.
DE69638142D1 (de)	1995-09-29	2010-04-15	Univ Siena	Regulierte Gene und ihre Verwendungen
AU1116297A (en)	1995-11-08	1997-05-29	Immunex Corporation	Flk-1 binding protein
US6994989B1 (en)	1995-11-08	2006-02-07	Immunex Corp.	FLK-1 binding proteins
EP1283268A3 (fr)	1996-08-23	2004-01-02	Ludwig Institute For Cancer Research	Facteur recombinant de croissance de cellules vascularies endothéliales D (VEGF-D)
CN1260835A (zh) *	1997-04-25	2000-07-19	科莱特诺医疗公司	截短的vegf相关蛋白质
SG117417A1 (en)	1998-02-06	2005-12-29	Collateral Therpeutics Inc	Variants of the angiogenic factor vascular endothelial cell growth factor: vegf
ATE556090T1 (de)	1998-11-10	2012-05-15	Ludwig Inst Cancer Res	Verkürzter, von blutplättchen abstammender wachstumsfaktor d, dafür kodierendes dns und deren verwendung
US7105481B2 (en)	1998-11-10	2006-09-12	Ludwig Institute For Cancer Research	Method for stimulating connective tissue growth or wound healing
DK1137773T3 (da)	1998-12-07	2008-12-08	Zymogenetics Inc	Væsktfaktorhomolog ZVEGF3
US6783953B1 (en)	1998-12-22	2004-08-31	Janssen Pharmaceutica N.V.	Vascular endothelial growth factor-X
AUPQ568100A0 (en) *	2000-02-16	2000-03-09	Amrad Operations Pty. Limited	A method for producing recombinant molecules
AU2002228841C1 (en)	2000-12-07	2006-11-23	Sangamo Biosciences, Inc	Regulation of angiogenesis with zinc finger proteins
US7067317B2 (en)	2000-12-07	2006-06-27	Sangamo Biosciences, Inc.	Regulation of angiogenesis with zinc finger proteins
US7981863B2 (en) *	2001-09-19	2011-07-19	Neuronova Ab	Treatment of Parkinson's disease with PDGF
ATE553122T1 (de)	2005-02-28	2012-04-15	Sangamo Biosciences Inc	Antiangiogene methoden und zusammensetzungen
CN100448892C (zh) *	2006-08-02	2009-01-07	中国人民解放军军事医学科学院基础医学研究所	抗肿瘤血管内皮生长因子受体vegf－r2抗原及其编码基因与应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5073492A (en) *	1987-01-09	1991-12-17	The Johns Hopkins University	Synergistic composition for endothelial cell growth
US5332671A (en) *	1989-05-12	1994-07-26	Genetech, Inc.	Production of vascular endothelial cell growth factor and DNA encoding same
US5194596A (en) *	1989-07-27	1993-03-16	California Biotechnology Inc.	Production of vascular endothelial cell growth factor
US5219739A (en) *	1989-07-27	1993-06-15	Scios Nova Inc.	DNA sequences encoding bVEGF120 and hVEGF121 and methods for the production of bovine and human vascular endothelial cell growth factors, bVEGF120 and hVEGF121
US5338671A (en) *	1992-10-07	1994-08-16	Eastman Kodak Company	DNA amplification with thermostable DNA polymerase and polymerase inhibiting antibody
EP0751992B1 (fr) *	1994-03-08	2005-11-09	Human Genome Sciences, Inc.	Facteur 2 de croissance endotheliale vasculaire
US5607918A (en) *	1995-03-01	1997-03-04	Ludwig Institute For Cancer Research	Vascular endothelial growth factor-B and DNA coding therefor
US5928939A (en) *	1995-03-01	1999-07-27	Ludwig Institute For Cancer Research	Vascular endothelial growth factor-b and dna coding therefor

1996
- 1996-02-22 EP EP96902810A patent/EP0815221B1/fr not_active Expired - Lifetime
- 1996-02-22 ES ES96902810T patent/ES2206558T3/es not_active Expired - Lifetime
- 1996-02-22 BR BR9607628-3A patent/BR9607628A/pt not_active Application Discontinuation
- 1996-02-22 CA CA002214439A patent/CA2214439C/fr not_active Expired - Lifetime
- 1996-02-22 KR KR1019970706109A patent/KR100414615B1/ko not_active Expired - Lifetime
- 1996-02-22 AT AT96902810T patent/ATE252600T1/de active
- 1996-02-22 WO PCT/AU1996/000094 patent/WO1996027007A1/fr not_active Ceased
- 1996-02-22 CN CNB961930357A patent/CN1194090C/zh not_active Expired - Lifetime
- 1996-02-22 NZ NZ301611A patent/NZ301611A/en not_active IP Right Cessation
- 1996-02-22 JP JP8525903A patent/JPH11500139A/ja not_active Withdrawn
- 1996-02-22 HU HU9800377A patent/HU223438B1/hu active IP Right Grant
- 1996-02-22 NZ NZ337634A patent/NZ337634A/en not_active IP Right Cessation
- 1996-02-22 DE DE69630442T patent/DE69630442T2/de not_active Expired - Lifetime
1997
- 1997-09-01 FI FI973571A patent/FI120153B/fi not_active IP Right Cessation
- 1997-09-02 NO NO19974035A patent/NO320839B1/no not_active IP Right Cessation
2000
- 2000-06-14 JP JP2000178462A patent/JP3683778B2/ja not_active Expired - Lifetime
2006
- 2006-11-20 US US11/602,055 patent/US20070135344A1/en not_active Abandoned

Also Published As

Publication number	Publication date
HU223438B1 (hu)	2004-07-28
NO974035D0 (no)	1997-09-02
CN1224464A (zh)	1999-07-28
FI973571A0 (fi)	1997-09-01
ATE252600T1 (de)	2003-11-15
EP0815221B1 (fr)	2003-10-22
HUP9800377A1 (hu)	1998-06-29
KR19980702702A (ko)	1998-08-05
NZ337634A (en)	2001-06-29
FI120153B (fi)	2009-07-15
US20070135344A1 (en)	2007-06-14
HK1002963A1 (en)	1998-09-30
WO1996027007A1 (fr)	1996-09-06
DE69630442D1 (de)	2003-11-27
JP2001037493A (ja)	2001-02-13
NZ301611A (en)	2000-02-28
EP0815221A1 (fr)	1998-01-07
NO974035L (no)	1997-11-03
FI973571L (fi)	1997-10-30
BR9607628A (pt)	1999-11-30
JPH11500139A (ja)	1999-01-06
EP0815221A4 (fr)	1998-12-09
ES2206558T3 (es)	2004-05-16
KR100414615B1 (ko)	2004-05-27
JP3683778B2 (ja)	2005-08-17
HUP9800377A3 (en)	2000-12-28
CN1194090C (zh)	2005-03-23
CA2214439A1 (fr)	1996-09-06
DE69630442T2 (de)	2004-08-19
CA2214439C (fr)	2002-12-17

Legal Events

Date	Code	Title	Description
2016-03-07	MK1K	Patent expired

Publication	Publication Date	Title
NO320839B1 (no)	2006-01-30	Isolert polypeptid, fremgangsmate for dets fremstilling, isolert nukleinsyremolekyl, isolert antistoff, antisensemolekyl, preparat, anvendelse av henholdsvis et polypeptid og et nukleinsyremolekyl, vertscelle samt vektor.
DE69733204T3 (de)	2012-03-08	Neuartige vegf-ähnliche faktoren
Prasad et al.	1992	Complementary DNA cloning of a novel epithelial cell marker protein, HME1, that may be down-regulated in neoplastic mammary cells
DE69734359T2 (de)	2006-07-06	Rekombinanter vaskulärer endothelzellen wachstumsfaktor d (vegf-d)
DE69931178T2 (de)	2007-02-22	Ein dem vaskularen endothelen wachstumsfaktor verwandtes protein aus orf virus nz10 bindet und aktiviert den säuger vegf rezeptor-2
DE69534351T2 (de)	2006-06-08	Motorneuronlebenserhaltungsgen: ein Gen für spinale Muskelatrophie
EP1923465A1 (fr)	2008-05-21	Protéine inhibitrice du trajet du signal WNT
DE69833211T2 (de)	2006-09-21	Humanes persephin
AU707513B2 (en)	1999-07-15	A novel growth factor and a genetic sequence encoding same
US7160991B1 (en)	2007-01-09	Vascular endothelial growth factor polypeptides
DE69936192T2 (de)	2008-01-31	Menschliches stanniocalcin und seine verwendung zur hemmung der adipogenese
Cohen et al.	1991	Isolation and sequence analysis of two intermediate filament cDNA clones from fish optic nerve
HK1002963B (en)	2004-04-23	A novel growth factor and a genetic sequence encoding same
IE912281A1 (en)	1992-01-01	New protein with cell-differentiation or cell-formation¹ability and recombinant process for the production
PL185293B1 (pl)	2003-04-30	Izolowany polipeptyd, izolowana cząsteczka kwasu nukleinowego, sposób otrzymywania polipeptydu, cząsteczka antysensowna, środek farmaceutyczny, komórka gospodarza oraz wektor
AU713198B2 (en)	1999-11-25	Cloning, expression and uses of a novel secreted protein, F-spondin
AU1947900A (en)	2000-06-01	Cloning, expression and uses of a novel secreted protein F-spondin